286 results on '"Kozma, Sara C."'
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2. Data from Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR
3. Data from Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors
4. Supplementary Fig. S1 from Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors
5. Data from Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content
6. Suppl.Mat., Suppl. Table, Suppl. Figs Legends from Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR
7. Supplementary Data S1-S5, Table from Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content
8. Data from Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis
9. Supplementary Figures 1-4 from Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis
10. The Drosophila p70$^{\text{s}6\text{k}}$ Homolog Exhibits Conserved Regulatory Elements and Rapamycin Sensitivity
11. Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection
12. A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies
13. Targeting mTOR Signaling Pathways in Liver Disease
14. S6K-STING interaction regulates cytosolic DNA–mediated activation of the transcription factor IRF3
15. A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis
16. EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice
17. MYCN concurrence with SAHA-induced cell death in human neuroblastoma cells
18. Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage
19. Vesicular Stomatitis Virus Oncolysis Is Potentiated by Impairing mTORC1-dependent Type I IFN Production
20. Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
21. S6K1 controls pancreatic β cell size independently of intrauterine growth restriction
22. Cloning of the Mitogen-Activated S6 Kinase from Rat Liver Reveals an Enzyme of the Second Messenger Subfamily
23. Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death
24. Amino Acids Activate mTOR Complex 1 via Ca 2+/CaM Signaling to hVps34
25. mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
26. A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
27. Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
28. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
29. S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy
30. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
31. EPRS is a critical mTORC1S6K1 effector that influences adiposity in mice
32. Hypothalamic mTOR signaling regulates food intake
33. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
34. Phytohormones participate in an S6 kinase signal transduction pathway in Arabidopsis (1)
35. Targeting mTOR Signaling Pathways in Liver Disease
36. Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K. (Review articles)
37. Mammalian TOR: a homeostatic ATP sensor. (Reports)
38. Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage
39. Disruption of the p70s6k/p85s6k gene reveals a small mouse phenotype and a new functional S6 kinase
40. Hypoinsulinaemia, glucose intolerance and diminished β-cell size in S6K1-deficient mice
41. S6K1 deficiency protects against apoptosis in hepatocytes#
42. The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
43. Phosphorylation and activation of p70s6k by PDK1
44. Activation of p70/p85 S6 kinase by a pathway independent of p21ras
45. Proliferation, But Not Growth, Blocked by Conditional Deletion of 40S Ribosomal Protein S6
46. S6K
47. Drosophila S6 Kinase: A Regulator of Cell Size
48. Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content
49. Mitochondrial Complex I Activity Is Required for Maximal Autophagy
50. Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR
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