249 results on '"Langley, David R."'
Search Results
2. PROTAC targeted protein degraders: the past is prologue
3. Targeting a Binding Pocket within the Trimer-of-Hairpins: Small-Molecule Inhibition of Viral Fusion
4. Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry
5. Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion: A Focus on Respiratory Syncytial Virus
6. Protein-Protein Interaction Targets to Inhibit HIV-1 Infection
7. Mutagenic Activation of Glutathione Peroxidase-4: Approaches toward Rational Design of Allosteric Drugs
8. Structure activity relationship studies of 3-arylsulfonyl-pyrido[1,2-a]pyrimidin-4-imines as potent 5-HT6 antagonists
9. Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A
10. Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers
11. Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase
12. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
13. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
14. The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors
15. Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068
16. Heterocycle amide isosteres: An approach to overcoming resistance for HIV-1 integrase strand transfer inhibitors
17. DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody–Drug Conjugate Modality
18. Discovery and Clinical Validation of HCV Inhibitors Targeting the NS5A Protein
19. Design, Synthesis, and Structure–Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody–Drug Conjugates
20. Discovery and Optimization of Novel Pyrazolopyrimidines as Potent and Orally Bioavailable Allosteric HIV-1 Integrase Inhibitors
21. Treatment of Counterions in Computer Simulations of DNA
22. Some Recent Developments in the Synthesis and Structure-Activity Relationship of Novel Taxanes
23. Sequential 1H, 13C, and 15N NMR assignments and solution conformation of apokedarcidin
24. Chemistry and structure elucidation of the kedarcidin chromophore
25. Uncialamycin as a novel payload for antibody drug conjugate (ADC) based targeted cancer therapy
26. A General Amino Acid Synthesis Enabled by Innate Radical Cross-Coupling
27. Homology models of the HIV-1 attachment inhibitor BMS-626529 bound to gp120 suggest a unique mechanism of action
28. Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir
29. Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir
30. Communication: Quantum polarized fluctuating charge model: A practical method to include ligand polarizability in biomolecular simulations.
31. Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir
32. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core
33. The terminal (catalytic) adenosine of the HIV LTR controls the kinetics of binding and dissociation of HIV integrase strand transfer inhibitors
34. Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529
35. A Functional NaV1.7-NaVAb Chimera with a Reconstituted High-Affinity ProTx-II Binding Site
36. Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors
37. Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir.
38. Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir
39. Discovery and Development of Hepatitis C Virus NS5A Replication Complex Inhibitors
40. Characterizations of HCV NS5A replication complex inhibitors
41. Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 12. Structure–Activity Relationships Associated with 4-Fluoro-6-azaindole Derivatives Leading to the Identification of 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248)
42. Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors.
43. Isolation, structure determination, and proposed mechanism of action for artifacts of maduropeptin chromophore
44. Balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-IR inhibitors
45. 2-(1 H-Imidazol-4-yl)ethanamine and 2-(1 H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924
46. Cloning, purification, crystallization and preliminary X-ray analysis of the catalytic domain of human receptor-like protein tyrosine phosphatase γ in three different crystal forms
47. In Vivo Patterns of Resistance to the HIV Attachment Inhibitor BMS-488043
48. MORPH: A New Tool for Ligand Design
49. Efficient synthesis of (Z)- and (E)-methyl 2-(methoxyimino)-2-phenylacetate
50. ChemInform Abstract: Nucleophilic Capture of the Imino-Quinone Methide Type Intermediates Generated from 2-Aminothiazol-5-yl Carbinols.
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.