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30 results on '"Kwon, Seong Soon"'

7. Neutrophil‐to‐lymphocyte ratio and platelet‐to‐lymphocyte ratio as new possible minor criteria for diagnosis of polycythemia vera.

Author

Kim, Min Jung, Kwon, Seong Soon, Ji, Young Sok, Lee, Min‐Young, Kim, Kyoung Ha, Lee, Namsu, Park, Sung Kyu, Won, Jong‐Ho, and Yoon, Seug Yun

Subjects
*BIOMARKERS, *PLATELET lymphocyte ratio, *POLYCYTHEMIA vera, *GENETIC mutation, *POLYCYTHEMIA, *RETROSPECTIVE studies, *ACQUISITION of data, *NEUTROPHIL lymphocyte ratio, *COMPARATIVE studies, *JANUS kinases, *MEDICAL records, *DESCRIPTIVE statistics, *RESEARCH funding, *RECEIVER operating characteristic curves, *SENSITIVITY & specificity (Statistics), *ERYTHROPOIETIN, *EVALUATION
Abstract

Introduction: The role of inflammation in the pathophysiology of polycythemia vera (PV) is important. The presence of JAK2 mutations is important in the diagnosis of PV, and serum levels of erythropoietin (EPO) also play a supporting role. However, serum EPO levels show some limitations. The neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) are a readily available marker of inflammation. Thus, we examined whether NLR & PLR might diagnose PV in erythrocytosis patients. We compared NLR & PLR and EPO diagnostic values. Methods: We retrospectively reviewed clinical and laboratory data from two referral hospitals. Two hundred and eighty‐five patients with erythrocytosis who underwent a test for the JAK2 mutation were included. It wac classified as the PV group and the secondary polycythemia (SP) group. Results: The median NLR & PLR in the PV group (n = 70) was significantly higher than that in the SP group (n = 170) (NLR: 6.04 vs. 1.77, PLR: 283.18 vs. 101.56, respectively, p < 0.001). In the receiver operating characteristic analysis, the area under the curve of NLR & PLR was significantly higher than that of serum EPO (NLR vs EPO: 0.921 vs. 0.827, p = 0.003; PLR vs EPO: 0.917 vs 0.827, p = 0.003). Conclusion: In conclusion, NLR & PLR were higher in PV than in SP and showed better diagnostic value than serum EPO level, highlighting their potential as minor diagnostic criteria in patients with PV. [ABSTRACT FROM AUTHOR]

Published
2023
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8. Temporal Trend of the Incidence and Characteristics of Renal Infarction: Korean Nationwide Population Study

Author

Kim, Dong-Eon, primary, Moon, Inki, additional, Park, Suyeong, additional, Park, Minae, additional, Park, Sojeong, additional, Kwon, Seong Soon, additional, Kong, Min Gyu, additional, Park, Hyun Woo, additional, Choi, Hyung Oh, additional, Seo, Hye-Sun, additional, Cho, Yoon Haeng, additional, Lee, Nae Hee, additional, and Suh, Jon, additional

Published
2023
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26. Consideration of Discrepancy between Needle-Washout Thyroglobulin and Serum Thyroglobulin of Recurrent Papillary Thyroid Cancer

Author

Kim, So Ra, primary, Kwak, Mi-Kyung, additional, Kang, Hye Ran, additional, Yoon, Seug Yun, additional, Kwon, Seong Soon, additional, Kim, Bo Young, additional, Choi, Hoo Nam, additional, Kim, Hye Jeong, additional, Kim, Jae Wook, additional, Jin, So-Young, additional, Park, Hyeong Kyu, additional, Byun, Dong Won, additional, Suh, Kyoil, additional, and Yoo, Myung-Hi, additional

Published
2014
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30. Association of Higher Hemoglobin Level With Significant Carotid Artery Plaque in the General Population.

Author

Kwon SS, Yoon SY, Kim KH, Park BW, Lee MH, Kim H, and Bang DW

Abstract

Objective: Serum hemoglobin (Hb) level affects the viscosity of blood. Several studies have reported that Hb level is associated with adverse cardiovascular outcome. However, there is a paucity of evidence on the association between serum Hb level and the risk of subclinical atherosclerosis. Thus, the objective of this study was to investigate the relationship between Hb level and risk of carotid plaque in a health checkup cohort., Methods: This retrospective study analyzed a total of 3,805 individuals without history of cardiovascular disease (CVD) who underwent carotid ultrasonography (USG) between January 2016 and June 2018. Participants were divided into 4 groups based on Hb quartiles in each of male and female. Carotid plaque score was calculated based on USG reports. Multivariable logistic regression analysis was performed for each index of quartile groups regarding the risk of carotid plaque., Results: Of 3,805 individuals (mean age, 52.62±10.25 years; 2,674 [70.28%] males), mean Hb level was 15.11±0.75 g/dL in male and 13.35±0.74 g/dL in female. When the Q1 group was compared to the Q4, increasing quartile of Hb was associated with the presence of significant carotid plaque (plaque score ≥3) in male (adjusted odds ratio [OR], 1.538; 95% confidence interval [CI], 1.182-2.001; p =0.001) and female (adjusted OR, 1.749; 95% CI, 1.058-2.676; p =0.01)., Conclusion: A high Hb level is associated with an increased risk of carotid plaques in individuals without history of CVD. This finding may support the need for early screening of CVD in individuals with high Hb levels., Competing Interests: Conflict of Interest: The authors have no conflicts of interest to declare., (© 2024 The Korean Society of Lipid and Atherosclerosis.)

Published
2024
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