1. Estimating the Strength of Associations Between Prenatal Diet Quality and Child Developmental Outcomes: Results From a Large Prospective Pregnancy Cohort Study
- Author
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Anne Lise Brantsæter, Helle Margrete Meltzer, Tiril Cecilie Borge, Ragnhild Eek Brandlistuen, Heidi Aase, Ida Henriette Caspersen, and Guido Biele
- Subjects
Adult ,Male ,030309 nutrition & dietetics ,Epidemiology ,media_common.quotation_subject ,Original Contributions ,Child Behavior ,Norwegian ,Prenatal care ,Language Development ,03 medical and health sciences ,0302 clinical medicine ,Child Development ,Pregnancy ,Epidemiologi ,Medicine ,prenatal diet quality ,Humans ,030212 general & internal medicine ,Prospective Studies ,Child Behavior Checklist ,Prenatal Nutritional Physiological Phenomena ,VDP::Ernæring: 811 ,media_common ,Selection bias ,0303 health sciences ,business.industry ,Nutritional epidemiology ,Inverse probability weighting ,Infant ,Barns utvikling ,Child development ,language.human_language ,Bayesian modeling ,Kosthold i svangerskapet ,nutritional epidemiology ,child neurodevelopment ,VDP::Nutrition: 811 ,Child, Preschool ,Norwegian Mother and Child Cohort Study (MoBa) ,language ,Female ,business ,Demography ,Cohort study - Abstract
Our aim in this study was to estimate the strength of associations between prenatal diet quality and child behavioral, language, and motor functions in the Norwegian Mother and Child Cohort Study (1999–2008). We created a prenatal diet quality index (PDQI) based on adherence to Norwegian dietary guidelines. Child outcomes were defined as sum scores on the Child Behavior Checklist, the Ages and Stages Questionnaire, and the Child Development Index at ages 18, 36, and 60 months. Using a longitudinal cohort study design and Bayesian hierarchical modeling, we estimated association strengths using inverse probability weighting to account for selection bias. In total, 27,529 mother-child pairs were eligible for inclusion. A 1–standard-deviation increase in PDQI score was associated with an absolute reduction in outcome sum scores of 0.02–0.21 and a 3%–7% relative decrease, with larger decreases seen for language and motor functions than for behavioral functions. PDQI scores were inversely associated with all child functions, but the estimated strength of each association was low. The results indicate that the observed variations in PDQI scores in an industrialized Western society may not profoundly influence the child functions studied. Estimating the Strength of Associations Between Prenatal Diet Quality and Child Developmental Outcomes: Results From a Large Prospective Pregnancy Cohort Study
- Published
- 2019