Search

Your search keyword '"Kugelmass, Aaron"' showing total 173 results
Start Over Author "Kugelmass, Aaron"
173 results on '"Kugelmass, Aaron"'

15. Elevation of the creatine kinase myocardial isoform following otherwise successful directional coronary atherectomy and stenting

Author

Kugelmass, Aaron D., Cohen, David J., Moscucci, Mauro, Piana, Robert N., Senerchia, Cynthia, Kuntz, Richard E., and Baim, Donald S.

Subjects
Coronary arteries, Arterial catheterization -- Physiological aspects, Stent (Surgery) -- Physiological aspects, Creatine kinase -- Physiological aspects, Health
Abstract

Moderate elevation of creatine kinase (CK) MB isoform is common following otherwise successful percutaneous coronary revascularization, and is frequently interpreted as evidence of a non-Q-wave myocardial infarction. It is not clear, however, whether elevation of CK MB isoform carries sufficient adverse clinical impact to be categorized as a 'major' complication. We therefore explored the incidence and clinical consequence of elevation of CK MB isoform in a consecutive series of 565 patients who had otherwise successful directional coronary atherectomy (n = 274) or stenting (n = 291), and were followed for a mean of 2 years. Of this cohort, 11.5% had postprocedure elevation of the CK MB isoform above normal (10 IU/liter). These patients tended to be older and to have undergone atherectomy of a de novo lesion with adverse morphology (thrombus, calculation, eccentricity). Patients with elevation of CK MB isoform following otherwise successful revascularization generally showed no adverse long-term sequelae (death, recurrent myocardial infarction, rrpent revascularization) compared with patients without elevation of CK MB isoform. Only 2.3% of the patients who had CK MB isoform release SO IU/liter) are less common (2.3%), but appear to adversely affect long-term clinical outcome and should thus probably be considered along with Q-wave myocardial infarction as a major complication in reporting new device results. (Am J Cardiol 1994;74:748-754)

Published
1994

16. Is 40% to 70% diameter narrowing at the site of previous stenting or directional coronary atherectomy clinically significant?

Author

Gordon, Paul C., Friedrich, Steven P., Piana, Robert N., Kugelmass, Aaron D., Leidig, Gilbert A., Gibson, C. Michael, Cohen, David J., Carrozza, Joseph P., Kuntz, Richard E., and Baim, Donald S.

Subjects
Arteries -- Stenosis, Myocardial revascularization -- Complications, Health
Abstract

Traditional binary definitions of coronary restenosis based on 6-month continuous angiographic measurements (e.g., >50% diameter stenosis) may give confusing results for lesions whose late percent stenosis falls near the arbitrary threshold. To determine the long-term clinical consequences of such lesions, the overall correlation between follow-up percent stenosis and the performance of subsequent ischemia-driven target vessel revascularization (triggered by significant angina or a positive exercise study result, or both) was examined in 443 consecutive lesions treated with directional coronary atherectomy or Palmaz-Schatz coronary stenting. Follow-up angiograms (available in 355 lesions, 82%) were stratified into 3 groups: severe late stenosis (>70% stenosis, n = 59), moderate late stenosis (40% to 70% stenosis, n = 72), and minimal late stenosis (50%) showed a similarly favorable long-term clinical outcome to patients with a minimal late stenosis. These results support a strategy of conservative management for the 20% of patients who have a moderate (40% to 70%) late stenosis after stenting or atherectomy, but do not have evidence of ischemia.

Published
1994

17. Effect of prior coronary restenosis on the risk of subsequent restenosis after stent placement of directional atherectomy

Author

Moscucci, Mauro, Piana, Robert N., Kuntz, Richard E., Kugelmass, Aaron D., Carrozza, Joseph P., Senerchia, Cynthia, and Baim, Donald S.

Subjects
Stent (Surgery) -- Complications, Arteries -- Stenosis, Health
Abstract

Lesions that have developed restenosis after a prior intervention may be more likely to develop restenosis after subsequent percutaneous interventions. To determine if this is an independent effect, the clinical characteristics and immediate angiographic outcomes of 179 prior restenosis lesions were compared with those of 254 primary lesions after stenting or directional atherectomy. Six-month angiographic follow-up was obtained for 79% of successfully treated lesions. Univariable and multivariable logistic regression was used to determine how binary restenosis (defined as [greater than or equal to]50% diameter stenosis at follow-up) was influenced by postprocedure luminal diameter, left anterior desconding artery location, diabetes mellitus, as well as prior restenosis. At 6-month follow-up, prior restenosis lesions had a significantly smaller late diameter (1.77 vs 2.18 mm, p

Published
1994

19. Balloon postdilation can safely improve the results of successful (but suboptimal) directional coronary atherectomy

Author

Gordon, Paul C., Kugelmass, Aaron D., Cohen, David J., Breall, Jeffrey A., Friedrich, Steven P., Carrozza, Joseph P., Jr., Diver, Daniel J., Kuntz, Richard E., and Baim, Donald S.

Subjects
Transluminal angioplasty -- Usage, Angioplasty -- Complications, Coronary arteries, Health
Abstract

This study investigates whether adjunctive balloon angioplasty can be safely used to improve acute results in cases where directional coronary atherectomy alone has provided a successful (but suboptimal) outcome. Between October 1, 1990, and October 1, 1992, directional coronary atherectomy was performed successfully in 198 of 228 lesions. Individual operators believed that most acute results were satisfactory after atherectomy alone (group I, n = 115) with a minimal lumen diameter that increased from 0.82 [+ or -] 0.45 to 3.21 [+ or -] 0.65 mm after atherectomy, for an acute gain in lumen diameter of 2.39 [+ or -] 0.73 mm and a residual stenosis of 6 [+ or -] 13%. In 42% of lesions (group II, n = 83), however, results were considered suboptimal after atherectomy alone, with a minimal lumen diameter that increased from 0.85 [+ or -] 0.45 to 2.83 [+ or -] 0.64 mm, a smaller acute gain of 1.96 [+ or -] 0.72 mm, and a mean residual stenosis of 17 [+ or -] 14% (although all residual stenoses were 30%). Adjunctive balloon angioplasty in these group II lesions provided an additional gain of 0.34 [+ or -] 0.38 mm, bringing the total acute gain for group II lesion to 2.32 [+ or -] 0.78 mm and the residual stenosis to 9 [+ or -] 13%, similar to that of group I patients who underwent atherectomy alone. This strategy resulted in a 7 [+ or -] 13% overall residual stenosis for the study population, with no higher incidence of periprocedural complications or adverse late clinical outcomes in group II patients. Thus, adjunctive balloon angioplasty following directional coronary atherectomy can be used effectively to optimize postprocedural lumen diameter without adversely affecting either immediate safety or late clinical outcome. (Am J Cardiol 1993;72:71E-79E)

Published
1993

26. Active Lipid Management In Coronary Artery Disease (ALMICAD) Study

Author

Khanal, Sanjaya, Obeidat, Omar, Hudson, Michael P., Al-Mallah, Mouaz, Bloome, Mary, Lu, Mei, Greenbaum, Adam B., Kugelmass, Aaron D., and Weaver, W. Douglas

Subjects
Coronary heart disease -- Research, Coronary heart disease -- Risk factors, Coronary heart disease -- Care and treatment, Lipids -- Research, Lipids -- Health aspects, Health, Health care industry
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjmed.2006.06.048 Byline: Sanjaya Khanal, Omar Obeidat, Michael P. Hudson, Mouaz Al-Mallah, Mary Bloome, Mei Lu, Adam B. Greenbaum, Aaron D. Kugelmass, W. Douglas Weaver Keywords: Lipid clinic; Outcomes; Secondary prevention Abstract: Many providers have implemented specialized lipid clinics to more effectively identify, monitor, and treat hyperlipidemia in patients with coronary artery disease. The effectiveness of such a strategy is not known. We sought to investigate whether a specialized clinic achieves better lipid results and clinical outcomes than standard care. Author Affiliation: Henry Ford Heart and Vascular Institute, Henry Ford Hospital, Detroit, Mich Article Note: (footnote) Supported in part by unrestricted grants from Merck and Co, New Jersey, and Henry Ford Heart and Vascular Institute, Detroit, Michigan.

Published
2007

28. The Comparison of Physician to Computer Interpreted Electrocardiograms on ST-elevation Myocardial Infarction Door-to-balloon Times

Author

Mawri, Sagger, primary, Michaels, Alexander, additional, Gibbs, Joseph, additional, Shah, Sunay, additional, Rao, Sunil, additional, Kugelmass, Aaron, additional, Lingam, Natesh, additional, Arida, Muhammad, additional, Jacobsen, Gordon, additional, Rowlandson, Ian, additional, Iyer, Karthik, additional, Khandelwal, Akshay, additional, and McCord, James, additional

Published
2016
Full Text
View/download PDF

35. IS MULTIVESSEL PRIMARY PCI ADVISABLE? DIFFERENCES IN CLINICAL OUTCOMES AMONG MEDICARE BENEFICIARIES WITHOUT CARDIOGENIC SHOCK UNDERGOING SINGLE VERSUS MULTI-VESSEL PCI DURING A PRIMARY ST-SEGMENT ELEVATED MYOCARDIAL INFARCTION HOSPITALIZATION IN FISCAL YEAR 2011

Author

Kugelmass, Aaron D., primary, Brown, Phillip P., additional, Cohen, David J., additional, Reynolds, Matthew R., additional, Culler, Steven D., additional, and Simon, April W., additional

Published
2014
Full Text
View/download PDF

48. Early Invasive Strategy Improves Outcomes in Patients With Acute Coronary Syndrome With Previous Coronary Artery Bypass Graft Surgery

Author

Kugelmass, Aaron D., primary, Sadanandan, Saihari, additional, Lakkis, Nasser, additional, Dibattiste, Peter M., additional, Robertson, Debbie H., additional, Demopoulos, Laura A., additional, Gibson, C Michael, additional, Weintraub, William S., additional, Murphy, Sabina A., additional, and Cannon, Christopher P., additional

Published
2006
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results