24 results on '"Kuno, Haruhiko"'
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2. Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement
3. TAK-137, an AMPA-R potentiator with little agonistic effect, has a wide therapeutic window
4. Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective α1D adrenoceptor antagonists
5. Design, synthesis, and biological activity of novel, potent, and highly selective fused pyrimidine-2-carboxamide-4-one-based matrix metalloproteinase (MMP)-13 zinc-binding inhibitors
6. Structure determination, synthesis, and biological evaluation of a metabolite of the selective α1D adrenoceptor antagonist TAK-259
7. Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: Highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site
8. TAK-137, an AMPA-R potentiator with little agonistic effect, has a wide therapeutic window
9. A simple and rapid reverse transcriptase assay for the detection of retroviruses in cell cultures
10. Establishment of an epidermal growth factor-dependent, multipotent neural precursor cell line
11. Identification of a novel series of potent and selective CCR6 inhibitors as biological probes
12. Development of a flowchart for extracting places with high risk slope of failure in an earthquake around transmission towers
13. Platelet-like particle formation in the human megakaryoblastic leukaemia cell lines, MEG-01 and MEG-01s
14. HBT1, a Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Avoided Bell-Shaped Response in In Vitro BDNF Production
15. Identification of 3,4-dihydro-2 H -thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective α 1D adrenoceptor antagonists
16. Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach
17. Discovery of 5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carboxamide (TAK-259) as a Novel, Selective, and Orally Active α1D Adrenoceptor Antagonist with Antiurinary Frequency Effects: Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities
18. Discovery of Novel, Highly Potent, and Selective Quinazoline-2-carboxamide-Based Matrix Metalloproteinase (MMP)-13 Inhibitors without a Zinc Binding Group Using a Structure-Based Design Approach
19. An investigation on rainfall infiltration phenomenon in unconsolidated ground
20. THE ANALYZING METHOD OF GROUND BEHAVIOR BY THE PRINCIPAL COMPONENT ANALYSIS
21. Development of ultra-fast data acquisition system for electrical resistivity surveys
22. Slope maintenance system using GIS, and application to slope around the existing structure.
23. Discovery of Novel, HighlyPotent, and Selective Quinazoline-2-carboxamide-BasedMatrix Metalloproteinase (MMP)-13 Inhibitors without a Zinc BindingGroup Using a Structure-Based Design Approach.
24. Cytokines affecting survival and differentiation of an astrocyte progenitor cell line
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