Search

Your search keyword '"Lüthy R"' showing total 517 results
Start Over Author "Lüthy R"
517 results on '"Lüthy R"'

1. Hauptthema: Neue Infektionskrankheiten

Author

Lüthy, R., zum Büschenfelde, K.-H. Meyer, Hengels, K. J., Strohmeyer, G., Lode, H., Höffken, G., Schaberg, T., Herzer, P., Herzer, K.-H. Meyer zum, Göbel, U. B., ter Meulen, V., and Miehlke, Klaus, editor

Published
1991
Full Text
View/download PDF

2. AIDS 1991

Author

Goebel, F.-D., Pohle, H. D., Mertens, Th., Knechten, H., Habets, L., Knickmann, M., Wolters, D., Hess, G., Lüthy, R., Gürtler, L. G., Kurth, R., Binninger, D., Ennen, J., Denner, J., Hartung, S., Norley, S., and Miehlke, Klaus, editor

Published
1991
Full Text
View/download PDF

20. Computer-controlled in-vitro simulation of multiple dosing regimens

Author

Ledergerber, B., Blaser, J., Lüthy, R., Ledergerber, B., Blaser, J., and Lüthy, R.

Abstract

The bactericidal effect of gentarrucin on Pseudomonas aeruginosa ATCC 27853 was investigated in a computer controlled dynamic in-vitro model, which allows the simultaneous simulation of three different dosing regimens for several days. The same total dose reduced cfu-counts of Pseudomonas aeruginosa most effectively, when administered with peak concentrations of 32 mg/l every 32 h, whereas the other dosing regimens with peak concentrations of 16 mg/l every 16 h and 8 mg/l every 8 h were distinctly less effective following the second and subsequent doses. It was shown that the use of a microcomputer facilitates the in-vitro investigation of multiple dosing regimens but counting of cfu cannot be substituted by automatic measurements of turbidity when rapid bactericidal effects occur

Published
2017

21. Serological diagnosis of Q fever endocarditis

Author

DUPUIS, G., PÉTER, O., LÜTHY, R., NICOLET, J., PEACOCK, M., BURGDORFER, W., DUPUIS, G., PÉTER, O., LÜTHY, R., NICOLET, J., PEACOCK, M., and BURGDORFER, W.

Abstract

The diagnosis of Q fever endocarditis cannot be made by bacterial cultures and necessitates serological identification of specific antibodies to Coxiella burnetii which stimulates mainly the production of anti-phase II antibodies during the acute diséase, but primarily anti-phase I antibodies in endocarditis. Indirect micro-immunofluorescence allows rapid detection of specific IgA, IgG and IgM. The results of serological analyses of 191 acute cases of Q fever were compared with those of 8 cases of Coxiella burnetii endocarditis. All sera were evaluated by complement fixation and microimmunofluorescence tests. The highest titre differences between primary Q fever and Q fever endocarditis were observed with anti-phase IIgA and IgG antibodies measured by microimmunofluorescence followed by anti-phase I antibodies measured by complement fixation tests. Anti-phase IIgG and IgM titres were consistently higher than anti-phase II titres in endocarditis. The reverse is true in acute Q fever. In addition, anti-phase I Ig A appeared to be diagnostic for Coxiella burnetii endocarditis. Accordingly we recommend the testing of these specific IgA, IgG, and IgM by microimmunofluorescence in cases of culture-negative endocarditis. These tests could also prove useful for following the development of Coxiella burnetii endocarditis in patients under treatment

Published
2017

22. Human pharmacology of 5-epi-sisomicin (Sch 22591) following intramuscular administration

Author

Blaser, J., M¨nch, R., Lüthy, R., Blaser, J., M¨nch, R., and Lüthy, R.

Abstract

5-epi-sisomicin was given as a single intramuscular injection of 1 mg/kg to six healthy male adults. Serum peak concentrations averaged 3.07 mg/l, the mean elimination half life was 179 min and the mean 24 h urinary recovery was 85.3%. Local and systemic tolerance was good

Published
2017

26. Postersession VI : Infektionskrakheiten

Author

Gärtner, U., Gundert-Remy, U., Theilmann, L., Hampl, B., Czygan, P., Kommerell, B., Höffken, G., Tetzel, H., Koeppe, P., Lode, H., Kaue, I., Kemmerich, B., Borner, K., Wagner, J., Ledergerber, B., Hugentobler, A., Lüthy, R., Anliker, M., Menge, H., Skubis, R., Simes, G., Hahn, H., Riecken, E. O., Vogel, G. E., Bottermann, P., Fresenius, K., Komm, Ch., Präuer, W., Oberdorfer, A., Tsambaos, D., Orfanos, C. E., Krämer, A., Ehrlicher, L., Zeichhardt, H., Coester, C.-H., Dalhoff, K., Dennin, R., Schulz, E., Sack, K., Hoyer, J., Niebel, J., Kellhammer, U., Gerhartz, H. H., Sauerbruch, T., Weinzierl, M., Ruckdeschl, G., Trautmann, M., Fischer, G. I., Hofstaetter, Th., Seiler, F. R., Kather, H., Aktories, K., Miehlke, Klaus, editor, and Bergmann, J. F.

Published
1984
Full Text
View/download PDF

28. Die Endokarditis als interdisziplinäres Problem

Author

Nager, F., Hort, W., Naumann, P., Rosin, H., Bolte, H.-D., Jenni, R., Büsser, M., Turina, M., Lüthy, R., Frick, W., Siegenthaler, W., Lode, H., Schröder, R., Glauser, M. P., Malinverni, R., Francioli, P., Täuber, M. G., Chambers, H. F., Rothlin, M. E., Miehlke, Klaus, editor, and Bergmann, J. F.

Published
1984
Full Text
View/download PDF

40. Book reviews

Author

Neppert, J., Wagner, H. P., Mueller-Eckhardt, C., Leibold, W., Kubanek, B., Lüthy, R., Bauer, H., Müller-Berghaus, G., Schrör, K., Dörmer, P., and Albert, E.

Published
1985
Full Text
View/download PDF

44. Progression of HIV infection in misusers of injected drugs who stop injecting or follow a programme of maintenance treatment with methadone

Author

Opravil M, Lüthy R, Bruno Ledergerber, Rainer Weber, and Walter Siegenthaler

Subjects
Adult, CD4-Positive T-Lymphocytes, Male, Drug, medicine.medical_specialty, Time Factors, media_common.quotation_subject, HIV Infections, Asymptomatic, Cohort Studies, Risk Factors, Cause of Death, Internal medicine, Confidence Intervals, Humans, Medicine, Outpatient clinic, Life Tables, Substance Abuse, Intravenous, Proportional Hazards Models, General Environmental Science, media_common, Cause of death, business.industry, Proportional hazards model, General Engineering, General Medicine, Middle Aged, Prognosis, Surgery, Relative risk, General Earth and Planetary Sciences, Female, medicine.symptom, business, Methadone, Research Article, medicine.drug, Cohort study
Abstract

OBJECTIVE--To see whether misusers of injected drugs who stop injecting or switch to a programme of maintenance treatment with methadone have a reduced risk of progression of HIV infection when compared with a group of persistent misusers. DESIGN--Observational cohort study in HIV seropositive subjects with a current or past history of misusing injected drugs. SETTING--HIV outpatient clinic at the University Hospital of Zurich, Switzerland. PATIENTS--297 Current and former parenteral drug misusers (median age 27) with asymptomatic HIV infection. During the observation period 80 subjects adhered to a programme of maintenance treatment with methadone, 124 continued with parenteral drug misuse, and 93 former misusers remained free of illicit drugs. No antiretroviral treatment was given during the study. MAIN OUTCOME MEASURES--Probability of progression of HIV infection from asymptomatic to symptomatic (Centers for Disease Control stage IV) as calculated by life table analysis and compared in the three groups of patients by means of a log rank test, and predictors of disease progression as analysed with a Cox proportional hazards regression model. RESULTS--The 297 patients were followed up for a median of 16 months. The median duration of injecting drug misuse before enrollment was 7.1 years. There were no significant differences among the three groups with respect to CD4+ counts at the beginning of the study (median 0.44 x 10(9)/l). Life table analysis showed a significantly lower probability of progression of HIV disease in both the methadone treated group and former drug misusers than in persistent injecting drug misusers. Multivariate regression analysis showed a relative risk of progression of the disease of 1.78 (95% confidence interval 1.20 to 2.67; p less than 0.01) in persistent injecting drug misusers, 0.48 (0.29 to 0.77; p less than 0.01) in the methadone treated group, and 0.66 (0.41 to 1.06; p = 0.085) in former drug misusers. CONCLUSIONS--Stopping the misuse of injected drugs slows the progression of HIV disease in infected subjects. Drug treatment programmes are effective in secondary prevention of HIV associated morbidity.

Published
1990

48. 1. Podiumsgespräch

Author

Lüthy, R., primary, Knothe, H., additional, Lode, H., additional, Stalder, H., additional, and Stille, W., additional

Published
1984
Full Text
View/download PDF

50. Postersession VI

Author

Gärtner, U., primary, Gundert-Remy, U., additional, Theilmann, L., additional, Hampl, B., additional, Czygan, P., additional, Kommerell, B., additional, Höffken, G., additional, Tetzel, H., additional, Koeppe, P., additional, Lode, H., additional, Kaue, I., additional, Kemmerich, B., additional, Borner, K., additional, Wagner, J., additional, Ledergerber, B., additional, Hugentobler, A., additional, Lüthy, R., additional, Anliker, M., additional, Menge, H., additional, Skubis, R., additional, Simes, G., additional, Hahn, H., additional, Riecken, E. O., additional, Vogel, G. E., additional, Bottermann, P., additional, Fresenius, K., additional, Komm, Ch., additional, Präuer, W., additional, Oberdorfer, A., additional, Tsambaos, D., additional, Orfanos, C. E., additional, Krämer, A., additional, Ehrlicher, L., additional, Zeichhardt, H., additional, Coester, C.-H., additional, Dalhoff, K., additional, Dennin, R., additional, Schulz, E., additional, Sack, K., additional, Hoyer, J., additional, Niebel, J., additional, Kellhammer, U., additional, Gerhartz, H. H., additional, Sauerbruch, T., additional, Weinzierl, M., additional, Ruckdeschl, G., additional, Trautmann, M., additional, Fischer, G. I., additional, Hofstaetter, Th., additional, Seiler, F. R., additional, Kather, H., additional, and Aktories, K., additional

Published
1984
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results