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1. Outcomes for Patients with Obesity Undergoing Adrenalectomy for Pheochromocytoma: An International Multicenter Analysis

Author

Verhoeff, Kevin, Parente, Alessandro, Wang, Yanbo, Wang, Nanya, Wang, Zhicheng, Śledziński, Maciej, Hellmann, Andrzej, Raffaelli, Marco, Pennestrì, Francesco, Sywak, Mark, Papachristos, Alexander J., Palazzo, Fausto F., Sung, Tae-Yon, Kim, Byung-Chang, Lee, Yu-mi, Eatock, Fiona, Anderson, Hannah, Iacobone, Maurizio, Daukša, Albertas, Makay, Ozer, Turk, Yigit, Atalay, Hafize Basut, van Dijkum, Els J. M. Nieveen, Engelsman, Anton F., Holscher, Isabelle, Materazzi, Gabriele, Rossi, Leonardo, Becucci, Chiara, Shore, Susannah L., Fung, Clare, Waghorn, Alison, Mihai, Radu, Balasubramanian, Sabapathy P., Pannu, Arslan, Tatarano, Shuichi, Velázquez-Fernández, David, Miller, Julie A., Serrao-Brown, Hazel, Chen, Yufei, Demarchi, Marco Stefano, Djafarrian, Reza, Doran, Helen, Wang, Kelvin, Stechman, Michael J., Perry, Helen, Hubbard, Johnathan, Lamas, Cristina, Mercer, Philippa, MacPherson, Janet, Lumbiganon, Supanut, Calatayud, María, Hanzu, Felicia Alexandra, Vidal, Oscar, Araujo-Castro, Marta, Ojeda, Cesar Minguez, Papavramidis, Theodosios, de Vera Gómez, Pablo Rodríguez, Aldrees, Abdulaziz, Altwjry, Tariq, Valdés, Nuria, Álvarez-Escola, Cristina, García Sanz, Iñigo, Blanco Carrera, Concepción, Manjón-Miguélez, Laura, De Miguel Novoa, Paz, Recasens, Mónica, García Centeno, Rogelio, Robles Lázaro, Cristina, Van Den Heede, Klaas, Van Slycke, Sam, Michalopoulou, Theodora, Aspinall, Sebastian, Melvin, Ross, Lau, Joel Wen Liang, Cheah, Wei Keat, Tang, Man Hon, Oh, Han Boon, Ayuk, John, and Sutcliffe, Robert P.

Published
2024
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2. Glucose metabolism outcomes after pituitary surgery in patients with acromegaly

Author

Pascual-Corrales, Eider, Biagetti, Betina, Marazuela, Mónica, Asensio-Wandosel, Diego, Rodríguez Berrocal, Víctor, Irigaray Echarri, Ana, Novo-Rodríguez, Cristina, Calatayud, María, Bernabéu, Ignacio, Alvarez-Escola, Cristina, Tenorio-Jiménez, Carmen, González Molero, Inmaculada, Iglesias, Pedro, Blanco, Concepción, de Miguel, Paz, López Mezquita, Elena, Lamas, Cristina, Aulinas, Anna, Gracia, Paola, Recio-Córdova, José María, Sampedro-Nuñez, Miguel, Paja, Miguel, Moure Rodríguez, María Dolores, Fajardo-Montañana, Carmen, Cordido, Fernando, Menéndez Torre, Edelmiro, Percovich, Juan Carlos, García-Centeno, Rogelio, Cámara, Rosa, Hanzu, Felicia Alexandra, Vicente Delgado, Almudena, González Fernández, Laura, Guerrero-Pérez, Fernando, Ollero García-Agulló, María Dolores, Novoa-Testa, Iría, Villar-Taibo, Rocío, Benítez Valderrama, Pamela, Abellán Galiana, Pablo, Venegas Moreno, Eva, Vidal-Ostos De Lara, Fernando, Enseñat, Joaquim, Aznar, Silvia, Asla, Queralt, Aviles-Pérez, María Dolores, Puig-Domingo, Manel, and Araujo-Castro, Marta

Published
2024
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3. Is adrenal venous sampling always necessary to differentiate between unilateral and bilateral primary aldosteronism? Lesson from the SPAIN-ALDO register

Author

Parra Ramírez, Paola, Martín Rojas-Marcos, Patricia, Paja Fano, Miguel, González Boillos, Marga, Peris, Begoña Pla, Pascual-Corrales, Eider, García Cano, Ana María, Ruiz-Sanchez, Jorge Gabriel, Vicente Delgado, Almudena, Gómez Hoyos, Emilia, Ferreira, Rui, García Sanz, Iñigo, Recasens Sala, Mònica, Barahona San Millan, Rebeca, Picón César, María José, Díaz Guardiola, Patricia, Perdomo, Carolina M., Manjón-Miguélez, Laura, García Centeno, Rogelio, Percovich, Juan Carlos, Rebollo Román, Ángel, Gracia Gimeno, Paola, Robles Lázaro, Cristina, Morales-Ruiz, Manuel, Calatayud, María, Furio Collao, Simone Andree, Meneses, Diego, Sampedro Nuñez, Miguel Antonio, Escudero Quesada, Verónica, Mena Ribas, Elena, Sanmartín Sánchez, Alicia, Gonzalvo Diaz, Cesar, Lamas, Cristina, Guerrero-Vázquez, Raquel, Del Castillo Tous, María, Serrano Gotarredona, Joaquín, Michalopoulou Alevras, Theodora, Moya Mateo, Eva María, Hanzu, Felicia A., and Araujo-Castro, Marta

Published
2024
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4. Renin as a Biomarker to Guide Medical Treatment in Primary Aldosteronism Patients. Findings from the SPAIN-ALDO Registry

Author

Parra Ramírez, Paola, Martín Rojas-Marcos, Patricia, Paja Fano, Miguel, González-Boillos, Margarita, Pascual-Corrales, Eider, García Cano, Ana María, Ruiz-Sanchez, Jorge Gabriel, Vicente Delgado, Almudena, Gómez Hoyos, Emilia, Ferreira, Rui, García Sanz, Iñigo, Recasens Sala, Mònica, Barahona San Millan, Rebeca, Picón César, María José, Díaz Guardiola, Patricia, Perdomo, Carolina M., Manjón-Miguélez, Laura, Rebollo Román, Ángel, Robles Lázaro, Cristina, Morales-Ruiz, Manuel, Calatayud, María, Andree Furio Collao, Simone, Meneses, Diego, Sampedro-Nuñez, Miguel Antonio, Mena Ribas, Elena, Sanmartín Sánchez, Alicia, Gonzalvo Diaz, Cesar, Lamas, Cristina, Guerrero-Vázquez, Raquel, del Castillo Tous, María, Serrano Gotarredona, Joaquín, Michalopoulou Alevras, Theodora, Tenés Rodrigo, Susana, Roa Chamorro, Ricardo, Jaen Aguila, Fernando, Moya Mateo, Eva María, Hanzu, Felicia A., and Araujo-Castro, Marta

Published
2024
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6. Acute Effect of Oral N-Acetylcysteine Supplementation on Fatigue Effect and Isometric Force Production in Physically Active People.

Author

Bravo-Sánchez, Alfredo, Portillo, Javier, Abián, Pablo, Ramírez-delaCruz, María, Lamas, Cristina, and Abián-Vicén, Javier

Abstract

The main objective of this study was to assess the ergogenic effect of N-acetylcysteine (NAC) on myotendinous isometric force production in physically active people after being subjected to a fatigue protocol. Twenty-three physically active people were randomly divided into the following two groups: NAC (n = 12; age = 26.8 ± 4.5 years, height = 173.1 ± 7.2 cm, and weight = 75.5 ± 7.5 kg), who received 2400 mg oral NAC, and control (n = 11; age = 23.4 ± 5.8 years, height = 175.9 ± 4.5 cm, and weight = 72.3 ± 9.9 kg), who received a placebo, for eight days. The isometric force production was assessed pre- and post-NAC supplementation during a maximal voluntary contraction test (MVC) and also during a fatigue protocol composed of seven sets of ten maximal isometric contraction repetitions of 5 s, with 5 s of rest between repetitions and 20 s between sets. No differences were observed between the groups in the force production values at any moment, and no side effects were found after NAC supplementation. After supplementation, a significant decrease in force was observed in both groups, but this significant loss of force started one set later in the NAC group compared to the control group (4th set vs. 5th set), which could be an ergogenic effect of the treatment. Therefore, oral daily supplementation with 2400 mg of NAC for eight days, could delay the decrease in force production during an isometric exercise protocol and without adverse side effects. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Impact of Cortisol-Cosecretion on Adrenal Venous Sampling Results in Primary Aldosteronism: Study of 225 Cases.

Author

Lamas, Cristina, Araujo-Castro, Marta, Ostermair, Lukas, Petersenn, Erik, Parra Ramírez, Paola, Rebollo-Román, Ángel, Stuefchen, Isabel, Bruedgam, Denise, Ruiz-Sanchez, Jorge Gabriel, Michalopoulou, Theodora, Perdomo, Carolina M., Hanzu, Felicia A., Adolf, Christian, and Reincke, Martin

Abstract

Background/Objectives: Mild autonomous cortisol secretion (MACS) can coexist with primary aldosteronism (PA). The purpose of our study was to evaluate whether (MACS) influences parameters analyzed during adrenal venous sampling (AVS) in patients with PA. Methods: Patients with PA from the SPAIN-ALDO Registry and the German Conn's Registry with available 1 mg-dexamethasone suppression test (DST) and AVS were included. MACS was defined as a post-DST cortisol > 1.8 µg/dL in the absence of specific signs and symptoms of Cushing's syndrome. Results: Two-hundred and twenty-five patients were included, 98 (43.6%) of whom had concomitant MACS. The mean age was 54 ± 10 years and 37.3% were women. AVS was performed by simultaneous catheterization of both adrenal veins and analysis of basal samples in 157 patients (69.8%), with both basal and post-ACTH samples in 15 patients (6.7%), and during continuous ACTH infusion in 53 patients (23.6%). AVS was considered technically unsuccessful in 40 cases (17.8%), suggesting unilateral secretion in 106 (47.1%) and bilateral secretion in 79 (35.1%). We did not find significant differences in the percentage of unilateral and bilateral results, cortisol, corrected aldosterone, or selectivity indices in the dominant and non-dominant veins, nor in the lateralization index or the contralateral suppression index between patients with and without MACS. They also had similar rates of surgical treatment and biochemical and clinical response. Conclusions: Although pathophysiological reasoning suggests that MACS could hinder AVS identification of unilateral forms of PA, our data suggest that such interference, if it exists, is of moderate clinical relevance. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Long term outcomes of pituitary adenomas in Multiple Endocrine Neoplasia type 1: a nationwide study.

Author

Valdés, Nuria, Romero, Ana, Diego, Estrella, Calatayud, María, Lamas, Cristina, Araujo-Castro, Marta, Álvarez-Escolá, Cristina, Díaz, José A., Alcázar, Victoria, Sastre, Julia, Martínez, Rosa, Oriola, Josep, Paja, Miguel, Sánchez-Sobrino, Paula, Salinas, Isabel, María Recio-Córdova, José, Navarro, Elena, Chiara, María Dolores, Castaño, Luis, and Casterás, Anna

Subjects
PITUITARY tumors, DOPAMINE agonists, TREATMENT duration, GERM cells, TUMORS
Abstract

Introduction: Historically, Multiple Endocrine Neoplasia type 1 (MEN1)-related pituitary adenomas (PAs) were considered more aggressive and treatmentresistant than sporadic PAs. However, recent studies suggest similarities in their behavior. This study aimed to evaluate the long-term outcomes of MEN1 PAs and identify predictive factors. Methods: Nationwide multicenter retrospective cohort study of MEN1-related PAs with a minimum 1-year follow-up, collecting patient demographics, germline MEN1 pathogenic variants (PV), PA size, secretory profile, radiological characteristics, treatments, and outcomes. Results: We analyzed 84 PAs, 69%in females and 31% in males (P<0.001), diagnosed at a mean age of 35.2±14.9 years, mostly through screening (60.7%). Median follow-up was 9 years (IQR:4-16). Prolactin-secreting PAs (PRLomas) (53.5%) and microadenomas (65.5%) were most common. Dopamine agonist treatment was first line for 16 macroPRLomas and 25 microPRLomas, 60.9% of them achieved PRL normalization. There was no significant association observed with tumor size, sex, treatment duration or MEN1 PV. The risk of progression from micro-PA to invasive macro-PA was 7.2% (4/55), after 8 years (IQR:4-13), all of them were microPRLomas. Kaplan-Meier estimation curve showed significantly higher progression probability in microPRLomas than in other microadenomas subtypes (P=0.017) or microNFPAs (P=0.032). No differences were found between sex, age, or germline MEN1 PV. Conclusion: MEN1-related micro-PAs have a low risk of progressing to invasive macro-PAs, regardless of sex, age at diagnosis, or MEN1 germline PV. The risk is higher for microPRLomas over the long term. Therefore, long-term surveillance with reduced frequency, rather than intensive short-term monitoring, may be appropriate for patients with MEN1-related PAs. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Predictive model of pheochromocytoma based on the imaging features of the adrenal tumours

Author

Araujo-Castro, Marta, García Centeno, Rogelio, Robles Lázaro, Cristina, Parra Ramírez, Paola, Gracia Gimeno, Paola, Rojas-Marcos, Patricia Martín, Fernández-Ladreda, Mariana Tomé, Percovich Hualpa, Juan Carlos, Sampedro Núñez, Miguel, López-García, María-Carmen, Lamas, Cristina, Álvarez Escolá, Cristina, Calatayud Gutiérrez, María, Blanco Carrera, Concepción, de Miguel Novoa, Paz, Valdés Gallego, Nuria, Hanzu, Felicia, Marazuela, Mónica, Mora Porta, Mireia, Mínguez Ojeda, César, García Gómez Muriel, Isabel, Escobar-Morreale, Héctor F., and Valderrabano, Pablo

Published
2022
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10. Data mining analyses for precision medicine in acromegaly: a proof of concept

Author

Gil, Joan, Marques-Pamies, Montserrat, Sampedro, Miguel, Webb, Susan M., Serra, Guillermo, Salinas, Isabel, Blanco, Alberto, Valassi, Elena, Carrato, Cristina, Picó, Antonio, García-Martínez, Araceli, Martel-Duguech, Luciana, Sardon, Teresa, Simó-Servat, Andreu, Biagetti, Betina, Villabona, Carles, Cámara, Rosa, Fajardo-Montañana, Carmen, Álvarez-Escolá, Cristina, Lamas, Cristina, Alvarez, Clara V., Bernabéu, Ignacio, Marazuela, Mónica, Jordà, Mireia, and Puig-Domingo, Manel

Published
2022
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11. Effectiveness of Combined First-Line Medical Treatment in Acromegaly with Prolactin Co-secretion

Author

Biagetti, Betina, primary, Araujo-Castro, Marta, additional, Menéndez Torre, Edelmiro, additional, Novoa-Testa, Iría, additional, Cordido, Fernando, additional, Pascual Corrales, Eider, additional, Rodríguez Berrocal, Víctor, additional, Guerrero-Pérez, Fernando, additional, Vicente, Almudena, additional, Percovich, Juan Carlos, additional, García Centeno, Rogelio, additional, González, Laura, additional, Ollero García, María Dolores, additional, Irigaray Echarri, Ana, additional, Moure Rodríguez, María Dolores, additional, Novo-Rodríguez, Cristina, additional, Calatayud, María, additional, Villar-Taibo, Rocío, additional, Bernabéu, Ignacio, additional, Alvarez-Escola, Cristina, additional, Benítez Valderrama, Pamela, additional, Tenorio, Carmen, additional, Abellán Galiana, Pablo, additional, Venegas Moreno, Eva, additional, González Molero, Inmaculada, additional, Iglesias, Pedro, additional, Blanco, Concepción, additional, Vidal-Ostos De Lara, Fernando, additional, de Miguel, Paz, additional, López Mezquita, Elena, additional, Hanzu, Felicia, additional, Aldecoa, Iban, additional, Aznar, Silvia, additional, Lamas, Cristina, additional, Aulinas, Anna, additional, Asla, Queralt, additional, Gracia, Paola, additional, Recio Córdova, José María, additional, Aviles, Mariola, additional, Asensio-Wandosel, Diego, additional, Sampedro, Miguel, additional, Cámara, Rosa, additional, Paja, Miguel, additional, Ruz-Caracuel, Ignacio, additional, Fajardo-Montañana, Carmen, additional, Cordero Asanza, Esteban, additional, Martinez-Saez, Elena, additional, Marazuela, Mónica, additional, and Puig-Domingo, Manel, additional

Published
2024
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12. Glucose metabolism outcomes after pituitary surgery in patients with acromegaly

Author

Pascual-Corrales, Eider, primary, Biagetti, Betina, additional, Marazuela, Mónica, additional, Asensio-Wandosel, Diego, additional, Berrocal, Víctor Rodríguez, additional, Echarri, Ana Irigaray, additional, Novo-Rodríguez, Cristina, additional, Calatayud, María, additional, Bernabéu, Ignacio, additional, Alvarez-Escola, Cristina, additional, Tenorio-Jiménez, Carmen, additional, Molero, Inmaculada González, additional, Iglesias, Pedro, additional, Blanco, Concepción, additional, Miguel, Paz, additional, Mezquita, Elena López, additional, Lamas, Cristina, additional, Aulinas, Anna, additional, Gracia, Paola, additional, Recio-Córdova, José María, additional, Sampedro-Nuñez, Miguel, additional, Paja, Miguel, additional, Rodríguez, María Dolores Moure, additional, Fajardo-Montañana, Carmen, additional, Cordido, Fernando, additional, Torre, Edelmiro Menéndez, additional, Percovich, Juan Carlos, additional, García-Centeno, Rogelio, additional, Cámara, Rosa, additional, Hanzu, Felicia Alexandra, additional, Delgado, Almudena Vicente, additional, Fernández, Laura González, additional, Guerrero-Pérez, Fernando, additional, García-Agulló, María Dolores Ollero, additional, Novoa-Testa, Iría, additional, Villar-Taibo, Rocío, additional, Valderrama, Pamela Benítez, additional, Galiana, Pablo Abellán, additional, Moreno, Eva Venegas, additional, De Lara, Fernando Vidal-Ostos, additional, Enseñat, Joaquim, additional, Aznar, Silvia, additional, Asla, Queralt, additional, Aviles, Mariola, additional, Puig-Domingo, Manel, additional, and Araujo-Castro, Marta, additional

Published
2024
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14. Pegvisomant or pasirotide in PRL and GH co-secreting vs GH-secreting Pit-NETs

Author

Araujo-Castro, Marta, primary, Biagetti, Betina, additional, Menedez-Torre, Edelmiro, additional, Novoa-Testa, Iría, additional, Cordido, Fernando, additional, Pascual-Corrales, Eider, additional, Rodríguez Berrocal, Víctor, additional, Guerrero-Pérez, Fernando, additional, Vicente, Almudena, additional, Percovich Hualpa, Juan Carlos, additional, Garcia Centeno, Rogelio, additional, González Fernández, Laura, additional, Ollero García, María Dolores, additional, Irigaray Echarri, Ana, additional, Moure Rodríguez, María Dolores, additional, Novo-Rodríguez, Cristina, additional, Calatayud, María, additional, Villar, Rocío, additional, Bernabéu, Ignacio, additional, Alvarez-Escola, Cristina, additional, Benítez Valderrama, Pamela, additional, Tenorio, Carmen, additional, Abellán Galiana, Pablo, additional, Venegas, Eva, additional, González-Molero, Inmaculada, additional, Iglesias, Pedro, additional, Blanco-Carrera, Concepción, additional, Vidal-Ostos De Lara, Fernando, additional, de Miguel Novoa, Paz, additional, López Mezquita, Elena, additional, Hanzu, Felicia Alexandra, additional, Aldecoa, Iban, additional, Aznar, Silvia, additional, Lamas, Cristina, additional, Aulinas, Anna, additional, Queralt Asla, Anna, additional, Gracia Gimeno, Paola, additional, Recio Córdova, José María, additional, Aviles, Mariola, additional, Asensio-Wandosel, Diego, additional, Sampedro-Núñez, Miguel, additional, Camara, Rosa, additional, Paja Fano, Miguel, additional, Ruz-Caracuel, Ignacio, additional, Fajardo, Carmen, additional, Marazuela, Mónica, additional, and Puig-Domingo, Manel, additional

Published
2024
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16. Differences Between GH- and PRL-Cosecreting and GH-Secreting Pituitary Adenomas: a Series of 604 Cases

Author

Araujo-Castro, Marta, primary, Biagetti, Betina, additional, Menéndez Torre, Edelmiro, additional, Novoa-Testa, Iría, additional, Cordido, Fernando, additional, Pascual Corrales, Eider, additional, Rodríguez Berrocal, Víctor, additional, Guerrero-Pérez, Fernando, additional, Vicente, Almudena, additional, Percovich, Juan Carlos, additional, García Centeno, Rogelio, additional, González, Laura, additional, Ollero García, María Dolores, additional, Irigaray Echarri, Ana, additional, Moure Rodríguez, María Dolores, additional, Novo-Rodríguez, Cristina, additional, Calatayud, María, additional, Villar, Rocío, additional, Bernabéu, Ignacio, additional, Alvarez-Escola, Cristina, additional, Benítez Valderrama, Pamela, additional, Tenorio-Jimenéz, Carmen, additional, Abellán Galiana, Pablo, additional, Venegas Moreno, Eva, additional, González Molero, Inmaculada, additional, Iglesias, Pedro, additional, Blanco, Concepción, additional, Vidal-Ostos De Lara, Fernando, additional, de Miguel, Paz, additional, López Mezquita, Elena, additional, Hanzu, Felicia, additional, Aldecoa, Iban, additional, Lamas, Cristina, additional, Aznar, Silvia, additional, Aulinas, Anna, additional, Calabrese, Anna, additional, Gracia, Paola, additional, Recio-Córdova, José María, additional, Aviles, Mariola, additional, Asensio-Wandosel, Diego, additional, Sampedro, Miguel, additional, Ruz-Caracuel, Ignacio, additional, Camara, Rosa, additional, Paja, Miguel, additional, Fajardo-Montañana, Carmen, additional, Marazuela, Mónica, additional, and Puig-Domingo, Manel, additional

Published
2024
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17. Differences in the clinical and hormonal presentation of patients with familial and sporadic primary aldosteronism

Author

Araujo-Castro, Marta, primary, Parra, Paola, additional, Martín Rojas-Marcos, Patricia, additional, Paja Fano, Miguel, additional, González Boillos, Marga, additional, Pascual-Corrales, Eider, additional, García Cano, Ana María, additional, Ruiz-Sanchez, Jorge Gabriel, additional, Vicente Delgado, Almudena, additional, Gómez Hoyos, Emilia, additional, Ferreira, Rui, additional, García Sanz, Iñigo, additional, Recasens Sala, Mònica, additional, Barahona San Millan, Rebeca, additional, Picón César, María José, additional, Díaz Guardiola, Patricia, additional, Perdomo, Carolina M., additional, Manjón-Miguélez, Laura, additional, García Centeno, Rogelio, additional, Rebollo Román, Ángel, additional, Gracia Gimeno, Paola, additional, Robles Lázaro, Cristina, additional, Morales-Ruiz, Manuel, additional, Calatayud, María, additional, Furio Collao, Simone Andree, additional, Meneses, Diego, additional, Sampedro Nuñez, Miguel, additional, Escudero Quesada, Verónica, additional, Mena Ribas, Elena, additional, Sanmartín Sánchez, Alicia, additional, Gonzalvo Diaz, Cesar, additional, Lamas, Cristina, additional, del Castillo Tous, María, additional, Serrano Gotarredona, Joaquín, additional, Michalopoulou Alevras, Theodora, additional, Moya Mateo, Eva María, additional, and Hanzu, Felicia A., additional

Published
2024
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20. Local recurrence and metastatic disease in pheochromocytomas and sympathetic paragangliomas

Author

Araujo-Castro, Marta, primary, García Sanz, Iñigo, additional, Mínguez Ojeda, César, additional, Hanzu, Felicia, additional, Mora, Mireia, additional, Vicente, Almudena, additional, Blanco Carrera, Concepción, additional, de Miguel Novoa, Paz, additional, López García, María del Carmen, additional, Lamas, Cristina, additional, Manjón-Miguélez, Laura, additional, del Castillo Tous, María, additional, Rodríguez de Vera, Pablo, additional, Barahona San Millán, Rebeca, additional, Recasens, Mónica, additional, Tomé Fernández-Ladreda, Mariana, additional, Valdés, Nuria, additional, Gracia Gimeno, Paola, additional, Robles Lazaro, Cristina, additional, Michalopoulou, Theodora, additional, Álvarez Escolá, Cristina, additional, García Centeno, Rogelio, additional, Barca-Tierno, Verónica, additional, Herrera-Martínez, Aura D., additional, and Calatayud, María, additional

Published
2023
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21. Is adrenal venous sampling always necessary to differentiate between unilateral and bilateral primary aldosteronism? Lesson from the SPAIN-ALDO register

Author

Parra Ramírez, Paola, primary, Martín Rojas-Marcos, Patricia, additional, Paja Fano, Miguel, additional, González Boillos, Marga, additional, Peris, Begoña Pla, additional, Pascual-Corrales, Eider, additional, García Cano, Ana María, additional, Ruiz-Sanchez, Jorge Gabriel, additional, Vicente Delgado, Almudena, additional, Gómez Hoyos, Emilia, additional, Ferreira, Rui, additional, García Sanz, Iñigo, additional, Recasens Sala, Mònica, additional, Barahona San Millan, Rebeca, additional, Picón César, María José, additional, Díaz Guardiola, Patricia, additional, Perdomo, Carolina M., additional, Manjón-Miguélez, Laura, additional, García Centeno, Rogelio, additional, Percovich, Juan Carlos, additional, Rebollo Román, Ángel, additional, Gracia Gimeno, Paola, additional, Robles Lázaro, Cristina, additional, Morales-Ruiz, Manuel, additional, Calatayud, María, additional, Furio Collao, Simone Andree, additional, Meneses, Diego, additional, Sampedro Nuñez, Miguel Antonio, additional, Escudero Quesada, Verónica, additional, Mena Ribas, Elena, additional, Sanmartín Sánchez, Alicia, additional, Gonzalvo Diaz, Cesar, additional, Lamas, Cristina, additional, Guerrero-Vázquez, Raquel, additional, Del Castillo Tous, María, additional, Serrano Gotarredona, Joaquín, additional, Michalopoulou Alevras, Theodora, additional, Moya Mateo, Eva María, additional, Hanzu, Felicia A., additional, and Araujo-Castro, Marta, additional

Published
2023
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23. Therapeutic Management and Long-Term Outcome of Hy-Perthyroidism in Patients with Antithyroid-Induced Agranu-Locytosis: A Retrospective, Multicenter Study

Author

García Gómez, Carlos, primary, Navarro, Elena, additional, Alcázar, Victoria, additional, López-Guzmán, Antonio, additional, Arrieta, Francisco, additional, Anda, Emma, additional, Biagetti, Betina, additional, Guerrero-Pérez, Fernando, additional, Villabona, Carles, additional, Ruiz de Assín Valverde, Andrés, additional, Lamas, Cristina, additional, Lecumberri, Beatriz, additional, Rosado Sierra, José Antonio, additional, Sastre, Julia, additional, Díez, Juan José, additional, and Iglesias, Pedro, additional

Published
2023
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24. Risk factors for intraoperative hypertensive crisis in patients with pheochromocytomas and sympathetic paragangliomas

Author

Araujo-Castro, Marta, primary, García Sanz, Iñigo, additional, Mínguez Ojeda, César, additional, Hanzu, Felicia, additional, Mora, Mireia, additional, Vicente, Almudena, additional, Blanco Carrera, Concepción, additional, Miguel Novoa, Paz de, additional, López García, María del Carmen, additional, Lamas, Cristina, additional, Manjón-Miguélez, Laura, additional, del Castillo Tous, María, additional, Rodríguez de Vera, Pablo, additional, Barahona San Millán, Rebeca, additional, Recasens, Mónica, additional, Fernández-Ladreda, Mariana Tomé, additional, Valdés, Nuria, additional, Gracia Gimeno, Paola, additional, Robles Lazaro, Cristina, additional, Michalopoulou, Theodora, additional, Álvarez Escolá, Cristina, additional, García Centeno, Rogelio, additional, and Calatayud, María, additional

Published
2023
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25. FRI145 Prevalence Of Type 2 Diabetes Mellitus And Risk Factors For Its Development In Patients With Primary Aldosteronism

Author

Araujo-Castro, Marta, primary, Paja Fano, Miguel, additional, González Boillos, Marga, additional, Pla Peris, Begoña, additional, Pascual-Corrales, Eider, additional, García Cano, Ana María, additional, Parra, Paola, additional, Martín Rojas-Marcos, Patricia, additional, Ruiz-Sanchez, Jorge Gabriel, additional, Vicente Delgado, Almudena, additional, Gómez Hoyos, Emilia, additional, Ferreira, Rui, additional, García Sanz, Iñigo, additional, Recasens Sala, Mònica, additional, San Millan, Rebeca Barahona, additional, Picón César, María José, additional, Díaz Guardiola, Patricia, additional, García González, Juan Jesús, additional, Perdomo, Carolina M, additional, Manjón Miguélez, Laura, additional, García Centeno, Rogelio, additional, Rebollo Román, Ángel, additional, Gracia Gimeno, Paola, additional, Robles Lázaro, Cristina, additional, Morales-Ruiz, Manuel, additional, Calatayud Gutiérrez, María, additional, Andree Furio Collao, Simone Simone, additional, Meneses, Diego, additional, Sampedro Nuñez, Miguel Antonio, additional, Escudero Quesada, Verónica, additional, Mena Ribas, Elena, additional, Sanmartin Sánchez, Alicia, additional, Gonzalvo Diaz, Cesar, additional, Lamas, Cristina, additional, and Hanzu, Felicia, additional

Published
2023
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28. Efficacy and safety of temozolomide in the treatment of aggressive pituitary neuroendocrine tumours in Spain

Author

Lamas, Cristina, primary, Cámara, Rosa, additional, Fajardo, Carmen, additional, Remon-Ruiz, Pablo, additional, Biagetti, Betina, additional, Guerrero-Pérez, Fernando, additional, Araujo-Castro, Marta, additional, Mora, Mireia, additional, Hanzu, Felicia, additional, Iglesias, Pedro, additional, García-Centeno, Rogelio, additional, and Soto, Alfonso, additional

Published
2023
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29. An Integrated CT and MRI Imaging Model to Differentiate between Adrenal Adenomas and Pheochromocytomas

Author

Araujo-Castro, Marta, primary, García Sanz, Iñigo, additional, Mínguez Ojeda, César, additional, Calatayud, María, additional, Hanzu, Felicia A., additional, Mora, Mireia, additional, Vicente Delgado, Almudena, additional, Carrera, Concepción Blanco, additional, de Miguel Novoa, Paz, additional, del Carmen López García, María, additional, Manjón-Miguélez, Laura, additional, Rodríguez de Vera Gómez, Pablo, additional, del Castillo Tous, María, additional, Barahona San Millán, Rebeca, additional, Recansens, Mónica, additional, Fernández-Ladreda, Mariana Tomé, additional, Valdés, Nuria, additional, Gracia Gimeno, Paola, additional, Robles Lazaro, Cristina, additional, Michalopoulou, Theodora, additional, Gómez Dos Santos, Victoria, additional, Alvarez-Escola, Cristina, additional, García Centeno, Rogelio, additional, Lamas, Cristina, additional, and Herrera-Martínez, Aura, additional

Published
2023
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30. Autonomous cortisol secretion in patients with primary aldosteronism: prevalence and implications on cardiometabolic profile and on surgical outcomes

Author

Araujo-Castro, Marta, primary, Paja Fano, Miguel, additional, Pla Peris, Begoña, additional, González Boillos, Marga, additional, Pascual-Corrales, Eider, additional, García-Cano, Ana María, additional, Parra Ramírez, Paola, additional, Rojas-Marcos, Patricia Martín, additional, Ruiz-Sanchez, Jorge Gabriel, additional, Vicente, Almudena, additional, Gómez-Hoyos, Emilia, additional, Ferreira, Rui, additional, García Sanz, Iñigo, additional, Recasens, Mónica, additional, Barahona San Millan, Rebeca, additional, Picón César, María José, additional, Díaz Guardiola, Patricia, additional, Perdomo, Carolina, additional, Manjón, Laura, additional, García-Centeno, Rogelio, additional, Percovich, Juan Carlos, additional, Rebollo Román, Ángel, additional, Gracia Gimeno, Paola, additional, Robles Lázaro, Cristina, additional, Morales, Manuel, additional, Calatayud, María, additional, Collao, Simone Andree Furio, additional, Meneses, Diego, additional, Sampedro Nuñez, Miguel Antonio, additional, Escudero Quesada, Verónica, additional, Ribas, Elena Mena, additional, Sanmartín Sánchez, Alicia, additional, Diaz, Cesar Gonzalvo, additional, Lamas, Cristina, additional, Guerrero-Vázquez, Raquel, additional, del Castillo Tous, María, additional, Serrano, Joaquín, additional, Michalopoulou, Theodora, additional, Moya Mateo, Eva María, additional, and Hanzu, Felicia, additional

Published
2023
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31. Prevalence of autonomous cortisol secretion in patients with primary aldosteronism and its implications on the cardiometabolic profile and on surgical outcomes

Author

Araujo, Castro Marta, primary, Paja, Fano Miguel, additional, Pla, Peris Begona, additional, Gonzalez, Boillos Margarita, additional, Pascual-Corrales, Eider, additional, Garcia, Cano Ana, additional, Parra, Ramirez Paola, additional, Martin, Rojas Patricia, additional, Gabriel, Ruiz Sanchez Jorge, additional, Vicente, Almudena, additional, Gomez, Hoyos Emilia, additional, Garcia, Sanz Inigo, additional, Barahona, San Millan Rebeca, additional, Jose, Picon Cesar Maria, additional, Diaz, Guardiola Patricia, additional, M., Perdomo Carolina, additional, Manjon, Miguelez Laura, additional, Rebollo-Roman, Angel, additional, Calatayud, Maria, additional, Lamas, Cristina, additional, Michalopoulou, Alevras Theodora, additional, C., Tous Romero Maria, additional, Garcia, Centeno Rogelio, additional, Robles, Lazaro Cristina, additional, Gracia, Gimeno Paola, additional, Antonio, Sampedro Nunez Miguel, additional, Mena, Ribas Elena, additional, Sanmartin, Sanchez Alicia, additional, Serrano, Joaquin, additional, Maria, Moya Mateo Eva, additional, Escudero, Quesada Veronica, additional, and Alexandra, Hanzu Felicia, additional

Published
2023
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34. Therapeutic Management and Long-Term Outcome of Hyperthyroidism in Patients with Antithyroid-Induced Agranulocytosis: A Retrospective, Multicenter Study.

Author

García Gómez, Carlos, Navarro, Elena, Alcázar, Victoria, López-Guzmán, Antonio, Arrieta, Francisco, Anda, Emma, Biagetti, Betina, Guerrero-Pérez, Fernando, Villabona, Carles, de Assín Valverde, Andrés Ruiz, Lamas, Cristina, Lecumberri, Beatriz, Rosado Sierra, José Antonio, Sastre, Julia, Díez, Juan José, and Iglesias, Pedro

Subjects
AGRANULOCYTOSIS, SEPTIC shock, THYROIDECTOMY, HOSPITAL admission & discharge, THERAPEUTIC complications, IODINE isotopes, THYROID hormones
Abstract

Background: Antithyroid drug-induced agranulocytosis (AIA) (neutrophils <500/µL) is a rare but serious complication in the treatment of hyperthyroidism. Methodology: Adult patients with AIA who were followed up at 12 hospitals in Spain were retrospectively studied. A total of 29 patients were studied. The etiology of hyperthyroidism was distributed as follows: Graves' disease (n = 21), amiodarone-induced thyrotoxicosis (n = 7), and hyperfunctioning multinodular goiter (n = 1). Twenty-one patients were treated with methimazole, as well as six patients with carbimazole and two patients with propylthiouracil. Results: The median (IQR) time to development of agranulocytosis was 6.0 (4.0–11.5) weeks. The most common presenting sign was fever accompanied by odynophagia. All of the patients required admission, reverse isolation, and broad-spectrum antibiotics; moreover, G-CSF was administered to 26 patients (89.7%). Twenty-one patients received definitive treatment, thirteen patients received surgery, nine patients received radioiodine, and one of the patients required both treatments. Spontaneous normalization of thyroid hormone values occurred in six patients (four patients with amiodarone-induced thyrotoxicosis and two patients with Graves' disease), and two patients died of septic shock secondary to AIA. Conclusions: AIA is a potentially lethal complication that usually appears around 6 weeks after the initiation of antithyroid therapy. Multiple drugs are required to control hyperthyroidism before definitive treatment; additionally, in a significant percentage of patients (mainly in those treated with amiodarone), hyperthyroidism resolved spontaneously. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Genetic study in pheochromocytoma ¿is it possible to stratify the risk of hereditary pheochromocytoma?

Author

Araujo-Castro, Marta, primary, Mínguez Ojeda, César, additional, García Sanz, Iñigo, additional, Calatayud, Maria, additional, Hanzu, Felicia, additional, Mora, Mireia, additional, Vicente, Almudena, additional, Blanco Carrera, CONCEPCION, additional, De Miguel Novoa, Paz, additional, López García, María Del Carmen, additional, Lamas, Cristina, additional, Manjón-Miguélez, Laura, additional, del Castillo Tous, María, additional, Rodríguez de Vera, Pablo, additional, Barahona San Millán, Rebeca, additional, Recasens, Mónica, additional, Tomé Fernández-Ladreda, Mariana, additional, Valdés, Nuria, additional, Gracia Gimeno, Paola, additional, Robles Lazaro, Cristina, additional, Michalopoulou, Theodora, additional, Parra Ramírez, Paola, additional, Marazuela, Mónica, additional, Álvarez Escolá, Cristina, additional, and García Centeno, Rogelio, additional

Published
2023
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37. Oseltamivir-induced toxic epidermal necrolysis in a patient with Cushing's disease

Author

González-Ramos, JéSsica, Lamas, Cristina, Bellón, Teresa, Ruiz-Bravo, Elena, Ramírez, Elena, Lerma, Victoria, and Lecumberri, Beatriz

Subjects
Oseltamivir phosphate -- Complications and side effects, Methicillin -- Complications and side effects, Meropenem -- Complications and side effects, Health
Abstract

Byline: Jéssica. González-Ramos, Cristina. Lamas, Teresa. Bellón, Elena. Ruiz-Bravo, Elena. Ramírez, Victoria. Lerma, Beatriz. Lecumberri We report a case of a patient with Cushing's disease with oseltamivir-induced toxic epidermal necrolysis, [...]

Published
2020

38. Glycemic disorders in patients with pheochromocytomas and sympathetic paragangliomas

Author

Araujo-Castro, Marta, primary, Mínguez Ojeda, César, additional, García Centeno, Rogelio, additional, López-García, María-Carmen, additional, Lamas, Cristina, additional, Hanzu, Felicia Alexandra, additional, Mora, Mireia, additional, del Castillo Tous, María, additional, Rodríguez de Vera Gómez, Pablo, additional, Parra Ramírez, Paola, additional, Alvarez-Escola, Cristina, additional, Blanco Carrera, Concepción, additional, Barahona San Millán, Rebeca, additional, Recasens, Mónica, additional, Valdés, Nuria, additional, Gracia Gimeno, Paola, additional, de Miguel Novoa, Paz, additional, Vicente, Almudena, additional, Manjón, Laura, additional, García Sanz, Iñigo, additional, Michalopoulou, Theodora, additional, and Calatayud, María, additional

Published
2022
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39. Implications of Heterogeneity of Epithelial-Mesenchymal States in Acromegaly Therapeutic Pharmacologic Response

Author

Gil, Joan, Marques-Pamies, Montserrat, Valassi, Elena, García-Martínez, Araceli, Serra, Guillermo, Hostalot, Cristina, Fajardo-Montañana, Carmen, Carrato, Cristina, Bernabeu, Ignacio, Marazuela, Mónica, Rodríguez-Lloveras, Helena, Cámara, Rosa, Salinas, Isabel, Lamas, Cristina, Biagetti, Betina, Simó-Servat, Andreu, Webb, S. M, Picó, Antonio, Jordà, Mireia, Puig Domingo, Manuel, Gil, Joan, Marques-Pamies, Montserrat, Valassi, Elena, García-Martínez, Araceli, Serra, Guillermo, Hostalot, Cristina, Fajardo-Montañana, Carmen, Carrato, Cristina, Bernabeu, Ignacio, Marazuela, Mónica, Rodríguez-Lloveras, Helena, Cámara, Rosa, Salinas, Isabel, Lamas, Cristina, Biagetti, Betina, Simó-Servat, Andreu, Webb, S. M, Picó, Antonio, Jordà, Mireia, and Puig Domingo, Manuel

Abstract

Acromegaly is caused by excess growth hormone (GH) produced by a pituitary tumor. First-generation somatostatin receptor ligands (SRLs) are the first-line treatment. Several studies have linked E-cadherin loss and epithelial-mesenchymal transition (EMT) with resistance to SRLs. Our aim was to study EMT and its relationship with SRLs resistance in GH-producing tumors. We analyzed the expression of EMT-related genes by RT-qPCR in 57 tumors. The postsurgical response to SRLs was categorized as complete response, partial response, or nonresponse if IGF-1 was normal, had decreased more than 30% without normalization, or neither of those, respectively. Most tumors showed a hybrid and variable EMT expression profile not specifically associated with SRL response instead of a defined epithelial or mesenchymal phenotype. However, high SNAI1 expression was related to invasive and SRL-nonresponsive tumors. RORC was overexpressed in tumors treated with SRLs before surgery, and this increased expression was more prominent in those cases that normalized postsurgical IGF-1 levels under SRL treatment. In conclusion, GH-producing tumors showed a heterogeneous expression pattern of EMT-related genes that would partly explain the heterogeneous response to SRLs. SNAI1 and RORC may be useful to predict response to SRLs and help medical treatment decision making.

Published
2022

40. Integrative Clinical, Radiological, and Molecular Analysis for Predicting Remission and Recurrence of Cushing Disease

Author

Junta de Andalucía, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Instituto de Salud Carlos III, European Commission, Ministerio de Educación, Cultura y Deporte (España), Grupo Español de Tumores Neuroendocrinos y Endocrinos, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Herrera-Martínez, Aura D. [0000-0003-1437-9878], Castaño, Justo P. [0000-0002-3145-7287], Luque, Raúl M. [0000-0002-7585-1913], Moreno-Moreno, Paloma, Ibáñez-Costa, Alejandro, Venegas Moreno, Eva, Fuentes-Fayos, Antonio C., Alhambra-Expósito, María R., Fajardo-Montañana, Carmen, García-Martínez, Araceli, Dios Fuentes, Elena, Vázquez-Borrego, Mari C., Remón-Ruiz, Pablo, Cámara, Rosa, Lamas, Cristina, Padillo-Cuenca, José Carlos, Solivera, Juan, Cano González, David A., Gahete, Manuel D., Herrera-Martínez, Aura D., Picó-Alfonso, Antonio Miguel, Soto-Moreno, Alfonso, Gálvez-Moreno, María Ángeles, Castaño, Justo P., Luque, Raúl M., Junta de Andalucía, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Instituto de Salud Carlos III, European Commission, Ministerio de Educación, Cultura y Deporte (España), Grupo Español de Tumores Neuroendocrinos y Endocrinos, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Herrera-Martínez, Aura D. [0000-0003-1437-9878], Castaño, Justo P. [0000-0002-3145-7287], Luque, Raúl M. [0000-0002-7585-1913], Moreno-Moreno, Paloma, Ibáñez-Costa, Alejandro, Venegas Moreno, Eva, Fuentes-Fayos, Antonio C., Alhambra-Expósito, María R., Fajardo-Montañana, Carmen, García-Martínez, Araceli, Dios Fuentes, Elena, Vázquez-Borrego, Mari C., Remón-Ruiz, Pablo, Cámara, Rosa, Lamas, Cristina, Padillo-Cuenca, José Carlos, Solivera, Juan, Cano González, David A., Gahete, Manuel D., Herrera-Martínez, Aura D., Picó-Alfonso, Antonio Miguel, Soto-Moreno, Alfonso, Gálvez-Moreno, María Ángeles, Castaño, Justo P., and Luque, Raúl M.

Abstract

[Context] Adrenocorticotropin (ACTH)-secreting pituitary tumors (ACTHomas) are associated with severe comorbidities and increased mortality. Current treatments mainly focus on remission and prevention of persistent disease and recurrence. However, there are still no useful biomarkers to accurately predict the clinical outcome after surgery, long-term remission, or disease relapse., [Objectives] This work aimed to identify clinical, biochemical, and molecular markers for predicting long-term clinical outcome and remission in ACTHomas., [Methods] A retrospective multicenter study was performed with 60 ACTHomas patients diagnosed between 2004 and 2018 with at least 2 years’ follow-up. Clinical/biochemical variables were evaluated yearly. Molecular expression profile of the somatostatin/ghrelin/dopamine regulatory systems components and of key pituitary factors and proliferation markers were evaluated in tumor samples after the first surgery., [Results] Clinical variables including tumor size, time until diagnosis/first surgery, serum prolactin, and postsurgery cortisol levels were associated with tumor remission and relapsed disease. The molecular markers analyzed were distinctly expressed in ACTHomas, with some components (ie, SSTR1, CRHR1, and MKI67) showing instructive associations with recurrence and/or remission. Notably, an integrative model including selected clinical variables (tumor size/postsurgery serum cortisol), and molecular markers (SSTR1/CRHR1) can accurately predict the clinical evolution and remission of patients with ACTHomas, generating a receiver operating characteristic curve with an area under the curve of 1 (P < .001)., [Conclusion] This study demonstrates that the combination of a set of clinical and molecular biomarkers in ACTHomas is able to accurately predict the clinical evolution and remission of patients. Consequently, the postsurgery molecular profile represents a valuable tool for clinical evaluation and follow-up of patients with ACTHomas.

Published
2022

41. Neuroendocrinology in 2011

Author

Puig Domingo, Manel, Castaño, Justo, Álvarez-Escolá, Cristina, Resmini, Eugenia, Venegas, Eva, García Arnés, Juan, Torres, Elena, Lecumberri, Beatriz, Barahona, María José, Lamas, Cristina, Fajardo, Carmen, Cámara, Rosa, Vicente, Almudena, Blanco, Concepción, Villabona, Carles, del Pozo, Carlos, Halperin, Irene, Salinas, Isabel, Sesmilo, Gemma, Aller, Javier, Marazuela, Mónica, Webb, Susan M., and Bernabeu, Ignacio

Published
2012
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42. Integrative Clinical, Radiological, and Molecular Analysis for Predicting Remission and Recurrence of Cushing Disease

Author

Moreno-Moreno, Paloma, primary, Ibáñez-Costa, Alejandro, additional, Venegas-Moreno, Eva, additional, Fuentes-Fayos, Antonio C, additional, Alhambra-Expósito, María R, additional, Fajardo-Montañana, Carmen, additional, García-Martínez, Araceli, additional, Dios, Elena, additional, Vázquez-Borrego, Mari C, additional, Remón-Ruiz, Pablo, additional, Cámara, Rosa, additional, Lamas, Cristina, additional, Carlos Padillo-Cuenca, José, additional, Solivera, Juan, additional, Cano, David A, additional, Gahete, Manuel D, additional, Herrera-Martínez, Aura D, additional, Picó, Antonio, additional, Soto-Moreno, Alfonso, additional, Gálvez-Moreno, María Ángeles, additional, Castaño, Justo P, additional, and Luque, Raúl M, additional

Published
2022
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43. Implications of Heterogeneity of Epithelial-Mesenchymal States in Acromegaly Therapeutic Pharmacologic Response

Author

Gil, Joan, primary, Marques-Pamies, Montserrat, additional, Valassi, Elena, additional, García-Martínez, Araceli, additional, Serra, Guillermo, additional, Hostalot, Cristina, additional, Fajardo-Montañana, Carmen, additional, Carrato, Cristina, additional, Bernabeu, Ignacio, additional, Marazuela, Mónica, additional, Rodríguez-Lloveras, Helena, additional, Cámara, Rosa, additional, Salinas, Isabel, additional, Lamas, Cristina, additional, Biagetti, Betina, additional, Simó-Servat, Andreu, additional, Webb, Susan M., additional, Picó, Antonio, additional, Jordà, Mireia, additional, and Puig-Domingo, Manel, additional

Published
2022
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44. Immunotherapy-induced isolated ACTH deficiency in cancer therapy

Author

Iglesias, Pedro, primary, Peiró, Inmaculada, additional, Biagetti, Betina, additional, Paja-Fano, Miguel, additional, Cobo, Diana Ariadel, additional, García Gómez, Carlos, additional, Mateu-Salat, Manuel, additional, Genua, Idoia, additional, Majem, Margarita, additional, Riudavets, Mariona, additional, Gavira, Javier, additional, Lamas, Cristina, additional, Fernández Pombo, Antía, additional, Guerrero-Pérez, Fernando, additional, Villabona, Carles, additional, Cabezas Agrícola, José Manuel, additional, Webb, Susan M, additional, and Díez, Juan J, additional

Published
2021
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45. Risk factors for intraoperative complications in pheochromocytomas

Author

Araujo-Castro, Marta, primary, Garcia Centeno, Rogelio, additional, López-García, María-Carmen, additional, Lamas, Cristina, additional, Álvarez-Escolá, Cristina, additional, Calatayud Gutiérrez, María, additional, Blanco-Carrera, Concepción, additional, de Miguel Novoa, Paz, additional, Valdés, Nuria, additional, Gracia Gimeno, Paola, additional, Fernández-Ladreda, Mariana Tomé, additional, Mínguez Ojeda, César, additional, Percovich Hualpa, Juan Carlos, additional, Mora, Mireia, additional, Vidal, Óscar, additional, Serrano Romero, Ana, additional, Hanzu, Felicia Alexandra, additional, and Gómez Dos Santos, Victoria, additional

Published
2021
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48. Cribado universal de gestantes de parto en la pandemia por COVID-19: Nuestra experiencia

Author

Tejada Lamas, Cristina, Arrieta Bretón, Sara, Ruiz Peña, Ana Cristina, Laguna Olmos, Mariano, García Fernández, José F., Puente Martínez, María José, Tejada Lamas, Cristina, Arrieta Bretón, Sara, Ruiz Peña, Ana Cristina, Laguna Olmos, Mariano, García Fernández, José F., and Puente Martínez, María José

Abstract

Since the beginning of the COVID-19 pandemic, the obstetric population has been considered a risk group, describing maternal-fetal complications arising from SARS-CoV-2 infection. Given the high cumulative incidence of COVID-19 cases and deaths in La Rioja at the beginning of the pandemic, a universal screening of pregnant women for the detection of SARS-CoV-2 was implemented in our hospital. Between March 30 and April 26, 2020, 130 women gave birth at our center. All of them were screened with RT-PCR test of nasopharyngeal exudate samples. 19 (14.6%) were positive, with no associated respiratory symptoms. Of the 111 negatives, 3 were positive during the puerperium, presenting fever and mild respiratory symptoms. Universal screening of pregnant women minimizes the risk of viral transmission by identifying and isolating asymptomatic cases, optimizes the use of health resources and establishes specific follow-up of patients., Desde el inicio de la pandemia por COVID-19, la población obstétrica se ha considerado grupo de riesgo, describiéndose complicaciones materno-fetales derivadas de la infección por SARS-CoV-2. Dada la alta tasa de incidencia acumulada de casos y muertes por COVID-19 en La Rioja al inicio de la pandemia, se implantó en nuestro hospital un cribado universal en gestantes para la detección del SARS-CoV-2. Entre el 30 de marzo y el 26 de abril de 2020, 130 mujeres dieron a luz en nuestro centro. Todas fueron cribadas con test RT-PCR de muestras de exudado nasofaríngeo. 19 (14,6%) fueron positivas, sin síntomas respiratorios asociados. De las 111 negativas, 3 positivizaron durante el puerperio, presentando fiebre y síntomas respiratorios leves. El cribado universal de gestantes permite minimizar el riesgo de transmisión vírica al identificar y aislar a los casos asintomáticos, optimizar el uso de recursos sanitarios y establecer un seguimiento específico de las pacientes.

Published
2021

49. Thymic neuroendocrine tumor and mortality in MEN 1 patients: the spanish registry

Author

Casteras, Anna, primary, Valdés, Nuria, additional, Lamas, Cristina, additional, Gaztambide, Sonia, additional, Paja, Fano Miguel, additional, Navarro, Elena, additional, Álvarez, Escol Cristina, additional, Diego, Estrella, additional, Calatayud, María, additional, Segura, Pedro, additional, Oriola, Josep, additional, and Spanish, group for the study of MEN and PPGL, additional

Published
2021
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50. El aprendizaje-servicio como pedagogía durante la pandemia. El proyecto 'UCA te da la Mano'

Author

Brenlla, María, Buzzini, Estefanía, González, Gabriela, Gómez, Claudia, Hermida, Juan, Lamas, Cristina, Pereyra, Fernanda, and García, María

Subjects
Service-learning, social commitment, higher education, psychology, front line staff, COVID 19, Aprendizaje-servicio, compromiso social, formación universitaria, psicología, personal de primera línea, COVID-19
Abstract

La Pontificia Universidad Católica Argentina (UCA) se ha propuesto articular y complementar la formación académica brindada a sus alumnos con una opción de vida auténtica, que los mueva a construir un mundo más justo dando respuestas a las demandas sociales de los sectores vulnerables de la sociedad. A partir de la pandemia ocasionada por el COVID-19, la UCA ha trabajado para dar respuesta a algunas de las nuevas problemáticas que hoy nos afectan. En esa línea se fueron desarrollando estrategias que nos permitieron continuar trabajando con la comunidad aún durante el período de aislamiento social, preventivo y obligatorio. En el marco del Programa ”UCA + Comunidad en época de pandemia” surge el proyecto “UCA te da la Mano”, realizado conjuntamente por el Departamento de Psicología de la Facultad de Psicología y Psicopedagogía y la Dirección de Compromiso Social y Extensión de la Pontificia Universidad Católica Argentina, el cual tiene el doble objetivo de brindar un espacio de reflexión y orientación para el personal de primera línea de respuesta y ser un espacio de aprendizaje para los alumnos de la carrera de psicología. Participan de ella, docentes, graduados y alumnos., One of the main objectives of Pontificia Universidad Católica Argentina (UCA) is to articulate and complement the academic training provided to its students with an authentic lifestyle choice , that would encourage them to build a fairer world by responding to the specific social demands coming from vulnerable sectors of society. The university has thus worked to respond to some of the new problems that now affect us as a society due to the COVID-19 pandemic. As a result, strategies have been developed to allow us to continue working with the community even during this period of social, preventive and compulsory isolation. Within the framework of the program ‘UCA + Comunidad en época de pandemia’ (UCA + Community in times of a pandemic), UCA has developed a project that we will discuss in this paper: ‘UCA te da la mano’ (UCA gives you a hand). The project, was jointly carried out by the Department of Psychology of the Faculty of Psychology and Psychopedagogy and the Directorate of Social Commitment and Outreach of the UCA, and it had a dual objective: providing a space for reflection and orientation for first-line response personnel and becoming a learning space for psychology students.

Published
2020

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