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Acknowledgements This study contracted ICES Data & Analytic Services and used de-identified data from the ICES Data Repository, which is managed by ICES with support from its funders and partners: Canada's Strategy for Patient-Oriented Research (SPOR), the Ontario SPOR Support Unit, the Canadian Institutes of Health Research and the Government of Ontario. Baseline data include personal and family health history; socio-demographic information; personal exposures to tobacco, alcohol and medications; and detailed information on ethnicity and country of origin (Box 1 and Table 2). The linking of Canada's rich collection of administrative health data with the cohort's data represents a powerful means to disseminate high-quality, timely data. The OHS does not hold administrative health data or cancer registry data. [Extracted from the article]

The Population Studies Research Network of Cancer Care Ontario hosted a strategic planning workshop to establish an agenda for a prevention intervention research program in Ontario, including priority topics for investigation and design considerations. The two-day workshop included: presentations on background papers developed to facilitate participants' preparation for and discussions in the workshop; keynote presentations on intervention research concerning primary prevention of chronic diseases, design and study implementation considerations; a dedicated session on critical and creative thinking to stimulate participation and discussion topics; breakout groups to identify, discuss and present study ideas, designs, implementation considerations; and a consensus process to discuss and identify recommendations for research priorities and next steps. The retreat yielded the following recommendations: 1) develop an intervention research agenda that includes working with existing large-scale cohorts; 2) develop an intervention research agenda that includes novel research designs that could target individuals or groups; and 3) develop an intervention research agenda in which studies collect data on costs, define stakeholders, and ensure clear strategies for stakeholder engagement and knowledge transfer. The Population Studies Research Network will develop options from these recommendations and release a call for proposals in 2014 for intervention research pilot projects that reflect these recommendations. Pilot projects will be evaluated based on their fit with the retreat's recommendations, and their potential to scale up to full studies and application in practice. KEY WORDS: Research design; cohort studies; intervention studies; randomized controlled trials; prevention and control La traduction du resume se trouve a la fin de l'article. Can j Public Health 2014; 105(2):e150-e153. Le reseau de recherche ' Etude de la population ' d'Action Cancer Ontario a organise un atelier de planification strategique afin de fixer l'agenda d'un programme de recherche d'intervention sur la prevention en Ontario, y compris les themes prioritaires a aborder et les elements a considerer dans le plan d'etude. L'atelier de deux jours incluait : des presentations sur les documents de base elabores pour faciliter la preparation des participants et leurs discussions durant l'atelier; des allocutions sur la recherche d'intervention axee sur la prevention primaire des maladies chroniques, le plan d'etude et les elements a considerer dans la mise en oeuvre de l'etude; une seance consacree a la pensee critique et creatrice pour stimuler la participation et les sujets de discussion; la formation de petits groupes pour cerner, discuter et presenter des idees d'etude, des plans d'etude et des elements a considerer pour la mise en oeuvre; et un exercice de consensus pour discuter des priorites de recherche et de la suite des choses et formuler des recommandations. Ces journees de reflexion ont produit les recommandations suivantes : 1) elaborer un agenda pour la recherche d'intervention incluant l'utilisation des cohortes a grande echelle existantes; 2) elaborer un agenda pour la recherche d'intervention incluant des plans de recherche novateurs qui pourraient cibler des particuliers ou des groupes; et 3) elaborer un agenda pour la recherche d'intervention avec des etudes pour recueillir des donnees sur les couts, identifier les acteurs du milieu et presenter des strategies claires pour la mobilisation des acteurs et le transfert des connaissances. Le reseau de recherche ' Etude de la population ' formulera des options a partir de ces recommandations et lancera un appel de propositions en 2014 pour des projets-pilotes de recherche d'intervention qui refletent ces recommandations. Les projets-pilotes seront evalues selon leur degre de correspondance avec les recommandations de l'atelier, leur potentiel de transformation en etudes completes et leurs possibilites de mise en pratique. MOTS CLES : plan de recherche; etudes de cohortes; etudes d'intervention; essais comparatifs randomises; prevention et controle, Canada's population is aging. About half of Canadian seniors report one or two chronic diseases and 24% have three or more long-term co-morbidities. (1) The coexistence of multiple chronic diseases [...]

Substantial evidence suggests that soy isoflavones may protect against certain chronic diseases. This study aims to assess the reproducibility and validity of a 47-item semiquantitative soy FFQ (SFFQ) designed to measure the usual intake of soy isoflavones among 145 Chinese mid-life women in Hong Kong. Reproducibility of the SFFQ was assessed by the stability of dietary intake obtained at baseline ([SFFQ.sub.0]) and at 13-mo follow-up ([SFFQ.sub.1]). Relative validity was measured by comparing data collected from [SFFQ.sub.1] with those derived from 23-d, 24-h dietary recalls (DR) collected during the same 1-y validation period. Isoflavone intake was calculated using analytical values from the Chinese University of Hong Kong Soy Isoflavone Database. A total of 3,217 DR were successfully obtained. The median (interquartile range) absolute intake estimated by the [SFFQ.sub.1 was 0.91 (-2.7 to 6.8) mg aglucon equivalents/d higher than the 6.3 (3.7-10.7) mg aglucon equivalents/d measured by the DR (P < 0.0057; Wilcoxon's Signed Rank test). Bland-Altman analysis further demonstrated the presence of significant proportional bias between methods among Cantonese women with above-median intake (Spearman correlation coefficient; r = 0.44; P- 0.0005). Nonetheless, the intraclass and Pearson correlation coefficients, respectively, were 0.84 and 0.72 for non-Cantonese and 0.65 and 0.50 for Cantonese, showing moderate to good levels of reproducibility and validity of the SFFQ (difference between 2 intraclass correlation coefficients, P = 0.09; difference between 2 Pearson r, P = 0.16). The unadjusted and BMI-adjusted correlations were of similar magnitude. The SFFQ is a reasonably valid instrument for assessing dietary soy isoflavone exposure in Hong Kong Chinese mid-life women.

The dietary sources, intake levels, and determinants of soy isoflavone intake were examined using 3217 dietary recalls (DR) collected from 141 Hong Kong Chinese women aged 50-61 y. Multiple-pass 24-h DR were administered by phone by trained interviewers on 23 random, nonconsecutive days to participants over a 12-mo period from 2001 to 2002. We calculated isoflavone intake using analytical values in the Chinese University of Hong Kong Soy Isoflavone Database. Results indicated that the daily intake of total isoflavones was 7.8 [+ or -] 5.6 mg in the study population. Non- Cantonese women had a higher intake of 10.7 [+ or -] 7.6 mg compared with 7.3 [+ or -] 5.0 mg in Cantonese women (P=0.04). Altogether, 22 foods contributed ~90% of the total isoflavone intake. Soft tofu alone accounted for ~21% of the isoflavone intake, followed by bean curd skin (7.1%), name-brand soybean milk (6.3%), homemade soybean milk (6.2%), and generic soybean milk (5.8%). Combined, these ,5 food items contributed 46% of the total dietary isoflavones. Multiple linear regression analysis indicated dialect group, self-reported health, and age group were significant independent predictors of soy isoflavone consumption. The data provide the basis for elucidating the patterns, determinants, and assessment of dietary soy isoflavone intake in Asian women.