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We report a girl who was diagnosed with choroid plexus carcinoma at the age of 7 and has had an active daily life in the 11 years after onset. She underwent two tumor excision operations and received radiotherapy followed by intensive chemotherapy using cisplatin, carboplatin, and etoposide. In general, the prognosis of choroid plexus carcinoma is very poor, especially in the childhood cases, since no optimal treatment for choroid plexus carcinoma has yet been established. However, the results of analyses of the present long-term survival case, and similar long-term survival cases in the literature, strongly suggest the usefulness of chemotherapy in the treatment of choroid plexus carcinoma in children.

In order to examine the relationship between the hemostatic systems and the severity of neurological changes, shortly after spontaneous subarachnoid hemorrhage (SAH) we reviewed 30 patients who had been admitted within 6 hours after the onset of SAH. Peripheral blood samples were obtained within 6 hours of the onset of SAH. There was a significant correlation between increased values of serum antithrombin III, thrombin-antithrombin III complexes, fibrinopeptide B beta 15-42, D-dimers, and the neurological severity of SAH. The data suggest that the activation of the blood coagulation system as well as the fibrinolytic system (especially the secondary fibrinolysis) occurs early in the course of SAH, particularly in patients with a severe neurological condition.