Search

Your search keyword '"Laurent Besson-Leaud"' showing total 2 results
Start Over Author "Laurent Besson-Leaud"
2 results on '"Laurent Besson-Leaud"'

1. Lower Respiratory Infections Among Hospitalized Children in New Caledonia: A Pilot Study for the Pneumonia Etiology Research for Child Health Project

Author

David R. Murdoch, Eric D'Ortenzio, Isabelle Missotte, Maria Deloria-Knoll, Virginie Zurawski, Cyril Chevalier, Amanda J. Driscoll, Orin S. Levine, Myrielle Dupont-Rouzeyrol, Olivia O’Connor, Laurent Besson-Leaud, Sylvain Mermond, Fabien Feray, Frederique Fresnais, Vincent Debarnot, Stephanie Noireterre, Andrea DeLuca, Jennifer C. Moïsi, and Bernard Duparc

Subjects
Microbiology (medical), Adolescent, Rhinovirus, Fluorescent Antibody Technique, Supplement Articles, Pilot Projects, Respiratory Syncytial Virus Infections, medicine.disease_cause, Virus, Specimen Handling, Serology, New Caledonia, medicine, Humans, Serologic Tests, Prospective Studies, Respiratory system, Child, Antigens, Viral, Respiratory Tract Infections, Picornaviridae Infections, Bacteria, Respiratory tract infections, business.industry, Sputum, Infant, Bacterial Infections, Pneumonia, medicine.disease, Respiratory Syncytial Viruses, Infectious Diseases, Case-Control Studies, Child, Preschool, Immunology, Etiology, medicine.symptom, business, Child, Hospitalized
Abstract

We conducted a prospective pilot study over a 1-year period in New Caledonia in preparation for the Pneumonia Research for Child Health (PERCH) project. The pathogens associated with hospitalized lower respiratory infections in children were identified through the use of culture of induced sputum and blood, urinary antigen detection, polymerase chain reaction (PCR) on respiratory specimens, and serology on paired sera. Respiratory viruses were detected on respiratory specimens by immunofluorescence and PCR, and by serology on paired sera. Pathogens were detected in 87.9% of the 108 hospitalized cases. Viruses represented 81.6% of the 152 pathogens detected. Respiratory syncytial virus and rhinovirus were the most frequent, accounting for 32.2% and 24.3% of the pathogens identified, respectively. Only 26.3% of 99 induced sputum specimens collected were determined to be of good quality, which may be a consequence of the collection method used.

Published
2012
Full Text
View/download PDF

2. Relationships Between Clinico-Epidemiological Patterns of Invasive Meningococcal Infections and Complement Deficiencies in French South Pacific Islands (New Caledonia)

Author

Isabelle Missotte, Sylvie Laumond-Barny, Martine Noel, Pierre-Emmanuel Spasic, Ann-Claire Gourinat, Yann Barguil, Laurent Besson-Leaud, Cécile Veysseyre Balter, Elodie Descloux, Aurélie de Suremain, Jean-Paul Grangeon, Maguy Daures, Michele John, Olivier Simon, Direction des Affaires sanitaires et sociales de la Nouvelle-Calédonie [Nouméa] (DASS [Nouméa]), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Centre hospitalier territorial Gaston-Bourret [Dumbea] (CHT), Centre hospitalier territorial Gaston-Bourret [Nouméa], Institut Pasteur de Nouvelle-Calédonie, Réseau International des Instituts Pasteur (RIIP), and This work was supported by the New Caledonia Health Department.

Subjects
Male, Bacteremia, Neisseria meningitidis, Serogroup B, MESH: Meningococcal Infections, 0302 clinical medicine, Medical microbiology, MESH: Aged, 80 and over, melanesian population, MESH: Risk Factors, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Child, Epidemiology, Immunology and Allergy, risk factors, 030212 general & internal medicine, Child, MESH: Bacteremia, Aged, 80 and over, MESH: Aged, 0303 health sciences, MESH: Middle Aged, MESH: Meningitis, Meningococcal, Middle Aged, MESH: Infant, 3. Good health, Geography, Invasive meningococcal disease, MESH: Young Adult, Child, Preschool, Female, Neisseria meningitidis, Serogroup Y, Adult, Complement deficiency, medicine.medical_specialty, Adolescent, Immunology, MESH: Complement System Proteins, Meningococcal Infections, Meningitis, Meningococcal, Meningococcal disease, 03 medical and health sciences, Young Adult, Neisseria meningitidis, Serogroup W-135, New Caledonia, MESH: Neisseria meningitidis, Serogroup B, medicine, Humans, Aged, Retrospective Studies, meningococcal disease, MESH: Adolescent, MESH: Humans, 030306 microbiology, MESH: Child, Preschool, Infant, MESH: Adult, MESH: Retrospective Studies, Complement System Proteins, MESH: Neisseria meningitidis, Serogroup W-135, medicine.disease, MESH: New Caledonia, MESH: Male, Metropolitan France, MESH: Neisseria meningitidis, Serogroup Y, MESH: Female, Demography
Abstract

International audience; PurposeInvasive Meningococcal Disease (IMD) is three fold more common in New Caledonia (NC) than in metropolitan France and many IMD cases (35.7 %) are due to Y and W135 serogroups. The purpose of our study was to identify IMD risk factors in NC.MethodsA retrospective study of all IMD cases that occurred in NC between 2005 and 2011 was conducted. Socio-environmental, clinical and biological data were collected. A search for immune deficiency was proposed to all cases. IMD presentation and outcome were compared according to meningoccal serogroups and the complement deficiency status (C-deficiency).ResultsSixty-six sporadic IMD cases (29 B serogroup, 20 Y or W135, 6 C, 1 A, 10 unknown) occurred in 64 patients often

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results