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15 results on '"Ktsoyan, Zhanna A."'

2. Extended-Spectrum β-Lactamases in Human Isolates of Multidrug-Resistant Non-typhoidal Salmonella enterica

Author

Sedrakyan, Anahit M., primary, Ktsoyan, Zhanna A., additional, Arakelova, Karine A., additional, Zakharyan, Magdalina K., additional, Hovhannisyan, Alvard I., additional, Gevorgyan, Zaruhi U., additional, Mnatsakanyan, Armine A., additional, Kakabadze, Elene G., additional, Makalatia, Khatuna B., additional, Chanishvili, Nina A., additional, Pirnay, Jean-Paul, additional, Arakelyan, Arsen A., additional, and Aminov, Rustam I., additional

Published
2020
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3. Characterization of Salmonella Isolates from Various Geographical Regions of the Caucasus and Their Susceptibility to Bacteriophages

Author

Makalatia, Khatuna, primary, Kakabadze, Elene, additional, Wagemans, Jeroen, additional, Grdzelishvili, Nino, additional, Bakuradze, Nata, additional, Natroshvili, Gulnara, additional, Macharashvili, Nino, additional, Sedrakyan, Anahit, additional, Arakelova, Karine, additional, Ktsoyan, Zhanna, additional, Zakharyan, Magdalina, additional, Gevorgyan, Zaruhi, additional, Mnatsakanyan, Armine, additional, Tishkova, Farida, additional, Lood, Cédric, additional, Vandenheuvel, Dieter, additional, Lavigne, Rob, additional, Pirnay, Jean-Paul, additional, De Vos, Daniel, additional, Chanishvili, Nina, additional, and Merabishvili, Maia, additional

Published
2020
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5. Potential Involvement of Salmonella Infection in Autoimmunity

Author

Ktsoyan, Zhanna, primary, Budaghyan, Lyudmila, additional, Agababova, Marina, additional, Mnatsakanyan, Armine, additional, Arakelova, Karine, additional, Gevorgyan, Zaruhi, additional, Sedrakyan, Anahit, additional, Hovhannisyan, Alvard, additional, Mkrtchyan, Mkhitar, additional, Zakharyan, Magdalina, additional, Arakelyan, Arsen, additional, and Aminov, Rustam, additional

Published
2019
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6. MULTIDRUG-RESISTANCE AND PRESENCE OF CLASS 1 INTEGRONS IN CLINICAL ISOLATES OF SALMONELLA ENTERICA SEROTYPE ENTERITIDIS, CIRCULATING IN ARMENIA

Author

Sedrakyan, Anahit M., Arakelova, K. A., Zakaryan, Magdalina K., Hovhanisyan, A. I., Asoyan, A. V., Z.U., Gevorkyan, Mnatsakanyan, A. A., Ktsoyan, Zhanna A., Boyajyan, A. S., and Aminov, Rustam

Subjects
Serotype, class 1 integrons, salmonella enterica serotype enteritidis, High prevalence, Immunology, Infectious and parasitic diseases, RC109-216, Subspecies, Biology, multidrug-resistance, Phenotype, Virology, Microbiology, Multiple drug resistance, Infectious Diseases, Antibiotic resistance, SDG 3 - Good Health and Well-being, Immunology and Allergy, Antibiotic use, Antibiotic resistance genes
Abstract

The aim of this work was detection of class 1 integrons and their contribution to the antimicrobial resistance phenotypes in strains of subspecies enterica serotype Enteritidis. S. Enteritidis strains (n = 29) were isolated from patients with salmonellosis at “Nork” Clinical Hospital of Infectious Diseases, Yerevan, Republic of Armenia. High prevalence of multi-drug resistance (MDR) phenotypes was revealed and isolates with MDR phenotypes which are rare in the S. Enteritidis serotype were observed. Class 1 integrons were detected in 27,6% of isolates, with the prevalence of a variable region of 1000 bp. Occurrence of the MDR phenotype was more frequent in integron-positive isolates compared to integron-negative isolates of S. Enteritidis. Further studies are necessary to reveal the genetic background of MDR phenotypes and to estimate the genetic kinship among the isolates. Our results suggest a rapid and large-scale penetration of antibiotic resistance genes into populations of S. Enteritidis, which complicates infection control. More rigorous regulations should be imposed on antibiotic use, together with a vigilant epidemiological surveillance, to prevent the emergence and spread of MDR S. Enteritidis.

Published
2014

7. Systemic Concentrations of Short Chain Fatty Acids Are Elevated in Salmonellosis and Exacerbation of Familial Mediterranean Fever

Author

Ktsoyan, Zhanna A., primary, Mkrtchyan, Mkhitar S., additional, Zakharyan, Magdalina K., additional, Mnatsakanyan, Armine A., additional, Arakelova, Karine A., additional, Gevorgyan, Zaruhi U., additional, Sedrakyan, Anahit M., additional, Hovhannisyan, Alvard I., additional, Arakelyan, Arsen A., additional, and Aminov, Rustam I., additional

Published
2016
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8. The role of microbiota in inflammation

Author

Ktsoyan, Zhanna A., Ghazaryan, Karine A., Khachatryan, Zaruhi A., Manukyan, Gayane P., Sedrakyan, А. М., Arakelova, Karine A., Gevorgyan, Z. U., Mnatsakanyan, A. A., Boyajyan, A. S., and Aminov, Rustam

Published
2014

9. Differential induction of total IgE by two Salmonella enterica serotypes

Author

Ktsoyan, Zhanna A., Mkrtchyan, Mkhitar S., Zakharyan, Magdalina K., Mnatsakanyan, Armine A., Arakelova, Karine A., Gevorgyan, Zaruhi U., Ktsoyan, Lusntag A., Sedrakyan, Anahit, Hovhannisyan, Alvard I, Ghazaryan, Karine A., Boyajyan, Anna S., Aminov, Rustam, Ktsoyan, Zhanna A., Mkrtchyan, Mkhitar S., Zakharyan, Magdalina K., Mnatsakanyan, Armine A., Arakelova, Karine A., Gevorgyan, Zaruhi U., Ktsoyan, Lusntag A., Sedrakyan, Anahit, Hovhannisyan, Alvard I, Ghazaryan, Karine A., Boyajyan, Anna S., and Aminov, Rustam

Abstract

The main goal of this study was to establish how the inflammation caused by infection with two different Salmonella enterica serotypes, S. Typhimurium and S. Enteritidis, may lead to the predisposition to allergy as measured by total IgE level in the blood. Infection by S. Typhimurium did not affect the systemic IgE concentration while in S. Enteritidis-infected patients there was a significant 3.5-fold increase. This effect was especially profound in patients >4 years old, with up to the 8-fold increase above the norm. The degree of dysbiosis in these two infections measured with the comparative counts of cultivated bacteria showed an inverse relationship with the IgE concentration. Earlier we reported the elevated level of IL-17 in patients infected by S. Enteritidis. In the current study a significant correlation was found between the concentrations of IL-17 and IgE suggesting a possible role played by this cytokine in triggering the production of IgE in response to S. Enteritidis infection.

Published
2015

10. Differential induction of total IgE by two Salmonella enterica serotypes

Author

Ktsoyan, Zhanna A., primary, Mkrtchyan, Mkhitar S., additional, Zakharyan, Magdalina K., additional, Mnatsakanyan, Armine A., additional, Arakelova, Karine A., additional, Gevorgyan, Zaruhi U., additional, Ktsoyan, Lusntag A., additional, Sedrakyan, Anahit Ì., additional, Hovhannisyan, Alvard I., additional, Ghazaryan, Karine A., additional, Boyajyan, Anna S., additional, and Aminov, Rustam I., additional

Published
2015
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11. Inflammatory Responses to Salmonella Infections Are Serotype-Specific

Author

Ktsoyan, Zhanna, primary, Ghazaryan, Karine, additional, Manukyan, Gayane, additional, Martirosyan, Anush, additional, Mnatsakanyan, Armine, additional, Arakelova, Karine, additional, Gevorgyan, Zaruhi, additional, Sedrakyan, Anahit, additional, Asoyan, Ara, additional, Boyajyan, Anna, additional, and Aminov, Rustam, additional

Published
2013
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12. Management of familial Mediterranean fever by colchicine does not normalize the altered profile of microbial long chain fatty acids in the human metabolome

Author

Ktsoyan, Zhanna A., primary, Beloborodova, Natalia V., additional, Sedrakyan, Anahit M., additional, Osipov, George A., additional, Khachatryan, Zaruhi A., additional, Manukyan, Gayane P., additional, Arakelova, Karine A., additional, Hovhannisyan, Alvard I., additional, Arakelyan, Arsen A., additional, Ghazaryan, Karine A., additional, Zakaryan, Magdalina K., additional, and Aminov, Rustam I., additional

Published
2013
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13. Profiles of Microbial Fatty Acids in the Human Metabolome are Disease-Specific

Author

Ktsoyan, Zhanna A., primary, Beloborodova, Natalia V., primary, Sedrakyan, Anahit M., primary, Osipov, George A., primary, Khachatryan, Zaruhi A., primary, Kelly, Denise, primary, Manukyan, Gayane P., primary, Arakelova, Karine A., primary, Hovhannisyan, Alvard I., primary, Olenin, Andrey Y., primary, Arakelyan, Arsen A., primary, Ghazaryan, Karine A., primary, and Aminov, Rustam I., primary

Published
2011
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