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The paper introduced design of a real-time pressure monitoring system of fully mechanized working face taking 120204 fully mechanized working face of Yangchangwan Coal Mine as example. According to parameters of pressure of front prop, back prop and front beam of each support collected by pressure monitoring units, the system can give quantitative analysis results through analysis software of surface host, namely pressure change of front prop, back prop and front beam of support, working performance of prop, frequency distribution of circulation resistance of prop, roof pressure distribution; the system can analyze relation between pressure change of support and breaking result of top coal according to analysis results of working performance of prop, so as to provide evidence for improving efficiency of top coal caving. The actual application showed that the system has perfect functions and can reflect process of pressure change of working face effectively.

whether killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigens C (HLA-C) are associated with HLA-B27 associated acute anterior uveitis (B27AAU) and idiopathic AAU (IAAU) remains unclear. PCR with sequence-specific primers was used to analyze KIR genes and HLA-C alleles in a Chinese Han population of 196AAU patients and 210 control subjects. The higher frequencies of HLA-C2 and KIR2DL1/HLA-C2 (p =.009 and p =.044, respectively) and the lower frequencies of HLA-C1C1 and HLA-C1 (p =.034 and p =.009, respectively) were observed in B27AAU than control group. The higher frequencies of KIR2DL2 and KIR2DL2/HLA-C1 (p =.009 and p =.044, respectively) and the lower frequencies of KIR2DL3 and KIR2DL3/HLA-C1 (p =.000 and p =.001, respectively) were observed in IAAU than control group. HLA-C2 and KIR2DL1/HLA-C2, KIR2DL2, and KIR2DL2/HLA-C1 might be susceptible for B27AAU and IAAU, respectively. HLA-C1C1 and HLA-C1, KIR2DL3 and KIR2DL3/HLA-C1 might protect from B27AAU and IAAU, respectively. [ABSTRACT FROM AUTHOR]

Purpose: whether the Killer immunoglobulin-like receptor (KIR) genotypes and haplotypes are associated with the improvement in dry eye disease (DED) patients treated with Restasis and Systane (RS) remain unclear.Methods: Polymerase chain reaction with sequence-specific primers (PCR-SSP) was used to analyze KIR genes in a Chinese Han population of 198 severe DED patients treated with RS.Results: The higher frequencies of KIR genotype M, AF, AJ and haplotype 2 and 8 (P = .001, P = .03, P = .004, P = .000 and P = .023, respectively) and the lower frequencies of genotype AG and haplotype 1 (P = .000 and P = .000, respectively) were observed in complete responders (CR) than those in null or partial responders (NPR) of DED patients treated by RS.Conclusions: The patients with KIR genotype M, AF and AJ might be of advantage to therapy with RS, which are useful for improving novel personalized precise therapy strategy in DED patients. [ABSTRACT FROM AUTHOR]