39 results on '"L.R. Braathen"'
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2. Long methylaminolaevulinate application does not increase clinical efficacy of photodynamic therapy in actinic keratosis, but leads to collateral damage
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L.R. Braathen
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medicine.medical_specialty ,Photosensitizing Agents ,Keratosis ,business.industry ,medicine.medical_treatment ,Actinic keratosis ,Treatment outcome ,Photodynamic therapy ,Aminolevulinic Acid ,Dermatology ,Photosensitizing Agent ,medicine.disease ,Keratosis, Actinic ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Treatment Outcome ,0302 clinical medicine ,Photochemotherapy ,Collateral damage ,Humans ,Medicine ,Clinical efficacy ,business - Published
- 2017
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3. Health economy in dermatology
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L.R. Braathen
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Medical education ,Economics ,business.industry ,MEDLINE ,Health Care Costs ,Dermatology ,Health economy ,Congresses as Topic ,Europe ,Infectious Diseases ,Humans ,Medicine ,business ,Societies, Medical - Published
- 2018
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4. European Hair Research Society 12th Annual Meeting
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Azizeh Afkham-Ebrahimi, M. Carmen González-Vela, Tadashi Terui, Wen-Jun Liao, Tian-Wen Gao, Hachiro Tagami, Emilio Rodrigo, J.N. Bouwes Bavinck, Ramon M. Pujol, E. Dupont, Lisette Stucki, M. Andrien, M. Borner, P. Elsner, Ana Ferrer, M. Hidajat, Ping-Shen Fan, T. Hunziker, Meng Fu, Bernard Cribier, Shigaku Ikeda, U. Buettiker, Razieh Soltani-Arabshahi, Nanny van Geel, P.J. Coenraads, D. Linder, Martin Leverkus, Jean Naeyaert, Christian Deligant, Pietro Dri, T. Diepgen, Marcos A. González-López, G.G. Tscharner, Ryuhei Okuyama, Audrey Mitschler, M. Keller, C. Marques Da Costa, Fernando Gallardo, M. Song, Veronica Baena, W.J. Pichler, J. Fernando Val-Bernal, J.J. Stene, Edouard Grosshans, Dan Lipsker, Setsuya Aiba, Marta Ferran, Axel Trautmann, Héctor Fernández-Llaca, Luigi Naldi, Yu-Feng Liu, Lourdes Florensa, H.C. Williams, Chris Vervaet, L.R. Braathen, Å. Svensson, M. van der Cruys, J.J. Grob, S. Bühler, Katia Ongenae, Najmossadat Atefi, Anja Gesierich, S.M. Langan, Yukikazu Numata, Leigh Martin, Vincent Piguet, Yves Vander Haeghen, Christian Rose, Eva-Bettina Bröcker, Nikhil Yawalkar, Shu Sasai, Manuel A. Arias-Rodríguez, L. Naldi, and Roberto Manfrini
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medicine.medical_specialty ,business.industry ,Family medicine ,medicine ,Dermatology ,business - Published
- 2006
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5. Acute Generalized Exanthematic Pustulosis: A Case and an Overview of Side Effects Affecting the Skin Caused by Celecoxib and Other COX-2 Inhibitors Reported So Far
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B. Goeschke and L.R. Braathen
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musculoskeletal diseases ,medicine.medical_specialty ,Dermatology ,Diagnosis, Differential ,Dermis ,Edema ,Humans ,Medicine ,Cyclooxygenase Inhibitors ,heterocyclic compounds ,Leukocytosis ,Sulfonamides ,biology ,business.industry ,Arthritis ,Exanthema ,Middle Aged ,Acute generalized exanthematous pustulosis ,medicine.disease ,Pustulosis ,medicine.anatomical_structure ,Celecoxib ,Face ,Anesthesia ,Toxicity ,Arm ,biology.protein ,Pyrazoles ,Female ,Drug Eruptions ,Cyclooxygenase ,medicine.symptom ,business ,medicine.drug - Abstract
A 55-year-old woman who was treated for periarthritis humeroscapularis with celecoxib (Celebrex) developed a generalized pustular exanthema on the head and upper trunk, accompanied by fever, leukocytosis and increased erythrocyte sedimentation rate. The histological findings were subcorneal pustules, necrotic keratinocytes, edema in the upper dermis and polymorphic perivascular infiltrates. Four days after stopping celecoxib, the pustules disappeared without any treatment. Four weeks after disappearance of the skin lesions, celecoxib demonstrated a positive lymphocyte stimulation test. In this article, we present to our knowledge the first case of acute generalized exanthematic pustulosis caused by celecoxib, and we give an overview of the side effects affecting the skin caused by celecoxib and other cyclooxygenase type 2 inhibitors reported so far.
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- 2004
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6. 84th Annual Meeting of the Swiss Society for Dermatology and Venereology
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L.R. Braathen
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Dermatology - Published
- 2002
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7. Satellite Symposium at the 7th Congress of the European Academy of Dermatology and Venereology, Nice, October 9, 1998
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E. Stockfleth, C.R. de Potter, T. Rufli, J. Lambert, D. Zillikens, L.R. Braathen, G. Piérard, T. Lahaye, M. Song, M. de la Brassinne, G.E. Piérard, J.E. Arrese, Ch.C. Zouboulis, E. Christophers, G.L. Capella, Y. Sasaki, L. Sponagel, Y. Sadamoto, L Segura Puertas, F. Brouers, F.H.J. van den Hoogen, H. Degreef, M. Heenen, T. Nishikawa, S. de Mare, M. Bauwens, M. Inada, J.-M. Schröder, A.J. Kanwar, S. Yamada, T. Pohle, S. Magina, P. Itin, S. Dhar, I. Uhoda, S. Malakar, J. Drewe, C. Hernandez-Pion, C. Degraeve, R. Cecchi, N. Lateur, C. Fracchiolla, T.A. Luger, A. Alomar, I. Antunes, U. Sass, B. Meinke, K. Higuchi, R. Brehler, T. Hermanns-Lê, R.E. Hunger, P. Bisschop, J.M. Lachapelle, B. Coessens, R. Taberner, C. Piérard-Franchimont, P. Paquet, C.U. Brand, M. Sticherling, J.M. Naeyaert, J. Senneseael, R. Arndt, M. Anseeuw, D. Roseeuw, R.M. Pujol, J. André, F. Henry, I. Fumal, R. Lemos, G.P. Thami, J. Mesquita-Guimarães, S. Wustlich, O. Neofotistou, K. Kato, T. Koga, C. Diaz, E.-C. Foerster, U. van Haelst, G. Altomare, T. Meyer, C. Nadal, N.P. Stratigeas, A. Hubert, P. Gheeraert, M. Furue, Y. Abe, N. Gyr, M. Cassé, J. Miralles, M. Imamura, A. De Coninck, A. Giomi, A.L. Fraiture, J.-Ch. Noël, J.W. Burnett, B.E. Paredes, S. Courvoisier, M.M.B. Seyger, A.C. Katoulis, V. Goeteyn, E.M.G.J. de Jong, E. Heimer de la Cotera, M.A. Barros, H. Dhivert-Donnadieu, R. Kuroki, P. Dupuy, A. Looks, O. Heymans, H. Shimizu, D. Lange, E. Granjo, A. Theunis, J. Fissette, S. Blacher, N.A. Schaub, A. Elíseo, W. Domschke, U. Wollina, N.G. Stavrianeas, A. Jortay, M. Médot, C. Neamonitos, F. André, B. Heykarts, J. Pinton, E. Bornscheuer, L. Gilli, E. Frigerio, and M. Battegay
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medicine.medical_specialty ,Venereology ,business.industry ,Ophthalmology ,medicine ,Library science ,Nice ,Dermatology ,business ,computer ,computer.programming_language - Published
- 1999
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8. Contents, Vol. 195, 1997
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S.B. Margulis, C. Mann, M.L. Battifoglio, E. Ranieri, J. Yeager, A. Stoehr, Dan Lipsker, R. Viraben, H.G. Skelton, M. Stücker, R. Betti, E. Inselvini, S. Reichert-Penetrat, L.R. Braathen, J. Hafiier, G. Claus, C. Ferrándiz, I. Hadshiew, A. Fujioka, I.K. Hornstra, J. Bazex, A. Friedl, C. Crosti, M. Hiruma, E. Hölzle, F. Drago, H. Laubenthal, B. Couret, I. Bielsa, A. von Felten, E.M. Procaccini, D. Abeck, A. Bonnafoux-Clavere, E.A. Bingham, P.M. Frossard, T. Hunziker, J.M. Carrascosa, J. Rousseau, J. Rügemer, S. Untiedt, P. Clavere, M. Palvarini, W.Y.M. Tang, Philippe Tréchot, Subrata Malakar, E. Weisshaar, T. Reuther, L. Maunoury, A. Reborn, K. Nomura, G. Posteraro, F. Malaguti, A. Traub, S. Palacios, M. Chishiki, R.B. Strieker, F. Stäb, E. Martinez, D.K.B. Armstrong, C. Letawe, E. Piqué, E. Adeghate, J.L. Laporte, H. Gollnick, M. Monika Weber, J.-F. Cuny, K.J. Smith, A. Ishibashi, I. Hashimoto, G.G. Lestringant, J.C. Piette, M.-P. Labarthe, L. Casula, I.H. Galadari, P. Chavaz, C.T. Ammirati, A.W. Gerbig, G. von Kohyletzki, V. Roman, C. Bedane, A. Plettenberg, Gérald Pierard, V. Goffin, P. Bayle-Lebey, W. Meigel, M. Gfesser, H. Banba, K. Bohnsack, M.F. Peake, J.L. Wilde, Akira Kawada, M. Just, Annick Barbaud, E. Losi, P. Hügler, I. Masouyé, Sandipan Dhar, M. Olivares, Jean-Luc Schmutz, K. Hoffmann, M. Ribera, M.A. Hurhi, F. Rippke, M. Gallego, G. Riccio, Jean-Hilaire Saurat, R.B. Lee, R. Disch, J.M. Bonnetblanc, A. Aguilar, J.J. Meffert, Camille Francès, P. Altmeyer, E. Masgrau, G. Monfrecola, K.F. Wagner, J. Ring, B. Gorguet, Lars E. French, and V. Schreiner
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Dermatology - Published
- 1997
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9. Contents, Vol. 193, 1996
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D.I. Roseeuw, G. Kozel, B. Mevorah, C.W. Lee, A.S. van Strubarq, J.-H. Saurat, G. Lorette, U. Haustein, M.C. Machet, Linares Barrios, F. Lamprecht, Castaño Suárez, A. Sotto, L.R. Braathen, M. Iijima, E.M.G.J. de Jong, H.-J. Yu, T. Kato, H. Tagami, J. Smolle, G. Schmid-Ott, J.M. Bonnetblanc, D. Hohl, S.D. Mariz, Sanchez Conejo-Mir, P.C.M. van de Kerkhof, K. Holubar, C. Münzberger, M.H. Park, Corbí Llopis, A.-M. Calza, D. Bessis, T. Suetake, A. De Coninck, S. Bohn, C. Bedane, G.E. Píérard, C.Q Wen, A. Velasco, Navarrete Ortega, M. Iwata, G. Barnéon, C. Vezzani, C. Royer, Casals Andreu, T. Yoshida, F. Otsuka, H.Y. Yang, A. Caliens, M.S. Guidetti, P.H. Itin, L. Machet, D. Salomon, H.W. Kuensebeck, M. Haidvogl, R. Ott, J.T. Kainz, V. Jan, T. Zuberbier, Suárez Fernández, Enríquez de Salamanca, H. Sueki, B.A.M.P.A. Seegers, P. Lecomte, P.I. Schiller, M.K. Gulinck, Y. Gall, C.U. Brand, E. Trippas, C. Ishizaki, J.B.M. Boezeman, S.-C. Kim, C.K. Park, S. Iijima, J.H. Cho, J.P. Farcet, M. Krasovec, E. Frenk, T. Oguro, A. Tosti, Rojo Sánchez, D. Mathys, G. Richard, M. Berson, B.M. Henz, Robledo Aguilar, D. Guggisberg, E.T. Suys, B. Burtin, Zamarro Sanz, H. Han, R. Guggenheim, Ph. Ruffieux, Sanchez de Paz, López Bran, M.A. Pipeleers-Marichal, L. Vaillant, Guerra Tapia, J.-J. Guilhou, C. Stinchi, E.M. Studer, B. Jaeger, A. Hernández-Martín, Artola Igarza, E. de Eusebio Murillo, M. Armijo, E. Aoki, and L.R Huyghens
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Dermatology - Published
- 1996
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10. Contents, Vol. 191, 1995
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Y. Shigenaga, M. Harms, I. Masouyé, B. Didona, R. Happle, E. Svejgaard, T. Kanzaki, A. Fiedler, P. Elsner, C. Willa-Craps, J.-H. Saurat, L. Didierjean, J. Sayag, G. Dawn, R. Hoffmann, P.H. Itin, C. Gelmetti, H.C. Korting, I. Braide, I. Ikeda, H. Ogawa, P.A. Piletta, R. Schultheiss, M. Yoshioka, M.C. Koeppel, E. Frenk, M. Yamazaki, T. Ono, T. Hisa, C. Mazzanti, C. Angeli-Besson, J.-M. Geiger, T. Kageshita, M.-H. Schmid, T. Fukumitsu, A.J. Kanwar, U.-F. Haustein, S. Ullman, P. Fileccia, D. Hohl, M.A. Fernández-Pugnaire, S. Mizoguchi, C. Nishikawa, C.R. Çelebi, T. Hamada, N. Kürkçüoğlu, T. Hunziker, T. Gobello, L. Andrac, R. Ammann, D. Guggisberg, V. Delgado-Florencio, S. Dhar, K. Rosén, K. Unno, M. Yssing, S. Cambiaghi, T. Rufli, T. Horio, C. Remondat, G. Scarabelli, B. Vion, H. Yaguchi, G. Pistritto, H. Miyauchi, P. Jacquet, A.M. Calza, C. Bertrand, G. Burg, S.A. Buechner, T. Karlsmark, I. Katayama, C. Hansson, C. Schepis, T. Yamamoto, M. Pechère, F. Atzori, K. Nishioka, R. Cavalieri, R. Tsuboi, N. Illum, M. Takigawa, P. Nenoff, M. Papi, M. Siragusa, Y. Hirachi, M. Setoyama, L.R. Braathen, and P. Blecher
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Dermatology - Published
- 1995
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11. Contents, Vol. 189, 1994
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G. Burg, D. Czarnecki, T. Würsch, L.R. Braathen, D. Salomon, P.H. Itin, P.A. Fanti, C.G. Schirren, R. Feldmann, P. Elsner, C. Bonifati, L. Czirják, G. Santagostino, L. Gilli, W. Stolz, H. Schirren, L. Zala, M. Laporte, R. Wolf, R. Flückiger, C. Varotti, E. Pócs, A. Tosti, E. Frenk, D. Parent, T. Rufli, M. Fazio, C. Surber, M. Pietravalle, A.J. Sober, Y. Miki, D.E. Müller, A. Mar, P. Tu, G. Kaplanski, S.A. Büchner, O. Matsuda, M. Heenen, G. Szegedi, S. Miyauchi, S. Lautenschlager, M.C. Koeppel, R. Frei, R.D. Juch, K.T. Holland, J.-H. Saurat, S.L. Karvonen, R. Zbinden, B. Triquet, P. Morier, R. Ketterer, C. Deharo, J. Sayag, O. Avci, P. Ruffieux, J. Fäh, K. Holubar, J.M. Durand, N. Hato, N.H. Shear, G. Orecchia, A.K. Gupta, G. Giles, C. Mainetti, W.J. Cunliffe, J. Hatzis, C.M. Betts, J. Decroix, G. Plewig, M.L. Cucchi, C. Meehan, M. Staples, Jr. Falo L.D., S. Shiraishi, D. Hohl, F. Bardazzi, J. Karvonen, F. Ameglio, S.R. Knowles, L. Andrac, T. Reunala, S. Brenner, R.L. Barnhill, P. Kind, K. Sayama, P. Frattini, L. Räsänen, and A.T. Güneş
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Dermatology - Published
- 1994
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12. Livedo racemosa: A Report of Five Cases
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L. Zala and L.R. Braathen
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Adult ,Male ,medicine.medical_specialty ,Pathology ,Adolescent ,Arteriosclerosis ,Arterial disease ,Dermatology ,Skin Diseases, Vascular ,Antiphospholipid syndrome ,Humans ,Medicine ,Child ,Aged ,Embolism, Cholesterol ,business.industry ,Livedo vasculitis ,Vascular disease ,Polyarteritis nodosa ,Thrombosis ,Cerebral Infarction ,Syndrome ,Livedo racemosa ,Antiphospholipid Syndrome ,medicine.disease ,Polyarteritis Nodosa ,body regions ,Female ,Sneddon's syndrome ,medicine.symptom ,business - Abstract
We present 5 patients in whom the diagnosis of livedo racemosa gave rise to clinical and laboratory investigations revealing arterial disease of different etiologies. This presentation emphasizes the importance of not missing the clinical diagnosis of livedo racemosa.
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- 1994
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13. Photodynamic therapy: increasing acceptance through reduction of adverse reactions
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L.R. Braathen
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Male ,Clobetasol ,medicine.medical_specialty ,Keratosis ,business.industry ,medicine.medical_treatment ,Photodynamic therapy ,Dermatology ,medicine.disease ,Keratosis, Actinic ,Reduction (complexity) ,Scalp Dermatoses ,Humans ,Medicine ,Female ,business ,Glucocorticoids ,Facial Dermatoses - Published
- 2014
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14. Contents, Vol. 187, 1993
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A. Chang, Dj. Polić, E. Frenk, J. Hafner, L. Zala, L. Hommel, B.M. Lalević-Vasić, D. Van Neste, M. Pippione, F. Pasche-Koo, M.P. Labarthe, C. Tomasini, J. Tercedor, M. Harms, S. Ghosh, F. Aloi, A. Bon, B. Wüthrich, M.A. López-Nevot, T. Okuwa, M. Skiljo, R. Guggenheim, M. Monteit, M.M. Nikolić, U. Bühler, S. Dhar, P.-A. Piletta, P.C.M. van de Kerkhof, C. Mainetti, H.I. Maibach, R. Flückiger, A.J. Kanwar, C.J. Witkop, J.-H. Saurat, L. Borradori, R. Ketterer, J.M. Wood, C. Schmied, M.K. Kägi, T. Hunziker, A. Huszar, A. Shafik, P. Ruffieux, J. Perriard-Wolfensberger, D. Salomon, A. Azón-Masoliver, E. Massare, E. Garcia-Lora, G. Burg, J. Singh, V. Garcia-Mellado, S.A. Büchner, A. Eichmann, L.R. Braathen, J.B.M. Boezeman, S. Kaur, I.M.J.J. van Vlijmen-Willems, J. Vilaplana, P.H. Itin, D. Hohl, T. Kitajima, S. Imamura, L.S. Wolfe, B. Radosavljević, and K.U. Schallreuter
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Dermatology - Published
- 1993
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15. Contents Vol. 200, 2000
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L.R. Braathen, Tsutomu Fujimura, M. Barten, Konstanze Spieth, C. Seipp, Paul L. Bigliardi, J.-H. Saurat, Roland Kaufmann, M. Derighetti, Antonio Del Sorbo, W. Bodemer, R. Zimmermann, Tokihiko Shimada, C.U. Brand, P. Rohner, Hans-Joachim Schulz, S. Aractingi, P. Reygagne, R.G. Panizzon, Shoko Shimada, Y.X. Zhen, M. Laporte, M.V. Kuipers, M. Böhm, D. de Hoop, Yoshinori Takema, Roland Böni, Elvira Masturzo, M. Streit, J.F. Silvestre, Kazunari Usuki, B.E. Paredes, Genji Imokawa, D. Guggisberg, A. Etienne, J.-P. Cerottini, C. Bachmeyer, I. Betlloch, J. Bañuls, S. Lu, B. Ninet, L. Toutous-Trellu, Uwe Wollina, M. Tanaka, D. Fokan, M. Pechère, G. Bonsmann, Oliver P Kreyden, Günter Burg, M. Fathi, Kazue Tsukahara, Shigeru Moriwaki, K. O’Goshi, N. Tabata, S. Rüegger, K. Biel, Francesco Borgia, S. Krähenbühl, Rudolf Happle, Jens Gille, R. Botella, A.M. Kligman, R.E. Hunger, S. Miyakawa, T.A. Luger, Thomas Zaugg, Andreas J. Bircher, H. Tagami, Jürg Meyer, Serafinella P. Cannavò, Walter H.C. Burgdorf, P.C.M. van de Kerkhof, Mario Vaccaro, C. de Graef, Biagio Guarneri, S.A. Cobelens, R. Ramón, R. Auckenthaler, B. Krayenbühl, P.-A. Piletta, Giuseppe Monfrecola, Jann Lübbe, Mitsuhiro Sekiyama, C. Quattroppani, M. Grimaître, Soili Mäkinen-Kiljunen, Tim Graefe, G. Burg, G. Gross, C. Ostwald, Reinhard Dummer, D. Hohl, J. Navas, J. de Korte, Anna Maria Riccardo, S. Shimizu, P. Galand, W.Y.M. Tang, A. Pires, Tamotsu Kanzaki, B. Noël, K. Buxtorf, M. Heenen, B.H. Krayenbühl, and Takashi Kitahara
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Dermatology - Published
- 2000
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16. Subject Index Vol. 191,1995
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C. Gelmetti, T. Ono, T. Karlsmark, T. Fukumitsu, L. Andrac, T. Hisa, M. Pechère, N. Kürkçüoğlu, S. Ullman, G. Burg, T. Hunziker, T. Gobello, T. Horio, T. Kanzaki, P.A. Piletta, S. Cambiaghi, K. Unno, C. Remondat, M. Takigawa, K. Rosén, C. Nishikawa, P. Nenoff, G. Scarabelli, M. Yoshioka, K. Nishioka, J.-M. Geiger, T. Kageshita, A.J. Kanwar, U.-F. Haustein, L. Didierjean, F. Atzori, M. Papi, M.A. Fernández-Pugnaire, G. Dawn, M. Yamazaki, M. Siragusa, M.C. Koeppel, S. Dhar, M. Setoyama, L.R. Braathen, V. Delgado-Florencio, T. Rufli, I. Katayama, Y. Hirachi, C. Mazzanti, P. Elsner, G. Pistritto, D. Hohl, N. Illum, P. Blecher, P. Jacquet, J. Sayag, E. Frenk, R. Hoffmann, A.M. Calza, I. Braide, I. Ikeda, P. Fileccia, R. Cavalieri, M.-H. Schmid, T. Hamada, H. Ogawa, H.C. Korting, R. Schultheiss, R. Tsuboi, C. Angeli-Besson, C. Schepis, D. Guggisberg, H. Yaguchi, C.R. Çelebi, C. Hansson, T. Yamamoto, A. Fiedler, Y. Shigenaga, B. Didona, E. Svejgaard, C. Willa-Craps, P.H. Itin, M. Harms, I. Masouyé, S. Mizoguchi, R. Happle, J.-H. Saurat, R. Ammann, H. Miyauchi, C. Bertrand, S.A. Buechner, M. Yssing, and B. Vion
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Index (economics) ,Statistics ,Subject (documents) ,Dermatology ,Mathematics - Published
- 1995
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17. Childhood epidermolysis bullosa acquisita
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H. Gerber, P. Inauen, Th. Hunziker, Leena Bruckner-Tuderman, and L.R. Braathen
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Male ,Epidermolysis bullosa acquisita ,Pathology ,medicine.medical_specialty ,Prednisolone ,Fluorescent Antibody Technique ,Dermatology ,Epidermolysis Bullosa Acquisita ,Basement Membrane ,Anchoring fibrils ,medicine ,Herpetiform ,Humans ,Child ,Autoantibodies ,Autoimmune disease ,Basement membrane ,Mucous Membrane ,integumentary system ,business.industry ,Mouth Mucosa ,Autoantibody ,Mucous membrane ,medicine.disease ,medicine.anatomical_structure ,Immunoglobulin G ,Drug Therapy, Combination ,Epidermolysis bullosa ,business ,Dapsone - Abstract
We report a 6-year-old boy suffering from acquired epidermolysis bullosa, who presented with extensive lesions of the mucous membranes and disseminated, herpetiform and 'cluster of jewels'-like vesicles and bullae arising on erythematous plaques. Direct immunofluorescence showed linear deposits of IgG and C3 at the epidermal basement membrane zone. Indirect immunofluorescence demonstrated circulating autoantibodies (titre 1:128-1:256) directed at the blister floor of human NaCl-split skin, and reacting specifically with collagen VII of the anchoring fibrils, as demonstrated by immunoblotting. The disease was controlled with a combination of dapsone and prednisone. This case demonstrates the importance of modern immunological techniques in classifying childhood autoimmune bullous diseases, as precise diagnosis is important in determining an appropriate therapeutic regimen.
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- 1994
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18. Latent infection of epidermal Langerhans cells in HIV-positive individuals
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G. Ramirez, L.R. Braathen, R.O.F. Kunze, O. Strand, and C. Mork
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Adult ,Male ,Langerhans cell ,medicine.drug_class ,Immunology ,Phosphatase ,Human immunodeficiency virus (HIV) ,Biology ,medicine.disease_cause ,Monoclonal antibody ,Staining technique ,Peripheral blood mononuclear cell ,Virology ,HIV Seropositivity ,medicine ,Humans ,Cells, Cultured ,Monocyte ,virus diseases ,medicine.anatomical_structure ,Langerhans Cells ,Alkaline phosphatase ,Female ,Epidermis - Abstract
Epidermal cell suspension otained fron 3 symptom-free HIV-positive individuals were cultured and marked with monoclonal antibodies for the HIV proteins p15, p24 and gp120 in the alkaline phosphatase anti-alkaline phosphatase staining technique. For 2 individuals, cells were positive after 3 days in culture, and for the third, after 4 days. Supernatant from one of the cultures infected allogeneic peripheral blood mononuclear cells. We conclude that epidermal Langerhans cells from symptom-free HIV-positive individuals are latent-infected and are able to produce and release HIV.
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- 1991
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19. Pigmentation following long-term bismuth therapy for pneumatosis cystoides intestinalis
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L.R. Braathen, L. Zala, and Thomas Hunziker
- Subjects
inorganic chemicals ,medicine.medical_specialty ,chemistry.chemical_element ,Dermatology ,Eccrine Glands ,digestive system ,Basement Membrane ,Bismuth ,Pneumatosis Cystoides Intestinalis ,medicine ,Humans ,Pigmentation disorder ,Aged ,medicine.diagnostic_test ,business.industry ,Bismuth poisoning ,bacterial infections and mycoses ,equipment and supplies ,medicine.disease ,Hyperpigmentation ,digestive system diseases ,chemistry ,Skin biopsy ,Gingival Diseases ,Female ,medicine.symptom ,business ,Mouth Diseases ,Pigmentation Disorders ,Facial Dermatoses - Abstract
In the recent literature, only a few reports deal with generalized pigmentation caused by bismuth treatment. We report a patient developing generalized pigmentation of the skin and mucous membranes without further signs of chronic bismuth poisoning following long-term administration of bismuth for pneumatosis cystoides intestinalis. Bismuth deposits were documented in a skin biopsy.
- Published
- 1993
20. Subject Index Vol. 202, 2001
- Author
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B. Hermes, S. Kawana, W.H.C. Burgdorf, B Lecewicz-Toruń, Kristien De Paepe, T. Takano, Vera Rogiers, Diane Roseeuw, C. Gianni, Konstantine Buxtorf, K. Nomura, Consuelo Greco, Jean-Pierre Hachem, B.M. Henz, K.H. Holubar, M. Harms, Robert Baran, C. Hildenbrand, Francesco Drago, Phung M. Huynh, Y. Kimura, S. Läuchli, Paolo Rampini, Ulrich Binswanger, K. Suzuki, J. Brinckmann, Aldona Pietrzak, Jean-Hilaire Saurat, N. Zakopoulou, Amilcare Cerri, Jong-Sub Moon, Eugen Hübscher, Frank O. Nestle, Leonard Kaufman, Michael Meurer, M. Alexander, Manuela Papini, Naveed Sami, Mariateresa Semino, Gurvinder P. Thami, G.L. Vecchietti, Roberta Calcaterra, Antonio Guiducci, Magali Berset, P. Chavaz, A. Razzaque Ahmed, J.P. Cerottini, Paola Braidotti, J. Fäh, A.M. Matta, A. Friedli, Sukhjot Kaur, C. Tschanz, Jürg Hafner, Gürkan Kaya, F. Livio, L. Widmer, Rudolf Happle, A. Matsuyama, Dorota Krasowska, Amrinder J. Kanwar, M. Aoki, Alfred Eichmann, Jean L. Bolognia, W. Löntz, S. Takezaki, A. Hürlimann, T. Tuchida, Els Vanpée, N. Haas, Somesh Gupta, K. Buxtorf, Valeria Morelli, Christa Prins, P. Agache, Günther F.L. Hofbauer, S. Lautenschlager, S. Mary, M. Mock, G.J. Kontochristopoulos, Enrico Rampini, P. Muret, P. Humbert, M. Derighetti, I. Masouyé, Reinhard Dummer, E. Holle, M. Streit, Patrizia Rossini, R.G. Panizzon, Y. Kikuchi, Rossitza Lazova, Chil-Hwan Oh, Werner Kempf, A. Skaria, Anne-Kathrin Tausche, L.M. Böhlen, D. Salomon, Severin Läuchli, R.M. Trüeb, M. Tronnier, L.R. Braathen, E.C. Alexandropoulos, Günter Burg, and Renato G. Panizzon
- Subjects
Index (economics) ,Statistics ,Subject (documents) ,Dermatology ,Mathematics - Published
- 2001
- Full Text
- View/download PDF
21. Contents Vol. 202, 2001
- Author
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P. Humbert, I. Masouyé, Naveed Sami, Günther F.L. Hofbauer, S. Lautenschlager, L. Widmer, A.M. Matta, Gürkan Kaya, C. Gianni, E. Holle, Christa Prins, L.M. Böhlen, Dorota Krasowska, Vera Rogiers, L.R. Braathen, Kristien De Paepe, Consuelo Greco, T. Takano, Aldona Pietrzak, Somesh Gupta, Anne-Kathrin Tausche, Leonard Kaufman, Paolo Rampini, S. Kawana, P. Agache, Paola Braidotti, K. Suzuki, J.P. Cerottini, C. Hildenbrand, Jean-Pierre Hachem, C. Tschanz, Jürg Hafner, Y. Kimura, W. Löntz, Michael Meurer, Amilcare Cerri, Gurvinder P. Thami, Phung M. Huynh, S. Mary, Antonio Guiducci, Els Vanpee, M. Harms, B. Hermes, B.M. Henz, N. Zakopoulou, Eugen Hübscher, J. Brinckmann, G.J. Kontochristopoulos, Sukhjot Kaur, M. Aoki, Severin Läuchli, K. Buxtorf, Alfred Eichmann, Jean L. Bolognia, M. Alexander, Manuela Papini, W.H.C. Burgdorf, B Lecewicz-Toruń, N. Haas, Diane Roseeuw, M. Derighetti, G.L. Vecchietti, S. Takezaki, Robert Baran, Rudolf Happle, Magali Berset, S. Läuchli, Jean-Hilaire Saurat, Roberta Calcaterra, Ulrich Binswanger, Jong-Sub Moon, Frank O. Nestle, Reinhard Dummer, Patrizia Rossini, Mariateresa Semino, F. Livio, D. Salomon, Francesco Drago, T. Tuchida, Y. Kikuchi, Rossitza Lazova, Chil-Hwan Oh, Enrico Rampini, Renato G. Panizzon, A. Skaria, Werner Kempf, Konstantine Buxtorf, K. Nomura, Amrinder J. Kanwar, P. Chavaz, Valeria Morelli, A. Friedli, E.C. Alexandropoulos, R.G. Panizzon, M. Streit, M. Mock, P. Muret, R.M. Trüeb, M. Tronnier, A. Razzaque Ahmed, J. Fäh, K.H. Holubar, A. Matsuyama, A. Hürlimann, and Günter Burg
- Subjects
Dermatology - Published
- 2001
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- View/download PDF
22. Subject Index Vol. 200, 2000
- Author
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L.R. Braathen, B. Ninet, S. Rüegger, R. Auckenthaler, D. de Hoop, D. Guggisberg, Tokihiko Shimada, J. Bañuls, S. Aractingi, Soili Mäkinen-Kiljunen, R.E. Hunger, D. Fokan, M. Fathi, T.A. Luger, S. Miyakawa, C. Bachmeyer, Jürg Meyer, M. Tanaka, Andreas J. Bircher, I. Betlloch, Francesco Borgia, S.A. Cobelens, Kazunari Usuki, B.H. Krayenbühl, Yoshinori Takema, W. Bodemer, Uwe Wollina, R. Botella, A.M. Kligman, H. Tagami, G. Bonsmann, Walter H.C. Burgdorf, B.E. Paredes, Genji Imokawa, Roland Böni, R. Ramón, B. Noël, Shoko Shimada, C. de Graef, R. Zimmermann, M. Böhm, M. Heenen, K. Biel, J. de Korte, C. Ostwald, B. Krayenbühl, S. Lu, Oliver P Kreyden, Kazue Tsukahara, Günter Burg, W.Y.M. Tang, C. Seipp, M. Derighetti, Konstanze Spieth, J.F. Silvestre, Y.X. Zhen, P.C.M. van de Kerkhof, Giuseppe Monfrecola, Elvira Masturzo, Reinhard Dummer, D. Hohl, J.-P. Cerottini, Anna Maria Riccardo, S. Shimizu, P. Galand, M. Grimaître, J. Navas, N. Tabata, L. Toutous-Trellu, K. O’Goshi, G. Burg, G. Gross, Serafinella P. Cannavò, Mitsuhiro Sekiyama, A. Pires, Thomas Zaugg, Roland Kaufmann, C. Quattroppani, P.-A. Piletta, M. Laporte, C.U. Brand, Shigeru Moriwaki, P. Rohner, Hans-Joachim Schulz, R.G. Panizzon, Mario Vaccaro, Biagio Guarneri, M. Barten, S. Krähenbühl, J.-H. Saurat, M. Streit, A. Etienne, Jens Gille, Tim Graefe, Jann Lübbe, Takashi Kitahara, K. Buxtorf, Tsutomu Fujimura, Paul L. Bigliardi, Tamotsu Kanzaki, Antonio Del Sorbo, M. Pechère, Rudolf Happle, M.V. Kuipers, and P. Reygagne
- Subjects
Index (economics) ,Statistics ,Subject (documents) ,Dermatology ,Mathematics - Published
- 2000
- Full Text
- View/download PDF
23. HIV Infection of Skin Langerhans Cells
- Author
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C. Mørk and L.R. Braathen
- Subjects
Aids patients ,Arc (protein) ,integumentary system ,business.industry ,Human immunodeficiency virus (HIV) ,virus diseases ,Mucous membrane ,medicine.disease_cause ,Peripheral blood mononuclear cell ,Membrane ,medicine.anatomical_structure ,Immunology ,Medicine ,Binding site ,business - Abstract
Human Langerhans cells in the skin and mucous membranes may play an important role in the HIV infection. They carry CD4 molecules which serve as a binding site for HIV, and HIV-infected Langerhans cells have been demonstrated in the skin of ARC/AIDS patients.
- Published
- 1991
- Full Text
- View/download PDF
24. Acknowledgment to Referees for Dermatology 1997
- Author
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G. Riccio, Jean-Hilaire Saurat, A. Ishibashi, F. Rippke, C. Letawe, I. Bielsa, A. von Felten, G.G. Lestringant, M.-P. Labarthe, Philippe Tréchot, I.H. Galadari, I.K. Hornstra, M. Gallego, Camille Francès, M. Ribera, S. Untiedt, M. Palvarini, J. Rügemer, G. von Kohyletzki, A. Bonnafoux-Clavere, E.A. Bingham, M. Monika Weber, A. Aguilar, P.M. Frossard, C. Mann, T. Hunziker, M.A. Hurhi, W.Y.M. Tang, A. Stoehr, M.L. Battifoglio, T. Reuther, P. Clavere, G. Posteraro, J. Ring, Sandipan Dhar, S. Reichert-Penetrat, E. Inselvini, A. Traub, S. Palacios, J. Hafiier, A. Reborn, L. Maunoury, C. Ferrándiz, M. Olivares, E. Hölzle, J. Bazex, R.B. Strieker, F. Drago, P. Altmeyer, H.G. Skelton, A. Friedl, J.J. Meffert, G. Claus, K. Hoffmann, R. Betti, E. Masgrau, E. Piqué, J.M. Carrascosa, B. Gorguet, E.M. Procaccini, I. Masouyé, R.B. Lee, R. Disch, B. Couret, J. Rousseau, S.B. Margulis, P. Chavaz, C.T. Ammirati, K. Nomura, F. Malaguti, Jean-Luc Schmutz, D. Abeck, H. Laubenthal, H. Gollnick, J.M. Bonnetblanc, H. Banba, K. Bohnsack, A.W. Gerbig, A. Plettenberg, Gérald Pierard, V. Goffin, J.L. Laporte, Akira Kawada, G. Monfrecola, I. Hashimoto, P. Bayle-Lebey, Dan Lipsker, Subrata Malakar, K.F. Wagner, R. Viraben, P. Hügler, J.C. Piette, W. Meigel, J. Yeager, Lars E. French, F. Stäb, V. Schreiner, L.R. Braathen, E. Adeghate, C. Crosti, V. Roman, E. Weisshaar, E. Martinez, D.K.B. Armstrong, I. Hadshiew, A. Fujioka, L. Casula, M. Gfesser, M. Chishiki, C. Bedane, M.F. Peake, J.L. Wilde, M. Just, Annick Barbaud, E. Losi, J.-F. Cuny, K.J. Smith, E. Ranieri, M. Stücker, and M. Hiruma
- Subjects
medicine.medical_specialty ,business.industry ,Family medicine ,Medicine ,Dermatology ,business - Published
- 1997
- Full Text
- View/download PDF
25. Acknowledgment to Referees for Dermatology 1996
- Author
-
U. Haustein, C. Bedane, L. Machet, A. Sotto, G. Lorette, M. Berson, P.C.M. van de Kerkhof, Robledo Aguilar, D. Guggisberg, K. Holubar, D.I. Roseeuw, B. Mevorah, D. Hohl, Ph. Ruffieux, Sanchez de Paz, López Bran, M.A. Pipeleers-Marichal, M. Iwata, E. de Eusebio Murillo, J. Smolle, H. Sueki, J.H. Cho, A. Velasco, C.U. Brand, J.-H. Saurat, E.T. Suys, Navarrete Ortega, C.Q Wen, M.C. Machet, A. Hernández-Martín, J.P. Farcet, M. Krasovec, D. Salomon, G. Richard, E. Trippas, A. Caliens, P.H. Itin, P. Lecomte, S. Iijima, M. Iijima, M. Haidvogl, J.B.M. Boezeman, L.R. Braathen, H.-J. Yu, G. Schmid-Ott, G.E. Píérard, E. Frenk, Casals Andreu, V. Jan, D. Mathys, M. Armijo, T. Oguro, Suárez Fernández, G. Barnéon, C. Vezzani, S. Bohn, H. Tagami, C.W. Lee, A. Tosti, Guerra Tapia, A. De Coninck, S.D. Mariz, T. Yoshida, E. Aoki, Linares Barrios, Y. Gall, L.R Huyghens, B. Burtin, P.I. Schiller, J.M. Bonnetblanc, C. Münzberger, M.H. Park, Sanchez Conejo-Mir, Zamarro Sanz, S.-C. Kim, T. Kato, H.Y. Yang, H. Han, C.K. Park, R. Ott, F. Otsuka, D. Bessis, T. Suetake, M.K. Gulinck, Corbí Llopis, A.-M. Calza, C. Ishizaki, Artola Igarza, B.A.M.P.A. Seegers, Rojo Sánchez, C. Royer, H.W. Kuensebeck, E.M.G.J. de Jong, G. Kozel, L. Vaillant, M.S. Guidetti, B.M. Henz, J.T. Kainz, F. Lamprecht, R. Guggenheim, J.-J. Guilhou, C. Stinchi, Castaño Suárez, E.M. Studer, B. Jaeger, T. Zuberbier, Enríquez de Salamanca, and A.S. van Strubarq
- Subjects
medicine.medical_specialty ,business.industry ,Family medicine ,Medicine ,Dermatology ,business - Published
- 1996
- Full Text
- View/download PDF
26. Subject Index Vol. 193, 1996
- Author
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C.W. Lee, A. Hernández-Martín, H.Y. Yang, H. Sueki, E.M. Studer, T. Zuberbier, G. Kozel, R. Ott, Enríquez de Salamanca, Guerra Tapia, Linares Barrios, Robledo Aguilar, D. Guggisberg, Ph. Ruffieux, Sanchez de Paz, B. Jaeger, López Bran, E. Trippas, G. Barnéon, M.A. Pipeleers-Marichal, A.S. van Strubarq, G. Lorette, C. Vezzani, Castaño Suárez, U. Haustein, T. Yoshida, L.R. Braathen, A. De Coninck, J.M. Bonnetblanc, J.-H. Saurat, H.-J. Yu, Sanchez Conejo-Mir, G. Richard, M.C. Machet, D. Hohl, A. Sotto, P.C.M. van de Kerkhof, C. Royer, J.B.M. Boezeman, Navarrete Ortega, S.D. Mariz, P. Lecomte, C. Bedane, J. Smolle, J.-J. Guilhou, Corbí Llopis, A.-M. Calza, M. Haidvogl, D. Mathys, G.E. Píérard, C.Q Wen, B.A.M.P.A. Seegers, F. Lamprecht, C. Stinchi, L. Machet, Y. Gall, M. Berson, C. Ishizaki, S. Bohn, K. Holubar, D.I. Roseeuw, B. Mevorah, F. Otsuka, C. Münzberger, M.H. Park, M. Iwata, H.W. Kuensebeck, H. Tagami, D. Salomon, B.M. Henz, R. Guggenheim, Rojo Sánchez, E.T. Suys, L. Vaillant, V. Jan, P.I. Schiller, B. Burtin, Zamarro Sanz, H. Han, C.K. Park, M. Armijo, E. Aoki, L.R Huyghens, A. Velasco, A. Caliens, P.H. Itin, Suárez Fernández, Artola Igarza, E. de Eusebio Murillo, C.U. Brand, J.H. Cho, J.P. Farcet, M. Krasovec, M. Iijima, G. Schmid-Ott, T. Kato, Casals Andreu, M.S. Guidetti, J.T. Kainz, D. Bessis, T. Suetake, S.-C. Kim, S. Iijima, E. Frenk, T. Oguro, A. Tosti, M.K. Gulinck, and E.M.G.J. de Jong
- Subjects
Index (economics) ,Statistics ,Subject (documents) ,Dermatology ,Mathematics - Published
- 1996
- Full Text
- View/download PDF
27. Topical Photodynamic Therapy in Verrucae
- Author
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L.R. Braathen, R. Ammann, and T. Hunziker
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Photodynamic therapy ,Dermatology ,eye diseases ,Refractory ,medicine ,Photosensitizer ,Red light ,business ,Complete response ,Amino-Levulinic Acid - Abstract
Background : Topical photodynamic therapy (PDT) has shown good response rates in solar keratoses and superficial skin cancers. Objective : To investigate the efficiency and tolerance of PDT in refractory verrucae vulgares. Method : In an open pilot study, 6 patients were treated with 5-aminolevulinic acid-PDT and followed up for 2 months. Result : One patient showed a complete response, the other 5 patients were treatment failures. Conclusion : Topical PDT is probably not efficient in treating verrucae vulgares.
- Published
- 1995
- Full Text
- View/download PDF
28. Subject Index Vol. 189,1994
- Author
-
L. Gilli, G. Szegedi, R. Frei, L. Räsänen, J. Sayag, R. Ketterer, C. Meehan, F. Ameglio, P. Elsner, C. Bonifati, W.J. Cunliffe, A.T. Güneş, D.E. Müller, R. Flückiger, Jr. Falo L.D., N. Hato, L. Zala, S. Shiraishi, N.H. Shear, P. Kind, L.R. Braathen, S.A. Büchner, P. Frattini, D. Salomon, J. Hatzis, J. Karvonen, S. Lautenschlager, K. Sayama, R.D. Juch, M. Fazio, C. Deharo, W. Stolz, T. Rufli, S.R. Knowles, M. Laporte, G. Kaplanski, T. Reunala, S. Miyauchi, A.K. Gupta, C. Surber, J.M. Durand, K.T. Holland, K. Holubar, C. Varotti, D. Parent, S.L. Karvonen, J.-H. Saurat, S. Brenner, R.L. Barnhill, D. Hohl, F. Bardazzi, M. Pietravalle, A.J. Sober, L. Andrac, A. Mar, P. Morier, G. Orecchia, P. Tu, T. Würsch, O. Matsuda, M. Heenen, C.M. Betts, J. Decroix, G. Plewig, M.L. Cucchi, M. Staples, M.C. Koeppel, O. Avci, P. Ruffieux, R. Wolf, J. Fäh, G. Giles, C. Mainetti, L. Czirják, C.G. Schirren, G. Santagostino, P.H. Itin, Y. Miki, H. Schirren, B. Triquet, R. Zbinden, E. Pócs, A. Tosti, E. Frenk, P.A. Fanti, R. Feldmann, G. Burg, and D. Czarnecki
- Subjects
Index (economics) ,Statistics ,Subject (documents) ,Dermatology ,Mathematics - Published
- 1994
- Full Text
- View/download PDF
29. Chronic Cutaneous Infection Caused by Mycobacterium gordonae
- Author
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L.R. Braathen, L. Zala, and Thomas Hunziker
- Subjects
biology ,medicine.diagnostic_test ,business.industry ,Mycobacterium gordonae ,Dermatology ,Skin infection ,medicine.disease ,biology.organism_classification ,Microbiology ,hemic and lymphatic diseases ,Biopsy ,Medicine ,business ,Mycobacterium - Abstract
We report on a patient with a chronic nodular cutaneous infection histologically presenting with tuberculoid granulomas and growing Mycobacterium gordonae in culture from a biopsy. The lesions were treated surgically. M. gordonae is a potentially pathogenic environmental mycobacterium only rarely causing skin infections.
- Published
- 1993
- Full Text
- View/download PDF
30. Langerhans cells and the skin immune system
- Author
-
L.R. Braathen
- Subjects
Infectious Diseases ,Immune system ,business.industry ,Immunology ,Medicine ,Dermatology ,business ,Histiocyte - Published
- 1998
- Full Text
- View/download PDF
31. C056 Langerhans cells and the skin immune system
- Author
-
L.R. Braathen
- Subjects
Infectious Diseases ,Immune system ,business.industry ,Immunology ,Medicine ,Dermatology ,business ,Histiocyte - Published
- 1997
- Full Text
- View/download PDF
32. Acknowledgement to Referees for Dermatology 1994
- Author
-
R. Wolf, R. Ketterer, G. Santagostino, P.H. Itin, M. Staples, R. Flückiger, A. Mar, G. Burg, L. Zala, P. Frattini, P. Elsner, R. Zbinden, M. Fazio, H. Schirren, G. Szegedi, S.R. Knowles, G. Kaplanski, D. Czarnecki, D.E. Müller, C. Bonifati, J. Hatzis, E. Pócs, A. Tosti, E. Frenk, R. Frei, L. Gilli, C. Meehan, Jr. Falo L.D., S. Shiraishi, K.T. Holland, L. Czirják, J.-H. Saurat, D. Hohl, F. Bardazzi, J. Karvonen, B. Triquet, M.C. Koeppel, M. Heenen, S.A. Büchner, P. Morier, S. Brenner, L.R. Braathen, Y. Miki, R.L. Barnhill, D. Salomon, S.L. Karvonen, F. Ameglio, P. Kind, S. Lautenschlager, P.A. Fanti, C.G. Schirren, R. Feldmann, R.D. Juch, T. Rufli, W. Stolz, C. Deharo, M. Laporte, T. Reunala, S. Miyauchi, A.K. Gupta, G. Giles, C. Mainetti, C. Varotti, D. Parent, M. Pietravalle, A.J. Sober, K. Holubar, N. Hato, N.H. Shear, O. Avci, P. Ruffieux, J. Fäh, J.M. Durand, G. Orecchia, C. Surber, P. Tu, K. Sayama, O. Matsuda, L. Räsänen, A.T. Güneş, L. Andrac, J. Sayag, C.M. Betts, J. Decroix, G. Plewig, T. Würsch, M.L. Cucchi, and W.J. Cunliffe
- Subjects
Medical education ,Acknowledgement ,Dermatology ,Psychology - Published
- 1994
- Full Text
- View/download PDF
33. The effect of short-term corticosteroid incubation on the alloactivating and antigen-presenting capacity of human epidermal Langerhans cells
- Author
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H. Hirschberg and L.R. Braathen
- Subjects
medicine.medical_specialty ,Langerhans cell ,Hydrocortisone ,Cell Survival ,T-Lymphocytes ,medicine.medical_treatment ,Antigen presentation ,Dermatology ,Biology ,Lymphocyte Activation ,Tuberculin ,Methylprednisolone ,Monocytes ,Antigen ,Internal medicine ,medicine ,Humans ,Cells, Cultured ,Dose-Response Relationship, Drug ,Epidermis (botany) ,T lymphocyte ,Steroid hormone ,Endocrinology ,medicine.anatomical_structure ,Langerhans Cells ,Glucocorticoid ,medicine.drug - Abstract
Summary The effects of short-term incubation with hydrocortisone and methylprednisolone on the alloactivating capacity and the ability of human epidermal Langerhans cells and peripheral blood monocytes to induce antigen (PPD)-specific T-lymphocyte responses were investigated. The Langerhans cells and the monocytes were treated with different concentrations of the steroids before being added to allogeneic T lymphocytes, and before, after or simultaneously with, pulsing with PPD. Neither steroid inhibited the alloactivating capacity of the Langerhans cells, but a dose-dependent reduction of the stimulatory capacity of antigen-pulsed Langerhans cells and monocytes was obtained with methylprednisolone. Hydrocortisone had inhibitory effects only at high concentration. The inhibition appeared to be due to suppression of the presentation of PPD in immunogeneic form to sensitized T cells.
- Published
- 1984
- Full Text
- View/download PDF
34. Immunological in situ identification of the lymphoid cells in the skin infiltrate of lichen planus
- Author
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L.R. Braathen, B.‐L. Dal, and O.J. Mellbye
- Subjects
In situ ,Antiserum ,Pathology ,medicine.medical_specialty ,Indirect immunofluorescence ,integumentary system ,T-Lymphocytes ,Lichen Planus ,Immune adherence ,Skin infiltrate ,Fluorescent Antibody Technique ,Dermatology ,Complement factor I ,Biology ,stomatognathic diseases ,Tissue sections ,medicine ,Humans ,Receptor ,Skin - Abstract
Summary A specific rabbit anti-human T-lymphocyte antiserum has been used in an indirect immunofluorescence technique to identify T lymphocytes in situ in tissue sections from lichen planus skin lesions. T lymphocytes were also identifiedin situ by means of aminoethylisothiouronium bromide-treated sheep red blood cells, using an immune adherence technique. Various types of coated sheep red blood cells were utilized to detect cells with receptors for FcIgG and complement factor C3b. The results demonstrated the presence of predominantly T lymphocytes, and probably some macrophages and few B lymphocytes in the skin infiltrate of lichen planus. Total and differential white count as well as relative and absolute numbers of B and T lymphocytes in peripheral blood were also determined, and found to be within the normal range.
- Published
- 1979
- Full Text
- View/download PDF
35. Class and subclass distribution of specific antibodies to codfish allergen in a patient with atopic allergy
- Author
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T. Lea, L.R. Braathen, and T. Moen
- Subjects
Dermatology ,General Medicine - Abstract
Using an indirect ELlSA technique together wilh rabbit antisera specific for human immunoglobulin classes and lgG subclasses, an estimate was made of the contribution of immunoglobulin classes and subclasses to the overall antibody response against codfish allergen in serum from a patient allergic to codfish. Allergen-specific antibodies were found to be of immunoglobulin classes lgM, lgD and lgE and the subclasses IgG1, lgG3 and IgG4. No antibodies of lgA class or lgG2 subclass were present. High levels of lgG3 and lgD were found.
- Published
- 1980
- Full Text
- View/download PDF
36. UVC irradiation of human epidermal Langerhans cells decreases the alloactivating and antigen presenting capacity
- Author
-
N.‐J. Mork, L.R. Braathen, and H. Borufsen
- Subjects
Langerhans cell ,Epidermis (botany) ,Ultraviolet Rays ,T-Lymphocytes ,T cell ,Tuberculin ,Dose-Response Relationship, Radiation ,Dermatology ,T lymphocyte ,Biology ,Molecular biology ,Suction blister ,medicine.anatomical_structure ,Antigen ,Langerhans Cells ,Immunopathology ,Immunology ,medicine ,Humans - Abstract
Summary Human epidermal cells (Ec) obtained with a suction blister technique and enzyme digestion, were irradiated with various doses of UVC. They were then co-cultured with allogeneic T cells or pulsed with the soluble antigen, purified protein derivative of tuberculin (PPD), for 90 min before being cocultured with autologous T cells. The allogeneic T cell responses were reduced with UVC in a dose-dependent fashion while increasing numbers of EC increased the responses to allo-antigens. The PPD-specific T cell response was reduced with UVC in a dose-dependent manner and this reduction seemed to be stronger than the reduction in the alloactivating ability. Increasing numbers of EC increased the PPD-specific T cell response. No difference was found in the number of DR-positive cells before or immediately after irradiation with various doses of UVC.
- Published
- 1988
- Full Text
- View/download PDF
37. Langerhans cells as primary target cells for HIV infection
- Author
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H. Gelderblom, L.R. Braathen, R. O. F. Kunze, and G. Ramirez
- Subjects
Acquired Immunodeficiency Syndrome ,Primary (chemistry) ,business.industry ,Langerhans Cells ,Human immunodeficiency virus (HIV) ,Medicine ,HIV ,Humans ,General Medicine ,business ,medicine.disease_cause ,Virology - Published
- 1987
38. In Vitro Infection of Human Epidermal Langerhans Cells with HIV
- Author
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L.R. Braathen, R. O. F. Kunze, G. Ramirez, and H. Gelderblom
- Subjects
MHC class II ,Lineage (genetic) ,biology ,Antigen ,Epidermis (botany) ,Antigen presentation ,biology.protein ,Receptor ,Molecular biology ,Peripheral blood mononuclear cell ,In vitro - Abstract
Human epidermal Langerhans cells (Lc) play an important role in antigen presentation and immunoregulation in the skin (for review see ref.(1)).They carry antigens and receptors which are identical to those of classical macrophages, i.e. FcIgG, C3 and the MHC class II HLA-D/DR antigens (2,3),but also the T-cell markers CDKT6) and CD4(T4) (4–6). Remarkably, Lc exhibit 50-fold higher amounts of HLA-DR than other cells of the monocyte-macrophage lineage (7).
- Published
- 1988
- Full Text
- View/download PDF
39. Human epidermal Langerhans cells induce cellular immune response to trichophytin in dermatophytosis
- Author
-
L.R. Braathen and T. Kaaman
- Subjects
Antiserum ,Immunity, Cellular ,integumentary system ,Macrophages ,T-Lymphocytes ,Histocompatibility Antigens Class II ,Trichophytin ,Dermatology ,HLA-DR Antigens ,Biology ,Immunofluorescence staining ,Lymphocyte Activation ,Molecular biology ,Immune system ,Langerhans Cells ,Immunology ,Dermatomycoses ,Humans - Abstract
SUMMARY Human epidermal cell suspensions were prepared from patients sensitized to trichophytin. The cells were 75% to 95% viable, and contained 2% to 6% Langerhans cells as judged by immunofluorescence staining with an anti-DR antiserum. T lymphocytes from the same patients were co-cultured with trichophytin, with or without epidermal cells or macrophages. Proliferative T-cell response to trichophytin was obtained in cultures containing epidermal cells or macrophages. Pretreatment of the epidermal cells with anti-DR antiserum abolished the response, but normal rabbit serum did not, indicating that HLA-DR positive Langerhans cells are able to induce the cellular immune response to trichophytin. These data indicate that Langerhans cells play an important role in dermatophytosis.
- Published
- 1983
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