149 results on '"Lasters, Ignace"'
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2. In Silico De-Immunization
3. The 'Dead-End Elimination' Theorem: A New Approach to the Side-Chain Packing Problem
4. Structural Principles of Parallel β -Barrels in Proteins
5. Non-immunized natural human heavy chain CDR3 repertoires allow the isolation of high affinity peptides mimicking a human influenza hemagglutinin epitope
6. Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting
7. Dead-End Based Modeling Tools to Explore the Sequence Space That Is Compatible with a Given Scaffold
8. Arginine 719 in human plasminogen mediates formation of the staphylokinase:plasmin activator complex
9. SABmark—a benchmark for sequence alignment that covers the entire known fold space
10. Align-m—a new algorithm for multiple alignment of highly divergent sequences
11. Crystallography and site-directed mutagenesis of metal binding sites
12. Site-directed mutagenesis of the xylose binding site
13. The dead-end elimination theorem and its use in protein side-chain positioning
14. Arginine residues as stabilizing elements in proteins
15. Reviving old protecting group chemistry for site-selective peptide–protein conjugation
16. Abstract 28: Cell penetrating proteins targeting Mcl-1 inducein vitroandin vivoon-target cancer cell killing of Mcl-1 dependent cell lines
17. Abstract 3850: First-in-class cell-penetrating proteins targeting Mcl-1 induce tumor cell apoptosis and inhibition of tumor growthin vivo
18. Structural basis of IL-23 antagonism by an Alphabody protein scaffold
19. SABmark - a benchmark for sequence alignment that covers the entire known fold space
20. Immunogenicity Assessment of Antibody Therapeutics
21. The Dead-End Elimination Theorem: Mathematical Aspects, Implementation, Optimizations, Evaluation and Performance
22. Flexible Docking of Peptide Ligands to Proteins
23. Species-Specific Determinants in the IgG CH3 Domain Enable Fab-Arm Exchange by Affecting the Noncovalent CH3–CH3 Interaction Strength
24. Quantitative Analysis of the Interaction Strength and Dynamics of Human IgG4 Half Molecules by Native Mass Spectrometry
25. Immunogénicité de protéines d’intérêt thérapeutique
26. NMR structure determination of tick anticoagulant peptide (TAP)
27. Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells
28. Immunogenicity screening in protein drug development
29. Anchor profiles of HLA‐specific peptides: Analysis by a novel affinity scoring method and experimental validation
30. SABmark—a benchmark for sequence alignment that covers the entire known fold space
31. Consistency matrices: Quantified structure alignments for sets of related proteins
32. Comparison of Predicted Scaffold-Compatible Sequence Variation in the Triple-Hairpin Structure of Human Immunodeficiency Virus Type 1 gp41 with Patient Data
33. Fast and accurate side-chain topology and energy refinement (FASTER) as a new method for protein structure optimization
34. Flexible Docking of Peptide Ligands to Proteins.
35. The Dead-End Elimination Theorem:.
36. High-density mutagenesis by combined DNA shuffling and phage display to assign essential amino acid residues in protein-protein interactions: application to study structure-function of plasminogen activation inhibitor 1 (PAI-I)
37. Pharmacokinetic and thrombolytic properties of cysteine-linked polyethylene glycol derivatives of staphylokinase
38. Epitope mapping by negative selection of randomized antigen libraries displayed on filamentous phage 1 1Edited by J. Karn
39. Enzymatic Properties of Phage-Displayed Fragments of Human Plasminogen
40. Computation of the binding of fully flexible peptides to proteins with flexible side chains
41. All in one: a highly detailed rotamer library improves both accuracy and speed in the modelling of sidechains by dead-end elimination
42. Recombinant Staphylokinase Variants With Altered Immunoreactivity
43. Trematode Myoglobins, Functional Molecules with a Distal Tyrosine
44. Strategies in the Design of Inhibitors of Serine Proteases of the Coagulation Cascade - Factor Xa
45. Enhanced dead-end elimination in the search for the global minimum energy conformation of a collection of protein side chains
46. The fuzzy-end elimination theorem: correctly implementing the side chain placement algorithm based on the dead-end elimination theorem
47. Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 2. Site-directed mutagenesis of the xylose binding site
48. Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites
49. Recurrent αβ loop structures in TIM barrel motifs show a distinct pattern of conserved structural features
50. Enhancing the Thermostability of Glucose Isomerase by Protein Engineering
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