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The slow interconversion of [FeIII(TF4TMAP)(H2O)2]5+ and [FeIII(TF4TMAP)OH]4+ takes place mainly through bimolecular reaction between the aqua and hydroxo forms with k = 1.6 x 10(supra6) M-1 s-1 (298 K) and Ea = 6.7 plus or minus 0.4 kcal mol-1. Exchange of a proton, motion of the iron into or out of the porphyrin plane and addition or loss of a coordinated water are all involved in the interconversion between [FeIII(TF4TMAP)OH]4+ and [FeIII(TF4TMAP)(H2O)2]5+.

Nickel tetrakis(N-methyl-4-pyridiniumyl)porphyrin(NiT4-N-MePyP4+) was shown to bind axial bonds more strongly than nickel tetrakis(2,3,5,6-tetrafluoro-N,N,N-trimethyl-4-aniliniumyl)-porphyrin (NiTF4TMAP+). Solution chemistry and crystal structure of the complexes revealed that the four coordinate (NiT4-N-MePyP4+) is in equilibrium with the six coordinate Ni(H2O)2TF4-TMAP4+ in aqueous solution and creates a hydrophobic effect, which strengthens porphyrin interactions in the solution.

Objective: To evaluate characteristics, training, and self-reported skills and abilities in vision and ocular care among PAs not specializing in ophthalmology., Methods: A survey on PA practice was administered to 5,763 randomly selected US-based PAs, and 537 respondents who completed the survey were invited to complete a separate vision and ocular care survey. Of those respondents, 382 completed the vision and ocular care survey., Results: Among respondents, 23% of PAs were involved in eyecare by providing patient information, answering questions, and initiating discussions about vision care and ocular health more than once per month. More than 77% received vision and ocular care training in and/or outside PA training. PAs involved in eyecare had significantly greater odds of reporting higher desired and current skill and ability levels compared with PAs not involved in eyecare, in six of eight vision and ocular care domains., Conclusions: PAs who do not practice in ophthalmology provide vision and ocular care but have varying amounts of training and desire higher skill and ability levels. Ophthalmologists and PA institutions may develop vision and ocular care training for PA schools and continuing medical education., (Copyright © 2022 American Academy of Physician Assistants.)