40 results on '"Larsen, Sofus Christian"'
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2. Intake of n-3 LCPUFA and trans-fatty acids is unrelated to development in body mass index and body fat among children
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Ren, Xuan, Larsen, Sofus Christian, Lauritzen, Lotte, Rohde, Jeanett Friis, Andersen, Lars Bo, Bugge, Anna, Jensen, Britt Wang, Specht, Ina Olmer, and Heitmann, Berit Lilienthal
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- 2022
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3. Co-designing a weight-neutral health intervention in Denmark: a protocol paper (Preprint)
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Meyer, Lene, primary, Køster-Rasmussen, Rasmus, additional, Christiansen, Ann-Kathrin Lindahl, additional, Heitmann, Berit Lilienthal, additional, Vesterlund, Gitte Kingo, additional, Larsen, Sofus Christian, additional, Specht, Ina Olmer, additional, Þorsteinsdóttir, Fanney, additional, Steinbo, Emma Katrine Frøhlke, additional, Appel, Clara Lundmark, additional, Reventlow, Susanne, additional, Waldorff, Frans Boch, additional, and Sandholdt, Catharina Thiel, additional
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- 2024
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4. Types of kindergarten and their relationship with parental and children’s socio-demographic characteristics in Denmark
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Specht, Ina Olmer, primary, Larsen, Sofus Christian, additional, Nielsen, Ann-Kristine, additional, Rohde, Jeanett Friis, additional, Heitmann, Berit Lilienthal, additional, and Jørgensen, Tanja Schjødt, additional
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- 2023
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5. Data from Prospective Population-Based Study of the Association between Serum 25-Hydroxyvitamin-D Levels and the Incidence of Specific Types of Cancer
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Skaaby, Tea, primary, Husemoen, Lise Lotte Nystrup, primary, Thuesen, Betina Heinsbæk, primary, Pisinger, Charlotta, primary, Jørgensen, Torben, primary, Roswall, Nina, primary, Larsen, Sofus Christian, primary, and Linneberg, Allan, primary
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- 2023
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6. Supplementary Tables 1 and 2 from Prospective Population-Based Study of the Association between Serum 25-Hydroxyvitamin-D Levels and the Incidence of Specific Types of Cancer
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Skaaby, Tea, primary, Husemoen, Lise Lotte Nystrup, primary, Thuesen, Betina Heinsbæk, primary, Pisinger, Charlotta, primary, Jørgensen, Torben, primary, Roswall, Nina, primary, Larsen, Sofus Christian, primary, and Linneberg, Allan, primary
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- 2023
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7. Outdoor Kindergartens: A Structural Way to Improve Early Physical Activity Behaviour?
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Rohde, Jeanett Friis, primary, Larsen, Sofus Christian, additional, Sederberg, Mathilde, additional, Bahrenscheer, Anne, additional, Nielsen, Ann-Kristine, additional, Heitmann, Berit Lilienthal, additional, and Specht, Ina Olmer, additional
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- 2023
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8. Types of kindergarten and their relationship with parental and children's socio-demographic characteristics in Denmark
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Specht, Ina Olmer, Larsen, Sofus Christian, Nielsen, Ann Kristine, Rohde, Jeanett Friis, Heitmann, Berit Lilienthal, Jørgensen, Tanja Schjødt, Specht, Ina Olmer, Larsen, Sofus Christian, Nielsen, Ann Kristine, Rohde, Jeanett Friis, Heitmann, Berit Lilienthal, and Jørgensen, Tanja Schjødt
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In Danish outdoor kindergartens, children are spending most of the day outdoors often in forests or similar nature environments. These children are assumed to be healthier than children attending conventional kindergartens, however, factors related to choosing a specific type of kindergarten may explain the differences. To better understand this, we aimed to investigate parents reasons for choosing either outdoor or conventional kindergartens based on a mixed-method participatory Concept Mapping approach, and further if parental socio-demographics and early child characteristics differed prior to enrolling children to either type of kindergarten using a cohort register-based approach. Parents of children attending outdoor kindergartens (n = 23) weighed reasons such as “physical setting, outdoor life, and freedom of movement” high, whereas “a good first impression of the kindergarten” was an important reason for parents choosing a conventional kindergarten (n = 22). In the register-based approach, 2434 and 2643 children attended outdoor or conventional kindergartens, respectively. The parents choosing outdoor kindergartens as well as their children differed according to most investigated characteristics, including origin (maternal non-Western: 4.2% vs. 21.9%, p < .0001), educational level (maternal long education: 45.6% vs. 33.0%, p < .0001), prematurity (5.1% vs. 7.1%, p = 0.004) and sex (females: 43.5% vs. 48.6%, p = <0.0013). In conclusion, parental reasons for choosing kindergarten as well as parental socio-demographics differed substantially among kindergarten type. These differences might cause selection bias if not considering when comparing health outcomes among children attending different kinds of kindergartens., In Danish outdoor kindergartens, children are spending most of the day outdoors often in forests or similar nature environments. These children are assumed to be healthier than children attending conventional kindergartens, however, factors related to choosing a specific type of kindergarten may explain the differences. To better understand this, we aimed to investigate parents reasons for choosing either outdoor or conventional kindergartens based on a mixed-method participatory Concept Mapping approach, and further if parental socio-demographics and early child characteristics differed prior to enrolling children to either type of kindergarten using a cohort register-based approach. Parents of children attending outdoor kindergartens (n = 23) weighed reasons such as “physical setting, outdoor life, and freedom of movement” high, whereas “a good first impression of the kindergarten” was an important reason for parents choosing a conventional kindergarten (n = 22). In the register-based approach, 2434 and 2643 children attended outdoor or conventional kindergartens, respectively. The parents choosing outdoor kindergartens as well as their children differed according to most investigated characteristics, including origin (maternal non-Western: 4.2% vs. 21.9%, p < .0001), educational level (maternal long education: 45.6% vs. 33.0%, p < .0001), prematurity (5.1% vs. 7.1%, p = 0.004) and sex (females: 43.5% vs. 48.6%, p = <0.0013). In conclusion, parental reasons for choosing kindergarten as well as parental socio-demographics differed substantially among kindergarten type. These differences might cause selection bias if not considering when comparing health outcomes among children attending different kinds of kindergartens.
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- 2023
9. Does attendance in outdoor kindergartens reduce the use of antibiotics in children?
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Olsen, Nanna Julie, Larsen, Sofus Christian, Køster-Rasmussen, Rasmus, Rohde, Jeanett Friis, Østergaard, Jane Nautrup, Heitmann, Berit Lilienthal, Specht, Ina Olmer, Olsen, Nanna Julie, Larsen, Sofus Christian, Køster-Rasmussen, Rasmus, Rohde, Jeanett Friis, Østergaard, Jane Nautrup, Heitmann, Berit Lilienthal, and Specht, Ina Olmer
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Aim The aim of this study was to determine whether children enrolled in rural outdoor kindergartens had a lower risk of redeeming at least one prescription for antibiotics compared with children enrolled in urban conventional kindergartens, and if type of antibiotics prescribed differed according to kindergarten type. Methods Two Danish municipalities provided data including civil registration numbers from children enrolled in a rural outdoor kindergarten in 2011–2019, and a subsample of all children enrolled in urban conventional kindergartens in the same period. Civil registration numbers were linked to individual-level information on redeemed prescriptions for antibiotics from the Danish National Prescription Registry. Regression models were performed on 2132 children enrolled in outdoor kindergartens, and 2208 children enrolled in conventional kindergartens. Results There was no difference between groups in risk of redeeming at least one prescription for all types of antibiotics (adjusted risk ratio: 0.97 [95% confidence intervals 0.93, 1.02, p = 0.26]). Similarly, there were no differences between kindergarten type and risk of redeeming at least one prescription for systemic, narrow-spectrum systemic antibacterial, broad-spectrum systemic antibacterial or topical antibiotics. Conclusion Compared with children who were enrolled in conventional kindergartens, children who were enrolled in outdoor kindergartens did not have a lower risk of redeeming prescriptions for any type of antibiotics., Aim: The aim of this study was to determine whether children enrolled in rural outdoor kindergartens had a lower risk of redeeming at least one prescription for antibiotics compared with children enrolled in urban conventional kindergartens, and if type of antibiotics prescribed differed according to kindergarten type. Methods: Two Danish municipalities provided data including civil registration numbers from children enrolled in a rural outdoor kindergarten in 2011–2019, and a subsample of all children enrolled in urban conventional kindergartens in the same period. Civil registration numbers were linked to individual-level information on redeemed prescriptions for antibiotics from the Danish National Prescription Registry. Regression models were performed on 2132 children enrolled in outdoor kindergartens, and 2208 children enrolled in conventional kindergartens. Results: There was no difference between groups in risk of redeeming at least one prescription for all types of antibiotics (adjusted risk ratio: 0.97 [95% confidence intervals 0.93, 1.02, p = 0.26]). Similarly, there were no differences between kindergarten type and risk of redeeming at least one prescription for systemic, narrow-spectrum systemic antibacterial, broad-spectrum systemic antibacterial or topical antibiotics. Conclusion: Compared with children who were enrolled in conventional kindergartens, children who were enrolled in outdoor kindergartens did not have a lower risk of redeeming prescriptions for any type of antibiotics.
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- 2023
10. Larsen, Sofus Christian
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Larsen, Sofus Christian and Larsen, Sofus Christian
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- 2023
11. Comparison of Motor Difficulties Measured in the First Year of School among Children Who Attended Rural Outdoor or Urban Conventional Kindergartens
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Specht, Ina Olmer, primary, Larsen, Sofus Christian, additional, Rohde, Jeanett Friis, additional, Østergaard, Jane Nautrup, additional, and Heitmann, Berit Lilienthal, additional
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- 2022
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12. Comparison of Motor Difficulties Measured in the First Year of School among Children Who Attended Rural Outdoor or Urban Conventional Kindergartens
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Specht, Ina Olmer, Larsen, Sofus Christian, Rohde, Jeanett Friis, Ostergaard, Jane Nautrup, Heitmann, Berit Lilienthal, Specht, Ina Olmer, Larsen, Sofus Christian, Rohde, Jeanett Friis, Ostergaard, Jane Nautrup, and Heitmann, Berit Lilienthal
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Background: Kindergartens can potentially contribute substantially to the daily level of physical activity and development of motor skills and might be an ideal setting for improving these as a public health initiative. We aimed to examine whether children from rural outdoor kindergartens had a lower risk of motor difficulties than children from urban conventional kindergartens. Methods: Motor test results were measured during the first school year by school health nurses using a six-item test of gross- and fine motor skills (jumping, handle a writing tool, cutting with a scissor following a line, one-leg stand on each leg, throwing and grabbing). Register-based information was available on potential confounding factors. Results: We included 901 children from outdoor kindergartens and 993 from conventional kindergartens with a mean (SD) age of 6.5 years (0.4). The children from the two types of kindergarten differed according to demographic information, with outdoor kindergarten children more often being from more affluent families (long maternal education level: 47.5% vs. 31.0%, p < 0.0001) and fewer girls attending the outdoor kindergartens (42.7% vs. 49.5%, p = 0.003). In the adjusted models, we found no evidence of differences in the risk of motor difficulties between children attending either type of kindergarten (OR: 0.95, 95%CI: 0.71; 1.27, p = 0.72). Conclusion: Our results do not support outdoor kindergartens as a potential intervention to improve motor abilities among children. Randomized controlled trials are needed to confirm these findings.
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- 2022
13. Effects of the healthy start randomized intervention on psychological stress and sleep habits among obesity-susceptible healthy weight children and their parents
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Olsen, Nanna Julie, Larsen, Sofus Christian, Rohde, Jeanett Friis, Stougaard, Maria, Handel, Mina Nicole, Specht, Ina Olmer, Heitmann, Berit Lilienthal, Olsen, Nanna Julie, Larsen, Sofus Christian, Rohde, Jeanett Friis, Stougaard, Maria, Handel, Mina Nicole, Specht, Ina Olmer, and Heitmann, Berit Lilienthal
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Poor sleep and psychological stress are obesity determinants that are rarely included in obesity prevention programs. The aim was to report the effects of the Healthy Start randomized intervention on the secondary outcomes psychological stress and sleep duration and onset latency. Data was obtained from the Healthy Start randomized intervention conducted in 2009-2012 among Danish healthy weight children aged 2-6 years, who had either a high birth weight (>4,000 g), high maternal pre-pregnancy body mass index (>28 kg/m(2)), or low maternal educational level (
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- 2022
14. Physical Activity and Subsequent Change in Body Weight, Composition and Shape:Effect Modification by Familial Overweight
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Specht, Ina Olmer, Heitmann, Berit Lilienthal, Larsen, Sofus Christian, Specht, Ina Olmer, Heitmann, Berit Lilienthal, and Larsen, Sofus Christian
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BackgroundPhysical activity (PA) has been shown to attenuate the genetic risk of obesity as measured using polygenic risk scores. However, familial obesity history might be an easier predictor. We examined associations between PA and subsequent changes in BMI, body fat percentage (BF%) and waist circumference (WC) among participants with and without adiposity and a familial overweight. MethodsIn total, 1971 participants from the Danish MONICA cohort were included. Mean differences for 6-year changes in BMI, BF% and WC across PA levels were estimated. Association between walking and biking and subsequent change in adiposity were analysed. Effect modification by familial obesity was assessed by adding product terms to the models. ResultsWe observed weak associations between leisure PA level and changes in WC [participants with low PA: 3.4 cm (95%CI: 2.8;4.0), participants with high PA: 2.4 cm (95%CI: 1.8;3.0)], with no evidence of effect modification by familial obesity. We found effect modification in analyses on walking and biking in relation to changes in BMI (P-interaction
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- 2022
15. Effects of the healthy start randomized intervention on psychological stress and sleep habits among obesity-susceptible healthy weight children and their parents
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Olsen, Nanna Julie, primary, Larsen, Sofus Christian, additional, Rohde, Jeanett Friis, additional, Stougaard, Maria, additional, Händel, Mina Nicole, additional, Specht, Ina Olmer, additional, and Heitmann, Berit Lilienthal, additional
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- 2022
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16. Physical Activity and Subsequent Change in Body Weight, Composition and Shape: Effect Modification by Familial Overweight
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Specht, Ina Olmer, primary, Heitmann, Berit Lilienthal, additional, and Larsen, Sofus Christian, additional
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- 2022
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17. Additional file 1 of Intake of n-3 LCPUFA and trans-fatty acids is unrelated to development in body mass index and body fat among children
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Ren, Xuan, Larsen, Sofus Christian, Lauritzen, Lotte, Rohde, Jeanett Friis, Andersen, Lars Bo, Bugge, Anna, Jensen, Britt Wang, Specht, Ina Olmer, and Heitmann, Berit Lilienthal
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Data_FILES - Abstract
Additional file 1.
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- 2022
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18. Effect of PEP flute self-care versus usual care in early covid-19: non-drug, open label, randomised controlled trial in a Danish community setting
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Mollerup, Annette, primary, Henriksen, Marius, additional, Larsen, Sofus Christian, additional, Bennetzen, Anita Selmer, additional, Simonsen, Mette Kildevæld, additional, Kofod, Linette Marie, additional, Knudsen, Jenny Dahl, additional, Nielsen, Xiaohui Chen, additional, Weis, Nina, additional, and Heitmann, Berit Lilienthal, additional
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- 2021
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19. Three-Year Intervention Effects on Food and Beverage Intake—Results from the Quasi-Experimental Copenhagen School Child Intervention Study (CoSCIS)
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Ren, Xuan, primary, Jensen, Britt Wang, additional, Larsen, Sofus Christian, additional, Rohde, Jeanett Friis, additional, Specht, Ina Olmer, additional, Nielsen, Birgit Marie, additional, Husby, Ida, additional, Bugge, Anna, additional, Andersen, Lars Bo, additional, Trolle, Ellen, additional, and Heitmann, Berit Lilienthal, additional
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- 2021
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20. PEP-CoV protocol: a PEP flute-self-care randomised controlled trial to prevent respiratory deterioration and hospitalisation in early COVID-19
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Mollerup, Annette, primary, Larsen, Sofus Christian, additional, Bennetzen, Anita Selmer, additional, Henriksen, Marius, additional, Simonsen, Mette Kildevaeld, additional, Weis, Nina, additional, Kofod, Linette Marie, additional, and Heitmann, Berit Lilienthal, additional
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- 2021
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21. Changes in Emotional-Behavioral Functioning Among Pre-school Children Following the Initial Stage Danish COVID-19 Lockdown and Home Confinement
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Specht, Ina Olmer, primary, Rohde, Jeanett Friis, additional, Nielsen, Ann-Kristine, additional, Larsen, Sofus Christian, additional, and Heitmann, Berit Lilienthal, additional
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- 2021
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22. Three-year intervention effects on food and beverage intake— results from the quasi-experimental copenhagen school child intervention study (Coscis)
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Ren, Xuan, Jensen, Britt Wang, Larsen, Sofus Christian, Rohde, Jeanett Friis, Specht, Ina Olmer, Nielsen, Birgit Marie, Husby, Ida, Bugge, Anna, Andersen, Lars Bo, Trolle, Ellen, Heitmann, Berit Lilienthal, Ren, Xuan, Jensen, Britt Wang, Larsen, Sofus Christian, Rohde, Jeanett Friis, Specht, Ina Olmer, Nielsen, Birgit Marie, Husby, Ida, Bugge, Anna, Andersen, Lars Bo, Trolle, Ellen, and Heitmann, Berit Lilienthal
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The diet of Danish children is often not in accordance with dietary guidelines. We aimed to evaluate changes in the intake of selected foods and beverages during a multi-component school-based physical activity intervention, and to investigate if changes were modified by socioeconomic status (SES). The study included 307 children (intervention group: 184; comparison group: 123) with information on dietary intake pre-and post-intervention as well as on SES. Linear regression models were conducted to assess the effect of the intervention on changes in dietary factors. Children from the intervention group increased their intake of whole-grain bread during the intervention (group means: 6.1 g/d (95% CI: 2.2 to 10.0) vs. 0.3 g/d (95% CI:-3.1 to 3.7) in the comparison group, p = 0.04). A significant interaction between SES and group allocation was observed to change in fruit intake (p = 0.01). Among children from low SES families, only those from the comparison group decreased their fruit intake (group means:-40.0 g/d (95% CI-56.0 to-23.9) vs. 9.3 g/d (95% CI-16.1 to 94) in the intervention group, p = 0.006). The present study found no convincing effect of introducing a multi-component intervention on dietary intake except a small beneficial effect on whole-grain bread consumption. However, beneficial intervention effects in fruit intake were found particularly among children from low SES families.
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- 2021
23. Effect of PEP flute self-care versus usual care in early covid-19:Non-drug, open label, randomised controlled trial in a Danish community setting
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Mollerup, Annette, Henriksen, Marius, Larsen, Sofus Christian, Bennetzen, Anita Selmer, Simonsen, Mette Kildevæld, Kofod, Linette Marie, Knudsen, Jenny Dahl, Nielsen, Xiaohui Chen, Weis, Nina, Heitmann, Berit Lilienthal, Mollerup, Annette, Henriksen, Marius, Larsen, Sofus Christian, Bennetzen, Anita Selmer, Simonsen, Mette Kildevæld, Kofod, Linette Marie, Knudsen, Jenny Dahl, Nielsen, Xiaohui Chen, Weis, Nina, and Heitmann, Berit Lilienthal
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OBJECTIVE To determine whether positive expiratory pressure (PEP) by PEP flute self-care is effective in reducing respiratory symptoms among community dwelling adults with SARS-CoV-2 infection and early stage covid-19. DESIGN Non-drug, open label, randomised controlled trial. SETTING Capital Region and Region Zealand in Denmark from 6 October 2020 to 26 February 2021. PARTICIPANTS Community dwelling adults, able to perform self-care, with a new SARS-CoV-2 infection (verified by reverse transcription polymerase chain reaction tests) and symptoms of covid-19. INTERVENTION Participants were randomised to use PEP flute self-care in addition to usual care or have usual care only. Randomisation was based on permuted random blocks in a 1:1 ratio, stratified for sex and age (<60 or ≥60 years). The PEP self-care group was instructed to use a PEP flute three times per day during the 30 day intervention. MAIN OUTCOME MEASURES Primary outcome was a change in symptom severity from baseline to day 30, as assessed by the self-reported COPD (chronic obstructive pulmonary disease) assessment test (CAT), which was adjusted for baseline values and stratification factors. Participants completed the CAT test questionnaire every day online. Secondary outcomes were self-reported urgent care visits due to covid-19, number of covid-19 related symptoms, and change in self-rated health, all within 30-days’ follow-up. RESULTS 378 participants were assigned to the PEP flute self-care intervention (n=190) or usual care only (n=188). In the PEP self-care group, the median number of days with PEP flute use was 21 days (interquartile range 13-25). For the intention-to-treat population, a group difference was observed in changes from baseline in CAT scores of −1.2 points (95% confidence interval −2.1 to −0.2; P=0.017) in favour of the PEP flute self-care group. At day 30, the PEP flute self-care group also reported less chest tightness, less dyspnoea, more vigour, and higher level of daily act
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- 2021
24. PEP-CoV protocol:a PEP flute-self-care randomised controlled trial to prevent respiratory deterioration and hospitalisation in early COVID-19
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Mollerup, Annette, Larsen, Sofus Christian, Bennetzen, Anita Selmer, Henriksen, Marius, Simonsen, Mette Kildevæld, Weis, Nina, Kofod, Linette Marie, Heitmann, Berit Lilienthal, Mollerup, Annette, Larsen, Sofus Christian, Bennetzen, Anita Selmer, Henriksen, Marius, Simonsen, Mette Kildevæld, Weis, Nina, Kofod, Linette Marie, and Heitmann, Berit Lilienthal
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INTRODUCTION: Infection with SARS-CoV-2 may progress to severe pulmonary disease, COVID-19. Currently, patients admitted to hospital because of COVID-19 have better prognosis than during the first period of the pandemic due to improved treatment. However, the overall societal susceptibility of being infected makes it pivotal to prevent severe courses of disease to avoid high mortality rates and collapse of the healthcare systems. Positive expiratory pressure (PEP) self-care is used in chronic pulmonary disease and has been shown to prevent pneumonia in a high-risk cohort of patients with leukaemia. PEP flute self-care to prevent respiratory deterioration and hospitalisation in early COVID-19: a randomised trial (The PEP-CoV trial) examines the effectiveness on respiratory symptoms and need of hospital admission by regular PEP flute use among non-hospitalised individuals with confirmed SARS-CoV-2 infection and COVID-19 symptoms. METHODS AND ANALYSIS: In this randomised controlled trial, we hypothesise that daily PEP flute usage as add-on to usual care is superior to usual care as regards symptom severity measured by the COPD Assessment Test (CAT) at 30-day follow-up (primary outcome) and hospital admission through register data (secondary outcome). We expect to recruit 400 individuals for the trial. Participants in the intervention group receive a kit of 2 PEP flutes and adequate resistances and access to instruction videos. A telephone hotline offers possible contact to a nurse. The eight-item CAT score measures cough, phlegm, chest tightness, dyspnoea, activities of daily living at home, feeling safe at home despite symptoms, sleep quality and vigour. The CAT score is measured daily in both intervention and control arms by surveys prompted through text messages. ETHICS AND DISSEMINATION: The study was registered prospectively at www.clinicaltrials.gov on 27 August 2020 (NCT04530435). Ethical approval was granted by the local health research ethics committee (Jou
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- 2021
25. Changes in Emotional-Behavioral Functioning Among Pre-school Children Following the Initial Stage Danish COVID-19 Lockdown and Home Confinement
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Specht, Ina Olmer, Rohde, Jeanett Friis, Nielsen, Ann-Kristine, Larsen, Sofus Christian, Heitmann, Befit Lilienthal, Specht, Ina Olmer, Rohde, Jeanett Friis, Nielsen, Ann-Kristine, Larsen, Sofus Christian, and Heitmann, Befit Lilienthal
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Unintended negative outcomes on child behavior due to lockdown and home confinement following the corona virus disease (COVID-19) pandemic needs highlighting to effectively address these issues in the current and future health crises. In this sub-study of the ODIN-study, the objectives were to determine whether the Danish lockdown and home confinement following the COVID-19 pandemic affected changes in emotional-behavioral functioning of pre-school-aged children using the validated Strength and Difficulties Questionnaire (SDQ) answered by parents shortly before lockdown and 3 weeks into lockdown, and moreover, to examine whether baseline family and social characteristics could predict change in child emotional-behavioral functioning during lockdown. Parents of 40 (82%) children with a mean(SD) age of 5.0(0.7) completed the baseline questionnaire and the lockdown follow-up questionnaire. The SDQ-Total difficulties score (SDQ-TD) and Prosocial Behavioral score (PSB) changed significantly from pre- to lockdown [SDQ-TD mean(SD): 6.0(3.8) and 7.9(5.2); P = 0.02, respectively and PSB mean(SD): 8.5(1.4) and 7.9(1.5); P = 0.03, respectively]. Attending leisure time activities before lockdown was a predicting factor of changes to the worse in the children's SDQ-TD scores, with a mean difference in SDQ-TD between those with and without activities of 3.16 (95%CI 0.27-6.12); P = 0.03. In conclusion, the study showed a modest decrease in child-emotional behavioral functioning during the COVID-19 lockdown, potentially due to parental stress. Although these results might not be generalizable due to small sample size and selected population, the results point to a need of a greater awareness of child mental wellbeing during a lockdown situation.
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- 2021
26. Associations between parental stress and subsequent changes in dietary intake and quality among preschool children susceptible to obesity
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Rohde, Jeanett Friis, Larsen, Sofus Christian, Händel, Mina Nicole, Olsen, Nanna Julie, Stougaard, Maria, Heitmann, Berit Lilienthal, Rohde, Jeanett Friis, Larsen, Sofus Christian, Händel, Mina Nicole, Olsen, Nanna Julie, Stougaard, Maria, and Heitmann, Berit Lilienthal
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Background: Cross-sectional studies indicate that parental stress may be a barrier for healthy dietary behaviours among children. However, there is a lack of evidence from longitudinal studies on the association between parental stress and changes in dietary intake among toddlers. The aim of this study was to examine the association between parental stress and changes in dietary intake and quality among preschool children susceptible to obesity. Methods: In the Healthy Start study, parents to 250 preschool children had completed a modified version of the Parental Stress Index and assessed the dietary intake of their children at baseline and after 15 months of follow up. The association between parental stress and changes in dietary intake and quality was examined using multiple linear regression analyses with adjustment for potential confounders. We tested for potential effect modification by group allocation and sex. Results: There were no significant associations between parental stress and subsequent changes in child total energy intake, intake of macronutrients or intake of fruit, vegetables, sugar sweetened beverages, fish or starch, or dietary quality. Conclusion: This study provides no evidence to support an association between parental stress and subsequent change in dietary intake and quality of their children. Trial registration: ClinicalTrials.gov, Trial number: NCT01583335, Registered: 31 March 2012, retrospectively registered.
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- 2021
27. Associations between Parental Stress and Subsequent Changes in Dietary Intake and Quality among Preschool Children Susceptible to Obesity
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Rohde, Jeanett Friis, primary, Larsen, Sofus Christian, additional, Händel, Mina Nicole, additional, Olsen, Nanna Julie, additional, Stougaard, Maria, additional, and Heitmann, Berit Lilienthal, additional
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- 2021
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28. Effect of PEP Flute-Selfcare Versus Usual Care in Early COVID-19: A Non-Pharmacological, Open-Label, Randomised Trial
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Mollerup, Annette, primary, Henriksen, Marius, additional, Larsen, Sofus Christian, additional, Bennetzen, Anita Selmer, additional, Simonsen, Mette Kildevaeld, additional, Kofod, Linette Marie, additional, Knudsen, Jenny Dahl, additional, Nielsen, Xiaohui Chen, additional, Weis, Nina, additional, and Heitmann, Berit Lillienthal, additional
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- 2021
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29. Coffee drinking and mortality in 10 European countries : A multinational cohort study
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Gunter, Marc J., Murphy, Neil, Cross, Amanda J., Dossus, Laure, Dartois, Laureen, Fagherazzi, Guy, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Larsen, Sofus Christian, Cornejo, Maria Luisa Redondo, Agudo, Antonio, Pérez, María José Sánchez, Altzibar, Jone M., Navarro, Carmen, Ardanaz, Eva, Khaw, Kay Tee, Butterworth, Adam, Bradbury, Kathryn E., Trichopoulou, Antonia, Lagiou, Pagona, Trichopoulos, Dimitrios, Palli, Domenico, Grioni, Sara, Vineis, Paolo, Panico, Salvatore, Tumino, Rosario, Bueno-De-Mesquita, Bas, Siersema, Peter, Leenders, Max, Beulens, Joline W.J., Uiterwaal, Cuno U., Wallström, Peter, Nilsson, Lena Maria, Landberg, Rikard, Weiderpass, Elisabete, Skeie, Guri, Braaten, Tonje, Brennan, Paul, Licaj, Idlir, Muller, David C., Sinha, Rashmi, Wareham, Nick, Riboli, Elio, Gunter, Marc J., Murphy, Neil, Cross, Amanda J., Dossus, Laure, Dartois, Laureen, Fagherazzi, Guy, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Larsen, Sofus Christian, Cornejo, Maria Luisa Redondo, Agudo, Antonio, Pérez, María José Sánchez, Altzibar, Jone M., Navarro, Carmen, Ardanaz, Eva, Khaw, Kay Tee, Butterworth, Adam, Bradbury, Kathryn E., Trichopoulou, Antonia, Lagiou, Pagona, Trichopoulos, Dimitrios, Palli, Domenico, Grioni, Sara, Vineis, Paolo, Panico, Salvatore, Tumino, Rosario, Bueno-De-Mesquita, Bas, Siersema, Peter, Leenders, Max, Beulens, Joline W.J., Uiterwaal, Cuno U., Wallström, Peter, Nilsson, Lena Maria, Landberg, Rikard, Weiderpass, Elisabete, Skeie, Guri, Braaten, Tonje, Brennan, Paul, Licaj, Idlir, Muller, David C., Sinha, Rashmi, Wareham, Nick, and Riboli, Elio
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- 2017
30. Coffee drinking and mortality in 10 European countries: A multinational cohort study
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MS MDL 1, Cancer, Epi Methoden Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Gunter, Marc J., Murphy, Neil, Cross, Amanda J., Dossus, Laure, Dartois, Laureen, Fagherazzi, Guy, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Larsen, Sofus Christian, Cornejo, Maria Luisa Redondo, Agudo, Antonio, Pérez, María José Sánchez, Altzibar, Jone M., Navarro, Carmen, Ardanaz, Eva, Khaw, Kay Tee, Butterworth, Adam, Bradbury, Kathryn E., Trichopoulou, Antonia, Lagiou, Pagona, Trichopoulos, Dimitrios, Palli, Domenico, Grioni, Sara, Vineis, Paolo, Panico, Salvatore, Tumino, Rosario, Bueno-De-Mesquita, Bas, Siersema, Peter, Leenders, Max, Beulens, Joline W.J., Uiterwaal, Cuno U., Wallström, Peter, Nilsson, Lena Maria, Landberg, Rikard, Weiderpass, Elisabete, Skeie, Guri, Braaten, Tonje, Brennan, Paul, Licaj, Idlir, Muller, David C., Sinha, Rashmi, Wareham, Nick, Riboli, Elio, MS MDL 1, Cancer, Epi Methoden Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Gunter, Marc J., Murphy, Neil, Cross, Amanda J., Dossus, Laure, Dartois, Laureen, Fagherazzi, Guy, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Larsen, Sofus Christian, Cornejo, Maria Luisa Redondo, Agudo, Antonio, Pérez, María José Sánchez, Altzibar, Jone M., Navarro, Carmen, Ardanaz, Eva, Khaw, Kay Tee, Butterworth, Adam, Bradbury, Kathryn E., Trichopoulou, Antonia, Lagiou, Pagona, Trichopoulos, Dimitrios, Palli, Domenico, Grioni, Sara, Vineis, Paolo, Panico, Salvatore, Tumino, Rosario, Bueno-De-Mesquita, Bas, Siersema, Peter, Leenders, Max, Beulens, Joline W.J., Uiterwaal, Cuno U., Wallström, Peter, Nilsson, Lena Maria, Landberg, Rikard, Weiderpass, Elisabete, Skeie, Guri, Braaten, Tonje, Brennan, Paul, Licaj, Idlir, Muller, David C., Sinha, Rashmi, Wareham, Nick, and Riboli, Elio
- Published
- 2017
31. EFFECTS ON DIET INTAKE FROM THE HEALTHY START PRIMARY INTERVENTION
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Rohde, Jeanett Friis, Larsen, Sofus Christian, Lars, Angquist, Olsen, Nanna Julie, Stougaard, Maria, Mortensen, Erik Lykke, Heitmann, Berit Lilienthal, Rohde, Jeanett Friis, Larsen, Sofus Christian, Lars, Angquist, Olsen, Nanna Julie, Stougaard, Maria, Mortensen, Erik Lykke, and Heitmann, Berit Lilienthal
- Published
- 2017
32. Effects of the Healthy Start randomized intervention trial on physical activity among normal weight preschool children predisposed to overweight and obesity
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Händel, Mina Nicole, Larsen, Sofus Christian, Rohde, Jeanett Friis, Stougaard, Maria, Olsen, Nanna Julie, Heitmann, Berit Lilienthal, Händel, Mina Nicole, Larsen, Sofus Christian, Rohde, Jeanett Friis, Stougaard, Maria, Olsen, Nanna Julie, and Heitmann, Berit Lilienthal
- Abstract
Background: There is limited evidence to support the effectiveness of primary interventions aiming to prevent excess weight gain among young children. Evaluating behavioral changes, such as physical activity (PA), may add to future development of efficient interventions. The objective was to evaluate the effect on PA outcomes of the 15 month Healthy Start intervention that focused on changing diet, PA, sleep and stress management among normal weight but obesity-prone preschool children. Children were defined as obesity-prone if they had a birth weight > 4,000 g, mothers with a pre-pregnancy body mass index of > 28 kg/m2, or mothers with ≤ 10 years of schooling.Method: From a baseline study population of 635 normal weight 2–6 year old preschool children from the greater Copenhagen area, parents of 307 children had given information on PA at both the baseline and follow-up examinations. PA was obtained from a 7 days recording in the Children’s Physical Activity Questionnaire. Time used for sport activities were combined with outdoor playing time to achieve a proxy of total PA level of moderate to vigorous intensity.Results: Linear regression analyses revealed that at follow-up the intervention group spent more time on sports and outdoor activities combined per week than the control group (ITT analyses: intervention: 400 min/week; 95% confidence interval (CI): 341, 459 versus control: 321 min/week; 95% CI: 277, 366; p = 0.02), although no significant intervention effects were seen for each of the subcategories, e.g. sports participation, outdoor activities, screen time, or commuting frequency.Conclusion: Our results suggest that the overall time spent on sports and outdoor activities combined was increased at follow-up among normal weight obesity-prone children, as a result of the Healthy Start intervention. Trial registration: ClinicalTrials.gov NCT01583335, Background: There is limited evidence to support the effectiveness of primary interventions aiming to prevent excess weight gain among young children. Evaluating behavioral changes, such as physical activity (PA), may add to future development of efficient interventions. The objective was to evaluate the effect on PA outcomes of the 15 month Healthy Start intervention that focused on changing diet, PA, sleep and stress management among normal weight but obesity-prone preschool children. Children were defined as obesity-prone if they had a birth weight > 4,000 g, mothers with a pre-pregnancy body mass index of > 28 kg/m2, or mothers with ≤ 10 years of schooling. Method: From a baseline study population of 635 normal weight 2–6 year old preschool children from the greater Copenhagen area, parents of 307 children had given information on PA at both the baseline and follow-up examinations. PA was obtained from a 7 days recording in the Children’s Physical Activity Questionnaire. Time used for sport activities were combined with outdoor playing time to achieve a proxy of total PA level of moderate to vigorous intensity.Results: Linear regression analyses revealed that at follow-up the intervention group spent more time on sports and outdoor activities combined per week than the control group (ITT analyses: intervention: 400 min/week; 95% confidence interval (CI): 341, 459 versus control: 321 min/week; 95% CI: 277, 366; p = 0.02), although no significant intervention effects were seen for each of the subcategories, e.g. sports participation, outdoor activities, screen time, or commuting frequency. Conclusion: Our results suggest that the overall time spent on sports and outdoor activities combined was increased at follow-up among normal weight obesity-prone children, as a result of the Healthy Start intervention. Trial registration: ClinicalTrials.gov NCT01583335.
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- 2017
33. Effects of the Healthy Start randomized intervention trial on physical activity among normal weight preschool children predisposed to overweight and obesity
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Händel, Mina Nicole, primary, Larsen, Sofus Christian, additional, Rohde, Jeanett Friis, additional, Stougaard, Maria, additional, Olsen, Nanna Julie, additional, and Heitmann, Berit Lilienthal, additional
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- 2017
- Full Text
- View/download PDF
34. Coffee Drinking and Mortality in 10 European Countries
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Gunter, Marc J., primary, Murphy, Neil, additional, Cross, Amanda J., additional, Dossus, Laure, additional, Dartois, Laureen, additional, Fagherazzi, Guy, additional, Kaaks, Rudolf, additional, Kühn, Tilman, additional, Boeing, Heiner, additional, Aleksandrova, Krasimira, additional, Tjønneland, Anne, additional, Olsen, Anja, additional, Overvad, Kim, additional, Larsen, Sofus Christian, additional, Redondo Cornejo, Maria Luisa, additional, Agudo, Antonio, additional, Sánchez Pérez, María José, additional, Altzibar, Jone M., additional, Navarro, Carmen, additional, Ardanaz, Eva, additional, Khaw, Kay-Tee, additional, Butterworth, Adam, additional, Bradbury, Kathryn E., additional, Trichopoulou, Antonia, additional, Lagiou, Pagona, additional, Trichopoulos, Dimitrios, additional, Palli, Domenico, additional, Grioni, Sara, additional, Vineis, Paolo, additional, Panico, Salvatore, additional, Tumino, Rosario, additional, Bueno-de-Mesquita, Bas, additional, Siersema, Peter, additional, Leenders, Max, additional, Beulens, Joline W.J., additional, Uiterwaal, Cuno U., additional, Wallström, Peter, additional, Nilsson, Lena Maria, additional, Landberg, Rikard, additional, Weiderpass, Elisabete, additional, Skeie, Guri, additional, Braaten, Tonje, additional, Brennan, Paul, additional, Licaj, Idlir, additional, Muller, David C., additional, Sinha, Rashmi, additional, Wareham, Nick, additional, and Riboli, Elio, additional
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- 2017
- Full Text
- View/download PDF
35. Prospective Population-Based Study of the Association between Serum 25-Hydroxyvitamin-D Levels and the Incidence of Specific Types of Cancer
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Skaaby, Tea, Husemoen, Lise Lotte Nystrup, Thuesen, Betina Heinsbæk, Pisinger, Charlotta, Jørgensen, Torben, Roswall, Nina, Larsen, Sofus Christian, Linneberg, Allan, Skaaby, Tea, Husemoen, Lise Lotte Nystrup, Thuesen, Betina Heinsbæk, Pisinger, Charlotta, Jørgensen, Torben, Roswall, Nina, Larsen, Sofus Christian, and Linneberg, Allan
- Abstract
BACKGROUND: Observational studies have suggested an inverse association between vitamin D status and cancer. We investigated the prospective associations between vitamin D status and the total and specific type of cancer in three cohorts from the general Danish population.METHODS: A total of 12,204 individuals 18 to 71 years old were included. The level of 25-hydroxyvitamin D was measured at baseline, and information about cancer was obtained from the Danish Cancer Registry.RESULTS: During the 11.3-year median follow-up time, there were 1,248 incident cancers. HRs [95% confidence intervals (CI)] per 10 nmol/L higher baseline vitamin D level were: for all cancers (HR = 1.02; 95% CI, 0.99-1.04), all cancers excluding non-melanoma skin cancer, NMSC (HR = 1.00; 95% CI, 0.97-1.03), head and neck cancer (HR = 0.97; 95% CI, 0.84-1.12), colorectal cancer (HR = 0.95; 95% CI, 0.88-1.02), cancer of bronchus and lung (HR = 0.98; 95% CI, 0.91-1.05), breast cancer (HR = 1.02; 95% CI, 0.96-1.09), cancer of the uterus (HR = 1.10; 95% CI, 0.95-1.27), prostate cancer (HR = 1.00; 95% CI, 0.93-1.08), cancer of the urinary organs (HR = 1.01; 95% CI, 0.90-1.14), NMSC (HR = 1.06; 95% CI, 1.02-1.10), and malignant melanoma (HR = 1.06; 95% CI, 0.95-1.17).CONCLUSIONS: Apart from a significantly higher risk for NMSC with higher vitamin D status, we found no statistically significant associations between vitamin D status and total or specific cancers.IMPACT: Our results do not indicate that there is an impact of vitamin D on total cancer incidence.
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- 2014
36. Prospective Population-Based Study of the Association between Serum 25-Hydroxyvitamin-D Levels and the Incidence of Specific Types of Cancer
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Skaaby, Tea, primary, Husemoen, Lise Lotte Nystrup, additional, Thuesen, Betina Heinsbæk, additional, Pisinger, Charlotta, additional, Jørgensen, Torben, additional, Roswall, Nina, additional, Larsen, Sofus Christian, additional, and Linneberg, Allan, additional
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- 2014
- Full Text
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37. 24h urinary sodium excretion and subsequent change in weight, waist circumference and body composition
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Larsen, Sofus Christian, Ängquist, Lars, Sørensen, Thorkild I A, Heitmann, Berit L, Larsen, Sofus Christian, Ängquist, Lars, Sørensen, Thorkild I A, and Heitmann, Berit L
- Published
- 2013
38. Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study
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Tilman Kühn, Neil Murphy, Tonje Braaten, Rudolf Kaaks, Jone M. Altzibar, Guy Fagherazzi, María José Pérez, Adam S. Butterworth, Peter Wallström, Heiner Boeing, Maria Luisa Redondo Cornejo, Antonia Trichopoulou, Peter D. Siersema, Krasimira Aleksandrova, Laureen Dartois, Dimitrios Trichopoulos, Max Leenders, Paul Brennan, Pagona Lagiou, Kathryn E. Bradbury, Eva Ardanaz, Carmen Navarro, Guri Skeie, Rosario Tumino, Bas Bueno-de-Mesquita, Elisabete Weiderpass, Amanda J. Cross, Elio Riboli, Lena Maria Nilsson, Antonio Agudo, Sara Grioni, Rikard Landberg, Joline W.J. Beulens, Kim Overvad, Anne Tjønneland, Laure Dossus, Rashmi Sinha, Marc J. Gunter, Paolo Vineis, David C. Muller, Nicholas J. Wareham, Anja Olsen, Salvatore Panico, Sofus C. Larsen, Cuno U Uiterwaal, Kay-Tee Khaw, Idlir Licaj, Domenico Palli, Epidemiology and Data Science, APH - Health Behaviors & Chronic Diseases, ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, Gunter, Marc J., Murphy, Neil, Cross, Amanda J., Dossus, Laure, Dartois, Laureen, Fagherazzi, Guy, Kaaks, Rudolf, Kã¼hn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Tjã¸nneland, Anne, Olsen, Anja, Overvad, Kim, Larsen, Sofus Christian, Cornejo, Maria Luisa Redondo, Agudo, Antonio, Pã©rez, Marãa Josã© Sã¡nchez, Altzibar, Jone M., Navarro, Carmen, Ardanaz, Eva, Khaw, Kay tee, Butterworth, Adam, Bradbury, Kathryn E., Trichopoulou, Antonia, Lagiou, Pagona, Trichopoulos, Dimitrio, Palli, Domenico, Grioni, Sara, Vineis, Paolo, Panico, Salvatore, Tumino, Rosario, Bueno de mesquita, Ba, Siersema, Peter, Leenders, Max, Beulens, Joline W. J., Uiterwaal, Cuno U., Wallstrã¶m, Peter, Nilsson, Lena Maria, Landberg, Rikard, Weiderpass, Elisabete, Skeie, Guri, Braaten, Tonje, Brennan, Paul, Licaj, Idlir, Muller, David C., Sinha, Rashmi, Wareham, Nick, Riboli, Elio, Khaw, Kay-Tee [0000-0002-8802-2903], Butterworth, Adam [0000-0002-6915-9015], Wareham, Nicholas [0000-0003-1422-2993], Apollo - University of Cambridge Repository, and Imperial College Trust
- Subjects
Male ,Center of excellence ,030204 cardiovascular system & hematology ,CORONARY HEART-DISEASE ,Coffee ,Institut Gustave Roussy ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Liver Function Tests ,Risk Factors ,Cardiovascular Disease ,Cause of Death ,TEA CONSUMPTION ,Medicine ,030212 general & internal medicine ,IOWA WOMENS HEALTH ,Prospective Studies ,media_common ,Ovarian Neoplasms ,Liver Function Test ,DECAFFEINATED COFFEE ,General Medicine ,11 Medical And Health Sciences ,respiratory system ,Middle Aged ,C-REACTIVE PROTEIN ,Europe ,CARDIOVASCULAR-DISEASE ,Cardiovascular Diseases ,Cerebrovascular Disorder ,language ,Female ,Life Sciences & Biomedicine ,Cohort study ,Human ,Adult ,medicine.medical_specialty ,CAFFEINE ,media_common.quotation_subject ,Digestive System Diseases ,Drinking ,Library science ,OVARIAN-CANCER ,Article ,Danish ,Digestive System Disease ,03 medical and health sciences ,Medicine, General & Internal ,General & Internal Medicine ,Journal Article ,Internal Medicine ,Humans ,Mortality ,METAANALYSIS ,Proportional Hazards Models ,Inflammation ,Government ,Science & Technology ,business.industry ,Public health ,Ovarian Neoplasm ,Risk Factor ,Biomarker ,language.human_language ,Cancer registry ,Prospective Studie ,Cerebrovascular Disorders ,RISK-FACTORS ,Proportional Hazards Model ,business ,Welfare ,human activities ,Biomarkers - Abstract
The coordination of EPIC is financially supported by the European Commission (DG-SANCO); and the International Agency for Research on Cancer. The national cohorts are supported by Danish Cancer Society (Denmark); Ligue Contre le Cancer; Institut Gustave Roussy; Mutuelle Generale de l’Education Nationale; and Institut National de la Sante et de la Recherche Medicale (INSERM) (France); Deutsche Krebshilfe, Deutsches Krebsforschungszentrum; and Federal Ministry of Education and Research (Germany); Hellenic Health Foundation; Stavros Niarchos Foundation; and the Hellenic Ministry of Health and Social Solidarity (Greece); Italian Association for Research on Cancer (AIRC); National Research Council; and Associazione Iblea per la Ricerca Epidemiologica (AIRE-ONLUS) Ragusa, Associazione Volontari Italiani Sangu (AVIS) Ragusa, Sicilian Government (Italy); Dutch Ministry of Public Health, Welfare and Sports (VWS); Netherlands Cancer Registry (NKR); LK Research Funds; Dutch Prevention Funds; Dutch ZON (Zorg Onderzoek Nederland); World Cancer Research Fund (WCRF); and Statistics Netherlands (the Netherlands); European Research Council (ERC) (grant number ERC-2009-AdG 232997) and Nordforsk; and Nordic Center of Excellence Programme on Food, Nutrition and Health (Norway); Health Research Fund (FIS); Regional Governments of Andalucia, Asturias, Basque Country, Murcia (No. 6236) and Navarra; and the Centro de Investigacion Biomedica en Red en Epidemiologia y Salud Publica and Instituto de Salud Carlos II (ISCIII RETIC) (RD06/0020) (Spain); Swedish Cancer Society; Swedish Scientific Council; and Regional Government of Skane and Vasterbotten (Sweden); Cancer Research UK; Medical Research Council; Stroke Association; British Heart Foundation; Department of Health; Food Standards Agency; and the Wellcome Trust (UK). Funding for the biomarker measurements in the random sub-cohort was provided by grants to EPIC-InterAct from the European Community Framework Programme 6 and to EPIC-Heart from the Medical Research Council and British Heart Foundation (Joint Award G0800270). We thank Nicola Kerrison (MRC Epidemiology Unit, Cambridge) for managing the data for the InterAct Project. Funding for the InterAct project was provided by the EU FP6 programme (grant number LSHM_CT_2006_037197). The work undertaken by David C Muller was done during the tenure of an IARC, Australia postdoctoral fellowship, supported by the Cancer Council Australia. Domenico Palli was supported by a grant from the Associazione Italiana per la Ricerca sul Cancro-AIRC-Italy. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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- 2018
39. Long-Term Effects of a Primary Weight Gain Prevention Intervention among Healthy Weight Obesity Susceptible Children: Results from the Healthy Start Study.
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Olsen NJ, Larsen SC, and Heitmann BL
- Subjects
- Humans, Child, Male, Female, Child, Preschool, Denmark, Follow-Up Studies, Diet methods, Sleep, Pediatric Obesity prevention & control, Exercise, Body Mass Index, Weight Gain, Primary Prevention methods
- Abstract
Introduction: Primary prevention is a public health strategy that hitherto has not been widely applied in obesity prevention research. The objectives were to examine the long-term effects of the Healthy Start primary obesity prevention study, an intervention conducted among healthy weight children susceptible to develop obesity., Methods: At baseline, children (2-6 years) were allocated to the intervention group (n = 271), the control group (n = 272), or the shadow control group (n = 383). Children in the shadow control group had no contact with project staff during the intervention period (1.3 years on average). The intervention was designed to deliver individually tailored improvements in diet and physical activity habits, optimization of sleep quantity and quality and reduce family stress. After the intervention was completed, height and weight at school entry were obtained from the Danish National Child Health Register when children were around 7 years. The average follow-up time was 2.7 years after baseline. Linear regression analyses on annual changes in BMI (ΔBMI) and BMI z-scores (ΔBMIz) were conducted., Results: At mean 2.7 years after the baseline examination, no differences were observed between the intervention and control group in ΔBMI (β = 0.07 [-0.02; 0.15], p = 0.14) or ΔBMIz (β = 0.04 [-0.02; 0.10], p = 0.19). Likewise, no differences were observed between the intervention and shadow control group in ΔBMI (β = -0.03 [-0.12; 0.06], p = 0.50) or in ΔBMIz (β = -0.02 [-0.08; 0.05], p = 0.62)., Conclusion: We are still in urgent need of more primary overweight prevention interventions to begin to understand how to prevent that healthy weight children develop overweight., (© 2024 The Author(s). Published by S. Karger AG, Basel.)
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- 2024
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40. Does attendance in outdoor kindergartens reduce the use of antibiotics in children?
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Olsen NJ, Larsen SC, Køster-Rasmussen R, Rohde JF, Østergaard JN, Heitmann BL, and Specht IO
- Subjects
- Child, Humans, Educational Status, Drug Prescriptions, Registries, Anti-Bacterial Agents therapeutic use, Schools
- Abstract
Aim: The aim of this study was to determine whether children enrolled in rural outdoor kindergartens had a lower risk of redeeming at least one prescription for antibiotics compared with children enrolled in urban conventional kindergartens, and if type of antibiotics prescribed differed according to kindergarten type., Methods: Two Danish municipalities provided data including civil registration numbers from children enrolled in a rural outdoor kindergarten in 2011-2019, and a subsample of all children enrolled in urban conventional kindergartens in the same period. Civil registration numbers were linked to individual-level information on redeemed prescriptions for antibiotics from the Danish National Prescription Registry. Regression models were performed on 2132 children enrolled in outdoor kindergartens, and 2208 children enrolled in conventional kindergartens., Results: There was no difference between groups in risk of redeeming at least one prescription for all types of antibiotics (adjusted risk ratio: 0.97 [95% confidence intervals 0.93, 1.02, p = 0.26]). Similarly, there were no differences between kindergarten type and risk of redeeming at least one prescription for systemic, narrow-spectrum systemic antibacterial, broad-spectrum systemic antibacterial or topical antibiotics., Conclusion: Compared with children who were enrolled in conventional kindergartens, children who were enrolled in outdoor kindergartens did not have a lower risk of redeeming prescriptions for any type of antibiotics., (© 2023 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.)
- Published
- 2023
- Full Text
- View/download PDF
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