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583 results on '"Languino, Lucia R."'

1. Role of Kindlin 2 in prostate cancer

Author

Bialkowska, Katarzyna, El Khalki, Lamyae, Rana, Priyanka S., Wang, Wei, Lindner, Daniel J., Parker, Yvonne, Languino, Lucia R., Altieri, Dario C., Pluskota, Elzbieta, Sossey-Alaoui, Khalid, and Plow, Edward F.

Published
2024
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2. Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer

Author

Testa, Anna, Quaglia, Fabio, Naranjo, Nicole M., Verrillo, Cecilia E., Shields, Christopher D., Lin, Stephen, Pickles, Maxwell W., Hamza, Drini F., Von Schalscha, Tami, Cheresh, David A., Leiby, Benjamin, Liu, Qin, Ding, Jianyi, Kelly, William K., Hooper, D. Craig, Corey, Eva, Plow, Edward F., Altieri, Dario C., and Languino, Lucia R.

Published
2023
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4. The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer

Author

Quaglia, Fabio, Krishn, Shiv Ram, Sossey-Alaoui, Khalid, Rana, Priyanka Shailendra, Pluskota, Elzbieta, Park, Pyung Hun, Shields, Christopher D., Lin, Stephen, McCue, Peter, Kossenkov, Andrew V., Wang, Yanqing, Goodrich, David W., Ku, Sheng-Yu, Beltran, Himisha, Kelly, William K., Corey, Eva, Klose, Maja, Bandtlow, Christine, Liu, Qin, Altieri, Dario C., Plow, Edward F., and Languino, Lucia R.

Published
2022
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5. Expression of the αVβ3 integrin affects prostate cancer sEV cargo and density and promotes sEV pro‐tumorigenic activity in vivo through a GPI‐anchored receptor, NgR2.

Author

Verrillo, Cecilia E., Quaglia, Fabio, Shields, Christopher D., Lin, Stephen, Kossenkov, Andrew V., Tang, Hsin‐Yao, Speicher, David, Naranjo, Nicole M., Testa, Anna, Kelly, William K., Liu, Qin, Leiby, Benjamin, Musante, Luca, Sossey‐Alaoui, Khalid, Dogra, Navneet, Chen, Tzu‐Yi, Altieri, Dario C., and Languino, Lucia R.

Subjects
FOCAL adhesion kinase, EXTRACELLULAR matrix, EXTRACELLULAR vesicles, CANCER cell proliferation, TETRASPANIN
Abstract

It is known that small extracellular vesicles (sEVs) are released from cancer cells and contribute to cancer progression via crosstalk with recipient cells. We have previously reported that sEVs expressing the αVβ3 integrin, a protein upregulated in aggressive neuroendocrine prostate cancer (NEPrCa), contribute to neuroendocrine differentiation (NED) in recipient cells. Here, we examine the impact of αVβ3 expression on sEV protein content, density and function. sEVs used in this study were isolated by iodixanol density gradients and characterized by nanoparticle tracking analysis, immunoblotting and single vesicle analysis. Our proteomic profile of sEVs containing αVβ3 shows downregulation of typical effectors involved in apoptosis and necrosis and an upregulation of tumour cell survival factors compared to control sEVs. We also show that the expression of αVβ3 in sEVs causes a distinct reposition of EV markers (Alix, CD81, CD9) to a low‐density sEV subpopulation. This low‐density reposition is independent of extracellular matrix (ECM) protein interactions with sEVs. This sEV subset contains αVβ3 and an αVβ3 downstream effector, NgR2, a novel marker for NEPrCa. We show that sEVs containing αVβ3 are loaded with higher amounts of NgR2 as compared to sEVs that do not express αVβ3. Mechanistically, we demonstrate that sEVs containing NgR2 do not affect the sEV marker profile, but when injected in vivo intratumorally, they promote tumour growth and induce NED. We show that sEVs expressing NgR2 increase the activation of focal adhesion kinase (FAK), a known promoter of cancer cell proliferation, in recipient cells. We also show that NgR2 mimics the effect of sEVs containing αVβ3 since it displays increased growth of NgR2 transfectants in vivo, as compared to control cells. Overall, our results describe the changes that occur in cargo, density and functions of cancer cell‐derived sEVs containing the αVβ3 integrin and its effector, NgR2, without affecting the sEV tetraspanin profiles. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Prostate cancer sheds the αvβ3 integrin in vivo through exosomes

Author

Krishn, Shiv Ram, Singh, Amrita, Bowler, Nicholas, Duffy, Alexander N., Friedman, Andrea, Fedele, Carmine, Kurtoglu, Senem, Tripathi, Sushil K., Wang, Kerith, Hawkins, Adam, Sayeed, Aejaz, Goswami, Chirayu P., Thakur, Madhukar L., Iozzo, Renato V., Peiper, Stephen C., Kelly, William K., and Languino, Lucia R.

Published
2019
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11. Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer

Author

Lu, Huimin, Bowler, Nicholas, Harshyne, Larry A., Craig Hooper, D., Krishn, Shiv Ram, Kurtoglu, Senem, Fedele, Carmine, Liu, Qin, Tang, Hsin-Yao, Kossenkov, Andrew V., Kelly, William K., Wang, Kerith, Kean, Rhonda B., Weinreb, Paul H., Yu, Lei, Dutta, Anindita, Fortina, Paolo, Ertel, Adam, Stanczak, Maria, Forsberg, Flemming, Gabrilovich, Dmitry I., Speicher, David W., Altieri, Dario C., and Languino, Lucia R.

Published
2018
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13. The Launch of the American Journal of Translational Research

Author

Lee, Wen-Hwa, Hung, Mien-Chie, Iczkowski, Kenneth A., Languino, Lucia R., Dubinett, Steven M., and Wang, Dengshun

Abstract

As we celebrate the New Year of 2009, we are pleased to announce that the American Journal of Translational Research has been launched with the strong support and enthusiastic participation of the editorial members and fellow investigators from the biomedical research community.

Published
2009

15. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors

Author

Kumar, Vinit, Donthireddy, Laxminarasimha, Marvel, Douglas, Condamine, Thomas, Wang, Fang, Lavilla-Alonso, Sergio, Hashimoto, Ayumi, Vonteddu, Prashanthi, Behera, Reeti, Goins, Marlee A., Mulligan, Charles, Nam, Brian, Hockstein, Neil, Denstman, Fred, Shakamuri, Shanti, Speicher, David W., Weeraratna, Ashani T., Chao, Timothy, Vonderheide, Robert H., Languino, Lucia R., Ordentlich, Peter, Liu, Qin, Xu, Xiaowei, Lo, Albert, Puré, Ellen, Zhang, Chunsheng, Loboda, Andrey, Sepulveda, Manuel A., Snyder, Linda A., and Gabrilovich, Dmitry I.

Published
2017
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16. Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma.

Author

Naranjo, Nicole M., Kennedy, Anne, Testa, Anna, Verrillo, Cecilia E., Altieri, Adrian D., Kean, Rhonda, Hooper, D. Craig, Yu, Jindan, Zhao, Jonathan, Abinader, Oliver, Pickles, Maxwell W., Hawkins, Adam, Kelly, William K., Mitra, Ramkrishna, and Languino, Lucia R.

Abstract

Prostate cancer has heterogeneous growth patterns, and its prognosis is the poorest when it progresses to a neuroendocrine phenotype. Using bioinformatic analysis, we evaluated RNA expression of neuroendocrine genes in a panel of five different cancer types: prostate adenocarcinoma, breast cancer, kidney chromophobe, kidney renal clear cell carcinoma and kidney renal papillary cell carcinoma. Our results show that specific neuroendocrine genes are significantly dysregulated in these tumors, suggesting that they play an active role in cancer progression. Among others, synaptophysin (SYP), a conventional neuroendocrine marker, is upregulated in prostate adenocarcinoma (PRAD) and breast cancer (BRCA). Our analysis shows that SYP is enriched in small extracellular vesicles (sEVs) derived from plasma of PRAD patients, but it is absent in sEVs derived from plasma of healthy donors. Similarly, classical sEV markers are enriched in sEVs derived from plasma of prostate cancer patients, but weakly detectable in sEVs derived from plasma of healthy donors. Overall, our results pave the way to explore new strategies to diagnose these diseases based on the neuroendocrine gene expression in patient tumors or plasma sEVs. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Unique pattern of neutrophil migration and function during tumor progression

Author

Patel, Sima, Fu, Shuyu, Mastio, Jerome, Dominguez, George A., Purohit, Abhilasha, Kossenkov, Andrew, Lin, Cindy, Alicea-Torres, Kevin, Sehgal, Mohit, Nefedova, Yulia, Zhou, Jie, Languino, Lucia R., Clendenin, Cynthia, Vonderheide, Robert H., Mulligan, Charles, Nam, Brian, Hockstein, Neil, Masters, Gregory, Guarino, Michael, Schug, Zachary T., Altieri, Dario C, and Gabrilovich, Dmitry I.

Published
2018
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18. Data from NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

Author

Raghavan, Kristopher S., primary, Francescone, Ralph, primary, Franco-Barraza, Janusz, primary, Gardiner, Jaye C., primary, Vendramini-Costa, Débora B., primary, Luong, Tiffany, primary, Pourmandi, Narges, primary, Andren, Anthony, primary, Kurimchak, Alison, primary, Ogier, Charline, primary, Campbell, Paul M., primary, Duncan, James S., primary, Lyssiotis, Costas A., primary, Languino, Lucia R., primary, and Cukierman, Edna, primary

Published
2023
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19. Supplementary Figures S1-S9 from NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

Author

Raghavan, Kristopher S., primary, Francescone, Ralph, primary, Franco-Barraza, Janusz, primary, Gardiner, Jaye C., primary, Vendramini-Costa, Débora B., primary, Luong, Tiffany, primary, Pourmandi, Narges, primary, Andren, Anthony, primary, Kurimchak, Alison, primary, Ogier, Charline, primary, Campbell, Paul M., primary, Duncan, James S., primary, Lyssiotis, Costas A., primary, Languino, Lucia R., primary, and Cukierman, Edna, primary

Published
2023
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20. Supplementary File 1 (proteomics) from NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

Author

Raghavan, Kristopher S., primary, Francescone, Ralph, primary, Franco-Barraza, Janusz, primary, Gardiner, Jaye C., primary, Vendramini-Costa, Débora B., primary, Luong, Tiffany, primary, Pourmandi, Narges, primary, Andren, Anthony, primary, Kurimchak, Alison, primary, Ogier, Charline, primary, Campbell, Paul M., primary, Duncan, James S., primary, Lyssiotis, Costas A., primary, Languino, Lucia R., primary, and Cukierman, Edna, primary

Published
2023
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21. Supplementary File 2 (statistical analyses) from NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

Author

Raghavan, Kristopher S., primary, Francescone, Ralph, primary, Franco-Barraza, Janusz, primary, Gardiner, Jaye C., primary, Vendramini-Costa, Débora B., primary, Luong, Tiffany, primary, Pourmandi, Narges, primary, Andren, Anthony, primary, Kurimchak, Alison, primary, Ogier, Charline, primary, Campbell, Paul M., primary, Duncan, James S., primary, Lyssiotis, Costas A., primary, Languino, Lucia R., primary, and Cukierman, Edna, primary

Published
2023
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22. Supplementary File 3 (metabolomics) from NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress

Author

Raghavan, Kristopher S., primary, Francescone, Ralph, primary, Franco-Barraza, Janusz, primary, Gardiner, Jaye C., primary, Vendramini-Costa, Débora B., primary, Luong, Tiffany, primary, Pourmandi, Narges, primary, Andren, Anthony, primary, Kurimchak, Alison, primary, Ogier, Charline, primary, Campbell, Paul M., primary, Duncan, James S., primary, Lyssiotis, Costas A., primary, Languino, Lucia R., primary, and Cukierman, Edna, primary

Published
2023
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27. Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

Author

Chae, Young Chan, Vaira, Valentina, Caino, M. Cecilia, Tang, Hsin-Yao, Seo, Jae Ho, Kossenkov, Andrew V., Ottobrini, Luisa, Martelli, Cristina, Lucignani, Giovanni, Bertolini, Irene, Locatelli, Marco, Bryant, Kelly G., Ghosh, Jagadish C., Lisanti, Sofia, Ku, Bonsu, Bosari, Silvano, Languino, Lucia R., Speicher, David W., and Altieri, Dario C.

Published
2016
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29. Supplementary Figure 1 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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31. Data from v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1

Author

Ju, Xiaoming, primary, Jiao, Xuanmao, primary, Ertel, Adam, primary, Casimiro, Mathew C., primary, Di Sante, Gabriele, primary, Deng, Shengqiong, primary, Li, Zhiping, primary, Di Rocco, Agnese, primary, Zhan, Tingting, primary, Hawkins, Adam, primary, Stoyanova, Tanya, primary, Andò, Sebastiano, primary, Fatatis, Alessandro, primary, Lisanti, Michael P., primary, Gomella, Leonard G., primary, Languino, Lucia R., primary, and Pestell, Richard G., primary

Published
2023
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32. Supplementary Figure 3 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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33. Data from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

Author

Seo, Jae Ho, primary, Chae, Young Chan, primary, Kossenkov, Andrew V., primary, Lee, Yu Geon, primary, Tang, Hsin-Yao, primary, Agarwal, Ekta, primary, Gabrilovich, Dmitry I., primary, Languino, Lucia R., primary, Speicher, David W., primary, Shastrula, Prashanth K., primary, Storaci, Alessandra Maria, primary, Ferrero, Stefano, primary, Gaudioso, Gabriella, primary, Caroli, Manuela, primary, Tosi, Davide, primary, Giroda, Massimo, primary, Vaira, Valentina, primary, Rebecca, Vito W., primary, Herlyn, Meenhard, primary, Xiao, Min, primary, Fingerman, Dylan, primary, Martorella, Alessandra, primary, Skordalakes, Emmanuel, primary, and Altieri, Dario C., primary

Published
2023
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34. Supplementary Data from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

Author

Seo, Jae Ho, primary, Chae, Young Chan, primary, Kossenkov, Andrew V., primary, Lee, Yu Geon, primary, Tang, Hsin-Yao, primary, Agarwal, Ekta, primary, Gabrilovich, Dmitry I., primary, Languino, Lucia R., primary, Speicher, David W., primary, Shastrula, Prashanth K., primary, Storaci, Alessandra Maria, primary, Ferrero, Stefano, primary, Gaudioso, Gabriella, primary, Caroli, Manuela, primary, Tosi, Davide, primary, Giroda, Massimo, primary, Vaira, Valentina, primary, Rebecca, Vito W., primary, Herlyn, Meenhard, primary, Xiao, Min, primary, Fingerman, Dylan, primary, Martorella, Alessandra, primary, Skordalakes, Emmanuel, primary, and Altieri, Dario C., primary

Published
2023
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35. Supplemental Methos from v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1

Author

Ju, Xiaoming, primary, Jiao, Xuanmao, primary, Ertel, Adam, primary, Casimiro, Mathew C., primary, Di Sante, Gabriele, primary, Deng, Shengqiong, primary, Li, Zhiping, primary, Di Rocco, Agnese, primary, Zhan, Tingting, primary, Hawkins, Adam, primary, Stoyanova, Tanya, primary, Andò, Sebastiano, primary, Fatatis, Alessandro, primary, Lisanti, Michael P., primary, Gomella, Leonard G., primary, Languino, Lucia R., primary, and Pestell, Richard G., primary

Published
2023
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36. Supplemental Material from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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37. Supplementary Figure 6 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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38. Supplementary Figure 9 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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39. Supplementary Figure 4 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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40. Figure S5 from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

Author

Seo, Jae Ho, primary, Chae, Young Chan, primary, Kossenkov, Andrew V., primary, Lee, Yu Geon, primary, Tang, Hsin-Yao, primary, Agarwal, Ekta, primary, Gabrilovich, Dmitry I., primary, Languino, Lucia R., primary, Speicher, David W., primary, Shastrula, Prashanth K., primary, Storaci, Alessandra Maria, primary, Ferrero, Stefano, primary, Gaudioso, Gabriella, primary, Caroli, Manuela, primary, Tosi, Davide, primary, Giroda, Massimo, primary, Vaira, Valentina, primary, Rebecca, Vito W., primary, Herlyn, Meenhard, primary, Xiao, Min, primary, Fingerman, Dylan, primary, Martorella, Alessandra, primary, Skordalakes, Emmanuel, primary, and Altieri, Dario C., primary

Published
2023
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41. Supplementary Figure 7 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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42. Supplementary Movie S2 from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

Author

Seo, Jae Ho, primary, Chae, Young Chan, primary, Kossenkov, Andrew V., primary, Lee, Yu Geon, primary, Tang, Hsin-Yao, primary, Agarwal, Ekta, primary, Gabrilovich, Dmitry I., primary, Languino, Lucia R., primary, Speicher, David W., primary, Shastrula, Prashanth K., primary, Storaci, Alessandra Maria, primary, Ferrero, Stefano, primary, Gaudioso, Gabriella, primary, Caroli, Manuela, primary, Tosi, Davide, primary, Giroda, Massimo, primary, Vaira, Valentina, primary, Rebecca, Vito W., primary, Herlyn, Meenhard, primary, Xiao, Min, primary, Fingerman, Dylan, primary, Martorella, Alessandra, primary, Skordalakes, Emmanuel, primary, and Altieri, Dario C., primary

Published
2023
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43. Table S2 from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

Author

Seo, Jae Ho, primary, Chae, Young Chan, primary, Kossenkov, Andrew V., primary, Lee, Yu Geon, primary, Tang, Hsin-Yao, primary, Agarwal, Ekta, primary, Gabrilovich, Dmitry I., primary, Languino, Lucia R., primary, Speicher, David W., primary, Shastrula, Prashanth K., primary, Storaci, Alessandra Maria, primary, Ferrero, Stefano, primary, Gaudioso, Gabriella, primary, Caroli, Manuela, primary, Tosi, Davide, primary, Giroda, Massimo, primary, Vaira, Valentina, primary, Rebecca, Vito W., primary, Herlyn, Meenhard, primary, Xiao, Min, primary, Fingerman, Dylan, primary, Martorella, Alessandra, primary, Skordalakes, Emmanuel, primary, and Altieri, Dario C., primary

Published
2023
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44. Supplementary Figure S1 from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

Author

Seo, Jae Ho, primary, Chae, Young Chan, primary, Kossenkov, Andrew V., primary, Lee, Yu Geon, primary, Tang, Hsin-Yao, primary, Agarwal, Ekta, primary, Gabrilovich, Dmitry I., primary, Languino, Lucia R., primary, Speicher, David W., primary, Shastrula, Prashanth K., primary, Storaci, Alessandra Maria, primary, Ferrero, Stefano, primary, Gaudioso, Gabriella, primary, Caroli, Manuela, primary, Tosi, Davide, primary, Giroda, Massimo, primary, Vaira, Valentina, primary, Rebecca, Vito W., primary, Herlyn, Meenhard, primary, Xiao, Min, primary, Fingerman, Dylan, primary, Martorella, Alessandra, primary, Skordalakes, Emmanuel, primary, and Altieri, Dario C., primary

Published
2023
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46. Supplementary Figure 2 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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47. Supplemental Figures from v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1

Author

Ju, Xiaoming, primary, Jiao, Xuanmao, primary, Ertel, Adam, primary, Casimiro, Mathew C., primary, Di Sante, Gabriele, primary, Deng, Shengqiong, primary, Li, Zhiping, primary, Di Rocco, Agnese, primary, Zhan, Tingting, primary, Hawkins, Adam, primary, Stoyanova, Tanya, primary, Andò, Sebastiano, primary, Fatatis, Alessandro, primary, Lisanti, Michael P., primary, Gomella, Leonard G., primary, Languino, Lucia R., primary, and Pestell, Richard G., primary

Published
2023
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48. Data from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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50. Supplementary Figure 8 from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

Author

Lu, Huimin, primary, Wang, Tao, primary, Li, Jing, primary, Fedele, Carmine, primary, Liu, Qin, primary, Zhang, Jianzhong, primary, Jiang, Zhong, primary, Jain, Dhanpat, primary, Iozzo, Renato V., primary, Violette, Shelia M., primary, Weinreb, Paul H., primary, Davis, Roger J., primary, Gioeli, Daniel, primary, FitzGerald, Thomas J., primary, Altieri, Dario C., primary, and Languino, Lucia R., primary

Published
2023
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