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15 results on '"Kumar, Arunima"'

3. Edison Denies LA Wildfire Involvement as Insurers Ask It to Preserve Evidence.

Author

Dey, Bipasha and Kumar, Arunima

Subjects
STOCKS (Finance), MARKET capitalization, ELECTRIC lines, ELECTRONIC publications, INSURANCE costs, HOMEOWNERS insurance
Abstract

Southern California Edison has been asked by insurance companies to preserve evidence related to the Eaton Fire in Los Angeles, although no fire agencies have implicated the utility in the fire's ignition. Edison's shares declined following speculation that its equipment may have been involved in the fire. The wildfires in Los Angeles have caused significant damage and economic loss, with estimates reaching up to $150 billion, leading to concerns about recovery and insurance costs. [Extracted from the article]

Published
2025

4. News Discourse of Terror Attacks on Twitter: Comparative Analysis of CNN and Al Jazeera's Coverage of 2015 Islamic State Attacks in Beirut and Paris

Author

Kumar, Arunima, Jaggi, Ruchi, Kumar, Arunima, and Jaggi, Ruchi

Abstract

The period between 2014 and 2016 saw the rise of the radical Islamist terrorist group Islamic State (IS), which committed acts of terrorism in not only Syria and Iraq but also unleashed violence in the rest of the world. Twitter took the lead in being the source of receiving and giving quick updates on terror news. However, a key question that arises is about balanced coverage. Media made enormous efforts to humanize the terror attacks in the West, while what was happening in West Asia (Middle East) was constructed from a partisan political position. The researchers studied the coverage of the Beirut attack and the Paris attack, both of which took place in November 2015. The Twitter handles of Al Jazeera and CNN’s Breaking News were used to conduct the study. The data analysis establishes that there was a clear imbalance while covering Islamic State attacks in Paris and Beirut, respectively. The Paris attack received far more coverage from both CNN and Al Jazeera in terms of quantum and nature of issues addressed.

Published
2021

7. Oil Rises As Syria's Assad Departs, China Eases.

Author

Kumar, Arunima

Subjects
PRICES, MONEY supply, REAL estate sales, ECONOMIC stimulus, RISK premiums
Abstract

Oil prices increased by nearly 2% following the departure of Syrian President Bashar al-Assad and China's indication of a looser monetary policy. The rise in prices was attributed to heightened geopolitical risks and potential disruptions in the oil market due to the regime change in Syria. China's decision to boost domestic demand and consumption through unconventional adjustments may lead to a commodity price boom, impacting global oil markets. [Extracted from the article]

Published
2024

11. Comparative Evaluation of the Immune Responses and Protection Engendered by LC16m8 and Dryvax Smallpox Vaccines in a Mouse Model

Author

Meseda, Clement A., primary, Mayer, Anne E., additional, Kumar, Arunima, additional, Garcia, Alonzo D., additional, Campbell, Joseph, additional, Listrani, Paul, additional, Manischewitz, Jody, additional, King, Lisa R., additional, Golding, Hana, additional, Merchlinsky, Michael, additional, and Weir, Jerry P., additional

Published
2009
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14. A monoclonal antibody-based immunoassay for measuring the potency of 2009 pandemic influenza H1 N1 vaccines.

Author

Schmeisser, Falko, Vasudevan, Anupama, Soto, Jackeline, Kumar, Arunima, Williams, Ollie, and Weir, Jerry P.

Subjects
MONOCLONAL antibodies, IMMUNOASSAY, INFLUENZA A virus, H1N1 subtype, ANTIGENS, FEASIBILITY studies, VACCINATION
Abstract

Background The potency of inactivated influenza vaccines is determined using a single radial immunodiffusion ( SRID) assay. This assay is relatively easy to standardize, it is not technically demanding, and it is capable of measuring the potency of several vaccine strain subtypes in a multivalent vaccine. Nevertheless, alternative methods that retain the major advantages of the SRID, but with a greater dynamic range of measurement and with reduced reagent requirements, are needed. Objectives The feasibility of an ELISA-based assay format was explored as an alternative potency assay for inactivated influenza vaccines. Methods Several murine monoclonal antibodies (mAbs), specific for the 2009 pandemic H1 N1 influenza virus hemagglutinin ( HA), were evaluated for their potential to capture and quantify HA antigen. Vaccine samples, obtained from four licensed influenza vaccine manufacturers, included monovalent bulk vaccine, monovalent vaccine, and trivalent vaccine. Traditional SRID potency assays were run in parallel with the mAb- ELISA potency assay using the reference antigen standard appropriate for the vaccine samples being tested. Results The results indicated that the ELISA potency assay can quantify HA over a wide range of concentrations, including vaccine at subpotent doses, and the ELISA and SRID potency values correlated well for most vaccine samples. Importantly, the assay was capable of quantifying A/California HA in a trivalent formulation. Conclusions This study demonstrates the general feasibility of the mAb approach and strongly suggests that such ELISAs have potential for continued development as an alternative method to assay the potency of inactivated influenza vaccines. [ABSTRACT FROM AUTHOR]

Published
2014
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15. Characterization and Use of Mammalian-Expressed Vaccinia Virus Extracellular Membrane Proteins for Quantification of the Humoral Immune Response to Smallpox Vaccines

Author

Garci´a, Alonzo D., Meseda, Clement A., Mayer, Anne E., Kumar, Arunima, Merchlinsky, Michael, and Weir, Jerry P.

Abstract

ABSTRACTThe licensed smallpox vaccine Dryvax is used as the standard in comparative immunogenicity and protection studies of new smallpox vaccine candidates. Although the correlates of protection against smallpox are unknown, recent studies have shown that a humoral response against the intracellular mature virion and extracellular enveloped virion (EV) forms of vaccinia virus is crucial for protection. Using a recombinant Semliki Forest virus (rSFV) vector system, we expressed a set of full-length EV proteins for the development of EV antigen-specific enzyme-linked immunosorbent assays (ELISAs) and the production of monospecific antisera. The EV-specific ELISAs were used to evaluate the EV humoral response elicited by Dryvax and the nonreplicating modified vaccinia virus Ankara (MVA) in mouse vaccination experiments comparing doses and routes of vaccination. Quantitatively similar titers of antibodies against EV antigens A33R, A56R, and B5R were measured in mice vaccinated with Dryvax and MVA when MVA was administered at a dose of 108plaque-forming units. Further, a substantial increase in the EV-specific antibody response was induced in mice inoculated with MVA by using a prime-boost schedule. Finally, we investigated the abilities of the EV-expressing rSFV vectors to elicit the production of polyclonal monospecific antisera against the corresponding EV proteins in mice. The monospecific serum antibody levels against A33R, A56R, and B5R were measurably higher than the antibody levels induced by Dryvax. The resulting polyclonal antisera were used in Western blot analysis and immunofluorescence assays, indicating that rSFV particles are useful vectors for generating monospecific antisera.

Published
2007
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