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2. Prevalence of Dengue, Chikungunya and Zika Viruses in Blood Donors in the State of Pará, Northern Brazil: 2018–2020

Author

Lamarão, Leticia Martins, primary, Corrêa, Angelita Silva Miranda, additional, de Castro, Renata Bezerra Hermes, additional, de Melo Amaral, Carlos Eduardo, additional, Monteiro, Patricia Danin Jordão, additional, Palmeira, Mauricio Koury, additional, Lopes, Luane Nascimento, additional, Oliveira, Angela Neves, additional, de Lima, Maria Salete Maciel, additional, Moreira-Nunes, Caroline Aquino, additional, and Burbano, Rommel Rodríguez, additional

Published
2022
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5. First isolation of enterovirus 71 (EV-71) from Northern Brazil

Author

Lamarão Leticia Martins, Maciel Ana Maria T. R., and Gomes Maria de Lourdes Contente

Subjects
Enterovirus-71, neurological disease, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
Abstract

Enterovirus 71 (EV-71) has been associated to cases of neurological disease in many countries including Brazil. This virus has now been reported from three of the five Brazilian regions. Our study relates the findings concerning to the first isolate of this virus in Northern region of Brazil. A 15-month old female patient, from the rural zone of the municipality of Santana do Araguaia in southern Pará state was admitted at the hospital with acute, flaccid, asymmetric and ascending motor deficiency, located in the right lower limb. Stools samples from this child were inoculated in RD cells and was isolated an EV-71. We plan to sequence our strain and compare it to other isolates in Brazil. Differences at the molecular level can explain why EV-71 strains circulating in other continents, such as Asia, appear to be more virulent.

Published
2003

6. Prevalence of Dengue, Chikungunya and Zika Viruses in Blood Donors in the State of Pará, Northern Brazil: 2018–2020.

Author

Lamarão, Leticia Martins, Corrêa, Angelita Silva Miranda, de Castro, Renata Bezerra Hermes, de Melo Amaral, Carlos Eduardo, Monteiro, Patricia Danin Jordão, Palmeira, Mauricio Koury, Lopes, Luane Nascimento, Oliveira, Angela Neves, de Lima, Maria Salete Maciel, Moreira-Nunes, Caroline Aquino, and Burbano, Rommel Rodríguez

Subjects
CHIKUNGUNYA virus, ZIKA virus, BLOOD donors, DENGUE viruses, DENGUE, DENGUE hemorrhagic fever
Abstract

Arboviruses have been reported over the years as constant threats to blood transfusion recipients, given the high occurrence of asymptomatic cases and the fact that the presence of viremia precedes the onset of symptoms, making it possible that infected blood from donors act as a source of dissemination. This work aims to identify the prevalence of dengue virus (DENV), Zika virus (ZIKV) and Chikungunya virus (CHIKV) infection in blood donors during epidemic and non-epidemic periods; classify the donor as symptomatic or asymptomatic; and verify the need to include DENV, CHIKV and ZIKV in the nucleic acid test (NAT) platform in northern Brazil. We investigated 36,133 thousand donations in two years of collection in Northern Brazil. One donor was positive for DENV and one for CHIKV (0.002% prevalence). As the prevalence for arboviruses was low in this study, it would not justify the individual screening of samples from donors in a blood bank. Thus, DENV- and CHIKV-positive samples were simulated in different amounts of sample pools, and both were safely detected by molecular biology even in a pool of 14 samples, which would meet the need to include these three viruses in the routine of blood centers in endemic countries such as Brazil. [ABSTRACT FROM AUTHOR]

Published
2023
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7. Detection of Sepsis in Platelets Using MicroRNAs and Membrane Antigens

Author

Vieira Corrêa, Priscilla Cristina Moura, primary, Carneiro, Débora Monteiro, additional, da Silva Valente, Luciana do Socorro, additional, Diogo, Fabíola Marques, additional, Lamarão, Leticia Martins, additional, da Silva Maués, Jersey Heitor, additional, Moreira-Nunes, Caroline Aquino, additional, and Burbano, Rommel Mario Rodríguez, additional

Published
2021
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8. Prevalence of Dengue Virus, Chikungunya and Zika Infection in Blood Donors of Northern of Brazil

Author

Lamarão, Leticia Martins, primary, Corrêa, Angelita Silva Miranda, additional, de Castro, Renata Bezerra Hermes, additional, Amaral, Carlos Eduardo de Melo, additional, Monteiro, Patricia Danin Jordão, additional, Palmeira, Mauricio Koury, additional, Lopes, Luane Nascimento, additional, Oliveira, Angela Neves, additional, de Lima, Maria Salete Maciel, additional, and Burbano, Rommel Rodríguez, additional

Published
2021
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9. PD-L1 Expression Associated with Epstein—Barr Virus Status and Patients’ Survival in a Large Cohort of Gastric Cancer Patients in Northern Brazil

Author

de Fátima Aquino Moreira-Nunes, Caroline, primary, de Souza Almeida Titan Martins, Cláudia Nazaré, additional, Feio, Danielle, additional, Lima, Isamu Komatsu, additional, Lamarão, Leticia Martins, additional, de Souza, Carolina Rosal Teixeira, additional, Costa, Igor Brasil, additional, da Silva Maués, Jersey Heitor, additional, Soares, Paulo Cardoso, additional, de Assumpção, Paulo Pimentel, additional, and Burbano, Rommel Mário Rodríguez, additional

Published
2021
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10. YWHAE silencing induces cell proliferation, invasion and migration through the up-regulation of CDC25B and MYC in gastric cancer cells: new insights about YWHAE role in the tumor development and metastasis process

Author

Leal, Mariana Ferreira, primary, Ribeiro, Helem Ferreira, additional, Rey, Juan Antonio, additional, Pinto, Giovanny Rebouças, additional, Smith, Marília Cardoso, additional, Moreira-Nunes, Caroline Aquino, additional, Assumpção, Paulo Pimentel, additional, Lamarão, Leticia Martins, additional, Calcagno, Danielle Queiroz, additional, Montenegro, Raquel Carvalho, additional, and Burbano, Rommel Rodriguez, additional

Published
2016
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12. Deregulated Expression of SRC, LYN and CKB Kinases by DNA Methylation and Its Potential Role in Gastric Cancer Invasiveness and Metastasis

Author

Mello, Adriano Azevedo, primary, Leal, Mariana Ferreira, additional, Rey, Juan Antonio, additional, Pinto, Giovanny Rebouças, additional, Lamarão, Leticia Martins, additional, Montenegro, Raquel Carvalho, additional, Alves, Ana Paula Negreiros Nunes, additional, Assumpção, Paulo Pimentel, additional, Borges, Barbara do Nascimento, additional, Smith, Marília Cardoso, additional, and Burbano, Rommel Rodriguez, additional

Published
2015
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13. Genetic screening analysis of patients with hereditary diffuse gastric cancer from northern and northeastern Brazil

Author

Moreira-Nunes, Caroline Aquino, primary, Barros, Mariceli Baia Leão, additional, do Nascimento Borges, Bárbara, additional, Montenegro, Raquel Carvalho, additional, Lamarão, Leticia Martins, additional, Ribeiro, Helem Ferreira, additional, Bona, Amanda Braga, additional, Assumpção, Paulo Pimentel, additional, Rey, Juan Antonio, additional, Pinto, Giovanny Rebouças, additional, and Burbano, Rommel Rodriguez, additional

Published
2014
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14. First isolation of enterovirus 71 (EV-71) from Northern Brazil

Author

Lamarão, Leticia Martins, Maciel, Ana Maria T. R., and Gomes, Maria de Lourdes Contente

Subjects
neurological disease, Enterovirus-71
Abstract

Enterovirus 71 (EV-71) has been associated to cases of neurological disease in many countries including Brazil. This virus has now been reported from three of the five Brazilian regions. Our study relates the findings concerning to the first isolate of this virus in Northern region of Brazil. A 15-month old female patient, from the rural zone of the municipality of Santana do Araguaia in southern Pará state was admitted at the hospital with acute, flaccid, asymmetric and ascending motor deficiency, located in the right lower limb. Stools samples from this child were inoculated in RD cells and was isolated an EV-71. We plan to sequence our strain and compare it to other isolates in Brazil. Differences at the molecular level can explain why EV-71 strains circulating in other continents, such as Asia, appear to be more virulent.

Published
2003

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