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215 results on '"Krieger, Derk W."'

5. The ABC‐Stroke Risk Score and Effects of Atrial Fibrillation Screening on Stroke Prevention: Results From the Randomized LOOP Study

Author

Xing, Lucas Yixi, primary, Diederichsen, Søren Zöga, additional, Højberg, Søren, additional, Krieger, Derk W., additional, Graff, Claus, additional, Frikke‐Schmidt, Ruth, additional, Platonov, Pyotr G., additional, Olesen, Morten S., additional, Brandes, Axel, additional, Køber, Lars, additional, Haugan, Ketil Jørgen, additional, and Svendsen, Jesper Hastrup, additional

Published
2024
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9. Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder: insights from the LOOP Study

Author

Xing, Lucas Yixi, primary, Diederichsen, Søren Zöga, additional, Højberg, Søren, additional, Krieger, Derk W, additional, Graff, Claus, additional, Olesen, Morten S, additional, Nielsen, Jonas Bille, additional, Brandes, Axel, additional, Køber, Lars, additional, Haugan, Ketil Jørgen, additional, and Svendsen, Jesper Hastrup, additional

Published
2023
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10. Effects of Systematic Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide: a Secondary Analysis of the Randomized LOOP Study

Author

Xing, Lucas Yixi, primary, Diederichsen, Søren Zöga, additional, Højberg, Søren, additional, Krieger, Derk W., additional, Graff, Claus, additional, Frikke-Schmidt, Ruth, additional, Olesen, Morten S., additional, Brandes, Axel, additional, Køber, Lars, additional, Haugan, Ketil Jørgen, additional, and Svendsen, Jesper Hastrup, additional

Published
2023
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11. Searching for Atrial Fibrillation Poststroke: A White Paper of the AF-SCREEN International Collaboration

Author

Schnabel, Renate B., Haeusler, Karl Georg, Healey, Jeffrey S., Freedman, Ben, Boriani, Giuseppe, Brachmann, Johannes, Brandes, Axel, Bustamante, Alejandro, Casadei, Barbara, Crijns, Harry J.G.M., Doehner, Wolfram, Engström, Gunnar, Fauchier, Laurent, Friberg, Leif, Gladstone, David J., Glotzer, Taya V., Goto, Shinya, Hankey, Graeme J., Harbison, Joseph A., Hobbs, F.D. Richard, Johnson, Linda S.B., Kamel, Hooman, Kirchhof, Paulus, Korompoki, Eleni, Krieger, Derk W., Lip, Gregory Y.H., Løchen, Maja-Lisa, Mairesse, Georges H., Montaner, Joan, Neubeck, Lis, Ntaios, George, Piccini, Jonathan P., Potpara, Tatjana S., Quinn, Terence J., Reiffel, James A., Ribeiro, Antonio Luiz Pinho, Rienstra, Michiel, Rosenqvist, Mårten, Sakis, Themistoclakis, Sinner, Moritz F., Svendsen, Jesper Hastrup, Van Gelder, Isabelle C., Wachter, Rolf, Wijeratne, Tissa, and Yan, Bernard

Published
2019
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12. Observer Agreement on Computed Tomography Perfusion Imaging in Acute Ischemic Stroke

Author

El-Tawil, Salwa, Mair, Grant, Huang, Xuya, Sakka, Eleni, Palmer, Jeb, Ford, Ian, Kalra, Lalit, Wardlaw, Joanna, Muir, Keith W., Adami, Alessandro, Cerase, Alfonso, Garcia, Ana, von Heijne, Anders, Peeters, Andre, von Heijne, Anders, Zini, Andrea, Carneiro, Angelo, Patterson, Chris, Roffe, Christine, Freedman, Daniel, Scoffings, Daniel, Krieger, Derk W, Mitra, Dipayan, Berge, Eivind, Cora, Elena Adela, O’Brien, Eoin, Bertholds, Eric, Murat, Ethem, Moreton, Fiona, Tan, Garryck, Potter, Gillian, Rinaldi, Giuseppe, Madigan, Jeremy, Leyon, Joe, Du Plessis, Johann, Hewitt, Jonathan, Alves, José Eduardo, Egido, Jose, Sztriha, Laszlo, Esbjoernsson, Magnus, Correia, Manuel, Griebe, Martin, Dharmasiri, Michelle, Kirmi, Olga, Geraghty, Olivia, García-Bermejo, Pablo, Sutton, Patrick, Bhogal, Pervinder, White, Philip, Ferdinand, Phillip, Anjum, Qazi, Sellar, Robin, von Kummer, Rüdiger, Andole, Sreeman, Vundavalli, Sriram, Webb, Thomas, Das, Tilak, Matys, Tomasz, Goddard, Tony, Gontu, Vamsi, Sawlani, Vijay, Puetz, Volker, and Whiteley, Will

Published
2019
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15. EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke

Author

van der Worp, Bart H., Macleod, Malcolm R., Bath, Philip M. W., Demotes, Jacques, Durand-Zaleski, Isabelle, Gebhardt, Bernd, Gluud, Christian, Kollmar, Rainer, Krieger, Derk W., Lees, Kennedy R., Molina, Carlos, Montaner, Joan, Roine, Risto O., Petersson, Jesper, Staykov, Dimitre, Szabo, Istvan, Wardlaw, Joanna M., and Schwab, Stefan

Published
2014
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20. The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective

Author

Alroughani, Raed, VAN WIJMEERSCH, Bart, Al Khaboori, Jabber, Alsharoqi, Isa Ahmed, Ahmed, Samar F., Hassan, Ali, Inshasi, Jihad, Krieger, Derk W., Shakra, Mustafa, Shatila, Ahmed Osman, Szolics, Miklos, Khallaf, Mohamed, Ezzat, Aly, and Alroughani, Raed/0000-0001-5436-5804

Subjects
disease modifying therapies, patient profiles, alemtuzumab, Gulf region, multiple sclerosis, relapsing-remitting
Abstract

Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada (R)) is a highly efficacious DMT that shows better patient outcomes and therapeutic benefits, but its use is under-recognized in the Gulf region. Experts in the care of multiple sclerosis shared their opinions based on study data and daily clinical experience in identifying the appropriate patient profile suitable for alemtuzumab's therapeutic benefits. Age, disease activity and severity, disability status, physician experience, and economic condition are some of the key indicators for alemtuzumab use. The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The meeting of the expert group was organized and funded by Sanofi Genzyme. A medical writer (Haniya Dawn Panizales, Ogilvy Health and Wellness) provided medical writing assistance. All authors edited the manuscript for intellectual content and approved the final version. The final responsibility for the content lies with the authors. Alroughani, R (corresponding author), Al Amiri Hosp, Dept Med, Div Neurol, Kuwait, Kuwait. alroughani@gmail.com

Published
2020

23. Statin Use is Independently Associated with Smaller Infarct Volume in Nonlacunar MCA Territory Stroke

Author

Shook, Steven J., Gupta, Rishi, Vora, Nirav A., Tievsky, Andrew L., Katzan, Irene, and Krieger, Derk W.

Subjects
Cerebral arteries -- Health aspects, Cerebral arteries -- Research, Statins -- Dosage and administration, Statins -- Research, Stroke (Disease) -- Risk factors, Stroke (Disease) -- Research, Health
Abstract

To purchase or authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1552-6569.2006.00061.x Byline: Steven J. Shook (1), Rishi Gupta (1), Nirav A. Vora (1), Andrew L. Tievsky (1), Irene Katzan (1), Derk W. Krieger (1) Keywords: Brain ischemia; cerebrovascular accident; diffusion magnetic resonance imaging; hydroxymethylglutaryl (HMG)-CoA reductase inhibitors; retrospective studies; risk factors; treatment outcome Abstract: ABSTRACT Background. Studies have shown an association between HMG-CoA reductase inhibitors (statins) and improved stroke outcomes, possibly secondary to neuroprotective properties. Objective. To assess whether patients taking statins prior to ischemic stroke have smaller infarcts on magnetic resonance imaging (MRI), adjusting for other relevant clinical factors. Design. We retrospectively reviewed the Cleveland Clinic Foundation (CCF) Neurology Inpatient Database from June 2002 through June 2004. Demographics, medications, stroke subtype, diffusion-weighted imaging (DWI) infarct volume, admission NIHSS, and hours to MRI were collected. Patients with a nonlacunar middle cerebral artery (MCA) territory infarct and MRI less than 48 hours from symptom onset were included (n= 143). A multivariable linear regression model was constructed to determine independent predictors of smaller infarct volume. Results. A total of 143 patients were studied, including 38 patients taking statins at the time of their stroke. In univariate analysis, patients using statins were significantly more likely to have a history of hyperlipidemia, atrial fibrillation, and coronary artery disease and to be using coumadin, antiplatelet drugs, and angiotensin-converting enzyme inhibitors. Patients on statins had a tendency toward smaller infarcts in univariate analysis (median 25.4 cm.sup.3 vs. 15.5 cm.sup.3, P= 0.054). In multivariable linear regression analysis statin use, patient age, and TIA within the prior 4 weeks were independently associated with smaller DWI volumes; vessel occlusion on vascular imaging, and cardioembolic stroke subtype with larger infarct size. Conclusions. Statin use prior to the onset of nonlacunar MCA infarction was associated with a smaller infarct volume independent of other factors. Further studies utilizing both clinical and radiologic outcomes will be required to confirm these findings. Author Affiliation: (1)From the Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH (SS); Department of Neurology, Section of Stroke and Neurocritical Care, Cleveland, OH (NV, IK, DK); Department of Neurology, Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh, PA (NV); and Department of Radiology, Section of Neuroradiology, Cleveland, OH (AT), Department of Neurology, Division of Cerebrovasoular Diseases and Neuroendovascular Services, Michigan State University, East Lansing, MI (RG). Article History: Received March 14, 2006, and in revised form July 19, 2006. Accepted for publication July 25, 2006. Article note: Address correspondence to Derk W. Krieger, MD, PhD, Department of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, S-90, Cleveland, OH 44195. E-mail: krieged@ccf.org.

Published
2006

24. Intracranial Angioplasty and Stenting in the Awake Patient

Author

Abou-Chebl, Alex, Krieger, Derk W., Bajzer, Christopher T., and Yadav, Jay S.

Subjects
Angioplasty -- Health aspects, Angioplasty -- Research, Local anesthesia -- Health aspects, Local anesthesia -- Research, Stent (Surgery) -- Health aspects, Stent (Surgery) -- Research, Health
Abstract

To purchase or authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1552-6569.2006.00043.x Byline: Alex Abou-Chebl (1), Derk W. Krieger (1), Christopher T. Bajzer (1), Jay S. Yadav (1) Keywords: Anesthesia; complications; stenosis; stents; stroke prevention Abstract: ABSTRACT Background and Purpose. Endovascular treatment for intracranial atherosclerosis is evolving, but complications remain an issue. Most interventions are performed under general anesthesia, preventing intraprocedural clinical evaluations. We describe our approach to intracranial angioplasty and stenting, using local rather than general anesthesia, and intraprocedural neurological assessment. Methods. We prospectively collected procedural and outcome information on all patients undergoing intracranial angioplasty and stenting. Patients underwent interventions under local anesthesia with mild intravenous sedation or analgesia only if needed. Intraoperative neurological evaluations were performed, and symptomatology was used to guide the interventional technique. Results. Forty-eight arteries in 40 patients with a mean age of 65.2 years were treated. Thirty-two anterior and 16 posterior circulation segments were treated. Technical success was achieved in 100% of patients with reduction of the mean pretreatment stenosis from 85 [+ or -] 8.6% to 7 [+ or -] 10.1%. Stents were deployed in 40 segments; five patients were treated with drug-eluting stents. The cobalt-chromium coronary stents were the easiest to deliver. Thirty-seven patients were treated under local anesthesia and, of those, 61.4% experienced intraprocedural symptoms that led to some alteration of the interventional technique. Headache was the most common symptom, and, when persistent, it heralded the occurrence of subarachnoid hemorrhage. There were seven total neurological complications, but only five (10.5%) led to permanent morbidity (4 strokes) or mortality (1 death). Conclusions. Intracranial angioplasty and stenting can be successfully performed using coronary techniques and equipment including drug-eluting stents. Local anesthesia permits neurological evaluations and often leads to the adjustment of the interventional technique, potentially making the procedure safer. Author Affiliation: (1)From the Departments of Neurology (AA-C, DWK, JSY); and Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio (CTB, JSY). Article History: Received November 30, 2005, and in revised form February 16, 2006. Accepted for publication February 24, 2006. Article note: Address correspondence to Jay S. Yadav, MD, Department of Cardiovascular Medicine, F25, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195. E-mail: yadavj@ccf.org.

Published
2006

28. The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective

Author

Alroughani, Raed, primary, Van Wijmeersch, Bart, additional, Al Khaboori, Jabber, additional, Alsharoqi, Isa Ahmed, additional, Ahmed, Samar F., additional, Hassan, Ali, additional, Inshasi, Jihad, additional, Krieger, Derk W., additional, Shakra, Mustafa, additional, Shatila, Ahmed Osman, additional, Szolics, Miklos, additional, Khallaf, Mohamed, additional, and Ezzat, Aly, additional

Published
2020
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29. Relationship between left atrial strain, diastolic dysfunction and subclinical atrial fibrillation in patients with cryptogenic stroke: the SURPRISE echo substudy

Author

Olsen, Flemming J., primary, Christensen, Louisa M., additional, Krieger, Derk W., additional, Højberg, Søren, additional, Høst, Nis, additional, Karlsen, Finn M., additional, Svendsen, Jesper H., additional, Christensen, Hanne, additional, and Biering-Sørensen, Tor, additional

Published
2019
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30. Response to Letter by Morikawa

Author

Broderick, Joseph P., Connolly, E S., Kase, Carlos S., Vespa, Paul, Krieger, Derk W., Hanley, Daniel F., Mayberg, Marc, Feldmann, Edward, Morgenstern, Lewis B., Zuccarello, Mario, and Ogilvy, Christopher S.

Published
2008
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31. Response to Letter by Silva et al

Author

Broderick, Joseph P., Connolly, E S., Kase, Carlos S., Vespa, Paul, Krieger, Derk W., Hanley, Daniel F., Mayberg, Marc, Feldmann, Edward, Morgenstern, Lewis B., Zuccarello, Mario, and Ogilvy, Christopher S.

Published
2008
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46. ASSOCIATION BETWEEN LEFT ATRIAL STRAIN AND SUBCLINICAL ATRIAL FIBRILLATION IN PATIENTS WITH CRYPTOGENIC STROKE: THE SURPRISE ECHO SUBSTUDY

Author

Olsen, Flemming Javier, primary, Christensen, Louisa M., additional, Krieger, Derk W., additional, Højberg, Søren, additional, Høst, Nis B., additional, Karlsen, Finn M., additional, Gislason, Gunnar H., additional, Svendsen, Jesper Hastrup, additional, Christensen, Hanne K., additional, and Biering-Sorensen, Tor, additional

Published
2019
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49. Increasing value and reducing waste in stroke research

Author

Berge, Eivind, primary, Salman, Rustam Al-Shahi, additional, van der Worp, H Bart, additional, Stapf, Christian, additional, Sandercock, Peter, additional, Sprigg, Nikola, additional, Macleod, Malcolm R, additional, Kelly, Peter J, additional, Nederkoorn, Paul J, additional, Ford, Gary A, additional, Arnold, Marcel, additional, Berge, Eivind, additional, Diez-Tejedor, Exuperio, additional, Jatuzis, Dalius, additional, Krieger, Derk W, additional, and Weimar, Christian, additional

Published
2017
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50. Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial.

Author

van der Worp, H Bart, Macleod, Malcolm R, Bath, Philip MW, Bathula, Raj, Christensen, Hanne, Colam, Bridget, Cordonnier, Charlotte, Demotes-Mainard, Jacques, Durand-Zaleski, Isabelle, Gluud, Christian, Jakobsen, Janus Christian, Kallmünzer, Bernd, Kollmar, Rainer, Krieger, Derk W, Lees, Kennedy R, Michalski, Dominik, Molina, Carlos, Montaner, Joan, Roine, Risto O, and Petersson, Jesper

Published
2019
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