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4. Oligohydramnios at term in the high-risk population – how severe is severe?

Author

Pekar-Zlotin, Marina, Hirsh, Nimrod, Melcer, Yaakov, Wiener, Yifat, Kugler, Nadav, Zilberman Sharon, Nataly, and Maymon, Ron

Subjects
ANEMIA, RISK assessment, CESAREAN section, STATISTICAL correlation, PEARSON correlation (Statistics), ACADEMIC medical centers, T-test (Statistics), GESTATIONAL diabetes, HYPERTENSION, LOGISTIC regression analysis, SEVERITY of illness index, PREGNANCY outcomes, RETROSPECTIVE studies, CHI-squared test, DESCRIPTIVE statistics, LONGITUDINAL method, INDUCED labor (Obstetrics), PREECLAMPSIA, GESTATIONAL age, ONE-way analysis of variance, AMNIOTIC liquid, PREGNANCY complications, COMPARATIVE studies, DATA analysis software, ASTHMA, OBESITY
Abstract

The term oligohydramnios is linked to pregnancy complications. We previously presented the outcome of the low-risk population (no pregnancy complications) with term oligohydramnios. This study aims to address the high-risk group (Any maternal complication during pregnancy, such as gestational diabetes, pre-gestational diabetes, chronic hypertension, preeclampsia, anemia, asthma, obesity, and multi parity.) This retrospective cohort study of 1,114 singleton term (≥37), oligohydramnios (AFI <50 mm) pregnancies from Shamir Medical Center between 2017 and 2021. Compering the low-risk to high-risk groups with subdivision by severity of oligohydramnios. A total of 211 subjects (19 %) were high-risk cases and 903 (81 %) low-risk cases. Comparing these two groups, subjects of the high-risk group were older (31.34 ± 5.85 vs. 29.51 vs. 4.96), had earlier gestational age at delivery 39.53 ± 1.18 vs. 40, had higher mean AFI (35 ± 12.7 vs. 33 ± 14.5), were subject to more labor inductions (81 vs. 69.7 %), and CS rate (19.9 vs. 12.4 %). Logistic regression revealed a need for more cesarean sections in the high-risk group. Additionally, more labor inductions and a higher risk of negative fetal outcomes. This study highlights the importance of considering pregnancy risk factors when we are approaching oligohydramnios in high-risk pregnancies. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Author

Nepogodiev, Dmitri, Bhangu, Aneel, Glasbey, James C, Li, Elizabeth, Omar, Omar M, Simoes, Joana FF, Abbott, Tom EF, Alser, Osaid, Arnaud, Alexis P, Bankhead-Kendall, Brittany K, Breen, Kerry A, Cunha, Miguel F, Davidson, Giana H, Di Saverio, Salomone, Gallo, Gaetano, Griffiths, Ewen A, Gujjuri, Rohan R, Hutchinson, Peter J, Kaafarani, Haytham MA, Lederhuber, Hans, Löffler, Markus W, Mashbari, Hassan N, Minaya-Bravo, Ana, Morton, Dion G, Moszkowicz, David, Pata, Francesco, Tsoulfas, George, Venn, Mary L, Cox, Daniel, Roslani, April C, Alakaloko, Felix, de Vries, Jean-Paul PM, Aaraj, Mahmoud A, Abbott, Sarah J, Abdalla, Mutwakil OM, Abdelaal, Ahmed S, Ademuyiwa, Adesoji O, Aherne, Thomas M, Ali, Osman M, Alkadeeki, Ghadah Z, Almeida, Ana C, Alrahawy, Mahmoud M, Ambler, Graeme K, Alameer, Ehab, Andreani, Stefano M, De Andrés-Asenjo, Beatriz, Antonanzas, Leyre Lopez, Aoun, Salah G, Ashoush, Fouad M, Augestad, Knut Magne, Avellana, Rocio B, Ayeni, Funbi A, Ayorinde, John OO, Babu, Bheemanakone H, Baig, Mirza MAS, Bajomo, Oreoluwa M, Baker, Olivia J, Baker, Markus P, Baldwin, Alexander J, Ban, Vin Shen, Baron, Ryan D, Barranquero, Alberto G, Barry, Conor P, DI Bartolomeo, Alessandro, Bass, Gary A, Bath, Michael F, Batjer, H Hunt, Beamish, Andrew J, Belgaumkar, Ajay P, Bence, Matthew N, Benson, Ruth A, Bernal-Sprekelsen, Juan Carlos, Bhama, Anuradha R, Bhavaraju, Avi V, Biffl, Walter L, Blundell, Chris M, Boddy, Alexander P, Borgstein, Alexander BJ, Bosanquet, David C, Bosch, Karen D, Bouhuwaish, Ahmad EM, Bozkurt, Mehmet A, Brathwaite, Collin EM, Brown, Benjamin C, Brown, Oliver D, Brown, Allison K, Buarque, Igor Lima, Bueno-Cañones, Alejandro D, Bulugma, Mustafa R, Burke, Joshua R, Byrne, Matthew HV, Cagigal-Ortega, Elima P, Callcut, Rachael A, DI Candido, Francesca, Canova, Michaela E, Carlos, William J, Caruana, Edward J, Cato, Liam D, Catton, Andrew B, Ceretti, Andrea Pisani, Chase, Thomas JG, Chiara, Francesco Di, Chowdhury, Abeed H, Chung, Eric A, Cicerchia, Pierfranco M, Clough, Ethan CS, Coleman, Natasha L, Collins, Chris G, Collins, Michelle L, Colonna, Emily T, Comini, Lara V, Coughlin, Patrick A, Cruzado, Laura Fernández-Gomez, Davidson, Brian R, Davies, Richard J, Davies, Emma J, Davis, Niall F, Dawson, Brett E, Dean, Benjamin JF, Delgado, Maria Garcia-Conde, Diaz, Jose J, Dickson, Kathryn E, Diez-Alonso, Manuel M, Dixon, Jan R, Doe, Matthew J, Drake, Thomas D, Drake, Frederick T, Duffy, John P, Dunne, Declan FJ, Dunne, Naomi JM, Durán-Muñoz-Cruzado, Virginia M, Durst, Alexander ZE, Eardley, Nicola J, Edwards, John G, Elfallal, Ahmed H, Elfiky, Mahmoud MA, Elliott, Jessie A, Emile, Sameh H, Emslie, Katy M, Endorf, Frederick W, Engel, Jamie L, Enjuto, Diego T, Etchill, Eric W, Evans, Jonathan P, Fahey, Brian A, Faria, Carlos S, Feo, Carlo V, Ferguson, Henry JM, Fernandez, Beatriz Dieguez, Fernandez, Andres Garcia, Fernández, Antonio J, Fernández-Pacheco, Borja Camacho, Fitzgerald, J Edward, Fonsi, Giovanni B, Font, Roser Farré, Fowler, Amy L, Fretwell, Kenneth R, Fructuoso, Lorena Sanchon, Fusai, Giuseppe K, Garcia, Miguel Hernandez, Garcia-Ureña, Miguel Angel, Gill, Charn K, Gisbertz, Suzanne S, Del Giudice, Roberto, Giuffrida, Maria Carmela, Di Giuseppe, Matteo, Gómez, María Fanjul, Guariglia, Claudio A, Hainsworth, Alison J, Hall, Bria J, Hall, James RW, Hammond, John S, Haqqani, Maha H, Harrison, Ewen M, Hazelton, Joshua P, van Heinsbergen, Maarten, Hill, Arnold DK, Hing, Caroline B, Hirji, Sameer A, Ho, Michael WS, Holbrook, Charlotte M, Holme, Thomas J, Hopkins, James C, Hopkinson, David N, Hossain, Fahad S, Hudson, Victoria E, Hughes, Jane L, Hwang, E. Shelley, Ibrahim, Mohamed AH, Isolani, Simone M, Jenkinson, Michael D, Jenny, Hillary E, Jeyaretna, Deva S, Jones, Robert P, Jones, Andrew P, Jonker, Pascal KC, Jönsson, Maria L, Joyce, Doireann P, Kalkwarf, Kyle J, Kamarajah, Sivesh K, El Kassas, Mohamed, Kavanagh, Dara O, Keatley, James M, Khalefa, Mohamed A, Khan, Jim S, Kirmani, Bilal H, Kisiel, Aaron P, Kouris, Spyros Marinos, Kowal, Mikolaj R, Labib, Peter L, Larkin, John O, Lauscher, Johannes C, Leclercq, Wouter KG, Ledesma, Frances SJ, Leite-Moreira, André M, Leung, Elaine YL, Lewis, Sophia E, Lima, Maria João, Lin, Daniel J, Liu, Helen H, Lowery, Aoife J, Lozano, Saida Martel, Luney, Catriona R, Maia, Mariana Magalhães, Mariani, Nicolò M, Marino, Marco V, Marra, Angelo A, Marsh, Christopher L, Martin, Robert CG, McCluney, Simon J, McIntyre, Robert C, Mckay, Siobhan C, McKevitt, Kevin L, Meagher, Ashley D, Mehdi, Mohammad Q, Mehigan, Brian J, Gonzalez-De Miguel, Melania, De Miguel-Ardevines, Maria-Carmen, Mills, Sarah J, Mohan, Helen M, Moir, John AG, Monson, John RT, Monteiro, Joana M, Montella, Maria T, Montesinos, Cristina Soto, Morgom, Marwa M, Moura, Francisco S, Muguerza, Jose M, Murphy, Suzanne H, De Nardi, Paola, Naumann, David N, Neary, Paul C, Neely, David TA, Ng-Kamstra, Joshua S, Ngu, Albert WT, Nguyen, Truong A, Nita, George E, Nunes, Quentin M, Nygaard, Rachel M, O'Meara, Lindsay B, O'Neill, John R, Okafor, Barbara U, Olson, Steven A, Oo, Aung Y, Ormazabal, Pablo Collera, Osorio, Alexander L, Pachl, Max J, Parry, James T, Patel, Panna K, Pérez-Sánchez, Luis E, Pevidal, Ana Nogues, Pezzuto, Anna P, Philp, Matthew M, Pinkney, Thomas D, Pollok, Joerg M, Povey, Meical G, Poza, Alfredo Alonso, Rajgor, Amarkumar D, Rao, Jagan N, Raptis, Dimitri A, Rice, Henry E, Ridgway, Paul F, Rivas, Ana Munoz, Rodriguez-Sanjuan, Juan C, Rogers, Luke J, Da Roit, Anna, Rollett, Rebecca A, Romera, Jose L, Rooney, Siobhan M, Roxo, Vanessa I, Le Roy, Bertrand, Rubio, Eduardo E, Ruiz, Carolina Castro, Ruiz, Manuel Losada, Ryan, Éanna J, Saad, Abdel Rahman, Saeed, Samerah A, Salama, Hiba A, Salamah, Abdulrauf A, Sampietro, Gianluca M, Sarma, Diwakar R, Schaffer, Kathryn B, Schnitzbauer, Andreas A, Scurrah, Rachel J, Serevina, Olivia L, Serralheiro, Pedro A, Sewards, Joseph M, Shackcloth, Michael J, Shaw, Abigail V, Sheel, Andrea RG, Sica, Giuseppe S, De Simone, Veronica, Singh, Aminder A, Singh, Rabindra P, Skelly, Brendan L, Smith, Henry G, Sohail, Amir H, Spalding, Duncan R, Springford, Laurie R, Ssentongo, Anna E, Steinkamp, Pieter J, Stevens, Kent A, Stewart, Grant D, Stylianides, Nicholas A, Sullivan, Tom BB, Taher, Ahmed SA, Tamimy, Muhammad S, Tang, Alethea M, Tebala, Giovanni D, Tejero-Pintor, Francisco J, Thaha, Mohamed A, Thomas, Amy J, De Toma, Giorgio, La Torre, Filippo, Torres, Antonio J, Townshend, David N, Trout, Isobel M, Tucker, Sarah C, Ubhi, Harmony K, Vega, Viviana A, Velmahos, George C, Velopulos, Catherine G, Viswanath, Yirupaiahgari KS, Vivas, Alfredo A, Wade, Ryckie G, Wadley, Martin S, Wall, Joshua JS, Walters, Andrew M, Warren, Oliver J, Weerasinghe, Chamindri K, Wilkin, Richard JW, Williams, Katherine J, Winter, Stuart C, Wormald, Justin CR, Wright, Franklin L, Xyda, Souzana E, Young, Alastair L, Youssef, Mina MG, Yousuf, Farhat B, El Youzouri, Hanan, Zappa, Marco A, Abate, Emmanuele, Abdalaziz, Hossam, Abdelkarim, Mostafa, Abdou, Hossam, Aboelkassem-Ibrahim, Ahmad, Abuown, Ala, Acebes-Garcia, Fernando, Acharya, Metesh, Adamina, Michel, Addae-Boateng, Emmanuel, Aftab, Raiyyan, Agarwal, Arnav, Aguilar, José, Ahmed, Yousra, Aitken, Emma, Al-Azzawi, Marwa, Al-Embideen, Somya, Al-Masri, Mahmoud, Al-Najjar, Hani, Al-Sukaini, Ahmad, Alam, Ruhina, Alderson, Derek, Aliyeva, Zumrud, Aljanadi, Firas, Almasri, Murad, Alonso-Ortuño, Paula, Altintoprak, Fatih, Amira, Gamal, Amjad, Rabbia, Anania, Gabriele, Andabaka, Tatjana, Angelou, Dimitrios, Annamalai, Seethalakshmi, Annessi, Valerio, Anthoney, James, Anwar, Sibtain, Anwer, Mariyah, Aragon-Chamizo, Juan, Ardito, Antonella, Arigoni, Michele, Armao, Teodora, Arminio, Armando, Armstrong, Lara, Arnaud, Alexis, Asaad, Peter, Ashcroft, James, Ashmore, Christopher, Asqalan, Ahmad, Asti, Emanuele, Aubry, Emmanuelle, Aytac, Erman, Ayuso-Herrera, Esther, Baeza, Melody, Bailon-Cuadrado, Martin, Bakmaz, Bernarda, Baldi, Caterina, Baldini, Edoardo, Baldo, Stefano, Ballabio, Michele, Baloyiannis, Ioannis, Baltazar, Gerard, Bàmbina, Fabrizio, Bandiera, Alessandro, Barlow, Emma, Barmasse, Roberto, Barmpagianni, Christina, Baronio, Gianluca, Barra, Fabio, Bartsch, Anne-Marie, Basgaran, Amedra, Basha, Amr, Bashkirova, Varvara, Bastazza, Marco, Baumber, Rachel, Belcher, Elizabeth, Belvedere, Angela, Benítez-Linero, Inmaculada, Bergeat, Damien, Bernasconi, Matteo, Bhalla, Ashish, Bhutiani, Neal, Bianco, Federica, Bisagni, Pietro, Blake, Iain, Blanco-Colino, Ruth, Blazquez-Martin, Alma, Boal, Matthew, Bonavina, Luigi, Bonavina, Giulia, Bond-Smith, Giles, Booth, Karen, Borges, Filipe, Borghi, Felice, Bouchagier, Konstantinos, Bourke, Grainne, Boyle, Emily, Brachini, Gioia, Brain, Jessie, Brar, Amanpreet, Breckles, Lisa, Bretagnol, Frédéric, Brixton, Genevieve, Bruzzaniti, Placido, Bueser, Teofila, Burnside, Nathan, Caballero, Albert, Calcerrada-Alises, Enrique, Callahan, Miriam, Camarero, Enrique, Campagnaro, Tommaso, Campanelli, Michela, Candiani, Massimo, Cantalejo-Diaz, Miguel, Cao, Han, Capelli, Patrizio, Capizzi, Vita, Carcano, Giulio, Carissimi, Francesca, Carlini, Massimo, Carlucci, Michele, Carmichael, Heather, Carrasco, Milagros, Carrillo, Mariana, Carvello, Michele, Casati, Massimiliano, Castoro, Carlo, Catalan, Vanesa, Cavaleiro, Salomé, Cellerino, Paola, Centinaio, Giovanna, Cernei, Cristina, Cerro, Cristina, Cervellera, Maurizio, Chakrabortee, Sohini, Chamberlain, Stephanie, Chan, Jeffrey, Chang, Grace, Chaudhry, Dauod, Chebaro, Alexandre, Chen, David, Chetty, Govind, Chia, Zoe, Chiappini, Ambra, Chiarugi, Massimo, Chidambaram, Swathikan, Chiozza, Matteo, Cholewa, Hanna, Chong, Clara, Choolani-Bhojwani, Ekta, Christoforidis, Dimitri, Chui, Karen, Chung, Choyin, Cirillo, Bruno, Citterio, Davide, Clermidi, Pauline, Coccolini, Federico, Colletti, Gaia, Compagnoni, Bruno, Concepción-Martín, Vanesa, Confalonieri, Marco, Connolly, Hannah, Conso, Christel, Conti, Luigi, Cooper, Zara, Cordera, Fernando, Corral, Javier, Costa, Marta, Costanzi, Andrea, Cotsoglou, Christian, Cozza, Valerio, Cuming, Tamzin, Curtis, Miles, Cuschieri, Joseph, D'Agruma, Michele, D'Andrea, Giancarlo, Daliya, Prita, Dare, Oliver, Darko, Ebenezer, Day, Andrew, Dehal, Ahmed, Dehart, Dustin, Delgado-Oliver, Eduardo, Denning, Max, Desai, Anant, Desender, Liesbeth, Dester, Sara, Díaz-García, Alberto, Diaz-Peña, Patricia, Dousset, Bertrand, Doussot, Alexandre, Duchateau, Nicolas, Duff, Sarah, Dunning, Joel, Duque-Mallen, Victoria, Dziakova, Jana, Egan, Bridget, Egan, Richard, El-Ali, Abess, Elfeki, Hossam, Elhadi, Muhammed, Eljareh, Mohammed, Elkady, Ramy, Elkhafeefi, Fatimah, Elmore, Ugo, Elmoslemany, Tarek, Emmerson, Oliver, Enemosah, Ibrahim, English, Camilla, English, William, Escartin, Jorge, Estaire-Gomez, Mercedes, Evans, Luke, Evans, Jessica, Exley, Rebecca, Fabbri, Nicoló, Falco, Giuseppe, Familiari, Pietro, Fancellu, Alessandro, Farik, Shebani, Farrell, Tony, Fehervari, Matyas, Fell, Adam, Fernandez-Camuñas, Angel, Fernández-Marín, Reyes, Fernández-Martínez, María, Ferrara, Francesco, Ferrari, Guglielmo, Ferrero, Simone, Findlay, Laura, Fiore, Marco, Fiori, Enrico, Flatman, Michael, Flindall, Ian, Flor, Blas, Fontana, Tommaso, Ford, Samuel, Ford, David, Forlani, Stefano, Francone, Elisa, Frattaruolo, Colomba, Frio, Federico, Gagliano, Annalisa, Gagliardi, Filippo, Gahunia, Sukhpreet, Gaino, Francesca, Gala, Tanzeela, Galfrascoli, Elisa, Galimberti, Luca, Gallagher, Phoebe, Galleano, Raffaele, Galván-Pérez, Armando, Gammeri, Emanuele, Ganau, Mario, Garcés-García, Raúl, Garulli, Gianluca, Gascon-Ferrer, Isabel, Gattolin, Andrea, Gaujoux, Sebastien, Gentilli, Sergio, Georgiades, Fanourios, Ghanbari, Amir, Ghosh, Dhruv, Giacometti, Marco, Giblin, Anna-Victoria, Gilbert, Catherine, Giménez, Clara, Giorgakis, Emmanouil, Gipponi, Manuel, Glen, Paul, Goatly, Giles, Gobatti, Davide, Godbole, Chintamani, Gohil, Kajal, Gómez, Marcos, Gomez-Rosado, Juan-Carlos, Gonullu, Emre, Gonzalez-Gonzalez, Enrique, Gordini, Luca, Gracia, Isabel, Gracia-Roche, Carlos, Granieri, Stefano, Green, Susanna, Grivon, Manuela, Grove, Thomas, Guaglio, Marcello, Guaitoli, Eleonora, Guglielmi, Alfredo, Guha, Soumya, Gustavino, Claudio, Habeeb, Amir, Hagger, Robert, Hakmi, Hazim, Halkias, Constantine, Hall, Claire, Hampton, Matthew, Handa, Siddhartha, Hansen, Laura, Haq, Iram, Harky, Amer, Harries, Rhiannon, Harrison, Joseph, Hasan, Raashad, Hawari, Mohammad, Hawkin, Paul, Hebblethwaite, Bethany, Henriques, Susana, Heritage, Emily, Hernandez-Juara, Pilar, Herrero-Lopez, Maria, Hervieux, Erik, Heyd, Bruno, Higgs, Simon, Hitchman, Louise, Ho, Beatrice, Hogan, Aisling, Hölzle, Frank, Hossain, Tanvir, Hurt, Libor, Hutchinson, Peter, Iacob, Giulio, Iannone, Immacolata, Ibrahim, Sherif, Iovino, Domenico, Isik, Arda, Jafarova, Sevda, Jamil, Tahir, Jayaraju, Ullas, Jenner, Edward, Jimenez-Higuera, Elisa, Jimeno, Jaime, Jones, Mark, Judkins, Nicholas, Kalavrezos, Nicholas, Kalidindi, Venugopala, Kalkat, Maninder, Kamal, Mona, Kamphues, Carsten, Kang, Chong, Kara, Yasin, Karam, Edward, Karim, Ahmed, Kashora, Florence, Kearney, David, Khajuria, Apoorva, Khan, Umul, Khan, Azam, Khatri, Chetan, Kinnaman, Gabriel, Kinross, James, Kler, Aaron, Klimopoulos, Serafeim, Kocataş, Ali, Kolias, Angelos, Königsrainer, Alfred, Konsten, Joop, Kontovounisios, Christos, Kourdouli, Amar, Krishnan, Emily, Kristinsson, Sverrir, Kruijff, Schelto, Kudsk-Iversen, Søren, Kufeji, Dorothy, Kugler, Nadav, Kulkarni, Rugved, Kurihara, Hayato, Laface, Letizia, Lakkis, Zaher, Lami, Mariam, Landaluce-Olavarria, Aitor, Lapolla, Pierfrancesco, Lawani, Ismail, Lawday, Samuel, Lázaro, André, Lecolle, Katia, Leventoglu, Sezai, Li, Zoe, Liew, Ignatius, Lisi, Giorgio, Lizzi, Vincenzo, Lo, Terence, Lomiento, Daniele, Longhi, Marco, Lostis, Emilie, Lostoridis, Eftychios, Loubani, Mahmoud, Lowy-Benoliel, Alejandro, Lucianetti, Alessandro, Luke, Louis, Lunevicius, Raimundas, Luraghi, Marco, Lye, George, Mabrouk, Islam, Macchi, Alberto, MacDonald, Luisa, Machairas, Nikolaos, Madonini, Marco, Magowan, Drew, Maisonneuve, Emeline, Majkowska, Agata, Majkowski, Lawrence, Mak, Jason, Malabarba, Stefano, Malerba, Michele, Mannan, Syed, Manson, Joanna, Mansuri, Ahmer, Mantoglu, Baris, Manu, Nichola, Maqsood, Afnan, Marano, Alessandra, Marchbank, Adrian, Marcos-Santos, Pablo, Marrano, Enrico, Martin, Janet, Martin, Emmeline, Martin, Guy, Martin-Albo, Lorena, Martín-Román, Lorena, Martinelli, Fabio, Martínez-dePaz, Fernando, Martinez-German, Antonio, Martinez-Pinedo, Carlos, Martins, Ricardo, Marwan, Hisham, Marzi, Federica, Mathieu, Pierre, Matute-Najarro, Maria-Soledad, Maw, Andrew, Mazingi, Dennis, Mazzaferro, Vincenzo, McCanny, Andrew, McKenzie, Katherine, McLarty, Nicola, McPherson, Iain, Medina, Esther, Mediratta, Saniya, Medone, Marzia, Mehra, Gautam, Mele, Simone, Melero-Cortés, Lidia, Mendoza-Moreno, Fernando, Meneghini, Simona, Mercante, Giuseppe, Merdrignac, Aude, Merola, Stephen, Metallidis, Symeon, Michel, Martin, Migliore, Marco, Mihanovic, Jakov, Miller, Douglas, Mingoli, Andrea, Minto, Gary, Mirabella, Antonello, Misra, Nikhil, Mitrasinovic, Stefan, Miu, Victor, Moawad, Nader, Mochet, Sylvie, Modabber, Ali, Mohammad, Adam, Mohan, Midhun, Moliner-Sánchez, Carmen, Mongelli, Francesco, Monteleone, Michela, Montuori, Mauro, Moore, Rachel, Mora-Guzmán, Ismael, Morales, Xavier, Morales, Dieter, Morelli, Luca, Morelli, Lucia, Morgan, Richard, Morris, Chris, Mortini, Pietro, Mosca, Angelo, Motter, Dema, Moug, Susan, Mukherjee, Samrat, Najdy, Manhal, Nakas, Apostolos, Namazov, Ilgar, Naredla, Pradyumna, Nasef, Emmhamed, Nassa, Heeam, Nath, Rahul, Navarro-Sánchez, Antonio, Nazarian, Scarlet, Negri, Giampiero, Nehra, Deepika, Neil-Dwyer, Jason, Neri, Jacopo, Newton, Katy, Nikaj, Herald, Niquen, Milagros, Nobile, Sara, Nogueiro, Jorge, Ntirenganya, Faustin, Nugent, Michael, Núñez, Jordi, Ocaña, Juan, Okechukwu, Valentine, Oliva-Mompean, Fernando, Oliveira, Ana, Ollat, Didier, Onos, Lavinia, Osagie-Clouard, Liza, Osman, Khabab, Ottolina, Jessica, Ourieff, Jared, Outani, Oumaima, Oyewole, Bankole, Ozben, Volkan, Pacheco-Sanchez, David, Padilla-Valverde, David, Pai, Madhava, Paiella, Salvatore, Paisley, Samuel, Palini, Gianmarco, Palmeri, Matteo, Panahi, Pedram, Parente, Alessandro, Parlanti, Daniele, Parmar, Chetan, Pascual, Angela, Patel, Mahul, Pathak, Abhijit, Patil, Sangram, Pattyn, Piet, Peckham-Cooper, Adam, Pedrazzani, Corrado, Pellino, Gianluca, Peluso, Chiara, Pereira, André, Pereira-Neves, António, Perez-Diaz, MD, Pérez-González, Marta, Pérez-Saborido, Baltasar, Perivoliotis, Konstantinos, Perkins, Clare, Peros, Georgios, Perotto, Ornella, Perra, Teresa, Petrone, Patrizio, Phenix, George, Picazo, Sara, Picon-Rodriguez, Rafael, Piloni, Martina, Pingarrón-Martín, Lorena, Pinotti, Enrico, Pisanu, Adolfo, Pizzini, Paolo, Pockney, Peter, Podda, Mauro, Podolsky, Dina, Poggioli, Gilberto, Pompili, Cecilia, Pontari, Michael, Porcu, Alberto, Potter, Ryan, Price, Claire, Pruvot, François-René, Pujol-Muncunill, Roger, Puppo, Andrea, Quante, Markus, Quintana-Villamandos, Begoña, Qureshi, Ali, Radenkovic, Dejan, Rakvin, Ivan, Ramallo-Solís, Irene, Ramcharan, Sean, Ramos, Diego, Ramos-Bonilla, Antonio, Ramzi, Joussi, Rathinam, Sridhar, Rausa, Emanuele, Ravaioli, Matteo, Ravindran, Sharanya, Raymond, Thomas, Razik, Aisha, Redfern, Jennifer, Reguera-Rosal, Julio, Rela, Mariam, Rey-Biel, Juan, Rey-Valcarcel, Cristina, Ribolla, Marta, Richards, Tomos, Richmond, Michael, Righini, Erminio, Rio-Gomez, Javier, Riyat, Harjoat, Rizvi, Sana, Roberts, Keith, Roberts, Matthew, Robertson, Stuart, Robertson, Ronald, Robin-Valle, Alvaro, Rochon, Melissa, Rojo, Mikel, Rolli, Luigi, Romano, Silvio, Ross, Elizabeth, Ross, Howard, Rossborough, Catherine, Rottoli, Matteo, Ruiz-Grande, Fernando, Ruiz-Martin, Irene, Ruiz-Soriano, María, Ruzzenente, Andrea, Ryska, Ondrej, Saez, Carlos, Sagnotta, Andrea, Sahnan, Kapil, Sahni, Arun, Salim, Ali, Sallam, Ibrahim, Salvia, Roberto, Samadov, Elgun, Sammarco, Giuseppe, Sampaio-Alves, Mafalda, Sánchez-Arteaga, Alejandro, Sanchez-Fuentes, Maria-Nieves, Sanchez-Pelaez, Daniel, Sanchez-Perez, Coral, Sanchez-Rubio, Maria, Sancho-Muriel, Jorge, Sanders, Julie, Santero-Ramirez, Maria-Pilar, Santora, Thomas, Santoro, Antonio, Santos, Irene, Santos-Sousa, Hugo, Sapienza, Paolo, Sartarelli, Lodovico, Sarveswaran, Janahan, Sasia, Diego, Saudemont, Alain, Saudi-Moro, Sef, Saxena, Shobhit, Saxena, Dolly, Sayasneh, Ahmad, Scalabre, Aurelien, Schache, Andrew, Schiavina, Riccardo, Schineis, Christian, Schreckenbach, Teresa, Scorza, Antonella, Scott, Lucy, Seegert, Sara, Seguin-Givelet, Agathe, Senent-Boza, Ana, Seymour, Keith, Shabana, Amanda, Shah, Karishma, Shah, Jigar, Shah, Preena, Shah, Sujay, Shakir, Taner, Shalaby, Mostafa, Shankar, Sushma, Shaw, Richard, Shehata, Sameh, Shenfine, Amy, Sheridan, Kelda, Sherief, Ahmed, Sherief, Mohamed, Sherif, Mohamed, Shinkwin, Michael, Shu, Sebastian, Siaw-Acheampong, Kwabena, Sileri, Pierpaolo, Singh, Abhinav, Singh, Shailendra, Sinha, Sanjay, Sinha, Deepti, Siragusa, Leandro, Sivaprakasam, Rajesh, Sivayoganathan, Sriharan, Smillie, Robert, Smith, Claire, Smith, Andrew, Smith, Christopher, Sochorova, Dana, Soggiu, Fiammetta, Sohrabi, Catrin, Solari, Francesca, Solli, Piergiorgio, Soreide, Kjetil, Spinelli, Antonino, Spoletini, Domenico, Spriano, Giuseppe, Sravanam, Sanskrithi, Ssentongo, Paddy, Stanger, Sophie, Stavroulias, Dionisios, Steel, Ben, Stella, Marco, Stewart, Robbie, Stringer, Sally, Sulen, Nina, Sundar, Sudha, Sundhu, Matthew, Suri, Avni, Syed, Arooj, Szatmary, Peter, Tabiri, Stephen, Tadross, Daniel, Taglietti, Lucio, Tansey, Rosamond, Tartaglia, Dario, Tawheed, Ahmed, Tayeh, Salim, Teles, Tobias, Testa, Valentina, Tewari, Nilanjana, Thoenissen, Philipp, Thomas, Kane, Thomin, Anne, Thrush, Jessica, Tierney, Sean, Tiwari, Abhinav, Toh, Simon, Toledo, Enrique, Tonini, Valeria, Torkington, Jared, Torquati, Alfonso, Torzilli, Guido, Totty, Joshua, Tourountzi, Paraskevi, Tousidonis, Manuel, Townend, Philip, Townsend, Catherine, Trompeter, Alex, Trotta, Francesco, Truant, Stéphanie, Trujillo-Díaz, Jeancarlos, Tsoulfas, Georgios, Turco, Celia, Turrado-Rodriguez, Victor, Turri, Giulia, Tustin, Harry, Tyler, Jayne, Tzedakis, Stylianos, Tzovaras, George, Uittenbogaart, Martine, Ullah, Ramzan, Urban, Shane, Urbani, Alessia, Usai, Antonella, Vaccarella, Gianpaolo, Valdes-Hernandez, Javier, Valsecchi, Luca, Vashisht, Rajiv, Vázquez-Fernández, Andrea, Venn, Mary, Vera-Mansilla, Cristina, Vergari, Roberto, Vescio, Giuseppina, Vidya, Raghavan, Vieira, Paula, Vijay, Vardhini, Vimalachandran, Dale, Violante, Tommaso, Volpe, Anita, Vovola, Fernanda, Vulliamy, Paul, Wall, Rosemary, Wallwork, Kate, Ward, Alex, Warwick, David, Waseem, Saima, Weaver, Helen, Wells, Fiona, Wen, Jiaxin, West, Raha, Whitehall, Emma, Wild, Laura, Wilkins, Alex, Williams, Gethin, Williams, Matthew, Winnand, Philipp, Wong, Ken, Worku, Dawit, Wright, Naomi, Yalamanchili, Seema, Yershov, Danylo, Yildiz, Alp, Young, Richard, Yurttas, Can, Zadegan, Frederic, Zafar, Noman, Zakaria, Rasheed, Zambon, Martina, Zanini, Nicola, Zarate, Alba, Zerbib, Philippe, Zizzo, Maurizio, Zmora, Oded, Zonta, Sandro, van Berge Henegouwen, Mark I, van der Plas, Willemijn Y, Ali, Inthekab Ali Mohamed, Bakri, Nur Amalina Che, Bauset, Juan Carlos Catalá, Abou Chaar, Mohamad K, Marino Cosentino, Luigi MP, Gómez Díaz, Carlos J, Garcia Galocha, Jose L, de Gheldere, Charles A, Ataíde Gomes, Gustavo Mendonça, Beltrán de Heredia, Juan, Blazer III, Dan G, Nugent III, William C, Ali karar, Ali A, Borja De Lacy, F, Blas Laina, Juan luis, Shane Lester, Madan Jha, Liyanage, Aloka S D, Al Maadany, Faraj S, De Marchi, Joshua A, Ramos-De la Medina, Antonio, Mithany, Reda H M, Sanchez del Pueblo, Cristina, van Ramshorst, Gabrielle H, De Salas, Maria Marqueta, De Souza, Anthony C, Dolores Del Toro, M, Archer, James E, Odeh, Abdulrahman, Erridge, Simon, Salem, Hosni Khairy, Jones, Gareth P, Gardner, Anne, Tripathi, Shiva S, Gregg, Anne, Jeganathan, Reuben, Siddique, Muhammad Harris, Lombardi, Celestino P, Martin, Benjamin, Leo, Cosimo Alex, Dass, Debashis, Di Franco, Gregorio, Jiao, Long R, Mari, Giulio Maria, Capitan-Morales, Luis-Cristobal, Connelly, Tara M, Alanbuki, Ammar, De Virgilio, Armando, Schilling, Clare, San Miguel Mendez, Carlos, Kulkarni, Gauri, Nizami, Kulsoom, Walsh, Stewart, Dean, Harry, Ruiz-Marin, Miguel, Houston, Rory, Trompetto, Mario, Chrastek, David, Kouritas, Vasileios, Cannoletta, Maria, Rosato, Francesco, Kaushal, Manish V, Costa, Paulo Matos, Elkadi, Hannah H, Johnstone, Jack R, Irvine, Esmee, Alvarez, Maria R, Corbellini, Carlo, Venkatesan, Gowtham S, Mateo-Sierra, Olga, Martínez-Pérez, Carolina, Serrano González, Javier, Hernández Bartolomé, Miguel Ángel, Díaz Pérez, David, Gutiérrez Samaniego, María, Galindo Jara, Pablo, Sharma, Neil, Smart, Neil J, and Keller, Deborah S

Published
2020
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8. Serological responses to the BNT-162b2 Pfizer/BioNTech vaccination in twin pregnancies- Comparison between immunization before conception and during pregnancy.

Author

Svirsky, Ran, primary, Rabbi, Moran Landau, additional, Hamad, Ramzia Abu, additional, Sharabi-Nov, Adi, additional, Kugler, Nadav, additional, Galoyan, Narina, additional, Sharon, Nataly Zilberman, additional, Meiri, Hamutal, additional, Maymon, Ron, additional, and Zion, Osnat Korach-Lev, additional

Published
2023
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11. Oligohydramnios: how severe is severe?

Author

Sharon, Nataly Zilberman, Pekar-Zlotin, Marina, Kugler, Nadav, Accart, Zohar, Nimrodi, Maya, Melcer, Yaakov, Cuckle, Howard, and Maymon, Ron

Subjects
POLYHYDRAMNIOS, FETAL monitoring, AMNIOTIC liquid, MEDICAL centers, EXPERIMENTAL design, PREGNANCY
Abstract

Objective: To investigate whether the severity of isolated oligohydramnios at term is associated with increased rates of adverse perinatal outcome. Study design: A retrospective study conducted in a single medical center from 2017 to 2019. All low-risk pregnancies with incidental isolated oligohydramnios at term were included. The degree of oligohydramnios was arbitrarily classified into mild (AFI = 41–50 mm), moderate (AFI = 21–40 mm) and severe (AFI = 0–20 mm). Result: A total of 610 women were included: 202 with a mild (33.1%), 287 moderate (47.0%), and 121 severe oligohydramnios (19.8%). Non-reassuring monitor requiring immediate delivery and worse composite neonatal outcome were more common among severe than mild or moderate oligohydramnios (14.0% and 6.4%, 7.3% respectively; p = .039 and 19.8%, 10.9% and 11.8%, respectively; p = .048). Conclusion: Low-risk pregnancies with isolated severe oligohydramnios at term have a higher tendency toward non-reassuring fetal monitoring requiring prompt delivery and adverse neonatal outcomes, this calls for close intrapartum surveillance [ABSTRACT FROM AUTHOR]

Published
2022
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12. Comparison between a prenatal sonographic scoring system and a clinical grading at delivery for Placenta Accreta Spectrum disorders.

Author

Pekar-Zlotin, Marina, Maymon, Ron, Revivo, Perry Eliassi, Ezratty, Jody, Melcer, Yaakov, Kugler, Nadav, and Jauniaux, Eric

Subjects
PLACENTA accreta, PLACENTA praevia, CESAREAN section, MEDICAL screening, DELIVERY (Obstetrics), CLINICAL pathology
Abstract

Objective Placenta Accreta Spectrum (PAS) disorders have become a major iatrogenic obstetric complication worldwide. Data on the accuracy of ultrasound examination diagnosis are limited by incomplete confirmation and variability in the description of the different grades of PAS at delivery. The aim of this study was to compare our prenatal routine sonographic screening and diagnostic scoring system with a standardized clinical grading system at birth in patient at risk of PAS Study design This is a retrospective cohort study of 607 pregnant patients with at least one prior cesarean delivery between December 2013 and December 2018. All patients were assessed for PAS using our institutional prenatal sonographic scoring system and the corresponding ultrasound findings were compared with those of a standardized clinical intra-operative macroscopic grading system of the degree of accreta placentation at vaginal birth or laparotomy. Results PAS was diagnosed clinically at birth in 50 (8.2%) cases, 17 of which were confirmed by histopathology. A low (score ≤ 5), medium (score 6-7), high (score ≥ 8) probability for PAS was reported in 502, 61 and 44 cases, respectively. The probability score increased significantly (p < .001) in women ≥2 prior cesarean deliveries, with an anterior low-lying/placenta previa, with absent clear space, increased in retroplacental vascularity and with the size and numbers of lacunae. The number of cases classified clinically as grade 1 (non-PAS) and 3 (adherent PAS) was significantly (p < .001) lower in women with a high probability score whereas the rates of the other grades was significantly (p < .001) higher. The widest discrepancy between ultrasound probability score and clinical grade was found for grade 2 which, describes a partial placental adherence and grades 4 and 5 which, refer to placental percreta which describes tissue having invade trough the uterine serosa and beyond. Conclusions Both ends of the spectrum of accreta placentation remain difficult to diagnose antenatal and clinically at birth, in particular when no histopathologic confirmation is available. There is a need to develop ultrasound accuracy score systems that can differentiate between the different grades of PAS and which are validated by standardized clinical and pathology protocols. [ABSTRACT FROM AUTHOR]

Published
2022
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13. Oligohydramnios: how severe is severe?

Author

Zilberman Sharon, Nataly, primary, Pekar-Zlotin, Marina, additional, Kugler, Nadav, additional, Accart, Zohar, additional, Nimrodi, Maya, additional, Melcer, Yaakov, additional, Cuckle, Howard, additional, and Maymon, Ron, additional

Published
2021
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17. Pre-Twin Screen - A Multi-Disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Author

Nicolaides Kypros, Geipel Annegret, Strizek Brigitte, Goncé Anna, Kugler Nadav, Bennasar Mar, Svirsky Ran, Kagan Oliver, Cuckle Howard, Meiri Hamutal, Maymon Ron, Brown Richard Nicolas, Miron Piere, Syngeleki Argyro, and Borrell Antoni

Subjects
medicine.medical_specialty, Multi disciplinary, business.industry, medicine, Medical physics, business
Published
2020
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18. Impact of the COVID-19 Pandemic on Excess Perinatal Mortality and Morbidity in Israel.

Author

Mor, Matan, Kugler, Nadav, Jauniaux, Eric, Betser, Moshe, Wiener, Yifat, Cuckle, Howard, and Maymon, Ron

Subjects
*PERINATAL death & psychology, *HEALTH policy, *DISEASES, *RETROSPECTIVE studies, *PATIENTS, *FEAR, *PREGNANCY outcomes, *HOSPITAL admission & discharge, *DESCRIPTIVE statistics, *INFANT mortality, *OBSTETRICAL emergencies, *COVID-19 pandemic, *LONGITUDINAL method
Abstract

Objective  The 2020 COVID-19 pandemic has been associated with excess mortality and morbidity in adults and teenagers over 14 years of age, but there is still limited evidence on the direct and indirect impact of the pandemic on pregnancy. We aimed to evaluate the effect of the first wave of the COVID-19 pandemic on obstetrical emergency attendance in a low-risk population and the corresponding perinatal outcomes. Study Design  This is a single center retrospective cohort study of all singleton births between February 21 and April 30. Prenatal emergency labor ward admission numbers and obstetric outcomes during the peak of the first COVID-19 pandemic of 2020 in Israel were compared with the combined corresponding periods for the years 2017 to 2019. Results  During the 2020 COVID-19 pandemic, the mean number of prenatal emergency labor ward admissions was lower, both by daily count and per woman, in comparison to the combined matching periods in 2017, 2018, and 2019 (48.6 ± 12.2 vs. 57.8 ± 14.4, p  < 0.0001 and 1.74 ± 1.1 vs. 1.92 ± 1.2, p  < 0.0001, respectively). A significantly (p  = 0.0370) higher rate of stillbirth was noted in the study group (0.4%) compared with the control group (0.1%). All study group patients were negative for COVID-19. Gestational age at delivery, rates of premature delivery at <28, 34, and 37 weeks, pregnancy complications, postdate delivery at >40 and 41 weeks, mode of delivery, and numbers of emergency cesarean deliveries were similar in both groups. There was no difference in the intrapartum fetal death rate between the groups. Conclusion  The COVID-19 pandemic stay-at-home policy combined with patient fear of contracting the disease in hospital could explain the associated higher rate of stillbirth. This collateral perinatal damage follows a decreased in prenatal emergency labor ward admissions during the first wave of COVID-19 in Israel. Key Points Less obstetrical ER attendance is observed during the pandemic. There is a parallel increase in stillbirth rate. Stillbirth cases tested negative for COVID-19. Lockdown and pandemic panic are possible causes. [ABSTRACT FROM AUTHOR]

Published
2021
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19. Second‐trimester and early third‐trimester spontaneous uterine rupture: A 32‐year single‐center survey.

Author

Maymon, Ron, Mor, Matan, Betser, Moshe, Kugler, Nadav, Vaknin, Zvi, Pekar‐Zlotin, Marina, and Melcer, Yaakov

Subjects
PRENATAL diagnosis, ACQUISITION of data methodology, THIRD trimester of pregnancy, TERTIARY care, PREGNANCY outcomes, CHILD health services, MEDICAL records, DESCRIPTIVE statistics, PREGNANCY complications, SECOND trimester of pregnancy, CESAREAN section, UTERINE rupture, HEALTH promotion, SYMPTOMS, PREGNANCY
Abstract

Background: Second‐trimester and early third‐trimester uterine rupture in a nonlaboring woman is a very rare and life‐threatening condition for both mothers and newborns. We aimed to present clinical characteristics, prenatal findings, and maternal and neonatal outcomes following second‐trimester and early third‐trimester spontaneous antepartum uterine rupture in our institute. Method: The medical records of all women with full‐thickness second‐trimester and early third‐trimester uterine rupture treated in our department from 1988 to 2019 were retrieved from the institutional database and reviewed. Small uterine defects, incomplete ruptures, and silent uterine incision dehiscence were excluded. Results: From 1988 to 2019, 213 665 deliveries were recorded in our institute. Of these, 12 patients experienced second‐trimester or early third‐trimester spontaneous uterine rupture. Obstetric history revealed that 50% of the women in each period had undergone previous classical uterine incisions and 50% had a short interpregnancy (IP) interval. The mean age at diagnosis of uterine rupture was 26.3 ± 5.1 weeks. The ruptures were associated with abnormal placentation in 10 cases (83.3%): placenta previa (n = 7); and placenta previa and percreta (n = 3). No maternal mortality occurred. Seven of the 10 (70%) viable newborns survived. Conclusions: The increasing rates of cesarean births (CB) may lead to iatrogenic complications including midgestational prelabor spontaneous uterine rupture, an obstetric emergency, which is hard to diagnose. Maternal and neonatal outcomes can be optimized by a greater awareness of the risk factors, recognition of clinical signs and symptoms, and the availability of ultrasound to assist in establishing a diagnosis to enable prompt surgical intervention. [ABSTRACT FROM AUTHOR]

Published
2021
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20. Impact of the Israeli Ministry of Health Cytomegalovirus Guidelines on the Local Pregnancy Outcome.

Author

Pekar-Zlotin, Marina, Alufi Naim, Anat, Eliassi Revivo, Perry, Kugler, Nadav, Melcer, Yaakov, Wiener, Yifat, and Maymon, Ron

Subjects
PREGNANCY outcomes, ABORTION, AMNIOCENTESIS, PREGNANT women, CYTOMEGALOVIRUS diseases, CYTOMEGALOVIRUSES, COMMUNICABLE disease epidemiology, RETROSPECTIVE studies, PREGNANCY complications
Abstract

Objective: In 2011, the Israeli Ministry of Health (MOH) published standard guidelines for the follow-up of pregnant women infected by CMV, recommending that amniocentesis be performed in cases of maternal serum viral seroconversion or abnormal sonographic findings suggestive of CMV, in order to prove fetal infection before electing for pregnancy termination.Methods: A retrospective cohort study was performed, describing 448 pregnant women from 2006 to 2017. We collected data from all women that elected to continue their pregnancies after seroconversion and also of those who chose to undergo pregnancy termination. Subsequently, a telephone survey was then conducted to record outcomes of the newborns of women with CMV seroconversion during pregnancy.Results: 325 (73%) women chose to continue their pregnancy, while 123 (27%) opted for termination of pregnancy. We found that pregnancy termination due to CMV infection was reduced by 7%, from 72 cases (32%) to 51 cases (25%) after the implementation of the MOH guidelines in 2011. In addition, 182/305 (60%) of women responded to our telephone questionnaire regarding newborn outcomes. Of these women, 45/305 (14%) reported complications, and no correlation was found between the prenatal findings and postnatal outcome among those who have responded to our survey.Conclusion: Implementation of the new MOH guidelines has reduced the rate of pregnancy termination, without increasing the rate of neonatal complications in Israel with a similar outcome of complication rate as reported in the literature. [ABSTRACT FROM AUTHOR]

Published
2021
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21. Oligohydramnios: how severe is severe?

Author

Zilberman Sharon N, Pekar-Zlotin M, Kugler N, Accart Z, Nimrodi M, Melcer Y, Cuckle H, and Maymon R

Subjects
Pregnancy, Infant, Newborn, Female, Humans, Retrospective Studies, Amniotic Fluid, Pregnancy Outcome epidemiology, Fetal Monitoring, Oligohydramnios epidemiology
Abstract

Objective: To investigate whether the severity of isolated oligohydramnios at term is associated with increased rates of adverse perinatal outcome., Study Design: A retrospective study conducted in a single medical center from 2017 to 2019. All low-risk pregnancies with incidental isolated oligohydramnios at term were included. The degree of oligohydramnios was arbitrarily classified into mild (AFI = 41-50 mm), moderate (AFI = 21-40 mm) and severe (AFI = 0-20 mm)., Result: A total of 610 women were included: 202 with a mild (33.1%), 287 moderate (47.0%), and 121 severe oligohydramnios (19.8%). Non-reassuring monitor requiring immediate delivery and worse composite neonatal outcome were more common among severe than mild or moderate oligohydramnios (14.0% and 6.4%, 7.3% respectively; p  = .039 and 19.8%, 10.9% and 11.8%, respectively; p  = .048)., Conclusion: Low-risk pregnancies with isolated severe oligohydramnios at term have a higher tendency toward non-reassuring fetal monitoring requiring prompt delivery and adverse neonatal outcomes, this calls for close intrapartum surveillance.

Published
2022
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22. Second-trimester and early third-trimester spontaneous uterine rupture: A 32-year single-center survey.

Author

Maymon R, Mor M, Betser M, Kugler N, Vaknin Z, Pekar-Zlotin M, and Melcer Y

Subjects
Cesarean Section, Female, Humans, Infant, Newborn, Pregnancy, Pregnancy Trimester, Second, Pregnancy Trimester, Third, Uterine Rupture epidemiology, Uterine Rupture etiology
Abstract

Background: Second-trimester and early third-trimester uterine rupture in a nonlaboring woman is a very rare and life-threatening condition for both mothers and newborns. We aimed to present clinical characteristics, prenatal findings, and maternal and neonatal outcomes following second-trimester and early third-trimester spontaneous antepartum uterine rupture in our institute., Method: The medical records of all women with full-thickness second-trimester and early third-trimester uterine rupture treated in our department from 1988 to 2019 were retrieved from the institutional database and reviewed. Small uterine defects, incomplete ruptures, and silent uterine incision dehiscence were excluded., Results: From 1988 to 2019, 213 665 deliveries were recorded in our institute. Of these, 12 patients experienced second-trimester or early third-trimester spontaneous uterine rupture. Obstetric history revealed that 50% of the women in each period had undergone previous classical uterine incisions and 50% had a short interpregnancy (IP) interval. The mean age at diagnosis of uterine rupture was 26.3 ± 5.1 weeks. The ruptures were associated with abnormal placentation in 10 cases (83.3%): placenta previa (n = 7); and placenta previa and percreta (n = 3). No maternal mortality occurred. Seven of the 10 (70%) viable newborns survived., Conclusions: The increasing rates of cesarean births (CB) may lead to iatrogenic complications including midgestational prelabor spontaneous uterine rupture, an obstetric emergency, which is hard to diagnose. Maternal and neonatal outcomes can be optimized by a greater awareness of the risk factors, recognition of clinical signs and symptoms, and the availability of ultrasound to assist in establishing a diagnosis to enable prompt surgical intervention., (© 2020 Wiley Periodicals LLC.)

Published
2021
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23. [SINGLE UTERINE PUNCTURE THROUGH THE INTERTWIN MEMBRANE IN TWIN PREGNANCY AMNIOCENTESIS: A DESCRIPTIVE STUDY OF OUR 9 YEARS' EXPERIENCE AT "SHAMIR" ("ASSAF HAROFEH") MEDICAL CENTER].

Author

Segall H, Shirazian-Bracha S, Melcer Y, Kugler N, and Maymon R

Subjects
Female, Humans, Pregnancy, Pregnancy Trimester, Second, Punctures, Retrospective Studies, Twins, Amniocentesis, Pregnancy, Twin
Abstract

Introduction: Obstetrics Gynecology Department, "Shamir" ("Assaf Harofeh") Medical Center, Tzrifin There are 2 methods to perform amniocentesis in twin pregnancy. The widespread method is the two-punctures technique (1 for each sac). The other is a single uterine puncture through the intertwin membrane. No method is known to be superior. The main procedure-related complications are increased risk for fetal loss, amniotic fluid leakage and infection. The information regarding complications in twin pregnancy is limited and the method is not described., Objectives: To demonstrate whether a single uterine puncture is an acceptable alternative to the double uterine puncture method., Methods: A retrospective cohort study of 112 twin pregnancies which underwent amniocentesis by a single operator at "Shamir" ("Assaf Harofeh") Medical Center between the years 2010-2018. We compared a single uterine puncture (intervention group) to a double uterine puncture (control group)., Results: Eighty-six patients (76.7%) underwent a single uterine puncture and 26 (23.3%) underwent a double uterine puncture. Most pregnancies were uncomplicated in both groups (80.2% vs. 76.9% respectively); no statistical difference was seen in any complication. The most common complication was seeking medical help due to bleeding or contraction (12.8% in single puncture group vs 19.2% in double puncture group). PPROM, infection and loss of pregnancy were rare., Conclusions: Only a few studies have related to the method of amniocentesis and compared the results of these 2 methods. A single uterine puncture does not bear an increased risk of complications compared to the double puncture.

Published
2020

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