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483 results on '"Kubo, Naoshi"'

7. Successful robotic‐assisted resection of an esophageal duplication cyst in the upper thoracic esophagus: A case report with surgical video.

Author

Matsuoka, Kohei, Kubo, Naoshi, Sakurai, Katsunobu, Hasegawa, Tsuyoshi, Nishimura, Junya, Iseki, Yasuhito, Murata, Akihiro, Kodai, Shintaro, Nishii, Takafumi, Shimizu, Sadatoshi, Inoue, Toru, Nishiguchi, Yukio, and Maeda, Kiyoshi

Subjects
*CHRONIC cough, *SURGERY, *CYSTS (Pathology), *ESOPHAGUS, *COUGH, *COMPUTED tomography, *HOARSENESS
Abstract

Esophageal duplication cysts are rare congenital noncancerous growths. Symptoms of this disease are reported to be asymptomatic in approximately 70% but include respiratory symptoms such as coughing and difficulty breathing. Minimally invasive removal of these cysts without esophagectomy is typically recommended. However, when the cyst is situated in the upper mediastinum, surgical excision becomes technically challenging. Here, we report a case of an obese female patient with esophageal duplication cyst in the upper mediastinum who underwent successfully robotic‐assisted complete removal of the cyst. A 50‐year‐old woman presented to a local clinic with a persistent cough and hoarseness lasting 4 months. A computed tomography scan revealed a large cystic tumor in the upper mediastinum, causing displacement of the trachea. The resection of the cystic tumor was safely performed with robotic assistance. The use of robotic system for the removal of esophageal duplication cyst is technically safe and feasible. [ABSTRACT FROM AUTHOR]

Published
2024
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10. How do we prevent severe intra‐abdominal infectious complications following minimally invasive gastrectomy for cancer? The usefulness of a novel marker using computed tomography images (minimum umbilicus–vertebra diameter) and robotic surgery.

Author

Kubo, Naoshi, Sakurai, Katsunobu, Hasegawa, Tsuyoshi, Nishimura, Junya, Iseki, Yasuhito, Nishii, Takafumi, Shimizu, Sadatoshi, Inoue, Toru, Nishiguchi, Yukio, and Maeda, Kiyoshi

Subjects
SURGICAL robots, COMPUTED tomography, CANCER invasiveness, RECEIVER operating characteristic curves, PROPENSITY score matching
Abstract

Background: Intra‐abdominal infectious complications (IAICs) following minimally invasive gastrectomy (MIG) for cancer sometimes worsen short‐ and long‐term outcomes. In this study, we focused on the minimum umbilicus–vertebra diameter (MUVD) in preoperative computed tomography (CT) images and robotic surgery to prevent severe IAIC occurrence. Patients and Methods: A total of 400 patients with gastric cancer who underwent 204 laparoscopic gastrectomy (LG) and 196 robotic gastrectomy (RG) procedures were enrolled in this study. We retrospectively investigated the significance of the MUVD and robotic surgery for preventing severe IAICs following MIG using multivariate and propensity score matching analysis. Results: The MUVD cutoff value was 84 mm by receiver operating characteristic (ROC) curve using severe IAICs as the end point. The MUVD and visceral fat area (VFA) had significantly higher area under the curve (AUC) than BMI (MUVD vs. BMI, p = 0.032; VFA vs. BMI, p < 0.01). In the multivariate analysis, high MUVD (HR, 9.46; p = 0.026) and laparoscopic surgery (HR, 3.35; p = 0.042) were independent risk factors for severe IAIC occurrence. In the propensity matching analysis between robotic and laparoscopic surgery in the high MUVD group, the RG group tended to have a lower severe IAIC rate than the LG group (0% vs. 9.8%, p = 0.056). Conclusion: The MUVD was a novel and easy‐measuring predictor of severe IAICs following MIG. Robotic surgery should be considered first in patients with gastric cancer having an MUVD value of 84 mm or higher from the perspective of severe IAIC occurrence. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Impact of a robotic system on intra‐abdominal infectious complications after minimally invasive gastrectomy in patients with gastric cancer: A propensity score matching analysis regarding visceral obesity.

Author

Kubo, Naoshi, Sakurai, Katsunobu, Hasegawa, Tsuyoshi, Tamamori, Yutaka, Iseki, Yasuhito, Nishii, Takafumi, Shimizu, Sadatoshi, Inue, Toru, Nishiguchi, Yukio, and Maeda, Kiyoshi

Subjects
PROPENSITY score matching, PANCREATICODUODENECTOMY, STOMACH cancer, CANCER patients, GASTRECTOMY, MINIMALLY invasive procedures
Abstract

Background: The efficacy of robotic gastrectomy (RG) on postoperative complications in patients with gastric cancer (GC) is unclear in terms of the volume of intra‐abdominal fat tissue. Patients and Methods: We enrolled 403 patients with GC who had minimally invasive surgery between January 2015 and July 2022. During this time, 197 RG and 206 laparoscopic gastrectomies (LG) were performed on the study participants. According to the computed tomography scan, patients were defined as having or not having visceral obesity based on the visceral fatty area (VFA). In each high and low VFA group, we compared short‐term outcomes between the RG group and LG group. Results: After PS matching for patients with high VFA, the two groups were well matched, with 71 cases in both the RG and LG groups. The median surgical time in the RG group was significantly longer (420 vs. 365 min, p < 0.001). However, the RG group had a significantly lower rate of severe intra‐abdominal infectious complications (IAIC), such as anastomotic leakage, pancreatic fistula, and intra‐abdominal abscess (1.4% vs. 15.4%, p = 0.004). However, among the 77 patients with low VFA values, we found no significant difference in the rate of severe IAIC between the two groups (1.1% in the RG group vs. 2.6% in the LG group, p = 1.00). Conclusion: RG may be a viable alternative to LG because of the lower postoperative IAIC for patients with visceral obesity and GC. However, RG may not benefit non‐obese patients. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Preoperative Frailty Assessed Comprehensively by a Questionnaire Predicts a Poor Survival Following Curative Resection of Gastric Cancer

Author

TAMURA, TATSURO, primary, SAKURAI, KATSUNOBU, additional, RYU, KAORU, additional, MURATA, TOMOKO, additional, MIYAMOTO, HIRONARI, additional, NISHI, SATOSHI, additional, DEGUCHI, SOTA, additional, NAMBARA, MIKIO, additional, MIKI, YUICHIRO, additional, YOSHII, MAMI, additional, TOYOKAWA, TAKAHIRO, additional, KUBO, NAOSHI, additional, TANAKA, HIROAKI, additional, LEE, SHIGERU, additional, OHIRA, MASAICHI, additional, and MAEDA, KIYOSHI, additional

Published
2023
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16. Impact of a robotic system on intra‐abdominal infectious complications after minimally invasive gastrectomy in patients with gastric cancer: A propensity score matching analysis regarding visceral obesity

Author

Kubo, Naoshi, primary, Sakurai, Katsunobu, additional, Hasegawa, Tsuyoshi, additional, Tamamori, Yutaka, additional, Iseki, Yasuhito, additional, Nishii, Takafumi, additional, Shimizu, Sadatoshi, additional, Inue, Toru, additional, Nishiguchi, Yukio, additional, and Maeda, Kiyoshi, additional

Published
2023
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22. Ulcerative Colitis-Associated Colorectal Cancer is Frequently Associated with the Microsatellite Instability Pathway

Author

Fujiwara, Ichiro, Yashiro, Masakazu, Kubo, Naoshi, Maeda, Kiyoshi, and Hirakawa, Kosei

Abstract

Purpose: Patients with ulcerative colitis have a high risk for the development of colorectal cancer. To understand the molecular mechanisms of the carcinogenesis process of ulcerative colitis-associated colorectal cancer, the genetic alterations in inflamed or neoplastic colon epithelium in ulcerative colitis were analyzed. Methods: Fifty-seven patients with ulcerative colitis were enrolled in this study. Specimens were obtained from the patients randomly at six colonic sites. Each patient was histologically classified according to the worst pathologic finding into cancer, dysplasia, indefinite, and normal cases. Microsatellite instability, mutations of target genes, hypermethylation of the hMLH1 promoter region, and mismatch repair protein expression were analyzed. Results: High-microsatellite instability was found in 4 of 11 cancer cases (36 percent), 5 of 15 dysplasia cases (33 percent), 5 of 11 indefinite cases (45 percent), and none of 20 normal cases (0 percent). A significant correlation was found between the malignant potential and high-microsatellite instability. A frameshift mutation of transforming growth factor β receptor Type II (TGFβRII) was significantly correlated with worsening histologic grade. High-microsatellite instability was significantly associated with hMLH1 hypermethylation and loss of hMSH2 expression. Conclusion: The carcinogenesis process in ulcerative colitis-associated colorectal cancer was closely associated with the microsatellite instability pathway through TGFβRII mutation by a dysfunction of the mismatch repair system.

Published
2024
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24. Successful surgical treatment for nonocclusive mesenteric ischemia of a wide area of the intestine accompanied by gastric conduit necrosis after esophagectomy for esophageal cancer: a case report and review of the literature

Author

Miura, Kotaro, Kubo, Naoshi, Sakurai, Katsunobu, Tamamori, Yutaka, Murata, Akihiro, Nishii, Takafumi, Kodai, Shintaro, Tachimori, Akiko, Shimizu, Sadatoshi, Kanazawa, Akishige, Inoue, Toru, Nishiguchi, Yukio, and Maeda, Kiyoshi

Published
2020
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49. Preoperative C-reactive Protein-to-albumin Ratio Predicts Anastomotic Leakage After Esophagectomy for Thoracic Esophageal Cancer: a Single-center Retrospective Cohort Study

Author

Sugimoto, Atsushi, primary, Toyokawa, Takahiro, additional, Miki, Yuichiro, additional, Yoshii, Mami, additional, Tamura, Tatsuro, additional, Sakurai, Katsunobu, additional, Kubo, Naoshi, additional, Tanaka, Hiroaki, additional, Lee, Shigeru, additional, Muguruma, Kazuya, additional, Yashiro, Masakazu, additional, and Ohira, Masaichi, additional

Published
2021
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