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Hypohydration can impair aerobic performance and deteriorate cognitive function during exercise. To minimize hypohydration, athletes are recommended to commence exercise at least euhydrated, ingest fluids containing sodium during long-duration and/or high-intensity exercise to prevent body mass loss over 2% and maintain elevated plasma osmolality, and rapidly restore and retain fluid and electrolyte homeostasis before a second exercise session. To achieve these goals, the compositions of the fluids consumed are key; however, it remains unclear what can be considered an optimal formulation for a hydration beverage in different settings. While carbohydrate-electrolyte solutions such as sports drinks have been extensively explored as a source of carbohydrates to meet fuel demands during intense and long-duration exercise, these formulas might not be ideal in situations where fluid and electrolyte balance is impaired, such as practicing exercise in the heat. Alternately, hypotonic compositions consisting of moderate to high levels of electrolytes (i.e., ≥45 mmol/L), mainly sodium, combined with low amounts of carbohydrates (i.e., <6%) might be useful to accelerate intestinal water absorption, maintain plasma volume and osmolality during exercise, and improve fluid retention during recovery. Future studies should compare hypotonic formulas and sports drinks in different exercise settings, evaluating different levels of sodium and/or other electrolytes, blends of carbohydrates, and novel ingredients for addressing hydration and rehydration before, during, and after exercise.

High-level football (soccer) players face intense physical demands that result in acute and residual fatigue, impairing their physical performance in subsequent matches. Further, top-class players are frequently exposed to match-congested periods where sufficient recovery times are not achievable. To evaluate training and recovery strategies, the monitoring of players' recovery profiles is crucial. Along with performance and neuro-mechanical impairments, match-induced fatigue causes metabolic disturbances denoted by changes in chemical analytes that can be quantified in different body fluids such as blood, saliva, and urine, thus acting as biomarkers. The monitoring of these molecules might supplement performance, neuromuscular and cognitive measurements to guide coaches and trainers during the recovery period. The present narrative review aims to comprehensively review the scientific literature on biomarkers of post-match recovery in semi-professional and professional football players as well as provide an outlook on the role that metabolomic studies might play in this field of research. Overall, no single gold-standard biomarker of match-induced fatigue exists, and a range of metabolites are available to assess different aspects of post-match recovery. The use of biomarker panels might be suitable to simultaneously monitoring these broad physiological processes, yet further research on fluctuations of different analytes throughout post-match recovery is warranted. Although important efforts have been made to address the high interindividual heterogeneity of available markers, limitations inherent to these markers might compromise the information they provide to guide recovery protocols. Further research on metabolomics might benefit from evaluating the long-term recovery period from a high-level football match to shed light upon new biomarkers of post-match recovery., Competing Interests: ÍP-C, RR, and HB were employed by Abbott Laboratories. JL-C and NM were employed by Real Madrid., (Copyright © 2023 Pérez-Castillo, Rueda, Bouzamondo, López-Chicharro and Mihic.)

The incidence and risk factors for poor outcome in patients with COVID are well known, as are the protective measures in high-risk populations. In contrast, the epidemiological and clinical behavior of this disease in the population of elite athletes who are the paradigm of good health is poorly understood. Data on COVID in athletes are scarce and have focused preferentially on the consequences on sports performance of confinement measures and on the pathophysiological risks of infected athletes. Real Madrid is a large elite sports institution with facilities in the City of Madrid where 600 athletes train daily. The incidence of COVID during a study period of 671 days of observation in athletes, professional or amateur, working in the institution has been 0,74 per 1,000 days of exposure. The disease has been asymptomatic or oligosymptomatic in all athletes and did not require any hospital admissions. The different teams did not have to suspend any of its sportive commitments for COVID during the study period and there was no evidence of outbreaks of internal transmission between members of the different teams., (©The Author 2022. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).)

Purpose : The aim of this study was to determine the changes in neuromuscular contractile properties in elite cyclists associated to the peripheral fatigue produced in a maximal incremental test in cycle ergometer. Methods : Forty-eight volunteers' well-trained male cyclists were evaluated during the competition season within a recovery microcycle. Tensiomyography was used before and after performing an incremental test until exhaustion in cycle ergometer to measure the radial muscle belly displacement of the vastus lateralis (VL), rectus femoris (RF), and biceps femoris (BF) on the dominant leg. Maximum radial muscle belly displacement (Dm), contraction time (Tc), delay time (Td), sustain time (Ts), and radial displacement velocity (Vrd) were measured. Mixed-design factorial analysis of variance was used to detect changes in the mechanical and neuromuscular characteristics after a maximal incremental exercise test. Results : The results show in the evaluated muscles a moderate-large decrease ( p < .01, η2 = 0.06-0.51) in Tc, Td, Dm, Ts, and Vrd. This decrease occurs more sharply in the BF than in RF or VL. Conclusion : An incremental effort until exhaustion produces peripheral fatigue associated with a decrease in Dm, Tc, Td, Ts, and Vrd, being more pronounced in biceps femoris than in vastus lateralis and rectus femoris. Coaches can use these changes found in the contractile properties as a reference to detect the muscle fatigue degree that certain training models pose for the cyclist.

Background: Mechanical efficiency (ME) refers to the ability of an individual to transfer energy consumed by external work. A decreased ME, could represent an increased energy cost during exercise and may, therefore, be limited in terms of physical activity. This study aimed to compare the influence of two different exercise protocols: moderate continuous training (MCT) versus high intensity interval training (HIIT), as part of a cardiac rehabilitation program on ME values among coronary patients., Methods: One hundred and ten coronary patients were assigned to either HIIT or MCT groups for 8 weeks. Incremental exercise tests in a cycle ergometer were performed to obtain VO2peak. Net energy expenditure (EE) and ME were obtained at intensities corresponding to the first (VT1) and second (VT2) ventilatory thresholds, and at VO2peak., Results: Both exercise programs significantly increase VO2peak with a higher increase in the HIIT group (2.96 ± 2.33 mL/kg/min vs. 3.88 ± 2.40 mL/kg/min, for patients of the MCT and HIIT groups, respectively, p < 0.001). The ME at VO2peak and VT2 only significantly increased in the HIIT group. At VT1, ME significantly increased in both groups, with a greater increase in the HIIT group (2.20 ± ± 6.25% vs. 5.52 ± 5.53%, for patients of the MCT and HIIT groups, respectively, p < 0.001)., Conclusions: The application of HIIT to patients with chronic ischemic heart disease of low risk re- sulted in a greater improvement in VO2peak and in ME at VT1, than when MCT was applied. Moreover, only the application of HIIT brought about a significant increase in ME at VT2 and at VO2peak.

The aim was to determine the predictive capacity of neuromuscular parameters on physiological predictors of performance related to pedaling power. The sample comprised fifty elite cyclists. On the same day, they were given a neuromuscular evaluation with tensiomyography (TMG) and then performed an effort test on a cycle ergometer until exhaustion. The TMG recorded the maximum radial muscle belly displacement, contraction time, delay time, derivative normalized response speed, and lateral symmetry. Peak power output (Wpeak·kg -1 ), effort time, maximum lactate concentration, power in the first lactate threshold, and power in the second lactate threshold were recorded in the effort test. Linear regression analysis was used to determine the explanatory capacity of neuromuscular parameters on potential cycling performance indicators. A higher Wpeak·kg -1 during a maximal incremental test on the cycle ergometer can be predicted moderately (R 2 =0.683; R 2 a=0.615; R=0.826; Std. Error=0.26017; p<0.001) by a longer rectus femoris contraction time and a greater radial muscle belly displacement of the vastus lateralis and vastus medialis as well as a slower normalized response speed of the biceps femoris. In conclusion, neuromuscular parameters can partially explain performance in a specific cycling test until exhaustion., Competing Interests: The authors declare no conflict of interest., (© Georg Thieme Verlag KG Stuttgart · New York.)

Background: Indoor cycling sessions are usually guided by heart rate (HR) and rating of perceived exertion (RPE). This study was designed to examine the effects of sex, age, previous experience, use of a HR monitor, estimated sweat rate and room temperature and humidity increases on HR and RPE during indoor cycling sessions., Methods: Measurements were made in 39 sessions performed by 300 experienced subjects. Sweat rate was categorized as SR1≥750 mL, SR2 400-749 mL, and SR3<400 mL; temperature increase as T1≤0.2 °C, T2 0.2-1.5 °C, and T3>1.5 °C; and humidity as H1≤2%, H2 2-15%, and H3>15%. Mean HR was determined for the sessions and RPE recorded at the start, middle and end of each session., Results: Significant differences in HR were observed between SR1 and SR3 (148.22±12.17 vs. 141.73±17.39 bpm; P<0.05) and between T1 and T2 (141.01±16.38 vs. 146.95±15.29 bpm; P<0.05). The RPE was lower (P<0.05) for T1 than T2 or T3 in all recordings and for H1 than H2 or H3 at the session start and middle., Conclusions: Our results indicate that real (%HRmax) and perceived (RPE) intensity of exercise in an indoor cycling session are influenced by factors such as the estimated sweat rate, or the increase in temperature or relative humidity produced in the cycling room.

Background: Self-measurement of blood pressure is a priority strategy for managing blood pressure., Objective: The aim of this study was to evaluate the reliability and validity of blood pressure and heart rate following the European Society of Hypertension's international validation protocol, as measured with the QardioArm, a fully automatic, noninvasive wireless blood pressure monitor and mobile app., Methods: A total of 100 healthy volunteers older than 25 years from the general population of Ciudad Real, Spain, participated in a test-retest validation study with two measurement sessions separated by 5 to 7 days. In each measurement session, seven systolic blood pressure, diastolic blood pressure, and heart rate assessments were taken, alternating between the two devices. The test device was the QardioArm and the previously validated criterion device was the Omron M3. Sessions took place at a single study site with an evaluation room that was maintained at an appropriate temperature and kept free from noises and distractions., Results: The QardioArm displayed very consistent readings both within and across sessions (intraclass correlation coefficients=0.80-0.95, standard errors of measurement=2.5-5.4). The QardioArm measurements corresponded closely to those from the criterion device (r>.96) and mean values for the two devices were nearly identical. The QardioArm easily passed all validation standards set by the European Society of Hypertension International Protocol., Conclusions: The QardioArm mobile app has validity and it can be used free of major measurement error., (©Victoria Mazoteras Pardo, Marta E Losa Iglesias, José López Chicharro, Ricardo Becerro de Bengoa Vallejo. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 15.12.2017.)

Background: Despite a growing clinical interest in determining the heart rate recovery (HRR) response to exercise, the limits of a normal HRR have not yet been well established., Purpose: This study was designed to examine HRR following a controlled maximal exercise test in healthy, physically active adult men., Methods: The subjects recruited (n = 789) performed a maximal stress test on a treadmill. HRR indices were calculated by subtracting the first and third minute heart rates (HRs) during recovery from the maximal HR obtained during stress testing and designated these as HRR-1 and HRR-3, respectively. The relative change in HRR was determined as the decrease in HR produced at the time points 1 and 3 min after exercise as a percentage of the peak HR (%HRR-1/HR(peak) and %HRR-3/HR(peak), respectively). Percentile values of HRR-1 and HRR-3 were generated for the study population., Results: Mean HHR-1 and HHR-3 were 15.24 ± 8.36 and 64.58 ± 12.17 bpm, respectively, and %HRR-1/HR(peak) and %HRR-3/HR(peak) were 8.60 ± 4.70 and 36.35 ± 6.79%, respectively. Significant correlation was detected between Peak VO2 and HRR-3 (r = 0.36; p < 0.001) or %HRR-3/HR(peak) (r = 0.23; p < 0.001)., Conclusions: Our study provides normality data for HRR following a maximal Ergometry test obtained in a large population of physically active men.

The aim of this study was to analyze surface electromyography activity (sEMG) and rating of perceived exertion (RPE) responses in different muscles while standing on a vibrating platform producing oscillations of different frequencies and amplitudes. Twenty community-dwelling older adults (79.6 ± 3.2 years) took part in the research. Subjects were exposed to 12 different vibration treatments of 15 seconds separated by 1 minute of rest in random order to check the influence of frequency (25, 35, and 45 Hz) and amplitude (1 mm [low] and 3.1 mm [high]) vibration on sEMG signal and RPE. Additionally, the use of a soft pad was also examined for its influence on these measures. Three-factor analysis of variance for RPE and both lower and whole-body sEMGs revealed a significant amplitude main effect (p < 0.01), and soft mat effect (p < 0.01), and a significant frequency main effect (p < 0.01). The major findings were that sEMG and RPE increased with the acceleration of the vibration; moreover, the increments of sEMG were highly correlated with RPE. The results of this study suggest that using the RPE method after each exercise would allow exercise and health professionals to assess the intensity levels that correspond to the level of the vibratory program in older adults.

Maximal exercise performance in patients with chronic heart failure, as determined by peak oxygen consumption (VO2max.) during exercise testing has been shown to correlate well with mortality and its use as primary determining factor in the selection of patients for heart transplant has been advocated. Patients with a VO2max of less than 14 ml/kg/min appear at particularly high risk for mortality. Exercise performance can be influenced by a number of independent factors including subject motivation, peripheral deconditioning or other intrinsic abnormalities of skeletal muscle, and primary respiratory disease. It appears to be a precise gauge of functional impairment. VO2max can be used to accurately and reproducibly place an individual in a predefined functional class.