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1. Posttransfusion Sepsis Attributable to Bacterial Contamination in Platelet Collection Set Manufacturing Facility, United States.

Author

Kracalik, Ian, Kent, Alyssa, Villa, Carlos, Gable, Paige, Annambhotla, Pallavi, McAllister, Gillian, Yokoe, Deborah, Oakeson, Kelly, Noble-Wang, Judith, Illoh, Orieji, Halpin, Alison, Eder, Anne, Basavaraju, Sridhar, and Langelier, Charles

Subjects
Acinetobacter calcoaceticus‒baumannii complex, Staphylococcus saprophyticus, United States, bacteria, bacterial contamination, blood safety, blood transfusions, manufacturing facility, platelet collection set, platelets, posttransfusion sepsis, Humans, United States, Blood Platelets, Platelet Transfusion, Sepsis, Blood Transfusion, Bacteria
Abstract

During May 2018‒December 2022, we reviewed transfusion-transmitted sepsis cases in the United States attributable to polymicrobial contaminated apheresis platelet components, including Acinetobacter calcoaceticus‒baumannii complex or Staphylococcus saprophyticus isolated from patients and components. Transfused platelet components underwent bacterial risk control strategies (primary culture, pathogen reduction or primary culture, and secondary rapid test) before transfusion. Environmental samples were collected from a platelet collection set manufacturing facility. Seven sepsis cases from 6 platelet donations from 6 different donors were identified in patients from 6 states; 3 patients died. Cultures identified Acinetobacter calcoaceticus‒baumannii complex in 6 patients and 6 transfused platelets, S. saprophyticus in 4 patients and 4 transfused platelets. Whole-genome sequencing showed environmental isolates from the manufacturer were closely related genetically to patient and platelet isolates, indicating the manufacturer was the most probable source of recurrent polymicrobial contamination. Clinicians should maintain awareness of possible transfusion-transmitted sepsis even when using bacterial risk control strategies.

Published
2023

2. Estimated Effectiveness of JYNNEOS Vaccine in Preventing Mpox: A Multijurisdictional Case-Control Study — United States, August 19, 2022–March 31, 2023

Author

Dalton, Alexandra F, Diallo, Alpha Oumar, Chard, Anna N, Moulia, Danielle L, Deputy, Nicholas P, Fothergill, Amy, Kracalik, Ian, Wegner, Christopher W, Markus, Tiffanie M, Pathela, Preeti, Still, William L, Hawkins, Sam, Mangla, Anil T, Ravi, Nivedita, Licherdell, Erin, Britton, Amber, Lynfield, Ruth, Sutton, Melissa, Hansen, AmberJean P, Betancourt, Gabriela S, Rowlands, Jemma V, Chai, Shua J, Fisher, Rebecca, Danza, Phoebe, Farley, Monica, Zipprich, Jennifer, Prahl, Gregory, Wendel, Karen A, Niccolai, Linda, Castilho, Jessica L, Payne, Daniel C, Cohn, Amanda C, Feldstein, Leora R, Group, CDC Multijurisdictional Mpox Case-Control Study, Group, CDC Multijurisdictional Mpox Case Control Study, Saadeh, Kayla, Snyder, Robert E, Anderson, Madeline, Anguiano, Vanessa Aryana, Nadle, Joelle, Rothrock, Gretchen, Jones, Sydney, Duval, Lauren, Herlihy, Rachel, Stringer, Ginger, Weber, Robyn, Phan, Quyen, Sosa, Lynn, Meek, James, Lee, Michelle, Morrow, Allison S, Willut, Christina, Carlson, Jesse, Kamis, Kevin, Nishiyama, Masayo, Simien, Gena, Colasanti, Jonathan, van der Woude, Tamsin M, Archer, Roxanne, Finn, Lauren, Lam, Jane, Moulton, Bret, Peterson, Erin, Bolan, Robert, Garcia-Lopez, Gabriel, Como-Sabetti, Kathryn, Ruff, Anna, Schneider, Dakota, Robinson, Tracy, Anderson, Bridget J, Engesser, Kerianne, McGuire, Suzanne, Rowe, Adam, Pride, Christopher, Mitchell, Jaxon, Tourkina, Yelena, Cieslak, Paul R, Fill, Mary Margaret, Wiedeman, Caleb, Dumyati, Ghinwa, Felsen, Christina, Lewnard, Joseph A, Akoko, Bentley, Mansilla-Dubon, Kristyne, Ndi, Danielle, Talbot, H Keipp, Tiwari, Sweta, and Wyatt, Dayna

Subjects
Rare Diseases, Immunization, Infectious Diseases, Vaccine Related, Emerging Infectious Diseases, Prevention, 3.4 Vaccines, Prevention of disease and conditions, and promotion of well-being, Infection, Good Health and Well Being, Adult, Male, Humans, United States, Homosexuality, Male, Case-Control Studies, Monkeypox, Sexual and Gender Minorities, Smallpox Vaccine, CDC Multijurisdictional Mpox Case-Control Study Group, CDC Multijurisdictional Mpox Case Control Study Group, General & Internal Medicine
Abstract

As of March 31, 2023, more than 30,000 monkeypox (mpox) cases had been reported in the United States in an outbreak that has disproportionately affected gay, bisexual, and other men who have sex with men (MSM) and transgender persons (1). JYNNEOS vaccine (Modified Vaccinia Ankara vaccine, Bavarian Nordic) was approved by the Food and Drug Administration (FDA) in 2019 for the prevention of smallpox and mpox via subcutaneous injection as a 2-dose series (0.5 mL per dose, administered 4 weeks apart) (2). To expand vaccine access, an Emergency Use Authorization was issued by FDA on August 9, 2022, for dose-sparing intradermal injection of JYNNEOS as a 2-dose series (0.1 mL per dose, administered 4 weeks apart) (3). Vaccination was available to persons with known or presumed exposure to a person with mpox (postexposure prophylaxis [PEP]), as well as persons at increased risk for mpox or who might benefit from vaccination (preexposure mpox prophylaxis [PrEP]) (4). Because information on JYNNEOS vaccine effectiveness (VE) is limited, a matched case-control study was conducted in 12 U.S. jurisdictions,† including nine Emerging Infections Program sites and three Epidemiology and Laboratory Capacity sites,§ to evaluate VE against mpox among MSM and transgender adults aged 18-49 years. During August 19, 2022-March 31, 2023, a total of 309 case-patients were matched to 608 control patients. Adjusted VE was 75.2% (95% CI = 61.2% to 84.2%) for partial vaccination (1 dose) and 85.9% (95% CI = 73.8% to 92.4%) for full vaccination (2 doses). Adjusted VE for full vaccination by subcutaneous, intradermal, and heterologous routes of administration was 88.9% (95% CI = 56.0% to 97.2%), 80.3% (95% CI = 22.9% to 95.0%), and 86.9% (95% CI = 69.1% to 94.5%), respectively. Adjusted VE for full vaccination among immunocompromised participants was 70.2% (95% CI = -37.9% to 93.6%) and among immunocompetent participants was 87.8% (95% CI = 57.5% to 96.5%). JYNNEOS is effective at reducing the risk for mpox. Because duration of protection of 1 versus 2 doses remains unknown, persons at increased risk for mpox exposure should receive the 2-dose series as recommended by the Advisory Committee on Immunization Practices (ACIP),¶ regardless of administration route or immunocompromise status.

Published
2023

3. Overview of U.S. COVID-19 vaccine safety surveillance systems

Author

Gee, Julianne, Shimabukuro, Tom T., Su, John R., Shay, David, Ryan, Margaret, Basavaraju, Sridhar V., Broder, Karen R., Clark, Matthew, Buddy Creech, C., Cunningham, Francesca, Goddard, Kristin, Guy, Harrison, Edwards, Kathryn M., Forshee, Richard, Hamburger, Tanya, Hause, Anne M., Klein, Nicola P., Kracalik, Ian, Lamer, Chris, Loran, David A., McNeil, Michael M., Montgomery, Jay, Moro, Pedro, Myers, Tanya R., Olson, Christine, Oster, Matthew E., Sharma, Andrea J., Schupbach, Ryan, Weintraub, Eric, Whitehead, Brett, and Anderson, Steven

Published
2024
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4. Monkeypox Virus Infections After 2 Preexposure Doses of JYNNEOS Vaccine--United States, May 2022-May 2024

Author

Guagliardo, Sarah Anne J., Kracalik, Ian, Carter, Rosalind J., Braden, Christopher, Free, Rebecca, Hamal, Mukesh, Tuttle, Alexandra, McCollum, Andrea M., and Rao, Agam K.

Subjects
Vaccination -- Health aspects -- Comparative analysis, Medical research -- Comparative analysis -- Health aspects, Medicine, Experimental -- Comparative analysis -- Health aspects, Infection -- Comparative analysis -- Health aspects, Vaccines -- Health aspects -- Comparative analysis, Health
Abstract

Introduction JYNNEOS is a replication-deficient orthopoxvirus vaccine approved as a 2-dose series for prevention of smallpox and mpox. * This product was administered to nearly all vaccinated U.S. persons with [...]

Published
2024

5. The global distribution of Bacillus anthracis and associated anthrax risk to humans, livestock and wildlife

Author

Carlson, Colin J, Kracalik, Ian T, Ross, Noam, Alexander, Kathleen A, Hugh-Jones, Martin E, Fegan, Mark, Elkin, Brett T, Epp, Tasha, Shury, Todd K, Zhang, Wenyi, Bagirova, Mehriban, Getz, Wayne M, and Blackburn, Jason K

Subjects
Microbiology, Biological Sciences, Prevention, Anthrax, Vaccine Related, Infectious Diseases, Emerging Infectious Diseases, Rare Diseases, Biodefense, Aetiology, 2.2 Factors relating to the physical environment, Infection, Life on Land, Animal Diseases, Animals, Animals, Wild, Bacillus anthracis, Disease Outbreaks, Environmental Microbiology, Geography, Humans, Livestock, Models, Biological, Public Health, Risk Assessment, Risk Factors, Medical Microbiology
Abstract

Bacillus anthracis is a spore-forming, Gram-positive bacterium responsible for anthrax, an acute infection that most significantly affects grazing livestock and wild ungulates, but also poses a threat to human health. The geographic extent of B. anthracis is poorly understood, despite multi-decade research on anthrax epizootic and epidemic dynamics; many countries have limited or inadequate surveillance systems, even within known endemic regions. Here, we compile a global occurrence dataset of human, livestock and wildlife anthrax outbreaks. With these records, we use boosted regression trees to produce a map of the global distribution of B. anthracis as a proxy for anthrax risk. We estimate that 1.83 billion people (95% credible interval (CI): 0.59-4.16 billion) live within regions of anthrax risk, but most of that population faces little occupational exposure. More informatively, a global total of 63.8 million poor livestock keepers (95% CI: 17.5-168.6 million) and 1.1 billion livestock (95% CI: 0.4-2.3 billion) live within vulnerable regions. Human and livestock vulnerability are both concentrated in rural rainfed systems throughout arid and temperate land across Eurasia, Africa and North America. We conclude by mapping where anthrax risk could disrupt sensitive conservation efforts for wild ungulates that coincide with anthrax-prone landscapes.

Published
2019

6. Extensively Drug-Resistant Carbapenemase-Producing Pseudomonas aeruginosa and Medical Tourism from the United States to Mexico, 2018-2019

Author

Kracalik, Ian, Ham, D. Cal, McAllister, Gillian, Smith, Amanda R., Vowles, Maureen, Kauber, Kelly, Zambrano, Melba, Rodriguez, Gretchen, Garner, Kelley, Chorbi, Kaitlyn, Cassidy, P. Maureen, McBee, Shannon, Stoney, Rhett J., Moser, Kathleen, Villarino, Margarita E., Zazueta, Oscar E., Bhatnagar, Amelia, Sula, Erisa, Stanton, Richard A., Brown, Allison C., Halpin, Alison L., Epstein, Lauren, and Walters, Maroya Spalding

Subjects
Epidemics -- Statistics -- Risk factors -- United States -- Mexico, Pseudomonas aeruginosa infections -- Risk factors -- Statistics, Drug resistance in microorganisms -- Statistics, Cross infection -- Statistics -- Risk factors, Obesity -- Surgery, Nosocomial infections -- Statistics -- Risk factors, Hospital patients -- Statistics, Medical tourism -- Statistics, Health
Abstract

In the United States, 20% of Pseudomonas aeruginosa from adult device-associated healthcare-associated infections and 9% from surgical site infections are not susceptible to carbapenem antimicrobial drugs (1). However, only 1%-3% [...]

Published
2022
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7. Coronavirus Disease Contact Tracing Outcomes and Cost, Salt Lake County, Utah, USA, March-May 2020

Author

Fields, Victoria L., Kracalik, Ian T., Carthel, Christina, Lopez, Adriana, Schwartz, Amy, Lewis, Nathaniel M., Bray, Mackenzie, Claflin, Carlene, Jorgensen, Kilee, Khong, Ha, Richards, Walter, Risk, Ilene, Smithee, Maureen, Clawson, Madison, Booth, Lee Cherie, Scribellito, Tara, Lowry, Jason, Huynh, Jessica, Davis, Linda, Birch, Holly, Tran, Tiffany, Walker, Joseph, Fry, Alicia, Hall, Aron, Baker, Jodee, Pevzner, Eric, Dunn, Angela C., Tate, Jacqueline E., Kirking, Hannah L., Kiphibane, Tair, and Tran, Cuc H.

Subjects
Salt Lake County, Utah -- Health aspects, Epidemics -- Statistics -- Control -- United States, Contact tracing -- Methods -- Economic aspects, Health
Abstract

By July 2021, >33 million cases of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), were documented in the United States, and most cases involved contact [...]

Published
2021
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8. Ehrlichiosis and Anaplasmosis among Transfusion and Transplant Recipients in the United States

Author

Mowla, Sanjida J., Drexler, Naomi A., Cherry, Cara C., Annambholta, Pallavi D., Kracalik, Ian T., and Basavaraju, Sridhar V.

Subjects
Anaplasmosis -- Statistics -- Risk factors, Cross infection -- Statistics -- Risk factors, Blood transfusion -- Complications and side effects -- Statistics, Disease transmission -- Risk factors -- Statistics, Nosocomial infections -- Statistics -- Risk factors, Ehrlichiosis -- Statistics -- Risk factors, Organ transplant recipients -- Health aspects -- Statistics, Health
Abstract

In support of improving patient care, this activity has been planned and implemented by Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is jointly accredited by the Accreditation Council for [...]

Published
2021
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13. High Case-Fatality Rate for Human Anthrax, Northern Ghana, 2005-2016

Author

Blackburn, Jason K., Kenu, Ernest, Asiedu-Bekoe, Franklin, Sarkodie, Badu, Kracalik, Ian T., Bower, William A., Stoddard, Robyn A., and Traxler, Rita M.

Subjects
Mortality -- Analysis -- Ghana, Anthrax -- Analysis -- Patient outcomes, Health
Abstract

Despite being one of the earliest diseases described, anthrax, caused by infection with the bacterium Bacillus anthracis, remains a global public health concern, especially in resource-limited, rural agricultural areas, including [...]

Published
2021
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14. SARS-CoV-2 Infections among Recent Organ Recipients, March-May 2020, United States

Author

Jones, Jefferson M., Kracalik, Ian, Rana, Meenakshi M., Nguyen, Ann, Keller, Brian C., Mishkin, Aaron, Hoopes, Charles, Kaleekal, Thomas, Humar, Abhinav, Vilaro, Juan, Im, Gene, Smith, Lou, Justice, April, Leaumont, Collette, Lindstrom, Stephen, Whitaker, Brett, La Hoz, Ricardo M., Michaels, Marian G., Klassen, David, Kuhnert, Wendi, and Basavaraju, Sridhar V.

Subjects
Infection control -- Evaluation, Donation of organs, tissues, etc. -- Health aspects, Health
Abstract

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been reported in organ transplant recipients, it is unclear whether SARS-CoV-2 can be transmitted from organ donors to recipients (1) [...]

Published
2021
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16. Bacterial and Fungal Infections in Persons Who Inject Drugs — Western New York, 2017

Author

Hartnett, Kathleen P., Jackson, Kelly A., Felsen, Christina, McDonald, Robert, Bardossy, Ana Cecilia, Gokhale, Runa H., Kracalik, Ian, Lucas, Todd, McGovern, Olivia, Van Beneden, Chris A., Mendoza, Michael, Bohm, Michele, Brooks, John T., Asher, Alice K., Magill, Shelley S., Fiore, Anthony, Blog, Debra, Dufort, Elizabeth M., See, Isaac, and Dumyati, Ghinwa

Published
2019

17. Verona Integron-Encoded Metallo-β-Lactamase–Producing Carbapenem-Resistant Pseudomonas aeruginosa Infections in U.S. Residents Associated with Invasive Medical Procedures in Mexico, 2015–2018

Author

Kracalik, Ian, Ham, Cal, Smith, Amanda R., Vowles, Maureen, Kauber, Kelly, Zambrano, Melba, Rodriguez, Gretchen, Garner, Kelley, Chorbi, Kaitlyn, Cassidy, P. Maureen, McBee, Shannon, Stoney, Rhett, Brown, Allison C., Moser, Kathleen, Villarino, Margarita E., and Walters, Maroya Spalding

Published
2019

18. Estimated Effectiveness of JYNNEOS Vaccine in Preventing Mpox: A Multijurisdictional Case-Control Study--United States, August 19, 2022-March 31, 2023

Author

Dalton, Alexandra F., Diallo, Alpha Oumar, Chard, Anna N., Moulia, Danielle L., Deputy, Nicholas P., Fothergill, Amy, Kracalik, Ian, Wegner, Christopher W., Markus, Tiffanie M., Pathela, Preeti, Still, William L., Hawkins, Sam, Mangla, Anil T., Ravi, Nivedita, Licherdell, Erin, Britton, Amber, Lynfield, Ruth, Sutton, Melissa, Hansen, AmberJean P., Betancourt, Gabriela S., Rowlands, Jemma V., Chai, Shua J., Fisher, Rebecca, Danza, Phoebe, Farley, Monica, Zipprich, Jennifer, Prahl, Gregory, Wendel, Karen A., Niccolai, Linda, Castilho, Jessica L., Payne, Daniel C., Cohn, Amanda C., and Feldstein, Leora R.

Subjects
United States. Food and Drug Administration, Medical research, Medicine, Experimental, Transgender people, Drug approval, Vaccines, Health
Abstract

As of March 31, 2023, more than 30,000 monkeypox (mpox) cases had been reported in the United States in an outbreak that has disproportionately affected gay, bisexual, and other men [...]

Published
2023

20. Notes from the Field: Emergence of an Mpox Cluster Primarily Affecting Persons Previously Vaccinated Against Mpox — Chicago, Illinois, March 18–June 12, 2023

Author

Faherty, Emily A.G., primary, Holly, Taylor, additional, Ogale, Yasmin P., additional, Crisler, Gordon, additional, Becht, Ashley, additional, Kern, David, additional, Nicolae, Lavinia, additional, Spencer, Hillary, additional, Wasz, Michael, additional, Kerins, Janna L., additional, Kittner, Alyse, additional, Staton, Amber, additional, Hardnett, Carla, additional, Hutson, Christina, additional, Gigante, Crystal M., additional, Quilter, Laura, additional, Kracalik, Ian, additional, Black, Stephanie, additional, McCollum, Andrea M., additional, Rao, Agam K., additional, and Tabidze, Irina, additional

Published
2023
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22. Emergence of an Mpox Cluster Primarily Affecting Persons Previously Vaccinated Against Mpox--Chicago, Illinois, March 18-June 12, 2023

Author

Faherty, Emily A.G., Holly, Taylor, Ogale, Yasmin P., Crisler, Gordon, Becht, Ashley, Kern, David, Nicolae, Lavinia, Spencer, Hillary, Wasz, Michael, Kerins, Janna L., Kittner, Alyse, Staton, Amber, Hardnett, Carla, Hutson, Christina, Gigante, Crystal M., Quilter, Laura, Kracalik, Ian, Black, Stephanie, McCollum, Andrea M., Rao, Agam K., and Tabidze, Irina

Subjects
Vaccination, Public health, Health, ACAM2000 (Vaccine)
Abstract

During April 17-May 5, 2023, 13 monkeypox (mpox) cases were reported to the Chicago Department of Public Health (CDPH) after 2 months during which only a single case had been [...]

Published
2023

23. Epidemiology of SARS-CoV-2 transmission and superspreading in Salt Lake County, Utah, March–May 2020

Author

Walker, Joseph, primary, Tran, Tiffany, additional, Lappe, Brooke, additional, Gastanaduy, Paul, additional, Paul, Prabasaj, additional, Kracalik, Ian T., additional, Fields, Victoria L., additional, Lopez, Adriana, additional, Schwartz, Amy, additional, Lewis, Nathaniel M., additional, Tate, Jacqueline E., additional, Kirking, Hannah L., additional, Hall, Aron J., additional, Pevzner, Eric, additional, Khong, Ha, additional, Smithee, Maureen, additional, Lowry, Jason, additional, Dunn, Angela, additional, Kiphibane, Tair, additional, and Tran, Cuc H., additional

Published
2023
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24. Notes from the Field: Emergence of an Mpox Cluster Primarily Affecting Persons Previously Vaccinated Against Mpox — Chicago, Illinois, March 18–June 12, 2023

Author

Faherty, Emily A. G., primary, Holly, Taylor, additional, Ogale, Yasmin P., additional, Crisler, Gordon, additional, Becht, Ashley, additional, Kern, David, additional, Nicolae, Lavinia, additional, Spencer, Hillary, additional, Wasz, Michael, additional, Kerins, Janna L., additional, Kittner, Alyse, additional, Staton, Amber, additional, Hardnett, Carla, additional, Hutson, Christina, additional, Gigante, Crystal M., additional, Quilter, Laura, additional, Kracalik, Ian, additional, Black, Stephanie, additional, McCollum, Andrea M., additional, Rao, Agam K., additional, and Tabidze, Irina, additional

Published
2023
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26. Outcomes at least 90 days since onset of myocarditis after mRNA COVID-19 vaccination in adolescents and young adults in the USA: a follow-up surveillance study

Author

Kracalik, Ian, primary, Oster, Matthew E, additional, Broder, Karen R, additional, Cortese, Margaret M, additional, Glover, Maleeka, additional, Shields, Karen, additional, Creech, C Buddy, additional, Romanson, Brittney, additional, Novosad, Shannon, additional, Soslow, Jonathan, additional, Walter, Emmanuel B, additional, Marquez, Paige, additional, Dendy, Jeffrey M, additional, Woo, Jared, additional, Valderrama, Amy L, additional, Ramirez-Cardenas, Alejandra, additional, Assefa, Agape, additional, Campbell, M Jay, additional, Su, John R, additional, Magill, Shelley S, additional, Shay, David K, additional, Shimabukuro, Tom T, additional, Basavaraju, Sridhar V, additional, Campbell, Paula, additional, Anugwom, Chidera, additional, Arvelo Jefferson, Colenda, additional, Badger, Kimberly, additional, Bafford, Nastocia, additional, Barnes, Chandra, additional, Boles, Stephanie, additional, Collins, Emory, additional, Desai, Mitesh, additional, Dulski, Theresa, additional, Dyleski, Barbara, additional, Edwards, Kathryn, additional, Feyereisen, Melanie, additional, Gonsahn, Stephanie, additional, Gregory, Tchernavia, additional, Gunta, Jyothi, additional, Jacobs Slifka, Kara, additional, Kabore, Charlotte, additional, Kapella, Bryan K., additional, Karol, Susan, additional, Kennebrew, Kalah, additional, Kluisza, Nancy, additional, Lang, Sean, additional, Lanier Gholston, Labretta, additional, Law, Marcella, additional, Lehman, Jennifer, additional, Mazurek, Jacek M., additional, McGruder, Henraya, additional, McNamara, Kiara, additional, Moore, Maria-Luisa, additional, Moro, Pedro, additional, Moroney, John F., additional, Museru, Oidda, additional, Nale, Cassandra, additional, Neiman, Andi, additional, Newsome, Kim, additional, Odom, Erika, additional, Pantazides, Brooke, additional, Patel, Suchita, additional, Rao, Agam, additional, Reynolds, Laura, additional, Robinson, Sonya, additional, Ruberg, Frederick L., additional, Schaeffer, Tammy, additional, Solanky, Dipesh, additional, Sperling, Laurence, additional, Stanley, Toscha, additional, Sullivan, Regina, additional, Taylor, Allan, additional, Thomas, Kimberly, additional, Thompson, Shayle, additional, Tola, Jigsa, additional, Tran, Cuc H., additional, Wiersma, Steven, additional, and Works, Kimberly, additional

Published
2022
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28. Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Through Solid Organ Transplantation and Outcomes of Coronavirus Disease 2019 Among Recent Transplant Recipients

Author

Free, Rebecca J, primary, Annambhotla, Pallavi, additional, La Hoz, Ricardo M, additional, Danziger-Isakov, Lara, additional, Jones, Jefferson M, additional, Wang, Lijuan, additional, Sankthivel, Senthil, additional, Levi, Marilyn E, additional, Michaels, Marian G, additional, Kuhnert, Wendi, additional, Klassen, David, additional, Basavaraju, Sridhar V, additional, and Kracalik, Ian T, additional

Published
2022
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30. Household-level spatiotemporal patterns of incidence of cholera, Haitii, 2011

Author

Blackburn, Jason K., Diamond, Ulrica, Kracalik, Ian T., Widmer, Jocelyn, Brown, Will, Morrissey, B. David, Alexander, Kathleen A., Curtis, Andrew J., Ali, Afsar, and Morris, Jr., J. Glenn

Subjects
Cholera toxin -- Analysis, Cholera -- Analysis, Health
Abstract

The 2010-2011 Haiti cholera epidemic was one of the largest worldwide in recent history. Before the initial outbreak, cholera had not been reported in Haiti for at least 100 years [...]

Published
2014
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31. Human cutaneous anthrax, Georgia 2010-2012

Author

Kracalik, Ian, Malania, Lile, Tsertsvadze, Nikoloz, Manvelyan, Julietta, Bakanidze, Lela, Imnadze, Paata, Tsanava, Shota, and Blackburn, Jason K.

Subjects
Anthrax -- Risk factors -- Demographic aspects -- Research, Health
Abstract

Anthrax, a zoonosis caused by the bacterium Bacillus Aanthracis, is associated with rural areas or agricultural production (1-3). Human infections often result directly from contact with infected livestock or contaminated [...]

Published
2014
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32. Impact of the early COVID‐19 pandemic on blood utilization in the United States: a time‐series analysis of data reported to the National Healthcare Safety Network Hemovigilance Module

Author

Kracalik, Ian, Mowla, Sanjida, Katz, Louis, Cumming, Melissa, Sapiano, Matthew R. P., and Basavaraju, Sridhar V.

Subjects
SARS-CoV-2, Blood Safety, Data Collection, COVID-19, Blood Component Transfusion, Interrupted Time Series Analysis, United States, Elective Surgical Procedures, Humans, Supplement Article, Blood Transfusion, Delivery of Health Care, Pandemics, Facilities and Services Utilization
Abstract

Introduction The coronavirus disease 2019 (COVID‐19) pandemic has disrupted healthcare services worldwide. However, little has been reported regarding the impact on blood utilization. We quantified the impact of COVID‐19 on blood utilization and discards among facilities reporting to the National Healthcare Safety Network Hemovigilance Module. Methods Facilities continuously reporting data, during January 2016–June 2020, on transfused and discarded blood components, stratified by component type (red blood cells [RBC], platelets and plasma), were included. Interrupted time‐series analysis with generalized estimating equations, adjusting for facility surgical volume and seasonality, was used to quantify changes in blood utilization and discards relative to a Centers for Medicare & Medicaid Services notification delaying non‐essential medical procedures (March 2020). Results Seventy‐two facilities included in the analyses, on average, transfused 44,548 and discarded 2202 blood components monthly. Following the March 2020 notification and after multivariable adjustment, RBC and platelet utilization declined, −14.8% (p

Published
2021

33. How do I… facilitate a rapid response to a public health emergency requiring plasma collection with a public–private partnership?

Author

Miller, Maureen J., primary, Skrzekut, Adam, additional, Kracalik, Ian, additional, Jones, Jefferson M., additional, Lofy, Kathryn H., additional, Konkle, Barbara A., additional, Haley, N. Rebecca, additional, Duvenhage, Michael, additional, Bonnett, Tyler, additional, Holbrook, Michael, additional, Higgs, Elizabeth, additional, Basavaraju, Sridhar V., additional, and Paranjape, Suman, additional

Published
2021
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37. Notes from the Field: Unexplained Dermatologic, Respiratory, and Ophthalmic Symptoms Among Health Care Personnel at a Hospital — West Virginia, November 2017–January 2018

Author

Lucas, Todd J., primary, Holodniy, Mark, additional, de Perio, Marie A., additional, Perkins, Kiran M., additional, Benowitz, Isaac, additional, Jackson, David, additional, Kracalik, Ian, additional, Grant, Michael, additional, Oda, Gina, additional, and Powell, Krista M., additional

Published
2019
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38. 1890. Missed Clinical Opportunities to Prevent Infections and Treat Substance Use Disorder (SUD) in People Who Inject Drugs (PWID)

Author

Bardossy, Ana C, primary, Gokhale, Runa H, additional, Hartnett, Kathleen, additional, Hatfield, Kelly M, additional, Jackson, Kelly A, additional, Felsen, Christina B, additional, McDonald, Robert, additional, Kracalik, Ian, additional, Lucas, Todd, additional, McGovern, Olivia L, additional, Van Beneden, Chris, additional, Vallabhaneni, Snigdha, additional, Williams, Sabrina R, additional, Mendoza, Michael, additional, Bohm, Michele K, additional, Brooks, John, additional, Asher, Alice K, additional, Magill, Shelley S, additional, Fiore, Anthony, additional, Blog, Debra, additional, Dufort, Elizabeth, additional, See, Isaac, additional, and Dumyati, Ghinwa, additional

Published
2019
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39. Analyzing the spatial and temporal distribution of human brucellosis in Azerbaijan (1995 - 2009) using spatial and spatio-temporal statistics

Author

Abdullayev Rakif, Kracalik Ian, Ismayilova Rita, Ustun Narmin, Talibzade Ayden, and Blackburn Jason K

Subjects
Brucellosis, Spatio-temporal analysis, Azerbaijan, Former Soviet Union, Serology, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Human brucellosis represents a significant burden to public and veterinary health globally, including the republic of Azerbaijan. The purpose of this study was to examine and describe the spatial and temporal aspects of the epidemiology of human brucellosis in Azerbaijan from 1995 to 2009. Methods A Geographic information system (GIS) was used to identify potential changes in the spatial and temporal distribution of human brucellosis in Azerbaijan during the study period. Epidemiological information on the age, gender, date, and location of incident cases were obtained from disease registries housed at the Republican Anti-Plague station in Baku. Cumulative incidences per 100,000 populations were calculated at the district level for three, 5-year periods. Spatial and temporal cluster analyses were performed using the Local Moran’s I and the Ederer-Myer-Mantel (EMM) test. Results A total of 7,983 cases of human brucellosis were reported during the 15-year study period. Statistically significant spatial clusters were identified in each of three, five year time periods with cumulative incidence rates ranging from 101.1 (95% CI: 82.8, 124.3) to 203.0 (95% CI; 176.4, 234.8). Spatial clustering was predominant in the west early in the study during period 1 and then in the east during periods 2 and 3. The EMM test identified a greater number of statistically significant temporal clusters in period 1 (1995 to 1999). Conclusion These results suggest that human brucellosis persisted annually in Azerbaijan across the study period. The current situation necessitates the development of appropriate surveillance aimed at improving control and mitigation strategies in order to help alleviate the current burden of disease on the population. Areas of concern identified as clusters by the spatial-temporal statistical analyses can provide a starting point for implementing targeted intervention efforts.

Published
2012
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40. Notes from the Field:Verona Integron-Encoded Metallo-β-Lactamase–Producing Carbapenem-ResistantPseudomonas aeruginosaInfections in U.S. Residents Associated with Invasive Medical Procedures in Mexico, 2015–2018

Author

Kracalik, Ian, primary, Ham, Cal, additional, Smith, Amanda R., additional, Vowles, Maureen, additional, Kauber, Kelly, additional, Zambrano, Melba, additional, Rodriguez, Gretchen, additional, Garner, Kelley, additional, Chorbi, Kaitlyn, additional, Cassidy, P. Maureen, additional, McBee, Shannon, additional, Stoney, Rhett, additional, Brown, Allison C., additional, Moser, Kathleen, additional, Villarino, Margarita E., additional, and Walters, Maroya Spalding, additional

Published
2019
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41. 1230. Epidemiology and Risk Factors for Recurrent Invasive Methicillin-Resistant Staphylococcus aureus Infection: nine US States, 2006–2013

Author

Kracalik, Ian, primary, Jackson, Kelly, additional, Nadle, Joelle, additional, Bamberg, Wendy, additional, Petit, Susan, additional, Ray, Susan M, additional, Lynfield, Ruth, additional, Harrison, Lee H, additional, Townes, John M, additional, Dumyati, Ghinwa, additional, Schaffner, William, additional, Lake, Jason, additional, and See, Isaac, additional

Published
2018
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42. The global distribution of Bacillus anthracis and associated anthrax risk to humans, livestock, and wildlife

Author

Carlson, Colin J., primary, Kracalik, Ian T., additional, Ross, Noam, additional, Alexander, Kathleen, additional, Hugh-Jones, Martin E., additional, Fegan, Mark, additional, Elkin, Brett, additional, Epp, Tasha, additional, Shury, Todd K., additional, Bagirova, Mehriban, additional, Getz, Wayne M., additional, and Blackburn, Jason K., additional

Published
2018
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43. Modeling the environmental suitability of anthrax in Ghana and estimating populations at risk: Implications for vaccination and control

Author

Kracalik, Ian T., primary, Kenu, Ernest, additional, Ayamdooh, Evans Nsoh, additional, Allegye-Cudjoe, Emmanuel, additional, Polkuu, Paul Nokuma, additional, Frimpong, Joseph Asamoah, additional, Nyarko, Kofi Mensah, additional, Bower, William A., additional, Traxler, Rita, additional, and Blackburn, Jason K., additional

Published
2017
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45. Cholera in Cameroon, 2000-2012: Spatial and Temporal Analysis at the Operational (Health District) and Sub Climate Levels

Author

Ngwa, Moise C., primary, Liang, Song, additional, Kracalik, Ian T., additional, Morris, Lillian, additional, Blackburn, Jason K., additional, Mbam, Leonard M., additional, Ba Pouth, Simon Franky Baonga, additional, Teboh, Andrew, additional, Yang, Yang, additional, Arabi, Mouhaman, additional, Sugimoto, Jonathan D., additional, and Morris, John Glenn, additional

Published
2016
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48. Genetic Studies of Vibrio cholerae in South West Cameroon—A Phylogenetic Analysis of Isolates from the 2010-2011 Epidemic

Author

Ngwa, Moise C., primary, Masalla, Thomas, additional, Esemu, Seraphine, additional, Fumoloh, Foche Francis, additional, Kracalik, Ian, additional, Cella, Eleonora, additional, Alam, Meer Taifur, additional, Akoachere, Jane-Francis, additional, Liang, Song, additional, Salemi, Marco, additional, Morris, J. Glenn, additional, Ali, Afsar, additional, and Ndip, Lucy M., additional

Published
2016
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50. Environmental Monitoring and Surveillance of Rodents and Vectors for Francisella tularensis Following Outbreaks of Human Tularemia in Georgia

Author

Elashvili, Eka, primary, Kracalik, Ian, additional, Burjanadze, Irma, additional, Datukishvili, Sophio, additional, Chanturia, Gvantsa, additional, Tsertsvadze, Nikoloz, additional, Beridze, Levan, additional, Shavishvili, Merab, additional, Dzneladze, Archil, additional, Grdzelidze, Marina, additional, Imnadze, Paata, additional, Pearson, Andrew, additional, and Blackburn, Jason K., additional

Published
2015
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