545 results on '"Kwekkeboom, Jaap"'
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2. Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells
3. GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells
4. Minimal Development of Liver Fibrosis in Adult Tolerant Liver Transplant Recipients Late After Immunosuppressive Drug Weaning and Transplantation
5. Immune suppressive checkpoint interactions in the tumour microenvironment of primary liver cancers
6. Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance
7. Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules
8. Enrichment of the tumour immune microenvironment in patients with desmoplastic colorectal liver metastasis
9. HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis
10. LGR5 marks targetable tumor-initiating cells in mouse liver cancer
11. Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma
12. JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa
13. Immunosuppressive drug withdrawal late after liver transplantation improves the lipid profile and reduces infections
14. 883 MCLA-145, an anti CD137×PD-L1 bispecific antibody, induces T cell activation and proliferation in ex vivo models of hepatocellular carcinoma
15. 1181 Therapeutic vaccines consisting of cancer germline antigen-based synthetic long peptides are immunogenic in human hepatocellular carcinoma patients
16. Donor‐specific anti‐HLA antibodies are not associated with nonanastomotic biliary strictures but both are independent risk factors for graft loss after liver transplantation
17. Suppression of Hepatocellular Carcinoma by Mycophenolic Acid in Experimental Models and in Patients
18. Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra-tumoral expression levels
19. Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients
20. Kupffer Cells Interact With Hepatitis B Surface Antigen In Vivo and In Vitro, Leading to Proinflammatory Cytokine Production and Natural Killer Cell Function
21. Modulation of Dendritic Cells and Regulatory T Cells by Naturally Occurring Antibodies
22. Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells
23. Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells
24. Differential Sensitivities of Fast- and Slow-Cycling Cancer Cells to Inosine Monophosphate Dehydrogenase 2 Inhibition by Mycophenolic Acid
25. Current Tolerance-Associated Peripheral Blood Gene Expression Profiles After Liver Transplantation Are Influenced by Immunosuppressive Drugs and Prior Cytomegalovirus Infection
26. Immune suppressive checkpoint interactions in the tumour microenvironment of primary liver cancers
27. An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity
28. Polarized release of hepatic microRNAs into bile and serum in response to cellular injury and impaired liver function
29. Pretreatment Intrahepatic $CD8^(+)$ Cell Count Correlates with Virological Response to Antiviral Therapy in Chronic Hepatitis C Virus Infection
30. TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer
31. Activated CD4 + T Cells and Highly Differentiated Alloreactive CD4 + T Cells Distinguish Operationally Tolerant Liver Transplantation Recipients
32. Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma
33. Expression of Cancer Testis Antigens in Tumor-Adjacent Normal Liver Is Associated with Post-Resection Recurrence of Hepatocellular Carcinoma
34. HLA matching and rabbit antithymocyte globulin as induction therapy to avoid multiple forms of rejection after a third liver transplantation
35. Targeting Gitr Enhances Human Tumour-infiltrating T Cell Functionality in Mismatch Repair Proficient Primary Colorectal Carcinoma and Liver Metastases
36. Cancer Cell B7-H3 Expression Is More Prevalent in the Pancreato-Biliary Subtype of Ampullary Cancer Than in Pancreatic Cancer
37. Modulation of the cellular immune system by intravenous immunoglobulin
38. Prevention of immunoglobulin G immobilization eliminates artifactual stimulation of dendritic cell maturation by intravenous immunoglobulin in vitro
39. T-cell inhibitory capacity of hyperimmunoglobulins is influenced by the production process
40. Combined antiviral activity of interferon-α and RNA interference directed against hepatitis C without affecting vector delivery and gene silencing
41. Cancer inflammation and inflammatory biomarkers: can neutrophil, lymphocyte, and platelet counts represent the complexity of the immune system?
42. TIGIT and PD1 Co-blockade Restores ex vivo Functions of Human Tumor-Infiltrating CD8+ T Cells in Hepatocellular Carcinoma
43. Camrelizumab—targeting a novel PD-1 epitope to treat hepatocellular carcinoma
44. 588 Targeting GITR enhances human tumour-infiltrating T cell functionality in mismatch repair proficient primary colorectal carcinoma and liver metastases
45. Strain-specific in vitro cytokine production profiles do not predict rat liver allograft survival
46. The biological process of lysine‐tRNA charging is therapeutically targetable in liver cancer
47. FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells
48. Modelling liver tumor organoids and cancer-associated fibroblasts interaction reveals the robust effects of stromal niche in cancer nurturing and treatment resistance
49. Identification of a panel of safe immunogenic antigens for therapeutic vaccination strategies in hepatocellular carcinoma
50. TIGIT and PD1 dual checkpoint blockade restores functionality of tumor-infiltrating T cells in hepatocellular carcinoma
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