1. Labdane diterpenes from Cistus symphytifolius
- Author
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Cosme G. Francisco, Ernesto Suárez, Manuel Cortés, Rosendo Hernández, M. T. Calabuig, Ministerio de Asuntos Exteriores y Cooperación (España), and Comisión Asesora de Investigación Científica y Técnica, CAICYT (España)
- Subjects
Labdanolic acid ,Stereochemistry ,Cistus symphytifolius ,Salvic acid ,Plant Science ,Cistaceae ,Labdane diterpenes ,Horticulture ,Biochemistry ,Labdane ,chemistry.chemical_compound ,Cistadienic acid ,Organic chemistry ,Labdenic acid ,Molecular Biology ,Cativic acid ,labdan-8α,15-diol ,Bicyclic molecule ,biology ,Trimethoxykaempferol ,General Medicine ,biology.organism_classification ,Sitosterol ,labd-13(E)-ene-8α-15-diol ,chemistry ,Jara ,Enantiomer ,Cistenolic acid - Abstract
4 pages., The investigation of the aerial part of Cistus symphytifolius afforded, in addition to sitosterol, trimethoxykaempferol, cativic acid, labdenic acid, labdanolic acid and labdan-8α,15-diol, three new bicyclic diterpenes: cistadienic acid, cistenolic acid and labd-13(E)- ene-8α,15-diol. The structures of these were determined by spectral studies and correlations. CD spectral studies showed that cistenolic acid and salvic acid are enantiomeric compounds, so the stereochemistry of salvic acid (7α-hydroxy-labd-8(17)-ene-15-oic acid) should be changed to 7β-hydroxy-eperu-8(17)-ene-15-oic acid (7β-hydroxy-ent-labd-8(17)-ene-15-oic acid)., Part of this work was subsidized by the Comisión Asesora de Investigación Científica y Técnica. M.C. wishes to thank the Centro Iberoamericano de Cooperación of Spain for a fellowship.
- Published
- 1981
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