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217 results on '"Lösch U"'

3. Lack of Alloantigen-Specific Cytotoxic T Cell Activity in the TCR-γδT Cell Subpopulation of Alloantigen-Immune Chickens

Author

Cihak, J., Merkle, H., Lösch, U., Compans, R. W., editor, Cooper, M., editor, Koprowski, H., editor, McConnell, I., editor, Melchers, F., editor, Nussenzweig, V., editor, Oldstone, M., editor, Olsnes, S., editor, Potter, M., editor, Saedler, H., editor, Vogt, P. K., editor, Wagner, H., editor, Wilson, I., editor, Pfeffer, Klaus, editor, Heeg, Klaus, editor, Wagner, Hermann, editor, and Riethmüller, Gert, editor

Published
1991
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5. Nebenwirkungen von Adjuvantien bei den Spezies Maus und Huhn

Author

Erhard, M. H., Hofmann, A., Schmidt, P., Stangassinger, M., Lösch, U., Schöffl, Harald, editor, Spielmann, Horst, editor, Tritthart, Helmut A., editor, Cußler, Klaus, editor, Goetschel, Antoine F., editor, Gruber, Franz P., editor, and Reinhardt, Christoph A., editor

Published
1997
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11. Ontogeny of T Cells and a Third Lymphocyte Lineage in the Chicken

Author

Cooper, M. D., Sanchez, P., Char, D., George, J. F., Lahti, J. M., Bucy, R. P., Chen, C. H., Cihak, J., Lösch, U., Coltey, M., Le Douarin, N. M., Melchers, Fritz, editor, Albert, E. D., editor, von Boehmer, H., editor, Dierich, M. P., editor, Du Pasquier, L., editor, Eichmann, K., editor, Gemsa, D., editor, Götze, O., editor, Kalden, J. R., editor, Kaufmann, S. H. E., editor, Kirchner, H., editor, Resch, K., editor, Riethmüller, G., editor, Schimpl, A., editor, Sorg, C., editor, Steinmetz, M., editor, Wagner, H., editor, and Zachau, H. G., editor

Published
1989
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12. [Significance and course of a cold agglutinin in Eperythrozoon suis infection of swine]

Author

Jüngling A, Michael Helmut Erhard, Heinritzi K, and Lösch U

Subjects
Swine Diseases, Erythrocytes, Immunoglobulin M, Agglutinins, Swine, Erythrocyte Count, Animals, Mycoplasma Infections, Anemia, Hemolytic, Autoimmune, Cryoglobulins
Abstract

After infection with Eperythrozoon suis, pigs began to produce cold agglutinins of immunoglobulin type IgM, that because of the similarity between the pathogenic antigen and antigen on the erythrocyte membrane caused agglomeration. The progression of this cold agglutinin was measured with an enzyme immunoassay especially invented for this purpose, and compared with serum-IgM, agglutination strength, pathogenic effect as well as number of erythrocytes in the blood. The cold agglutinin extracted from the erythrocyte membrane at 40 degrees C showed, in comparison to the initial figures, a higher level (1259 micrograms/ml) at 6 days after the illness peak, reaching its maximum (2435 micrograms/ml) at 12 days. Similar results were achieved at lower extraction temperatures (22 degrees C, 0 degree C). A high correlation could be shown between the levels of IgM and of cold agglutinin, as well as the parallel increase in the agglutination strength of the blood. At the time of maximal pathogenic effect, no agglutination of blood was observed. The number of erythrocytes decreased in acute phases of an attack to a constant mean of 2.32 Mill./microliters of blood and then increased, at the same rate as the cold agglutinin level decreased, almost reaching normal values. These experiments confirm the fact that an organism following an infection with Eperythrozoon suis, begins to produce cold agglutinins. Due to structural similarities between the pathogen and the erythrocyte antigen the cold agglutinin causes temperature dependent agglutination.(ABSTRACT TRUNCATED AT 250 WORDS)

Published
1994

22. [New possibilities in oral immunoprophylaxis of newborn diarrhea in calves--a field study using specific egg antibodies]

Author

Michael Helmut Erhard, Kellner J, Eichelberger J, and Lösch U

Subjects
Diarrhea, Male, Rotavirus, Animals, Newborn, Eggs, Escherichia coli, Immunization, Passive, Animals, Cattle Diseases, Cattle, Female, Chickens
Abstract

To investigate the effect of oral immunoprophylaxis in diarrhea of newborn calves egg powder with antibodies specific to E. coli K99 (ETEC) and rotavirus were used in a field trial in south west Germany. Fourteen farms with a total of 105 calves were selected. Egg powder (21 g per day) was fed as a supplement to the regular diet for the first 14 days after birth. Animals of the control group received egg powder derived from hens not immunized with the antigens. Frequency, duration and severity of diarrhea, fecal dry matter and weight gain were examined in order to evaluate the influence of the specific egg powder. Using a Lactovac test kit pathogens were detected in the feces of 76.2% of the calves, with 24.7% infected with E. coli K99, 39.1% with rotavirus, 19.0% with coronavirus and 32.4% with cryptosporidia. An overall reduction in diarrhea frequency from 68.5% to 52.9% was observed in calves fed with specific antibodies. Animals with an E. coli K99 infection showed a reduction from 92.3% to 30.7% and those infected exclusively with E. coli K99 from 83.3% to 0%. The duration of diarrhea was significantly reduced (42 h) in animals fed with specific antibodies in comparison to the control animals (60 h). With the exception of animals infected with coronavirus a marked reduction in the severity of diarrhea was observed in antibody treated calves. During the first 14 days after birth antibody treated calves showed a weight gain of 5.6 kg on average in comparison with 3.5 kg in the control group.(ABSTRACT TRUNCATED AT 250 WORDS)

Published
1993

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