Search

Your search keyword '"Krejović-Trivić Sanja"' showing total 15 results
Start Over Author "Krejović-Trivić Sanja"
15 results on '"Krejović-Trivić Sanja"'

1. p16 status of oropharyngeal and oral cavity squamous cell carcinomas: A single institution experience

Author

Tomanović Nada, Tomić Anamarija, Boričić Ivan, Milovanović Jovica, Folić Miljan, Krejović-Trivić Sanja, Miković Nikola, Đorić Igor, Parapid Biljana, Uskoković Nikola, and Trivić Aleksandar

Subjects
oropharynx, oral cavity, human papilloma virus, squamous cell carcinoma, Medicine
Abstract

Introduction/Objective. New World Health Organization Classification of Head and Neck Tumors from 2017 has introduced significant changes, mainly considering tumors in the oropharyngeal region. New entities of HPV-positive and -negative squamous cell carcinomas have been acknowledged, not only based on the presence of an active viral infection and different tumor markers expression, but also because of their different histopathology, staging assessment, and prognosis. A retrospective study has been conducted, in order to determine p16 positivity in squamous cell carcinomas in oropharynx and in the oral cavity, and to see whether they differ in sex and age distribution. Methods. The presence of viral infection was verified based on p16 immunochemistry staining, p16 being the surrogate marker for HPV infection. A total of 177 cases of squamous cell carcinomas in the oropharynx and the oral cavity, found in the archives of the Histopathology Laboratory of the Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, have been revised. Results. Out of 177 cases, 50 (28.2%) were p16-positive. Compared with carcinomas in the oral cavity, p16 carcinomas were significantly more common in the oropharynx (34.3% in the oropharynx, compared to 10.3% in the oral cavity). Carcinomas in both regions were mostly associated with male sex (88.1% of all cases were in males), but p16 positivity was more common in females (11 out of 21 cases, 52.4%). The most common location of p16-positive carcinomas were palatine tonsils (41.03% of tonsillar carcinomas were p16-positive). Conclusion. P16-positive squamous cell carcinomas were the most numerous in the oropharynx, i.e. palatine tonsils, and were more common in females.

Published
2020
Full Text
View/download PDF

2. Survival outcomes in surgically treated patients with advanced laryngeal cancer in Serbia

Author

Milovanović Jovica, Jotić Ana, Tešić-Vidović Ljiljana, Đukić Vojko, Trivić Aleksandar, Krejović-Trivić Sanja, Radin Zorana, Savić-Vujović Katarina, Milovanović Anđela, Banko Bojan, and Artiko Vera

Subjects
laryngeal neoplasms, postoperative period, survival, risk factors, neoplasm staging, Medicine (General), R5-920
Abstract

Background/Aim. Laryngeal carcinomas make 1%–3% of all head and neck malignancies.Treatment outcome and survival rates depend greatly on established stage of the disease. The purpose of this study was to examine the survival of the patients with advanced laryngeal carcinoma depending on gender, age, common risk factors (tobacco and alcohol use), primary tumor localization, histopathological tumor grade, clinical TNM (tumor, node and metastasis) stage and surgical treatment of the disease. Methods. Retrospective study included 252 patients treated surgically for advanced squamocellular carcinoma of the larynx in a threeyear period with five-year follow-up. Patients included in the study were treated primary with surgery, with postoperative radiotherapy and chemotherapy depending on the stage of the disease, intraoperative findings and tumor resection borders. Overall survival and disease-specific five-year survival of patients was calculated for demographical and clinical characteristics of the patients. Results. Overall 5-year survival of patients with operable advanced laryngeal cancer included in the study was 86.14% and disease-specific survival 86.51%. Lower overall and the disease-specific survival was associated with age, higher histological tumor grade and more extensive neck dissections. Conclusion. Primary total laryngectomy results in higher survival outcomes in cases of transglottic T3 and T4a laryngeal tumors. Patients should be informed of the likely increased mortality risks tied to the choice of surgical resection and treatment modality before their decision.

Published
2020
Full Text
View/download PDF

3. Nasal polyposis: A semiquantitative morphometric histopathological study

Author

Trivić Aleksandar, Tomanović Nada, Krejović-Trivić Sanja, Milovanović Jovica, Boričić Ivan, Jotić Ana, Folić Miljan, Ćolović-Čalovski Ivana, Miković Nikola, and Tatić Zoran

Subjects
nasal polyps, otorhinolaryngologic surgical procedures, postoperative complications, histology, Medicine (General), R5-920
Abstract

Background/Aim. Nasal polyps are inflammatory hyper-trophic proliferations of the sinonasal mucosa composed of both epithelial and stromal elements. The aim of this study was to determine histopathological hallmarks of nasal polyposis via semiquantitative morphometric study. Methods. The study comprised 77 patients with chronic rhinosinusitis and nasal polyposis (CRSwNP) that underwent functional endoscopic sinonasal surgery performed by the same surgeon. The control group consisted of 9 different nasal mucosal samples that were taken from patients without CRSwNP that underwent functional and esthetic surgery. Morphometric analysis included gradation of tissue edema within polyps, thickening of epithelial basal membrane, degree of inflammation, presence/absence of metaplasia with-in epithelium, degree of fibrosis within polyps, and percentage of inflammatory cells within inflammatory infiltrate (lymphocytes, macrophages, plasma cells, neutrophils and eosinophils). Results. As expected, samples from the study group showed significantly higher degree of inflammation than samples from the control group (χ2 = 35.89, with p < 0.01). Degree of fibrosis in nasal polyposis was in positive correlation with duration of symptoms (r = 0.25, p < 0.05) and with percentage of macrophages in inflammatory infiltrate (r = 0.26, p < 0.05). Patients with nasal polyposis had significantly lower number of lymphocytes (r = -7.66, p < 0.01), but significantly higher number of eosinophils (r = 3.84, p < 0.01), macrophages (r = 3.34, p < 0.01) and plasma cells (r = 3.14, p < 0.01) than controls (p < 0.01). Conclusion. Tissue samples from patients with nasal polyposis show significant changes that reflect in various degrees of inflammation, fibrosis and basement membrane thickening which may contribute to more difficult surgical management and perioperative complications such as bleeding.

Published
2020
Full Text
View/download PDF

4. Quality of life of laryngectomized patients in Serbia

Author

Krejović-Trivić Sanja, Milovanović Jovica, Parapid Biljana, Vukašinović Milan, Miković Nikola, and Trivić Aleksandar

Subjects
quality of life, total laryngectomy, esophageal voice and speech, phoniatric rehabilitation, Medicine
Abstract

Introduction/Objective. Total laryngectomy is a very mutilating operation and it leads to drastic changes in life quality. The purpose of this study was to examine factors of importance to the laryngectomized patients’ quality of life and to evaluate characteristics of esophageal voice and speech. Methods. The study was conducted at the Clinic of Otorhinolaryngology and Maxillofacial Surgery, at the Clinical Center of Serbia (Belgrade, Serbia), during the period between March 2012–2015. The study included 223 patients diagnosed with laryngeal cancer, who underwent total laryngectomy. The total of 168 laryngectomized patients were provided with phoniatric rehabilitation. Results. The quality of life was significantly better for those laryngectomized patients who did undergo phoniatric rehabilitation. By means of intensive phoniatric rehabilitation the esophageal voice and speech was established in 86.3% of laryngectomized patients registered by objective acoustic analysis. Rehabilitated laryngectomy patients had a significantly lower presence of voice handicap sense (VHI: 19.57 Ѓ} 7.35) and expressed significantly lower symptoms of depression and anxiety (PHQ-9: 3.8 Ѓ} 4.2; GAD-7: 3.4 Ѓ} 4.2). Cronbach’s alpha coefficient was above 0.7 EORTC QLQ-C30 on three levels of Likert scales: the scale of physical and emotional functioning and fatigue; as well as EORTC QLQ-H&N43 questionnaire: the symptoms of head and neck pain, speech, swallowing and eating problems and body image. Conclusion. Significantly improving the quality of life of laryngectomized patients was achieved by a multidisciplinary rehabilitation. Phoniatric rehabilitation carried out in a planned and systematic way is the most efficient rehabilitation of laryngectomized patients.

Published
2018
Full Text
View/download PDF

5. Radiographic cephalometry analysis of condylar position after bimaxillary osteotomy in patients with mandibular prognathism

Author

Miković Nikola D., Lazarević Miloš M., Tatić Zoran, Krejović-Trivić Sanja, Petrović Milan, and Trivić Aleksandar

Subjects
prognathism, surgery, oral, postoperative period, cephalometry, temporomandibular joint, centric relation, Medicine (General), R5-920
Abstract

Background/Aim. Postoperative condylar position is a substantial concern in surgical correction of mandibular prognathism. Orthognathic surgery may change condylar position and this is considered a contributing factor for early skeletal relapse and the induction of temporomandibular disorders. The purpose of this study was to evaluate changes in condylar position, and to correlate angular skeletal measurements following bimaxillary surgery. Methods. On profile teleradiographs of 21 patients with mandibular angular and linear parametres, the changes in condylar position, were measured during preoperative orthodontic treatment and 6 months after the surgical treatment. Results. A statistically significant difference in values between the groups was found. The most distal point on the head of condyle point (DI) moved backward for 1.38 mm (p = 0.02), and the point of center of collum mandibulae point (DC) moved backward for 1.52 mm (p = 0.007). The amount of upward movement of the point DI was 1.62 mm (p = 0.04). Conclusion. In the patients with mandibular prognathism, the condyles tend to migrate upward and forward six months after bimaxillary surgery.

Published
2016
Full Text
View/download PDF

6. Laryngeal granuloma: Benefit in treatment with zinc supplementation?

Author

Đukić Vojko, Krejović-Trivić Sanja, Vukašinović Milan, Trivić Aleksandar, Pavlović Bojan, Milovanović Aleksandar, and Milovanović Jovica

Subjects
conservative treatment, laryngeal granuloma, zinc supplementation, Biochemistry, QD415-436
Abstract

Laryngeal granulomas present as contact and postintubation ulcers and granulomas. Essentially, a contact granuloma is a pseudotumor of the lateral wall of the posterior glottis. The most common etiological factor is voice abuse, with predisponing factors such as reflux disease. Postintubation ulcers and granulomas, although of different etiology, according to all the other traits belong to this clinical entity. The therapy of choice is conservative treatment. Surgical laser excision is indicated for resistant cases and those whose size is causing respiratory distress. Treatment of laryngeal granulomas with zinc supplementation is reported in the literature as one of the forms of conservative treatment, and we wanted to consider it in this review. Zinc is an essential mineral that plays a vital role in many biochemical reactions and is considered very important for wound healing.

Published
2015

7. The european organisation for research and treatment of cancer head and neck cancer module (EORTC QLQ-HN43): Estimates for minimal important difference and minimal important change

Author

Singer, Susanne, Hammerlid, Eva, Tomaszewska, Iwona M., Amdal, Cecilie D., Herlofson, Bente B., Santos, Marcos, Castro Silva, Joaquim, Mehanna, Hisham, Fullerton, Amy, Young, Teresa, Fernandez Gonzalez, Loreto, Inhestern, Johanna, Pinto, Monica, Arraras, Juan I., Yarom, Noam, Bonomo, Pierluigi, Baumann, Ingo, Galalae, Razvan, Nicolatou-Galitis, Ourania, Kiyota, Naomi, Raber-Durlacher, Judith, Salem, Dina, Fabian, Alexander, Boehm, Andreas, Krejovic-Trivic, Sanja, Chie, Wei-Chu, Taylor, Katherine J., Sherman, Allen C., Licitra, Lisa, Machiels, Jean-Pascal, and Bjordal, Kristin

Published
2024
Full Text
View/download PDF

8. Faktori rizika, prognostički faktori i kvalitet života u obolelih od malignih tumora usne šupljine i ždrela

Author

Milovanović, Jovica, Đukić, Vojko, Krejović-Trivić, Sanja, Kosanović, Rade, Andrejić, Dragoslava M., Milovanović, Jovica, Đukić, Vojko, Krejović-Trivić, Sanja, Kosanović, Rade, and Andrejić, Dragoslava M.

Abstract

aligni tumori predstavljaju značajan medicinski problem i imaju veliki socijalno-ekonomski značaj. Česta su oboljenja u svim delovima sveta i zabrinjavajuća je sve veća učestalost malignih tumora i pomeranje starosne granice ka mlađim populacionim grupama. Među uzrocima smrtnosti nalaze se u svetu i kod nas na drugom mestu posle oboljenja kardiovaskularnog sistema. Značajna nova otkrića u oblasti dijagnostike i terapije su dovela do bitnog povećanja dužine preživljavanja obolelih što je aktuelizovalo pitanje kvaliteta života obolelih. Lečenje obolelih od malignih tumora usne šupljine i ždrela je složen medicinski i psihosociološki problem, zato što su operacije ovih tumora mutilantne i bitno menjaju način i kvalitet života; bolest kao takva uslovljava smanjenje radne sposobnosti, a nakon lečenja je neophodna kompletna psihološko-socijalna i fonijatrijska rehabilitacija. U cilju podizanja kvaliteta života obolelih i lečenih od malignih tumora usne šupljine i ždrela potrebna je sistematska, multidisciplinarna rehabilitacija bolesnika i edukativna adaptacija njegove okoline. Ispitivanje faktora rizika za nastajanje ovih malignih tumora omogućava nova saznanja koja se koriste pre svega u prevenciji bolesti. Praćenje dužine preživljavanja daje smernice u planiranju terapijskih modaliteta. Cilj rada je bio da se analizira kretanje obolevanja i umiranja od malignih tumora usne šupljine i ždrela tokom trinaest godina na području centralne Srbije; da se ispita kvalitet života obolelih od ovih malignih tumora u odnosu na demografske karakteristike, težinu kliničke slike i psihosocijalne parametre; da se identifikuju potencijalni faktori rizika za nastanak malignih tumora usne šupljine i ždrela i da se analizira trogodišnje preživljavanje obolelih. Metod. Analiza obolevanja od malignih tumora usne šupljine i ždrela je vršena korišćenjem podataka Instituta za javno zdravlje Srbije ,, Dr Milan Jovanović –Batut“ u Beogradu, a podaci o umrlima su dobijeni iz nepublikovanog materij, Introduction. Malignant tumours represent a significant medical problem, with a considerable socio-economic impact. The disease is common in all parts of the world, with a worrying tendency of prevalence of malignant tumours and lowering of the age limit to include younger population groups. It is the second leading cause of death, both globally and in our country, after cardiovascular disease. Major new diagnostic and therapeutic discoveries resulted in a significantly enhanced length of survival for patients, which brought to the fore quality of life issues for patients. The treatment of patients with malignant tumours of the oral cavity and pharynx is a complex medical and psycho-social problem, as surgical treatment of these tumours tends to cause disfiguring and significantly alters the way and quality of life; the disease in itself causes reduced working abilities, and a full psycho-social and phoniatric rehabilitation is required once treatment is completed. Improving the quality of life of diseased and treated patients with malignant tumours of the oral cavity and pharynx requires systematic, multi-disciplinary rehabilitation of patient and an educational adaptation of his/her environment. Research into risk factors for the development of these malignant tumours provides new insights which are primarily used in prevention of disease. Monitoring of the length of survival provides guidelines for planning treatment modalities. The goal of this paper was to analyse incidence and mortality rates for malignant tumours of the oral cavity and pharynx over the thirteen years in central Serbia; to investigate the quality of life of patients with this type of malignant tumour in relation to demographic characteristics, severity of clinical presentation and psycho-social parameters. To identify potential risk factors for developing malignant tumours of the oral cavity and pharynx and to analyse a three-year survival period of patients...

Published
2018

9. Rendgen-kefalometrijska analiza pozicije kondila nakon bimaksilarne osteotomije mandibularnog prognatizma

Author

Miković, Nikola, Lazarević, Miloš, Tatić, Zoran, Krejović-Trivić, Sanja, Petrović, Milan, and Trivić, Aleksandar

Subjects
maksilofacijalna, postoperativni period, temporomandibularni zglob, centrički odnos, postoperative period, centric relation, kefalometrija, surgery, oral, stomatognathic system, cephalometry, temporomandibular joint, prognathism, prognatizam, hirurgija
Abstract

Background/Aim. Postoperative condylar position is a substantial concern in surgical correction of mandibular prognathism. Orthognathic surgery may change condylar position and this is considered a contributing factor for early skeletal relapse and the induction of temporomandibular disorders. The purpose of this study was to evaluate changes in condylar position, and to correlate angular skeletal measurements following bimaxillary surgery. Methods. On profile teleradiographs of 21 patients with mandibular angular and linear parametres, the changes in condylar position, were measured during preoperative orthodontic treatment and 6 months after the surgical treatment. Results. A statistically significant difference in values between the groups was found. The most distal point on the head of condyle point (DI) moved backward for 1.38 mm (p = 0.02), and the point of center of collum mandibulae point (DC) moved backward for 1.52 mm (p = 0.007). The amount of upward movement of the point DI was 1.62 mm (p = 0.04). Conclusion. In the patients with mandibular prognathism, the condyles tend to migrate upward and forward six months after bimaxillary surgery., Uvod/Cilj. Postoperativna pozicija kondila je značajna za hiruršku korekciju mandibularnog prognatizma. Ortognatska hirurgija može da promeni poziciju kondila, a to može biti jedan od faktora koji doprinosi ranom skeletnom recidivu i pojavi temporomandibularnih disfunkcija. Zbog toga je cilj ove studije bio da proceni promene pozicije kondila kao i da ne korelišu promene pozicije kondila sa angularnim skeletnim promenama nakon bimaksilarne hirurgije. Metode. Na telerendgenskim snimcima 21 bolesnika sa mandibularnim prognatizmom mereni su angularni i linearni parametri koji opisuju promene u položaju kondila, pre ortodontske pripreme i šest meseci nakon hirurške korekcije. Rezultati. Ustanovljena je statistička značajnost razlika u vrednosti parametara između grupa. Tačka DI - najdistalnija tačka na glavi kondila, pomerila se unazad 1,38 mm (p = 0,02), a tačka DC - tačka koja označava centar collum mandibulae, pomerila se, takođe, unazad za 1,52 mm (p = 0,007). Vrednost pomeranja tačke DI naviše bila je 1,62 mm (p = 0,04). Zaključak. Kod bolesnika sa mandibularnim prognatizmom, kondili su težili da migriraju unapred i naviše šest meseci nakon bimaksilarne operacije.

Published
2016

10. Evaluacija parametara od značaja za kvalitet života laringektomisanih bolesnika

Author

Krejović Trivić, Sanja B., Stanković, Predrag, Arsović, Nenad, Đorđević, Vladimir, and Mitrović, Slobodan

Subjects
Kvalitet života, Quality of life, totalna laringektomija, ezofagusni glas i govor, EORTC QLQ-C30 and QLQ-H & N43, EORTC QLQ-C30 i QLQ-H&N43, karcinom larinksa, laryngeal cancer, esophageal voice and speech, total laryngectomy, fonijatrijska rehabilitacija, foniatric rehabilitation
Abstract

Uvod:Kvalitet života trenutno predstavlja najaktuelniji koncept savremene nauke i smatra se idealom moderne medicine. Holistički pristup lečenju čoveka a ne samo bolesti igra značajnu ulogu u ostvarenju koncepta kvaliteta života povezanog sa zdravljem. Kvalitetu života laringektomisanih bolesnika u našoj sredini nije posvećena adekvatna pažnja. Totalna laringektomija kao veoma mutilantna operacija dovodi do drastičnih promena u kvalitetu života. Multidisciplinarni rehabilitacioni program je neophodan laringektomisanim bolesnicima da bi poboljšali kvalitet života. Fonijatrijska rehabilitacija je najznačajniji vid rehabilitacije jer omogućava uspostavljanje verbalne komunikacije. Rehabilitacioni tim koga čine fonijatri, logopedi, psiholozi i medicinske sestre zaslužan je za uspešnu rehabilitaciju oko 87% laringektomisanih pacijenata koji su savladali ezofagusni glas i govor. Psihološka rehabilitacija omogućava resocijalizaciju, povratak u porodično okruženje i društvene aktivnosti. Plod ove studije je i konačno formirano Udruženje laringektomisanih pacijenata Srbije. Ciljevi studije:1.Proceniti demografske i kliničke karakteristike laringektomisanih bolesnika i ispitati faktore od značaja za kvalitet života laringektomisanih bolesnika; 2.Evaluirati karakteristike ezofagusnog glasa i govora i izvršiti objektivizaciju kvaliteta uspostavljanja alarinksnog govora; 3.Proceniti osnovne psihometrijske karakteristike upitnika EORTC QLQ –C30 i EORTC QLQ H&N 43. Materijal i metode: Istraživanje je sprovedeno u Klinici za otorinolaringologiju i maksilofacijalnu hirurgiju Kliničkog centra Srbije u Beogradu u periodu od 01. marta 2012. do 01. marta 2015. godine. Ispitivanjem je obuhvaćeno 223 pacijenta kojima je zbog verifikovanog karcinoma larinksa učinjena totalna laringektomija u Klinici za otorinolaringologiju i maksilofacijalnu hirurgiju Kliničkog centra Srbije a fonijatrijska rehabilitacija je sprovedena u Odseku za fonijatriju Klinike. U okviru istraživanja pacijenti su podeljeni u dve grupe: • Prvu grupu je predstavljalo 168 laringektomisanih pacijenata koji su prošli sve planirane faze fonijatrijske rehabilitacije... Introduction: Quality of life currently represents the most modern concepts of science and it is considered the ideal of modern medicine. A holistic approach to the treatment of the human, not only a disease, plays an important role in the realization of the concept of health related to quality of life. In our community we do not pay adequate attention to the quality of life of laryngectomized patients. Total laryngectomy as a mutilant operation leads to drastic changes in life quality. A multidisciplinary rehabilitation program is essential for the laryngectomized patients to improve their quality of life. Phoniatric rehabilitation is the most important aspect of rehabilitation because it allows the restitution of verbal communication. Rehabilitation team, consisting of phoniatricians, speech therapists, psychologists and nurses, was responsible for the successful rehabilitation of about 87% of laryngectomized patients who have mastered the esophageal voice and speech. Psychological rehabilitation allows the resocialization, return to the family environment and social activities. The yield of this study is the final establishment of the Association of laryngectomized patients of Serbia. Objectives of the study: 1.Evaluate the demographic and clinical characteristics of laryngectomized patients and examine important factors for the life quality of laryngectomized patients; 2.Evaluate characteristics of esophageal voice and speech and perform objectification of quality established alaryngeal speech; 3.Evaluate basic psychometric characteristics of the questionnaire EORTC QLQ - C30 and EORTC QLQ H&N43. Material and Methods: The study was conducted at the Clinic of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Serbia in Belgrade, in the period from 1st March 2012 to 1st March 2015. The study included 223 patients, who were verified laryngeal cancer and underwent total laryngectomy in the Clinic of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Serbia and phoniatric rehabilitation was conducted in the Phoniatric Department. In this study the patients were divided into two groups: • The first group consisted of 168 laryngectomized patients who underwent all planned phases of phoniatric rehabilitation...

Published
2015

11. Radiographic cephalometry analysis of condylar position after bimaxillary osteotomy in patients with mandibular prognathism

Author

Miković, Nikola, Miković, Nikola, Lazarević, Miloš, Tatić, Zoran, Krejović-Trivić, Sanja, Petrović, Milan, Trivić, Aleksandar, Miković, Nikola, Miković, Nikola, Lazarević, Miloš, Tatić, Zoran, Krejović-Trivić, Sanja, Petrović, Milan, and Trivić, Aleksandar

Abstract

Background/Aim. Postoperative condylar position is a substantial concern in surgical correction of mandibular prognathism. Orthognathic surgery may change condylar position and this is considered a contributing factor for early skeletal relapse and the induction of temporomandibular disorders. The purpose of this study was to evaluate changes in condylar position, and to correlate angular skeletal measurements following bimaxillary surgery. Methods. On profile teleradiographs of 21 patients with mandibular angular and linear parametres, the changes in condylar position, were measured during preoperative orthodontic treatment and 6 months after the surgical treatment. Results. A statistically significant difference in values between the groups was found. The most distal point on the head of condyle point (DI) moved backward for 1.38 mm (p = 0.02), and the point of center of collum mandibulae point (DC) moved backward for 1.52 mm (p = 0.007). The amount of upward movement of the point DI was 1.62 mm (p = 0.04). Conclusion. In the patients with mandibular prognathism, the condyles tend to migrate upward and forward six months after bimaxillary surgery., Uvod/Cilj. Postoperativna pozicija kondila je značajna za hiruršku korekciju mandibularnog prognatizma. Ortognatska hirurgija može da promeni poziciju kondila, a to može biti jedan od faktora koji doprinosi ranom skeletnom recidivu i pojavi temporomandibularnih disfunkcija. Zbog toga je cilj ove studije bio da proceni promene pozicije kondila kao i da ne korelišu promene pozicije kondila sa angularnim skeletnim promenama nakon bimaksilarne hirurgije. Metode. Na telerendgenskim snimcima 21 bolesnika sa mandibularnim prognatizmom mereni su angularni i linearni parametri koji opisuju promene u položaju kondila, pre ortodontske pripreme i šest meseci nakon hirurške korekcije. Rezultati. Ustanovljena je statistička značajnost razlika u vrednosti parametara između grupa. Tačka DI - najdistalnija tačka na glavi kondila, pomerila se unazad 1,38 mm (p = 0,02), a tačka DC - tačka koja označava centar collum mandibulae, pomerila se, takođe, unazad za 1,52 mm (p = 0,007). Vrednost pomeranja tačke DI naviše bila je 1,62 mm (p = 0,04). Zaključak. Kod bolesnika sa mandibularnim prognatizmom, kondili su težili da migriraju unapred i naviše šest meseci nakon bimaksilarne operacije.

Published
2016

12. Laryngeal Granuloma - Benefit in Treatment with Zinc Supplementation?

Author

Đukić Vojko, Krejović-Trivić Sanja, Vukašinović Milan, Trivić Aleksandar, Pavlović Bojan, Milovanović Aleksandar, and Milovanović Jovica

Subjects
lcsh:Biochemistry, hemic and lymphatic diseases, laryngeal granuloma, Professional Paper, zinc supplementation, lcsh:QD415-436, conservative treatment
Abstract

Laryngeal granulomas present as contact and postintubation ulcers and granulomas. Essentially, a contact granuloma is a pseudotumor of the lateral wall of the posterior glottis. The most common etiological factor is voice abuse, with predisponing factors such as reflux disease. Postintubation ulcers and granulomas, although of different etiology, according to all the other traits belong to this clinical entity. The therapy of choice is conservative treatment. Surgical laser excision is indicated for resistant cases and those whose size is causing respiratory distress. Treatment of laryngeal granulomas with zinc supplementation is reported in the literature as one of the forms of conservative treatment, and we wanted to consider it in this review. Zinc is an essential mineral that plays a vital role in many biochemical reactions and is considered very important for wound healing.Larinksni granulom se predstavlja kontaktnim i postintubacionim ulkusom i granulomom. U suštini, kontaktni granulom je pseudotumorski izraštaj lateralnog zida zadnjeg dela glotisa. Najčešći etiološki faktor je neodgovarajuća upotreba glasa, uz predisponirajuće faktore kao što je refluksna bolest. Postintubacioni ulkus i granulom, iako drugačije etiologije, po svim ostalim osobinama pripadaju ovom kliničkom entitetu. Preporučena terapija je konzervativno lečenje, a hirurška laserska ekscizija indikovana je za rezistentne slučajeve i one koji svojom veličinom izazivaju respiratorne smetnje. U literaturi se pominje peroralna primena preparata cinka u terapiji larinksnog granuloma kao jedan od vidova konzervativnog lečenja, što smo i mi u ovom kratkom pregledu želeli da razmotrimo. Cink je esencijalni mineral koji igra ključnu ulogu u mnogim biohemijskim reakcijama i smatra se da je veoma važan za zarastanje rana.

Published
2013

13. Evaluacija parametara od značaja za kvalitet života laringektomisanih bolesnika

Author

Stanković, Predrag, Arsović, Nenad, Đorđević, Vladimir, Mitrović, Slobodan, Krejović Trivić, Sanja B., Stanković, Predrag, Arsović, Nenad, Đorđević, Vladimir, Mitrović, Slobodan, and Krejović Trivić, Sanja B.

Abstract

Uvod:Kvalitet života trenutno predstavlja najaktuelniji koncept savremene nauke i smatra se idealom moderne medicine. Holistički pristup lečenju čoveka a ne samo bolesti igra značajnu ulogu u ostvarenju koncepta kvaliteta života povezanog sa zdravljem. Kvalitetu života laringektomisanih bolesnika u našoj sredini nije posvećena adekvatna pažnja. Totalna laringektomija kao veoma mutilantna operacija dovodi do drastičnih promena u kvalitetu života. Multidisciplinarni rehabilitacioni program je neophodan laringektomisanim bolesnicima da bi poboljšali kvalitet života. Fonijatrijska rehabilitacija je najznačajniji vid rehabilitacije jer omogućava uspostavljanje verbalne komunikacije. Rehabilitacioni tim koga čine fonijatri, logopedi, psiholozi i medicinske sestre zaslužan je za uspešnu rehabilitaciju oko 87% laringektomisanih pacijenata koji su savladali ezofagusni glas i govor. Psihološka rehabilitacija omogućava resocijalizaciju, povratak u porodično okruženje i društvene aktivnosti. Plod ove studije je i konačno formirano Udruženje laringektomisanih pacijenata Srbije. Ciljevi studije:1.Proceniti demografske i kliničke karakteristike laringektomisanih bolesnika i ispitati faktore od značaja za kvalitet života laringektomisanih bolesnika; 2.Evaluirati karakteristike ezofagusnog glasa i govora i izvršiti objektivizaciju kvaliteta uspostavljanja alarinksnog govora; 3.Proceniti osnovne psihometrijske karakteristike upitnika EORTC QLQ –C30 i EORTC QLQ H&N 43. Materijal i metode: Istraživanje je sprovedeno u Klinici za otorinolaringologiju i maksilofacijalnu hirurgiju Kliničkog centra Srbije u Beogradu u periodu od 01. marta 2012. do 01. marta 2015. godine. Ispitivanjem je obuhvaćeno 223 pacijenta kojima je zbog verifikovanog karcinoma larinksa učinjena totalna laringektomija u Klinici za otorinolaringologiju i maksilofacijalnu hirurgiju Kliničkog centra Srbije a fonijatrijska rehabilitacija je sprovedena u Odseku za fonijatriju Klinike. U okviru istraživanja pacijenti su pod, Introduction: Quality of life currently represents the most modern concepts of science and it is considered the ideal of modern medicine. A holistic approach to the treatment of the human, not only a disease, plays an important role in the realization of the concept of health related to quality of life. In our community we do not pay adequate attention to the quality of life of laryngectomized patients. Total laryngectomy as a mutilant operation leads to drastic changes in life quality. A multidisciplinary rehabilitation program is essential for the laryngectomized patients to improve their quality of life. Phoniatric rehabilitation is the most important aspect of rehabilitation because it allows the restitution of verbal communication. Rehabilitation team, consisting of phoniatricians, speech therapists, psychologists and nurses, was responsible for the successful rehabilitation of about 87% of laryngectomized patients who have mastered the esophageal voice and speech. Psychological rehabilitation allows the resocialization, return to the family environment and social activities. The yield of this study is the final establishment of the Association of laryngectomized patients of Serbia. Objectives of the study: 1.Evaluate the demographic and clinical characteristics of laryngectomized patients and examine important factors for the life quality of laryngectomized patients; 2.Evaluate characteristics of esophageal voice and speech and perform objectification of quality established alaryngeal speech; 3.Evaluate basic psychometric characteristics of the questionnaire EORTC QLQ - C30 and EORTC QLQ H&N43. Material and Methods: The study was conducted at the Clinic of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Serbia in Belgrade, in the period from 1st March 2012 to 1st March 2015. The study included 223 patients, who were verified laryngeal cancer and underwent total laryngectomy in the Clinic of Otorhinolaryngology and Maxillofacial Surgery, Clini

Published
2015

15. Risk factors, prognostic factors and quality of life of patients with malignant tumours of the oral cavity and pharynx

Author

Andrejić, Dragoslava M., Milovanović, Jovica, Đukić, Vojko, Krejović-Trivić, Sanja, and Kosanović, Rade

Subjects
incidencija i mortalitet, trogodišnje preživljavanje, malignant tumours of the oral cavity and pharynx, quality of life, three-year survival period, faktori rizika, risk factors, prognostic factors, maligni tumori usne šupljine i ždrela, prognostički faktori, kvalitet života, incidence and mortality
Abstract

aligni tumori predstavljaju značajan medicinski problem i imaju veliki socijalno-ekonomski značaj. Česta su oboljenja u svim delovima sveta i zabrinjavajuća je sve veća učestalost malignih tumora i pomeranje starosne granice ka mlađim populacionim grupama. Među uzrocima smrtnosti nalaze se u svetu i kod nas na drugom mestu posle oboljenja kardiovaskularnog sistema. Značajna nova otkrića u oblasti dijagnostike i terapije su dovela do bitnog povećanja dužine preživljavanja obolelih što je aktuelizovalo pitanje kvaliteta života obolelih. Lečenje obolelih od malignih tumora usne šupljine i ždrela je složen medicinski i psihosociološki problem, zato što su operacije ovih tumora mutilantne i bitno menjaju način i kvalitet života; bolest kao takva uslovljava smanjenje radne sposobnosti, a nakon lečenja je neophodna kompletna psihološko-socijalna i fonijatrijska rehabilitacija. U cilju podizanja kvaliteta života obolelih i lečenih od malignih tumora usne šupljine i ždrela potrebna je sistematska, multidisciplinarna rehabilitacija bolesnika i edukativna adaptacija njegove okoline. Ispitivanje faktora rizika za nastajanje ovih malignih tumora omogućava nova saznanja koja se koriste pre svega u prevenciji bolesti. Praćenje dužine preživljavanja daje smernice u planiranju terapijskih modaliteta. Cilj rada je bio da se analizira kretanje obolevanja i umiranja od malignih tumora usne šupljine i ždrela tokom trinaest godina na području centralne Srbije; da se ispita kvalitet života obolelih od ovih malignih tumora u odnosu na demografske karakteristike, težinu kliničke slike i psihosocijalne parametre; da se identifikuju potencijalni faktori rizika za nastanak malignih tumora usne šupljine i ždrela i da se analizira trogodišnje preživljavanje obolelih. Metod. Analiza obolevanja od malignih tumora usne šupljine i ždrela je vršena korišćenjem podataka Instituta za javno zdravlje Srbije ,, Dr Milan Jovanović –Batut“ u Beogradu, a podaci o umrlima su dobijeni iz nepublikovanog materijala Zavoda za statistiku... Introduction. Malignant tumours represent a significant medical problem, with a considerable socio-economic impact. The disease is common in all parts of the world, with a worrying tendency of prevalence of malignant tumours and lowering of the age limit to include younger population groups. It is the second leading cause of death, both globally and in our country, after cardiovascular disease. Major new diagnostic and therapeutic discoveries resulted in a significantly enhanced length of survival for patients, which brought to the fore quality of life issues for patients. The treatment of patients with malignant tumours of the oral cavity and pharynx is a complex medical and psycho-social problem, as surgical treatment of these tumours tends to cause disfiguring and significantly alters the way and quality of life; the disease in itself causes reduced working abilities, and a full psycho-social and phoniatric rehabilitation is required once treatment is completed. Improving the quality of life of diseased and treated patients with malignant tumours of the oral cavity and pharynx requires systematic, multi-disciplinary rehabilitation of patient and an educational adaptation of his/her environment. Research into risk factors for the development of these malignant tumours provides new insights which are primarily used in prevention of disease. Monitoring of the length of survival provides guidelines for planning treatment modalities. The goal of this paper was to analyse incidence and mortality rates for malignant tumours of the oral cavity and pharynx over the thirteen years in central Serbia; to investigate the quality of life of patients with this type of malignant tumour in relation to demographic characteristics, severity of clinical presentation and psycho-social parameters. To identify potential risk factors for developing malignant tumours of the oral cavity and pharynx and to analyse a three-year survival period of patients...

Published
2018

Catalog

Books, media, physical & digital resources
See catalog results