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The aim of the following work was to design a biosensor for the detection of ethanol. A biosensor is an analytical device in which a biological sensing element is connected to or integrated with a physical transducing element. Amperometric enzyme biosensors utilise one or more enzymes to convert a substance which cannot be measured electrochemically to one which can be. In the case of an alcohol biosensor one of two enzymes (alcohol dehydrogenase and alcohol oxidase) can be used to convert electrochemically stable alcohol to either hydrogen peroxide or NADH which can be oxidised. In the design of an alcohol biosensor there are three major variables to consider, these are; enzyme type, electrode material, and immobilisation technique. The goal was to select optimum conditions for the formulation of the desired sensor. In the present work the electrode materials used were platinum, carbon (foil and paste) and the conducting organic salt N-methyl phenazinium.Tetracyanoquinodimethane (NMP.TCNQ). The immobilisation techniques used were; adsorption, cross-linking to a protein matrix and covalent binding. Of the biosensors produced from a selected combination or these variables each was tested by one or more of the following; cyclic voltammetry, enzyme assay, and amperometry. The most promising approach appears to be that of conjugating enzyme to haemin and allowing the conjugate to bind irreversibly to platinum via the haemin group. An electrode made with the organic salt NMP.TCNQ looked promising also but because the salt is readily oxidised it is unstable and therefore not an ideal electrode material.

Clive Sansom (1910-1981), poet and speech educator, was born at Finchley, North London, in 1910. He worked as a clerk and salesman in London and studied speech and drama under Marjorie Gullan at the Polytechnic, Regent Street, and the Speech Institute (1930-35) and phonetics under Professor Daniel Jones at University College, London (1935-6). He lectured in speech training at Borough Road Training College, Isleworth, and the Speech Fellowship (1937-9) and edited the Speech Fellowship Bulletin (1934-49). He was instructor in the Drama School of the London Academy of Music and Dramatic Art (LAMDA) and examiner in speech and spoken poetry.In 1937 he married a fellow student and speech teacher, Ruth Large from Tasmania. Although neither was at the time a Quaker, they were married in the Friends Meeting House at Winchmore Hill. They were both interested in the Society of Friends and had attended a few Meetings. Clive's teacher and friend, Marjorie Gullan, was a Quaker. Soon they both joined the Friends.In 1949 Clive and Ruth Sansom travelled to Hobart to visit Ruth's family and decided to settle in Tasmania. Clive was appointed, with Ruth, Supervisor of Speech Education for the Tasmanian Education Department and was responsible for the Speech Centre 1950-1965 and was also examiner in speech and drama for the A.M.E.B. He and Ruth broadcast and wrote scripts for the ABC. programs for primary schools. Clive also wrote or edited a number of short plays for schools.

Clive Sansom (1910-1981), poet and speech educator, was born at Finchley, North London, in 1910. He worked as a clerk and salesman in London and studied speech and drama under Marjorie Gullan at the Polytechnic, Regent Street, and the Speech Institute (1930-35) and phonetics under Professor Daniel Jones at University College, London (1935-6). He lectured in speech training at Borough Road Training College, Isleworth, and the Speech Fellowship (1937-9) and edited the Speech Fellowship Bulletin (1934-49). He was instructor in the Drama School of the London Academy of Music and Dramatic Art (LAMDA) and examiner in speech and spoken poetry.In 1937 he married a fellow student and speech teacher, Ruth Large from Tasmania. Although neither was at the time a Quaker, they were married in the Friends Meeting House at Winchmore Hill. They were both interested in the Society of Friends and had attended a few Meetings. Clive's teacher and friend, Marjorie Gullan, was a Quaker. Soon they both joined the Friends.In 1949 Clive and Ruth Sansom travelled to Hobart to visit Ruth's family and decided to settle in Tasmania. Clive was appointed, with Ruth, Supervisor of Speech Education for the Tasmanian Education Department and was responsible for the Speech Centre 1950-1965 and was also examiner in speech and drama for the A.M.E.B. He and Ruth broadcast and wrote scripts for the ABC. programs for primary schools. Clive also wrote or edited a number of short plays for schools.

Clive Sansom (1910-1981), poet and speech educator, was born at Finchley, North London, in 1910. He worked as a clerk and salesman in London and studied speech and drama under Marjorie Gullan at the Polytechnic, Regent Street, and the Speech Institute (1930-35) and phonetics under Professor Daniel Jones at University College, London (1935-6). He lectured in speech training at Borough Road Training College, Isleworth, and the Speech Fellowship (1937-9) and edited the Speech Fellowship Bulletin (1934-49). He was instructor in the Drama School of the London Academy of Music and Dramatic Art (LAMDA) and examiner in speech and spoken poetry.In 1937 he married a fellow student and speech teacher, Ruth Large from Tasmania. Although neither was at the time a Quaker, they were married in the Friends Meeting House at Winchmore Hill. They were both interested in the Society of Friends and had attended a few Meetings. Clive's teacher and friend, Marjorie Gullan, was a Quaker. Soon they both joined the Friends.In 1949 Clive and Ruth Sansom travelled to Hobart to visit Ruth's family and decided to settle in Tasmania. Clive was appointed, with Ruth, Supervisor of Speech Education for the Tasmanian Education Department and was responsible for the Speech Centre 1950-1965 and was also examiner in speech and drama for the A.M.E.B. He and Ruth broadcast and wrote scripts for the ABC. programs for primary schools. Clive also wrote or edited a number of short plays for schools.

Clive Sansom (1910-1981), poet and speech educator, was born at Finchley, North London, in 1910. He worked as a clerk and salesman in London and studied speech and drama under Marjorie Gullan at the Polytechnic, Regent Street, and the Speech Institute (1930-35) and phonetics under Professor Daniel Jones at University College, London (1935-6). He lectured in speech training at Borough Road Training College, Isleworth, and the Speech Fellowship (1937-9) and edited the Speech Fellowship Bulletin (1934-49). He was instructor in the Drama School of the London Academy of Music and Dramatic Art (LAMDA) and examiner in speech and spoken poetry.In 1937 he married a fellow student and speech teacher, Ruth Large from Tasmania. Although neither was at the time a Quaker, they were married in the Friends Meeting House at Winchmore Hill. They were both interested in the Society of Friends and had attended a few Meetings. Clive's teacher and friend, Marjorie Gullan, was a Quaker. Soon they both joined the Friends.In 1949 Clive and Ruth Sansom travelled to Hobart to visit Ruth's family and decided to settle in Tasmania. Clive was appointed, with Ruth, Supervisor of Speech Education for the Tasmanian Education Department and was responsible for the Speech Centre 1950-1965 and was also examiner in speech and drama for the A.M.E.B. He and Ruth broadcast and wrote scripts for the ABC. programs for primary schools. Clive also wrote or edited a number of short plays for schools.