Search

Problem: Physical exercises (PE) have positive effects on health related quality of life (HQoL) and chronic non-communicable diseases (NCD). This survey assessed the extent of the Covid-19 induced lockdown on changes of PE and HQoL of study patients with at least two chronic NCD.Methods: An online survey, including the Veterans Rand 12 (subscales general health (GH), physical (PCS), mental (MCS) component scales) and questions on lockdown-induced PE habit changes was hold. HQoL was assessed prior, during and after the lockdown. Also, the usage of digital training videos was assessed. Kruskal-Wallis-Tests and post-hoc analysis evaluated if HQoL differed between categories of PE changes during the lockdown (less, same, more). Results: 27 (18 females, mean age: 54.6 11.4) completed the survey. 37% stated less or no PE, 22% more PE. Especially strength training was affected with 72% of the responders performing less strength training during lock down. MCS and PCS differed not significantly according to PE change, but better GH was associated with increased PE in comparison to less/no PE (z=-2.5, p=0.04, r=0.6). Discussion: Participants who increased PE during the lockdown showed better GH scores, highlighting the importance to maintain PE. Permission to continue sports in nature is recommended in similar situations. Digital media such as training videos designed to fulfill the needs of people with NCD have to be created, so that people can continue strength training.Trial registration: The study was registered in the German clinical trial register (DRKS00016702).Key Words: Sport, Pandemic, Multimorbidity, Health Related Quality of Life, Non-Communicable Chronic Conditions, Germany

Osteoarthritis (OA) is a pro-infl ammatory, degenerative disease of the joints. Since the osteoarthritis risk pro le overlaps with that of other lifestyle-related diseases, such as obesity, type 2 diabetes mellitus (T2DM), or cardiovascular disease, a ected individuals are often multi-morbid. Physical activity has been demonstrated to be a valuable preventive and therapeutic tool in OA and also in almost all other lifestyle-related diseases. us, a ected individuals might bene t from an exercise program in multiple respects. To monitor e cacy of such training interventions, a set of reliable biomarkers, preferentially such that can be assessed from easily accessible biological uids, in particular urine or blood, would be desirable.In this short review, we give an overview of potential blood and urine biomarkers that might be used to monitor e cacy of exercise interventions in osteoarthritis patients, with a speci c focus on multi-morbidity. Currently, the most-extensively studied markers are in ammation-related factors, such as C-reactive protein (CRP) or interleukin-6 (IL-6), but also metabolic markers, for example the adipokines adiponectin, leptin, and resistin, and products of cartilage decay, such as C-telopeptide of type II collagen (CTX-II), or cartilage oligomeric protein (COMP). Finally, recent studies also point to circulating microRNAs (miRNAs) as potential biomarkers in OA, suggesting that they might also have the potential to be studied in the context of training interventions. KEY WORDS: Degenerative Joint Disease, Lifestyle-Related Diseases, Physical Activity, Blood and Urine Markers

Copyright of German Journal of Sports Medicine / Deutsche Zeitschrift fur Sportmedizin is the property of Verein zur Forderung der Sportmedizin Hannover e.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)