27 results on '"Kwaasi, Aaron"'
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2. The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants
3. The relationship between the chemistry and biological activity of the bisphosphonates
4. Hsp-72, a candidate prognostic indicator of heatstroke
5. Bisphosphonates: An Update on Mechanisms of Action and How These Relate to Clinical Efficacy
6. The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-α]Pyridin-3-yl)-Ethyl-Bisphosphonate)
7. The pharmacological profile of a novel highly potent bisphosphonate, OX14 (1-fluoro-2-(imidazo-[1,2 alpha]pyridin-3-yl)ethyl-bisphosphonate), with reduced bone affinity, which is as effective as zoledronate in the treatment of myeloma bone disease in JJN3-NOD/SCID-[gamma] mice
8. Differential effects of nitrogen-containing bisphosphonates on human PBMCs and MUTZ-3 cells
9. Designed mutants of human farnesyl pyrophosphate synthase (FPPS) help to characterise the interactions of nitrogen-containing bisphosphonates with Tyrosine 204 and Phenylalanine 239 side-chain residues
10. BISPHOSPHONATES AFFECT HUMAN OSTEOCLAST DEVELOPMENT IN VITRO
11. Design, Synthesis, and Biological Evaluation of Novel Aminobisphosphonates Possessing an in Vivo Antitumor Activity Through a γδ-T Lymphocytes-Mediated Activation Mechanism
12. Recombinant Activated Protein C Attenuates Endothelial Injury and Inhibits Procoagulant Microparticles Release in Baboon Heatstroke
13. Apolipoprotein A-l/C-lll gene cluster polymorphism in Saudi Arabians, Filipinos and Caucasians
14. Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase
15. Structure activity relationships of nitrogen containing bisphosphonates which induce conformational changes in farnesyl pyrophosphate synthase
16. The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates
17. Bisphosphonates
18. GLUCOCORTICOIDS DO NOT PROTECT AGAINST THE LETHAL EFFECTS OF EXPERIMENTAL HEATSTROKE IN BABOONS
19. CIRCULATING HSP-72 IS AN EARLY AND LONG LASTING MARKER OF HEATSTROKE SEVERITY.
20. DEXAMETHASONE DOES NOT PROTECT AGAINST THE LETHAL EFFECTS OF INDUCED HEATSTROKE IN BABOONS.
21. RAGE-mediated neutrophil dysfunction is evoked by advanced glycation end products (AGEs)
22. ALPHA-GAL-INDEPENDENT DUAL RECOGNITION AND ACTIVATION OF XENOGENEIC ENDOTHELIAL CELLS AND HUMAN NA??VE NATURAL KILLER CELLS1
23. Coronary artery disease and apolipoprotein A‐I/C‐III gene polymorphism: a study of Saudi Arabians
24. ALPHA-GAL-INDEPENDENT DUAL RECOGNITION AND ACTIVATION OF XENOGENEIC ENDOTHELIAL CELLS AND HUMAN NAÏVE NATURAL KILLER CELLS1.
25. Apolipoprotein A-l/C-lll gene cluster polymorphism in Saudi Arabians, Filipinos and Caucasians.
26. 425 In-vitro regulation of immune cell functions by human IgE
27. Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.
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