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1,731 results on '"Lane, Geoffrey"'

10. Impact of Epithelial Claudin-4 and Leukotriene B4 Receptor 2 in Normoganglionic Hirschsprung Disease Colon on Post Pull-through Enterocolitis

Author

Abe, Kumpei, Takeda, Masahiro, Ishiyama, Asuka, Shimizu, Masahiro, Goto, Hiroki, Iida, Hisae, Fujimoto, Takashi, Ueda-Abe, Eri, Yamada, Shunsuke, Fujiwara, Kentaro, Shibuya, Soichi, Ochi, Takanori, Arii, Rumi, Yazaki, Yuta, Miyano, Go, Urao, Masahiko, Okazaki, Tadaharu, Koga, Hiroyuki, Lane, Geoffrey J., Yamataka, Atsuyuki, and Suda, Kazuto

Published
2024
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11. Liver Mitochondrial Morphology and Gene Expression as Markers of Liver Reserve: Prognostic Implications for Native Liver Survival in Biliary Atresia

Author

Fujimoto, Takashi, Goto, Hiroki, Hida, Masataka, Tsuboi, Koichi, Suzuki, Takamasa, Iida, Hisae, Fukada, Ayaka, Shimizu, Sakika, Ebata, Yu, Nikai, Koki, Ishii, Junya, Takeda, Masahiro, Ishiyama, Asuka, Shibuya, Soichi, Yazaki, Yuta, Nakazawa-Tanaka, Nana, Miyano, Go, Okazaki, Tadaharu, Yanai, Toshihiro, Urao, Masahiko, Suzuki, Mitsuyoshi, Koga, Hiroyuki, Lane, Geoffrey J., Yamataka, Atsuyuki, and Suda, Kazuto

Published
2024
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26. Questioning the Correlation Between Incidence of Hirschsprung Disease and Indications for Rectal Biopsy.

Author

Miyano, Go, Suzuki, Takamasa, Masuda, Risa, Ito, Masaki, Iida, Hisae, Kaneko, Kotaro, Abe, Eri, Ikegami, Michiaki, Nikai, Koki, Ishii, Junya, Lane, Geoffrey J., Yamataka, Atsuyuki, and Okazaki, Tadaharu

Abstract

Aim: To review the indications for rectal mucosal/submucosal biopsy (RMSBx) used for diagnosing Hirschsprung's disease (HD) in pediatric patients. Methods: The medical records of all children between 1 and 15 years old assessed for chronic constipation between 2012 and 2022 were reviewed. Until the end of 2018, enema usage (E+) was a major indication for RMSBx. In 2019, laxative use for 3 months irrespective of enema use was added as an indication (L+). To determine the relevance of enema usage, L+ was subdivided by enema usage into (L+E+) and (L+E−) groups. The effect of changing the indications for RMSBx on the incidence of HD was investigated. Results: Of 562 eligible subjects, E+ = 410, L+ = 152; demographics are similar. RMSBx rate in E+ (E+RMSBx) was 36/410 (8.8%) and in L+ (L+RMSBx) was 42/152 (27.6%;) (P <.05). For L+RMSBx, 15/42 were L+E+ and 27/42 were L+E−. HD incidence in E+RMSBx was 8/36 (22.2%; E+HD) and in L+RMSBx was 13/42 (31.0%; L+HD) (p = ns). In L+RMSBx, HD incidence in L+E+ was 5/15 (33.3%; L+E+HD) and in L+E− was 8/27 (29.6%; L+E−HD) (P = ns). Differences in daily bowel motion frequency 6 months postoperatively were not statistically significant; E+HD (1.75/d) versus L+HD (2.03/d) and L+E+HD (1.60/day) versus L+E−HD (2.31/day). Unassisted voluntary defecation was confirmed 12 months postoperatively in 7/8 (87.5%) E+HD, 11/13 (84.6%) L+HD, 4/5 (80.0%) L+E+HD, and 7/8 (87.5%) L−E−HD; differences were not significant. Laxatives were still required in 2/8 (25.0%) E+HD, 3/13 (23.1%) L+HD, in 1/5 (20.0%) in L+E+HD, and 2/8 (25.0%) L+E−HD; differences were not significant. Conclusion: Incidence of HD was higher in L+HD, but not significantly different suggesting that indications for RMSBx have potential to influence incidence of HD and hint that the incidence of HD could actually be higher. Further assessment of additional indications is warranted to diagnose HD with greater accuracy. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Optical Trocar Access for Retroperitoneal Robotic-Assisted Pyeloplasty in Children with Ureteropelvic Junction Obstruction.

Author

Koga, Hiroyuki, Yamada, Shunsuke, Takeda, Masahiro, Ochi, Takanori, Seo, Shogo, Shibuya, Soichi, Yazaki, Yuta, Fujiwara, Naho, Arii, Rumi, Lane, Geoffrey J., and Yamataka, Atsuyuki

Abstract

Purpose: Retroperitoneal robotic-assisted pyeloplasty (ret-RAP) for ureteropelvic junction obstruction (UPJO) requires a larger retroperitoneal space (RS) to maintain specified distances between robotic (da Vinci) trocars and between trocars and the region of interest. A modified closed technique (MOT) and conventional closed technique (COT) were compared for creating an adequate RS with optical trocars. Methods: RS access in children with UPJO who underwent ret-RAP (n = 30) was MOT (n = 15) and COT (n = 15). All patients were positioned laterally. For MOT, a 5 mm optical trocar was inserted at the angle formed between the 12th rib and the erector spinae muscles. As the trocar was advanced under direct vision, it pierced the superficial subcutaneous layer, Scarpa's fascia, lumbar fascia, internal/external oblique and transversus abdominalis muscles, and the posterior renal fascia. Once in the RS, the tip of the scope was used for blunt dissection of perirenal fat, the tip was withdrawn until it was outside the perirenal fascia, and used to dissect toward the anterior abdomen in the pararenal fat layer. Results: Ages and weights at ret-RAP were similar (MOT: 5.6 ± 1.8 years versus COT: 7.8 ± 4.6 years; MOT: 20.6 ± 10.1 kg versus COT: 27.6 ± 13.9 kg). Times for RS access were similar (MOT: 1.6 ± 0.5 minutes versus COT: 1.9 ± 0.7 minutes), but RS expansion was significantly quicker in MOT (32.3 ± 8.7 minutes versus 52.0 ± 15.1 minutes; P < .001). Peritoneal injury caused carbon dioxide leakage in 4 of 15 COT cases and 0 of 15 MOT cases. Conclusion: RS expansion with MOT was safer because there were no peritoneal injuries and MOT was quicker than COT. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Biopsy Diagnosis of Hirschsprung's Disease Using a Single Excisional Biopsy Based on the Anorectal Line.

Author

Takeda, Masahiro, Ochi, Takanori, Koga, Hiroyuki, Tsuboi, Koichi, Arakawa, Atsushi, Lane, Geoffrey J., and Yamataka, Atsuyuki

Subjects
HIRSCHSPRUNG'S disease, BIOPSY, DIAGNOSIS, DEFECATION disorders
Abstract

Introduction A biopsy protocol for diagnosing Hirschsprung's disease (HD) in children using the anorectal line (ARL). Materials and Methods The ARL was adopted for diagnosing HD in 2016 using two excisional submucosal rectal biopsies performed at different levels, sequentially; the first just above the ARL and the second, further proximal (2-ARL). Currently, only the first-level biopsy is performed (1-ARL) and examined intraoperatively. Management was observation if normoganglionic, pull-through if aganglionic, and a second-level biopsy if hypoganglionic. Hypoganglionosis was considered physiologic if the second-level biopsy was normoganglionic and pathologic if hypoganglionic. Colon caliber change and bowel obstructive symptoms reflect the severity of hypoganglionosis. Results For 2-ARL (n = 54), results were: normoganglionosis (n = 31/54; 57.4%), aganglionosis (n = 19/54; 35.2%), and hypoganglionosis (n = 4/54; 7.4%); physiologic (n = 3/54; 5.6%) and pathologic (n = 1/54; 1.9%). Normoganglionosis and aganglionosis were always duplicated in 2-ARL (kappa = 1.0). For 1-ARL (n = 36), results were: normoganglionosis (n = 17/36; 47.2%), aganglionosis (n = 17/36; 47.2%), and hypoganglionosis (n = 2/36; 5.6%). Second-level biopsies were normoganglionic (physiologic: n = 1) and hypoganglionic (pathologic: n = 1). All normoganglionic cases, except one, resolved conservatively. All aganglionic cases had pull-through with HD confirmed on histopathology. Both pathologic hypoganglionic cases had caliber change and severe obstructive symptoms as definitive indications for pull-through with hypoganglionosis of the entire rectum confirmed on histopathology. Physiologic hypoganglionic cases were observed and currently have regular defecation. Conclusion Because the ARL is an objective functional, neurologic, and anatomic demarcation, normoganglionosis and aganglionosis can be diagnosed accurately with a single excisional biopsy. Only hypoganglionosis requires a second-level biopsy. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Remote cadaveric minimally invasive surgical training

Author

Miyano, Go, primary, Takahashi, Makoto, additional, Suzuki, Takamasa, additional, Iida, Hisae, additional, Abe, Eri, additional, Kato, Haruki, additional, Yoshida, Shiho, additional, Lane, Geoffrey J., additional, Ichimura, Koichiro, additional, Sakamoto, Kazuhiro, additional, Yamataka, Atsuyuki, additional, and Okazaki, Tadaharu, additional

Published
2023
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45. Comparative assessment of fully laparoscopic Duhamel-Z with minimal rectorectal dissection vs. laparoscopy-assisted Duhamel-Z with blunt manual rectorectal dissection for total colonic aganglionosis

Author

Miyano, Go, primary, Iida, Hisae, additional, Ebata, Yu, additional, Abe, Eri, additional, Kato, Haruki, additional, Mikami, Takafumi, additional, Ishii, Junya, additional, Lane, Geoffrey J., additional, Yamataka, Atsuyuki, additional, and Okazaki, Tadaharu, additional

Published
2023
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46. Gerontechnology

Author

Lane, Geoffrey, Haydell, Tyler, Simanski, Mersina, Stevenson, Cassandra, and Pachana, Nancy A., editor

Published
2017
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