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1. Spread of SARS-CoV-2 Delta variant infections bearing the S:E484Q and S:T95I mutations in July and August 2021 in France

Author

Brigitte Montes, Mircea T. Sofonea, Gonché Danesh, Laura Verdume, Bénédicte Roquebert, Stéphanie Haim-Boukobza, Edouard Tuaillon, Vincent Foulongne, Samuel Alizon, Sabine Trombert, and Valérie Noël

Subjects
Delta, Whole genome sequencing, Genetics, 2019-20 coronavirus outbreak, Phylogenetic tree, Screening test, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Mutation (genetic algorithm), Biology, Disease cluster
Abstract

Analysing 92,598 variant screening tests performed on SARS-CoV-2 positive samples collected in France between 1 July and 31 August 2021 shows an increase of Kappa-like infections. Full genome sequencing reveals that these correspond to Delta variants bearing the S:E484Q mutation. Most of these sequences belong to a phylogenetic cluster and also bear the S:T95I mutation. Further monitoring is needed to determine if this trend is driven by undocumented superspreading events or an early signal of future viral evolutionary dynamics.

Published
2021

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