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1,683 results on '"Kramer, Christopher M."'

2. Protein Biomarkers of Adverse Clinical Features and Events in Sarcomeric Hypertrophic Cardiomyopathy

Author

Tahir, Usman A., Kolm, Paul, Kwong, Raymond Y., Desai, Milind Y., Dolman, Sarahfaye F., Deng, Shuliang, Appelbaum, Evan, Desvigne-Nickens, Patrice, DiMarco, John P., Tiwari, Gaurav, Friedrich, Matthias G., Zelaya-Portillo, Julissa H., Jerosch-Herold, Michael, Kim, Dong-Yun, Maron, Martin S., Piechnik, Stefan K., Schulz-Menger, Jeanette, Watkins, Hugh, Weintraub, William S., Neubauer, Stefan, Kramer, Christopher M., Jarolim, Petr, Gerszten, Robert E., and Ho, Carolyn Y.

Published
2024
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3. Effect of Aficamten on Cardiac Structure and Function in Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM CMR Substudy

Author

Masri, Ahmad, Cardoso, Rhanderson N., Abraham, Theodore P., Claggett, Brian L., Coats, Caroline J., Hegde, Sheila M., Kulac, Ian J., Lee, Matthew M.Y., Maron, Martin S., Merkely, Bela, Michels, Michelle, Olivotto, Iacopo, Oreziak, Artur, Jacoby, Daniel L., Heitner, Stephen B., Kupfer, Stuart, Malik, Fady I., Meng, Lisa, Solomon, Scott D., Wohltman, Amy, Kwong, Raymond Y., and Kramer, Christopher M.

Published
2024
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4. Impact of Aficamten on Echocardiographic Cardiac Structure and Function in Symptomatic Obstructive Hypertrophic Cardiomyopathy

Author

Hegde, Sheila M., Claggett, Brian L., Wang, Xiaowen, Jering, Karola, Prasad, Narayana, Roshanali, Farideh, Masri, Ahmad, Nassif, Michael E., Barriales-Villa, Roberto, Abraham, Theodore P., Cardim, Nuno, Coats, Caroline J., Kramer, Christopher M., Maron, Martin S., Michels, Michelle, Olivotto, Iacopo, Saberi, Sara, Jacoby, Daniel L., Heitner, Stephen B., Kupfer, Stuart, Meng, Lisa, Wohltman, Amy, Malik, Fady I., and Solomon, Scott D.

Published
2024
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5. Efficacy and Safety of Aficamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy: Results From the REDWOOD-HCM Trial, Cohort 4

Author

MASRI, AHMAD, SHERRID, MARK V., ABRAHAM, THEODORE P., CHOUDHURY, LUBNA, GARCIA-PAVIA, PABLO, KRAMER, CHRISTOPHER M., BARRIALES-VILLA, ROBERTO, OWENS, ANJALI T., RADER, FLORIAN, NAGUEH, SHERIF F., OLIVOTTO, IACOPO, SABERI, SARA, TOWER-RADER, ALBREE, WONG, TIMOTHY C., COATS, CAROLINE J., WATKINS, HUGH, FIFER, MICHAEL A., SOLOMON, SCOTT D., HEITNER, STEPHEN B., JACOBY, DANIEL L., KUPFER, STUART, MALIK, FADY I., MENG, LISA, SOHN, REGINA L., WOHLTMAN, AMY, and MARON, MARTIN S.

Published
2024
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11. ACR Appropriateness Criteria® Sudden Onset of Cold, Painful Leg: 2023 Update

Author

Browne, William F., Sung, Jeffrey, Majdalany, Bill S., Khaja, Minhaj S., Calligaro, Keith, Contrella, Benjamin N., Ferencik, Maros, Gunn, Andrew J., Kapoor, Baljendra S., Keefe, Nicole A., Kokabi, Nima, Kramer, Christopher M., Kwun, Richard, Shamoun, Fadi, Sharma, Aditya M., Steenburg, Scott D., Trout, Andrew T., Vijay, Kanupriya, Wang, David S., and Steigner, Michael L.

Published
2023
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12. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

Author

Isselbacher, Eric M., Preventza, Ourania, Hamilton Black, James, III, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E., Brown-Zimmerman, Maya M., Chen, Edward P., Collins, Tyrone J., DeAnda, Abe, Jr., Fanola, Christina L., Girardi, Leonard N., Hicks, Caitlin W., Hui, Dawn S., Schuyler Jones, William, Kalahasti, Vidyasagar, Kim, Karen M., Milewicz, Dianna M., Oderich, Gustavo S., Ogbechie, Laura, Promes, Susan B., Ross, Elsie Gyang, Schermerhorn, Marc L., Singleton Times, Sabrina, Tseng, Elaine E., Wang, Grace J., Woo, Y. Joseph, Faxon, David P., Upchurch, Gilbert R., Jr, Aday, Aaron W., Azizzadeh, Ali, Boisen, Michael, Hawkins, Beau, Kramer, Christopher M., Luc, Jessica G.Y., MacGillivray, Thomas E., Malaisrie, S. Christopher, Osteen, Kathryn, Patel, Himanshu J., Patel, Parag J., Popescu, Wanda M., Rodriguez, Evelio, Sorber, Rebecca, Tsao, Philip S., Santos Volgman, Annabelle, Beckman, Joshua A., Otto, Catherine M., O'Gara, Patrick T., Armbruster, Anastasia, Birtcher, Kim K., de las Fuentes, Lisa, Deswal, Anita, Dixon, Dave L., Gorenek, Bulent, Haynes, Norrisa, Hernandez, Adrian F., Joglar, José A., Jones, W. Schuyler, Mark, Daniel, Mukherjee, Debabrata, Palaniappan, Latha, Piano, Mariann R., Rab, Tanveer, Spatz, Erica S., and Tamis-Holland, Jacqueline E.

Published
2023
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14. Cocoa to Improve Walking Performance in Older People With Peripheral Artery Disease: The Cocoa-Pad Pilot Randomized Clinical Trial

Author

McDermott, Mary M, Criqui, Michael H, Domanchuk, Kathryn, Ferrucci, Luigi, Guralnik, Jack M, Kibbe, Melina R, Kosmac, Kate, Kramer, Christopher M, Leeuwenburgh, Christiaan, Li, Lingyu, Lloyd-Jones, Donald, Peterson, Charlotte A, Polonsky, Tamar S, Stein, James H, Sufit, Robert, Van Horn, Linda, Villarreal, Francisco, Zhang, Dongxue, Zhao, Lihui, and Tian, Lu

Subjects
Clinical Trials and Supportive Activities, Complementary and Integrative Health, Prevention, Cardiovascular, Clinical Research, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Aged, Aged, 80 and over, Beverages, Catechin, Chocolate, Double-Blind Method, Electron Transport Complex IV, Female, Humans, Male, Muscle, Skeletal, Peripheral Arterial Disease, Regional Blood Flow, Walking, clinical trial, intermittent claudication, mitochondria, muscles, peripheral artery disease, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Cardiovascular System & Hematology
Abstract

RationaleCocoa and its major flavanol component, epicatechin, have therapeutic properties that may improve limb perfusion and increase calf muscle mitochondrial activity in people with lower extremity peripheral artery disease (PAD).ObjectiveIn a phase II randomized clinical trial, to assess whether 6 months of cocoa improved walking performance in people with PAD, compared with placebo.Methods and resultsSix-month double-blind, randomized clinical trial in which participants with PAD were randomized to either cocoa beverage versus placebo beverage. The cocoa beverage contained 15 g of cocoa and 75 mg of epicatechin daily. The identical appearing placebo contained neither cocoa nor epicatechin. The 2 primary outcomes were 6-month change in 6-minute walk distance measured 2.5 hours after a study beverage at 6-month follow-up and 24 hours after a study beverage at 6-month follow-up, respectively. A 1-sided P

Published
2020

15. 3-Dimensional Strain Analysis of Hypertrophic Cardiomyopathy: Insights From the NHLBI International HCM Registry

Author

Heydari, Bobak, Satriano, Alessandro, Jerosch-Herold, Michael, Kolm, Paul, Kim, Dong-Yun, Cheng, Kathleen, Choi, Yuna L., Antiochos, Panagiotis, White, James A., Mahmod, Masliza, Chan, Kenneth, Raman, Betty, Desai, Milind Y., Ho, Carolyn Y., Dolman, Sarahfaye F., Desvigne-Nickens, Patrice, Maron, Martin S., Friedrich, Matthias G., Schulz-Menger, Jeanette, Piechnik, Stefan K., Appelbaum, Evan, Weintraub, William S., Neubauer, Stefan, Kramer, Christopher M., and Kwong, Raymond Y.

Published
2023
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22. Machine learning for multidimensional response and survival after cardiac resynchronization therapy using features from cardiac magnetic resonance

Author

Bivona, Derek J., Tallavajhala, Srikar, Abdi, Mohamad, Oomen, Pim J.A., Gao, Xu, Malhotra, Rohit, Darby, Andrew E., Monfredi, Oliver J., Mangrum, J. Michael, Mason, Pamela K., Mazimba, Sula, Salerno, Michael, Kramer, Christopher M., Epstein, Frederick H., Holmes, Jeffrey W., and Bilchick, Kenneth C.

Published
2022
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25. Cardiovascular Magnetic Resonance for Patients With COVID-19

Author

Petersen, Steffen E., Friedrich, Matthias G., Leiner, Tim, Elias, Matthew D., Ferreira, Vanessa M., Fenski, Maximilian, Flamm, Scott D., Fogel, Mark, Garg, Ria, Halushka, Marc K., Hays, Allison G., Kawel-Boehm, Nadine, Kramer, Christopher M., Nagel, Eike, Ntusi, Ntobeko A.B., Ostenfeld, Ellen, Pennell, Dudley J., Raisi-Estabragh, Zahra, Reeder, Scott B., Rochitte, Carlos E., Starekova, Jitka, Suchá, Dominika, Tao, Qian, Schulz-Menger, Jeanette, and Bluemke, David A.

Published
2022
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26. Automatic Scar Segmentation from DE-MRI Using 2D Dilated UNet with Rotation-Based Augmentation

Author

Feng, Xue, Kramer, Christopher M., Salerno, Michael, Meyer, Craig H., Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Puyol Anton, Esther, editor, Pop, Mihaela, editor, Sermesant, Maxime, editor, Campello, Victor, editor, Lalande, Alain, editor, Lekadir, Karim, editor, Suinesiaputra, Avan, editor, Camara, Oscar, editor, and Young, Alistair, editor

Published
2021
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27. Society for Cardiovascular Magnetic Resonance (SCMR) guidelines for reporting cardiovascular magnetic resonance examinations

Author

Hundley, W. Gregory, Bluemke, David A., Bogaert, Jan, Flamm, Scott D., Fontana, Marianna, Friedrich, Matthias G., Grosse-Wortmann, Lars, Karamitsos, Theodoros D., Kramer, Christopher M., Kwong, Raymond Y., McConnell, Michael, Nagel, Eike, Neubauer, Stefan, Nijveldt, Robin, Pennell, Dudley J., Petersen, Steffen E., Raman, Subha V., and van Rossum, Albert

Published
2022
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30. Cardiac Magnetic Resonance Assessment of Response to Cardiac Resynchronization Therapy and Programming Strategies

Author

Gao, Xu, Abdi, Mohamad, Auger, Daniel A., Sun, Changyu, Hanson, Christopher A., Robinson, Austin A., Schumann, Christopher, Oomen, Pim J., Ratcliffe, Sarah, Malhotra, Rohit, Darby, Andrew, Monfredi, Oliver J., Mangrum, J. Michael, Mason, Pamela, Mazimba, Sula, Holmes, Jeffrey W., Kramer, Christopher M., Epstein, Frederick H., Salerno, Michael, and Bilchick, Kenneth C.

Published
2021
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31. Predictors of Major Atrial Fibrillation Endpoints in the National Heart, Lung, and Blood Institute HCMR

Author

Kramer, Christopher M., DiMarco, John P., Kolm, Paul, Ho, Carolyn Y., Desai, Milind Y., Kwong, Raymond Y., Dolman, Sarahfaye F., Desvigne-Nickens, Patrice, Geller, Nancy, Kim, Dong-Yun, Maron, Martin S., Appelbaum, Evan, Jerosch-Herold, Michael, Friedrich, Matthias G., Schulz-Menger, Jeanette, Piechnik, Stefan K., Mahmod, Masliza, Jacoby, Daniel, White, James, Chiribiri, Amedeo, Helms, Adam, Choudhury, Lubna, Michels, Michelle, Bradlow, William, Salerno, Michael, Dawson, Dana K., Weinsaft, Jonathan W., Berry, Colin, Nagueh, Sherif F., Buccarelli-Ducci, Chiara, Owens, Anjali, Casadei, Barbara, Watkins, Hugh, Weintraub, William S., and Neubauer, Stefan

Published
2021
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33. Quality assurance of quantitative cardiac T1-mapping in multicenter clinical trials – A T1 phantom program from the hypertrophic cardiomyopathy registry (HCMR) study

Author

Zhang, Qiang, Werys, Konrad, Popescu, Iulia A., Biasiolli, Luca, Ntusi, Ntobeko A.B., Desai, Milind, Zimmerman, Stefan L., Shah, Dipan J., Autry, Kyle, Kim, Bette, Kim, Han W., Jenista, Elizabeth R., Huber, Steffen, White, James A., McCann, Gerry P., Mohiddin, Saidi A., Boubertakh, Redha, Chiribiri, Amedeo, Newby, David, Prasad, Sanjay, Radjenovic, Aleksandra, Dawson, Dana, Schulz-Menger, Jeanette, Mahrholdt, Heiko, Carbone, Iacopo, Rimoldi, Ornella, Colagrande, Stefano, Calistri, Linda, Michels, Michelle, Hofman, Mark B.M., Anderson, Lisa, Broberg, Craig, Andrew, Flett, Sanz, Javier, Bucciarelli-Ducci, Chiara, Chow, Kelvin, Higgins, David, Broadbent, David A., Semple, Scott, Hafyane, Tarik, Wormleighton, Joanne, Salerno, Michael, He, Taigang, Plein, Sven, Kwong, Raymond Y., Jerosch-Herold, Michael, Kramer, Christopher M., Neubauer, Stefan, Ferreira, Vanessa M., and Piechnik, Stefan K.

Published
2021
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34. Femoral artery plaque characteristics, lower extremity collaterals, and mobility loss in peripheral artery disease

Author

McDermott, Mary M, Carroll, Timothy, Carr, James, Yuan, Chun, Ferrucci, Luigi, Guralnik, Jack M, Kibbe, Melina, Criqui, Michael H, Tian, Lu, Polonsky, Tamar, Zhao, Lihui, Gao, Ying, Hippe, Daniel S, Xu, Dongxiang, McCarthy, Walter, and Kramer, Christopher M

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Cardiovascular, Biomedical Imaging, Clinical Research, Aged, Aged, 80 and over, Ankle Brachial Index, Chicago, Collateral Circulation, Dependent Ambulation, Female, Femoral Artery, Humans, Lipids, Longitudinal Studies, Magnetic Resonance Angiography, Male, Mobility Limitation, Necrosis, Peripheral Arterial Disease, Plaque, Atherosclerotic, Predictive Value of Tests, Regional Blood Flow, Risk Factors, Time Factors, Vascular Calcification, Walk Test, atherosclerotic plaque, intermittent claudication, lipid rich necrotic core, mobility, peripheral artery disease, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

Little is known about the prognostic significance of specific characteristics of magnetic resonance imaging (MRI) measured plaque in the superficial femoral artery (SFA). Associations of MRI-measured plaque quantity, lumen area, and plaque composition in the SFA with subsequent mobility loss were studied in people with lower extremity peripheral artery disease (PAD). Participants with an ankle-brachial index (ABI) < 1.00 were identified from Chicago medical centers and underwent direct visualization of atherosclerotic plaque in the SFA using MRI. Participants were followed annually for up to 4 years. Mobility loss was defined as becoming unable to walk up and down a flight of stairs or walk one-quarter of a mile without assistance among participants without mobility impairment at baseline. Analyses adjusted for age, sex, race, comorbidities, ABI, physical activity, and other confounders. Of 308 PAD participants without baseline mobility impairment, 100 (32.5%) developed mobility loss during follow-up. Compared to the lowest mean plaque area tertile at baseline, participants in the highest (worst) plaque area tertile had a higher rate of mobility loss (hazard ratio (HR) = 2.08, 95% confidence interval (CI) = 1.14-3.79, p = 0.018). Compared to the highest mean lumen area tertile, the smallest (worst) mean lumen area tertile was associated with greater mobility loss (HR = 2.18, 95% CI = 1.20-3.96, p = 0.011). Neither lipid rich necrotic core nor calcium in the SFA were associated with mobility loss. In conclusion, greater plaque quantity and smaller lumen area in the proximal SFA, but not lipid rich necrotic core or calcium, were associated with higher mobility loss in people with PAD.

Published
2017

35. Plaque Composition in the Proximal Superficial Femoral Artery and Peripheral Artery Disease Events

Author

McDermott, Mary M, Kramer, Christopher M, Tian, Lu, Carr, James, Guralnik, Jack M, Polonsky, Tamar, Carroll, Timothy, Kibbe, Melina, Criqui, Michael H, Ferrucci, Luigi, Zhao, Lihui, Hippe, Daniel S, Wilkins, John, Xu, Dongxiang, Liao, Yihua, McCarthy, Walter, and Yuan, Chun

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Stroke, Atherosclerosis, Heart Disease, Cardiovascular, Clinical Research, Good Health and Well Being, Acute Coronary Syndrome, Aged, Amputation, Surgical, Ankle Brachial Index, Chicago, Comorbidity, Critical Illness, Female, Femoral Artery, Fibrosis, Humans, Ischemia, Kaplan-Meier Estimate, Lipids, Longitudinal Studies, Magnetic Resonance Angiography, Male, Middle Aged, Peripheral Arterial Disease, Plaque, Atherosclerotic, Predictive Value of Tests, Proportional Hazards Models, Risk Factors, Time Factors, Treatment Outcome, Vascular Calcification, Vascular Surgical Procedures, femoral artery, lipid rich, necrotic core, MRI, vascular medicine, lipid rich necrotic core, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

ObjectivesThe aim of this study was to describe associations of the presence of lipid-rich necrotic core (LRNC) in the proximal superficial femoral artery (SFA) with lower extremity peripheral artery disease (PAD) event rates and systemic cardiovascular event rates.BackgroundLRNC in the coronary and carotid arteries is associated with adverse outcomes but has not been studied previously in lower extremity arteries.MethodsParticipants with ankle-brachial index (ABI) values 0.15, and revascularization at 47-month follow-up (hazard ratio: 2.18; 95% confidence interval: 1.27 to 3.75; p = 0.005). The association of SFA LRNC with PAD events was maintained even when this combined outcome excluded lower extremity revascularization (hazard ratio: 2.58; 95% confidence interval: 1.25 to 5.33; p = 0.01). LRNC in the SFA was not associated with all-cause mortality, acute coronary events, or stroke.ConclusionsAmong patients with PAD, LRNC in the SFA was associated with higher rates of clinical PAD events, and this association was independent of ABI. Further study is needed to determine whether interventions that reduce SFA LRNC prevent PAD events.

Published
2017

36. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

Author

Isselbacher, Eric M., Preventza, Ourania, Hamilton Black, James, III, Augoustides, John G., Beck, Adam W., Bolen, Michael A., Braverman, Alan C., Bray, Bruce E., Brown-Zimmerman, Maya M., Chen, Edward P., Collins, Tyrone J., DeAnda, Abe, Jr, Fanola, Christina L., Girardi, Leonard N., Hicks, Caitlin W., Hui, Dawn S., Schuyler Jones, William, Kalahasti, Vidyasagar, Kim, Karen M., Milewicz, Dianna M., Oderich, Gustavo S., Ogbechie, Laura, Promes, Susan B., Gyang Ross, Elsie, Schermerhorn, Marc L., Singleton Times, Sabrina, Tseng, Elaine E., Wang, Grace J., Woo, Y. Joseph, Faxon, David P., Upchurch, Gilbert R., Jr, Aday, Aaron W., Azizzadeh, Ali, Boisen, Michael, Hawkins, Beau, Kramer, Christopher M., Luc, Jessica G.Y., MacGillivray, Thomas E., Malaisrie, S. Christopher, Osteen, Kathryn, Patel, Himanshu J., Patel, Parag J., Popescu, Wanda M., Rodriguez, Evelio, Sorber, Rebecca, Tsao, Philip S., and Santos Volgman, Annabelle

Published
2022
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40. Recommendations on the Use of Multimodality Cardiovascular Imaging in Young Adult Competitive Athletes: A Report from the American Society of Echocardiography in Collaboration with the Society of Cardiovascular Computed Tomography and the Society for Cardiovascular Magnetic Resonance

Author

Baggish, Aaron L., Battle, Robert W., Beaver, Timothy A., Border, William L., Douglas, Pamela S., Kramer, Christopher M., Martinez, Matthew W., Mercandetti, Jennifer H., Phelan, Dermot, Singh, Tamanna K., Weiner, Rory B., and Williamson, Eric

Published
2020
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43. Cardiometabolic biomarker patterns associated with cardiac MRI defined fibrosis and microvascular dysfunction in patients with heart failure with preserved ejection fraction

Author

Siggins, Connor, primary, Pan, Jonathan A., additional, Löffler, Adrián I., additional, Yang, Yang, additional, Shaw, Peter W., additional, Balfour, Pelbreton C., additional, Epstein, Frederick H., additional, Gan, Li-Ming, additional, Kramer, Christopher M., additional, Keeley, Ellen C., additional, and Salerno, Michael, additional

Published
2024
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44. Pilot Study of Supervised Exercise and Intensive Medical Therapy in Patients With Ischemia With No Evidence of Obstructive Coronary Artery Disease and Coronary Microvascular Dysfunction

Author

Schumann, Christopher L., primary, Nealy, Zachariah B., additional, Mathew, Roshin C., additional, Yang, Yang, additional, Balfour, Pelbreton C., additional, Shaw, Peter W., additional, Salerno, Michael, additional, Kramer, Christopher M., additional, and Bourque, Jamieson M., additional

Published
2024
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45. A Multicenter Evaluation of the Impact of Therapies on Deep Learning-based Electrocardiographic Hypertrophic Cardiomyopathy Markers

Author

Dhingra, Lovedeep S, primary, Sangha, Veer, additional, Aminorroaya, Arya, additional, Bryde, Robyn, additional, Gaballa, Andrew, additional, Ali, Adel H, additional, Mehra, Nandini, additional, Krumholz, Harlan M., additional, Sen, Sounok, additional, Kramer, Christopher M, additional, Martinez, Matthew W, additional, Desai, Milind Y, additional, Oikonomou, Evangelos K, additional, and Khera, Rohan, additional

Published
2024
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