1,345 results on '"Laufer, Stefan A."'
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2. Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors
3. The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma
4. Influence of design parameters on sustained drug release properties of 3D-printed theophylline tablets
5. Towards a zero-waste sustainable biorefinery of Codium sp. seaweed: From bioactives application to soil enhancement materials
6. Immune cell targeted fumaric esters support a role of GPR109A as a primary target of monomethyl fumarate in vivo
7. Isostearic acid is an active component of imiquimod formulations used to induce psoriaform disease models
8. First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
9. HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents
10. Ready-to-use nanopore platform for label-free small molecule quantification: Ethanolamine as first example
11. Structural elements that enable specificity for mutant EGFR kinase domains with next-generation small-molecule inhibitors
12. Hemin-induced platelet activation is regulated via ACKR3 chemokine surface receptor - implications for passivation of vulnerable atherosclerotic plaque
13. ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function
14. Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles
15. In vitro and in vivo anti-inflammatory and anticoagulant activities of Myrciaria plinioides D. Legrand ethanol leaf extract
16. Scaffold modified Vemurafenib analogues as highly selective mitogen activated protein kinase kinase 4 (MKK4) inhibitors
17. Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity
18. Synergy of R-(–)carvone and cyclohexenone-based carbasugar precursors with antibiotics to enhance antibiotic potency and inhibit biofilm formation
19. ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury
20. Decisive role of water and protein dynamics in residence time of p38α MAP kinase inhibitors
21. Direct 3D printed biocompatible microfluidics: assessment of human mesenchymal stem cell differentiation and cytotoxic drug screening in a dynamic culture system
22. Discrepancy in interactions and conformational dynamics of pregnane X receptor (PXR) bound to an agonist and a novel competitive antagonist
23. Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy.
24. Rapid Phenotypic Antibiotics Susceptibility Analysis by a 3D Printed Prototype
25. Correction to “Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity”
26. Targeting Lewy body dementia with neflamapimod‐rasagiline hybrids
27. Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS -mutant cancers
28. Journal of Medicinal Chemistry Collection: Drug Discovery in Germany
29. Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity
30. Development of Highly Potent and Selective FGFR4 Inhibitors Based on SNAr Electrophiles
31. Toward more Sustainable Enzyme Reactions: Enhancing Kinetics by Polydimethylacrylamide Implementation
32. Design and synthesis of 1H-pyrazolo[3,4-b]pyridines targeting mitogen-activated protein kinase kinase 4 (MKK4) - A promising target for liver regeneration
33. Combining aptamers and antibodies: Lateral flow quantification for thrombin and interleukin-6 with smartphone readout
34. From off-to on-target: New BRAF-inhibitor-template-derived compounds selectively targeting mitogen activated protein kinase kinase 4 (MKK4)
35. Design and synthesis of novel fluorescently labeled analogs of vemurafenib targeting MKK4
36. Current jakinibs for the treatment of rheumatoid arthritis: a systematic review
37. Selective targeting of the αC and DFG-out pocket in p38 MAPK
38. Identifying representative kinases for inhibitor evaluation via systematic analysis of compound-based target relationships
39. LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer
40. Review of Trials Currently Testing Stem Cells for Treatment of Respiratory Diseases: Facts Known to Date and Possible Applications to COVID-19
41. Promiscuity analysis of a kinase panel screen with designated p38 alpha inhibitors
42. Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors
43. Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency
44. HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents
45. Ready-to-use nanopore platform for label-free small molecule quantification: Ethanolamine as first example
46. Biosynthesis of iron oxide magnetic nanoparticles using clinically isolated Pseudomonas aeruginosa
47. SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions
48. Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation
49. Neuroprotective potential of Myrciaria plinioides D. Legrand extract in an in vitro human neuroblastoma model
50. The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma
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