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Sexually transmitted infections (STIs) are a significant public health concern across the globe. Vaccines have played a crucial role in mitigating the burden of infectious diseases and are the most effective candidates for preventing STIs. Currently, vaccines for hepatitis A, hepatitis B virus (HBV), and human papillomavirus (HPV) are available. More recently, the smallpox vaccine was approved for Mpox (MPX) prevention. Ongoing research efforts are focused on developing vaccines for other STIs. This paper reviews the current indications for available vaccines for use in the context of STIs and discusses some of the vaccines currently being researched.

The article discusses a case of generalized hyperpigmented and hypopigmented macules and papules in a 49-year-old woman. The patient had these skin lesions since her twenties and mentioned that her family members also had similar lesions. The physical examination revealed oval hyperpigmented macules and papules, some with a hyperkeratotic surface, along with hypopigmented macules. Histopathological examination showed characteristic features of Dowling-Degos disease (DDD), a rare genodermatosis. The article provides information on the clinical presentation, histological findings, genetic analysis, and differential diagnosis of DDD. Treatment options for DDD are also discussed. [Extracted from the article]