1. KVALITA ŽIVOTA OSOB S CUSHINGOVÝM SYNDROMEM.
- Author
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Kršková, Vladimíra, Kršek, Michal, and Hájková, Vanda
- Subjects
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CUSHING'S syndrome , *SOCIAL impact , *SYMPTOMS , *QUALITY of life , *RARE diseases - Abstract
Cushing’s syndrome is a rare disease caused by increased cortisol secretion, which is associated with significantly increased morbidity and mortality. Besides somatic signs and symptoms it is characterized also with impaired quality of life. The aim of this study was to find out how Cushing’s syndrome influences the quality of life in Czech Republic. 24 subjects with active Cushing’s syndrome (18 women, 6 men) aged 39,6 ± 13,9 yrs. And 75 healthy control subjects (64 women, 11 men) aged 39,4 ± 14,12 were examined using disease specific quality of life questionnaires (Cushig QoL) and semi structured and open interviews. Answers were statistically analysed using Mann-Whitney test. Result of our study demonstrated impaired quality of life in both, somatic, psychological and social consequences fields. Early intervention of stated disorders could lead to the improvement of quality of life as well as to the early recovery of affected subject [ABSTRACT FROM AUTHOR]
- Published
- 2019