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168 results on '"Lavergne, Rose-Anne"'

1. Characteristics and Prognosis Factors of Pneumocystis jirovecii Pneumonia According to Underlying Disease: A Retrospective Multicenter Study

Author

Raffi, Francois, Boutoille, David, Biron, Charlotte, Lefebvre, Maeva, Gaborit, Benjamin Jean, Le Turnier, Paul, Deschanvres, Colin, Lecomte, Raphael, Chauveau, Marie, Lécuyer, Romain, Asquier-Khati, Antoine, Le Pape, Patrice, Morio, Florent, Lavergne, Rose-Anne, Jeddi, Fakhri, Corvec, Stéphane, Bemer, Pascale, Caillon, Jocelyne, Guillouzouic, Aurélie, Leroy, Anne-Gaëlle, Lakhal, Karim, Cinotti, Raphaël, Roquilly, Antoine, Emmanuel Canet, Jean Reignier, Blanc, François Xavier, Bretonniere, Cédric, Morin, Paul, Camou, Fabrice, Issa, Nahéma, Guisset, Olivier, Mourissoux, Gaelle, Accoceberry, Isabelle, Gabriel, Frederic, Coron, Noémie, Delhaes, Laurence, Imbert, Sébastien, Lefranc, Maxime, Lussac-Sorton, Florian, Rougeron, Amandine, Gousseff, Marie, Crabol, Yoann, Corvaisier, Grégory, Lautredoux, Florent, Cady, Anne, Auger, Myriam, Pouedras, Pascal, Lavergne, Rose-anne, Canet, Emmanuel, Raffi, François, Néel, Antoine, Tessoulin, Benoît, and Gaborit, Benjamin

Published
2024
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2. Plasmodium ovale spp dhfr mutations associated with reduced susceptibility to pyrimethamine in sub-Saharan Africa: a retrospective genetic epidemiology and functional study

Author

Abou-Bacar, Ahmed, Agnamey, Patrice, Ait-Ammar, Nawel, Angoulvant, Adela, Argy, Nicolas, Azjenberg, Daniel, Basmaciyan, Louise, Bastien, Patrick, Belaz, Sorya, Belkadi, Ghania, Bellanger, Anne-Pauline, Bemba, Dieudonné, Berry, Antoine, Botterel, François, Bouden, Vincent, Bougnoux, Marie-Elisabeth, Bouzayene, Azza, Bret, Laurent, Bretagne, Stéphane, Brumpt, Caren, Buret, Bernadette, Caraux-Paz, Pauline, Cheruiyot, Agnes, Chlilek, Alexandre, Clauser, Sylvain, Cojean, Sandrine, Cuisenier, Bernadette, Dahane, Naima, Dannaoui, Eric, Dard, Céline, Dardé, Marie-Laure, de Gentile, Ludovic, Debourgogne, Anne, Dechavanne, Célia, Delaunay, Pascal, Delaval, Anne, Deleplancque, Anne-Sophie, Desoubeaux, Guillaume, Desuremain, Nathalie, Develoux, Michel, Djènontin, Armel, Dossou, Yannelle, Durand, Rémy, Durieux, Marie-Fleur, Dutoit, Emmanuel, Eloy, Odile, Fenneteau, Odile, Fievet, Nadine, Gargala, Gilles, Garnaud, Cécile, Gay-Andrieu, Françoise, Godineau, Nadine, Gravet, Alain, Guennouni, Nadia, Guinard, Jérôme, Hamane, Samia, Huguenin, Antoine, Jumah, Jacqueline, L'Ollivier, Coralie, Landraud, Luce, Larréché, Sébastien, Lavergne, Rose-Anne, Le Govic, Yohann, Lohmann, Caroline, Machouart, Marie-Claire, Marteau, Anthony, Massougbodji, Achille, Mazars, Edith, Mechain, Matthieu, Mendes Moreira, Ana, Merat, Célia, Millon, Laurence, Mombo-Ngoma, Ghyslain, Morelle, Christelle, Morio, Florent, Mwakio, Edwin, Nabias, René, Nourrisson, Céline, Opot, Benjamin, Okhot, Raphael, Patoz, Pierre, Penn, Pascal, Perraud-Cateau, Estelle, Pihet, Marc, Pilo, Jean-Etienne, Pistone, Thierry, Poilane, Isabelle, Pomares, Christelle, Pons, Denis, Pougnet, Laurence, Pull, Lauren, Quinio, Dorothée, Raffenot, Didier, Rapp, Christophe, Receveur, Marie-Catherine, Roosen, Gabrielle, Sarrasin, Véronique, Sasso, Milene, Savini, Hélène, Senghor, Yaye, Silva, Muriel, Simon, Fabrice, Siriez, Jean-Yves, Sossou, Darius, Thellier, Marc, Thouvenin, Maxime, Toubas, Dominique, Tournus, Cécile, Touroult-Jupin, Pauline, Veletzky, Luzia, Vianou, Bertin, Zaffaroullah, Rizwana, Zoleko-Manego, Rella, Joste, Valentin, Coppée, Romain, Bailly, Justine, Rakotoarivony, Yann, Toko Tchokoteu, Francine Ghislaine, Achache, Shany, Pradines, Bruno, Cottrell, Gilles, Ariey, Frédéric, Khim, Nimol, Popovici, Jean, Mita, Toshihiro, Groger, Mirjam, Ramharter, Michael, Egbo, Timothy, Juma, Dennis W, Akala, Hoseah, Houzé, Sandrine, and Clain, Jérôme

Published
2024
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5. Should We Reconsider PneumocystisPneumonia Presentation and Treatment According to Its Underlying Disease?

Author

Gaborit, Benjamin, Lécuyer, Romain, Issa, Nahéma, Camou, Fabrice, Lavergne, Rose-anne, Gabriel, Frederic, Morio, Florent, Canet, Emmanuel, Raffi, François, Boutoille, David, Cady, Anne, Gousseff, Marie, Crabol, Yoann, Néel, Antoine, Tessoulin, Benoît, Raffi, Francois, Boutoille, David, Biron, Charlotte, Lefebvre, Maeva, Gaborit, Benjamin Jean, Le Turnier, Paul, Deschanvres, Colin, Lecomte, Raphael, Chauveau, Marie, Lécuyer, Romain, Asquier-Khati, Antoine, Pineau, Valentin, Prime, Marie, Delaunay, Clarisse, Essid, Hakim, Le Pape, Patrice, Morio, Florent, Lavergne, Rose-Anne, Jeddi, Fakhri, Corvec, Stéphane, Bemer, Pascale, Caillon, Jocelyne, Guillouzouic, Aurélie, Leroy, Anne-Gaëlle, Lakhal, Karim, Cinotti, Raphaël, Roquilly, Antoine, Jean Reignier, Mickael Vourc’h;, Canet, Emmanuel, Blanc, François Xavier, Bretonniere, Cédric, Morin, Jean, Le Blanc, Camille, Alami, Hakim, Camou, Fabrice, Issa, Nahéma, Guisset, Olivier, Mourissoux, Gaelle, Accoceberry, Isabelle, Gabriel, Frederic, Coron, Noémie, Delhaes, Laurence, Imbert, Sébastien, Lefranc, Maxime, Lussac-Sorton, Florian, Rougeron, Amandine, Gousseff, Marie, Crabol, Yoann, Corvaisier, Grégory, Lautredoux, Florent, Anne Cady, Romain Lécuyerand, Auger, Myriam, and Pouedras, Pascal

Published
2024
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7. Should We Reconsider Pneumocystis Pneumonia Presentation and Treatment According to Its Underlying Disease?: An Unsupervised Cluster Analysis of a Retrospective Multicenter Study

Author

Raffi, Francois, Boutoille, David, Biron, Charlotte, Lefebvre, Maeva, Gaborit, Benjamin Jean, Le Turnier, Paul, Deschanvres, Colin, Lecomte, Raphael, Chauveau, Marie, Lécuyer, Romain, Asquier-Khati, Antoine, Pineau, Valentin, Prime, Marie, Delaunay, Clarisse, Essid, Hakim, Le Pape, Patrice, Morio, Florent, Lavergne, Rose-Anne, Jeddi, Fakhri, Corvec, Stéphane, Bemer, Pascale, Caillon, Jocelyne, Guillouzouic, Aurélie, Leroy, Anne-Gaëlle, Lakhal, Karim, Cinotti, Raphaël, Roquilly, Antoine, Jean Reignier, Mickael Vourc’h, Canet, Emmanuel, Blanc, François Xavier, Bretonniere, Cédric, Morin, Jean, Le Blanc, Camille, Alami, Hakim, Camou, Fabrice, Issa, Nahéma, Guisset, Olivier, Mourissoux, Gaelle, Accoceberry, Isabelle, Gabriel, Frederic, Coron, Noémie, Delhaes, Laurence, Imbert, Sébastien, Lefranc, Maxime, Lussac-Sorton, Florian, Rougeron, Amandine, Gousseff, Marie, Crabol, Yoann, Corvaisier, Grégory, Lautredoux, Florent, Anne Cady, Romain Lécuyerand, Auger, Myriam, Pouedras, Pascal, Gaborit, Benjamin, Lavergne, Rose-anne, Raffi, François, Cady, Anne, Néel, Antoine, and Tessoulin, Benoît

Published
2024
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8. Should We Reconsider Pneumocystis Pneumonia Presentation and Treatment According to Its Underlying Disease?: An Unsupervised Cluster Analysis of a Retrospective Multicenter Study.

Author

Gaborit, Benjamin, Lécuyer, Romain, Issa, Nahéma, Camou, Fabrice, Lavergne, Rose-anne, Gabriel, Frederic, Morio, Florent, Canet, Emmanuel, Raffi, François, Boutoille, David, Cady, Anne, Gousseff, Marie, Crabol, Yoann, Néel, Antoine, and Tessoulin, Benoît

Subjects
PNEUMOCYSTIS pneumonia, CLUSTER analysis (Statistics), RETROSPECTIVE studies, THERAPEUTICS
Published
2024
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9. Plasmodium ovale spp dhfr mutations associated with reduced susceptibility to pyrimethamine in sub-Saharan Africa: a retrospective genetic epidemiology and functional study

Author

Joste, Valentin, primary, Coppée, Romain, additional, Bailly, Justine, additional, Rakotoarivony, Yann, additional, Toko Tchokoteu, Francine Ghislaine, additional, Achache, Shany, additional, Pradines, Bruno, additional, Cottrell, Gilles, additional, Ariey, Frédéric, additional, Khim, Nimol, additional, Popovici, Jean, additional, Mita, Toshihiro, additional, Groger, Mirjam, additional, Ramharter, Michael, additional, Egbo, Timothy, additional, Juma, Dennis W, additional, Akala, Hoseah, additional, Houzé, Sandrine, additional, Clain, Jérôme, additional, Abou-Bacar, Ahmed, additional, Agnamey, Patrice, additional, Ait-Ammar, Nawel, additional, Angoulvant, Adela, additional, Argy, Nicolas, additional, Azjenberg, Daniel, additional, Basmaciyan, Louise, additional, Bastien, Patrick, additional, Belaz, Sorya, additional, Belkadi, Ghania, additional, Bellanger, Anne-Pauline, additional, Bemba, Dieudonné, additional, Berry, Antoine, additional, Botterel, François, additional, Bouden, Vincent, additional, Bougnoux, Marie-Elisabeth, additional, Bouzayene, Azza, additional, Bret, Laurent, additional, Bretagne, Stéphane, additional, Brumpt, Caren, additional, Buret, Bernadette, additional, Caraux-Paz, Pauline, additional, Cheruiyot, Agnes, additional, Chlilek, Alexandre, additional, Clauser, Sylvain, additional, Cojean, Sandrine, additional, Cuisenier, Bernadette, additional, Dahane, Naima, additional, Dannaoui, Eric, additional, Dard, Céline, additional, Dardé, Marie-Laure, additional, de Gentile, Ludovic, additional, Debourgogne, Anne, additional, Dechavanne, Célia, additional, Delaunay, Pascal, additional, Delaval, Anne, additional, Deleplancque, Anne-Sophie, additional, Desoubeaux, Guillaume, additional, Desuremain, Nathalie, additional, Develoux, Michel, additional, Djènontin, Armel, additional, Dossou, Yannelle, additional, Durand, Rémy, additional, Durieux, Marie-Fleur, additional, Dutoit, Emmanuel, additional, Eloy, Odile, additional, Fenneteau, Odile, additional, Fievet, Nadine, additional, Gargala, Gilles, additional, Garnaud, Cécile, additional, Gay-Andrieu, Françoise, additional, Godineau, Nadine, additional, Gravet, Alain, additional, Guennouni, Nadia, additional, Guinard, Jérôme, additional, Hamane, Samia, additional, Huguenin, Antoine, additional, Jumah, Jacqueline, additional, L'Ollivier, Coralie, additional, Landraud, Luce, additional, Larréché, Sébastien, additional, Lavergne, Rose-Anne, additional, Le Govic, Yohann, additional, Lohmann, Caroline, additional, Machouart, Marie-Claire, additional, Marteau, Anthony, additional, Massougbodji, Achille, additional, Mazars, Edith, additional, Mechain, Matthieu, additional, Mendes Moreira, Ana, additional, Merat, Célia, additional, Millon, Laurence, additional, Mombo-Ngoma, Ghyslain, additional, Morelle, Christelle, additional, Morio, Florent, additional, Mwakio, Edwin, additional, Nabias, René, additional, Nourrisson, Céline, additional, Opot, Benjamin, additional, Okhot, Raphael, additional, Patoz, Pierre, additional, Penn, Pascal, additional, Perraud-Cateau, Estelle, additional, Pihet, Marc, additional, Pilo, Jean-Etienne, additional, Pistone, Thierry, additional, Poilane, Isabelle, additional, Pomares, Christelle, additional, Pons, Denis, additional, Pougnet, Laurence, additional, Pull, Lauren, additional, Quinio, Dorothée, additional, Raffenot, Didier, additional, Rapp, Christophe, additional, Receveur, Marie-Catherine, additional, Roosen, Gabrielle, additional, Sarrasin, Véronique, additional, Sasso, Milene, additional, Savini, Hélène, additional, Senghor, Yaye, additional, Silva, Muriel, additional, Simon, Fabrice, additional, Siriez, Jean-Yves, additional, Sossou, Darius, additional, Thellier, Marc, additional, Thouvenin, Maxime, additional, Toubas, Dominique, additional, Tournus, Cécile, additional, Touroult-Jupin, Pauline, additional, Veletzky, Luzia, additional, Vianou, Bertin, additional, Zaffaroullah, Rizwana, additional, and Zoleko-Manego, Rella, additional

Published
2024
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10. Multicenter evaluation of the Toxoplasma gondii Real-TM (Sacace) kit performance for the molecular diagnosis of toxoplasmosis

Author

Guitard, Juliette, primary, Brenier-Pinchart, Marie-Pierre, additional, Varlet-Marie, Emmanuelle, additional, Dalle, Frédéric, additional, Rouges, Celia, additional, Argy, Nicolas, additional, Bonhomme, Julie, additional, Capitaine, Agathe, additional, Guégan, Hélène, additional, Lavergne, Rose-Anne, additional, Dardé, Marie-Laure, additional, Pelloux, Hervé, additional, Robert-Gangneux, Florence, additional, Yera, Hélène, additional, and Sterkers, Yvon, additional

Published
2024
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13. The Novodiag® Stool parasites assay, an innovative high-plex technique for fast detection of protozoa, helminths and microsporidia in stool samples: a retrospective and prospective study

Author

Hartuis Sophie, Lavergne Rose-Anne, Nourrisson Céline, Verweij Jaco, Desoubeaux Guillaume, Lussac-Sorton Florian, Lemoine Jean-Philippe, Cateau Estelle, Jeddi Fakhri, Poirier Philippe, Le Pape Patrice, and Morio Florent

Subjects
stool, gastrointestinal parasites, microscopy, novodiag® stool parasites, high-plex detection, prospective study, comparative evaluation, Infectious and parasitic diseases, RC109-216
Abstract

Objectives: We provide the first evaluation of the CE-IVD marked Novodiag® stool parasites assay (NVD), allowing rapid and high-plex detection of 26 distinct targets, encompassing protozoans, helminths and microsporidia in stool samples. Methods: A total of 254 samples (n = 205 patients) were prospectively processed by the NVD and our routine procedure (RP). Performances of the NVD were compared with RP. Samples only positive by the NVD assay were investigated by external PCR assays. Sensitivity and specificity (Se/Sp) and time from sample receipt to results were determined for each method. The NVD was also evaluated against 77 additional samples positive for a wide range of parasites. Results: Overall positivity rate was 16.9% for RP compared with 34% using the NVD assay, and 164 samples (66%) were negative by both methods. Only 30 positive samples (12%) showed full concordance between RP and NVD. Fifty-three discordant samples were sent for external investigations. Except for Giardia intestinalis and Trichuris spp., higher Se was observed for the NVD assay for Blastocystis spp. (100% vs. 63%), Dientamoeba fragilis (100% vs. 0%), Schistosoma spp. (100% vs. 17%), and Enterobius vermicularis (100% vs. 67%) but roughly similar to RP for the remaining parasites tested. False-positive results were identified for Blastocystis spp., G. intestinalis, and Trichuris spp. using the NVD assay. The NVD mostly provides a diagnosis on the day of sample receipt compared with a mean of three days with RP. Conclusions: Besides some limitations, the NVD is a new diagnostic strategy allowing rapid and high-plex detection of gastrointestinal parasites from unpreserved stools.

Published
2022
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14. Characteristics and Prognosis Factors of Pneumocystis jirovecii Pneumonia According to Underlying Disease: A Retrospective Multicenter Study.

Author

Lécuyer, Romain, Issa, Nahéma, Camou, Fabrice, Lavergne, Rose-anne, Gabriel, Frederic, Morio, Florent, Canet, Emmanuel, Raffi, François, Boutoille, David, Cady, Anne, Gousseff, Marie, Crabol, Yoann, Néel, Antoine, Tessoulin, Benoît, and Gaborit, Benjamin

Subjects
PNEUMOCYSTIS pneumonia, PNEUMOCYSTIS jiroveci, PROGNOSIS, SYMPTOMS, RETROSPECTIVE studies
Abstract

Pneumocystis jirovecii pneumonia (PcP) remains associated with high rates of mortality, and the impact of immunocompromising underlying disease on the clinical presentation, severity, and mortality of PcP has not been adequately evaluated. Does the underlying disease and immunosuppression causing PcP impact the outcome and clinical presentation of the disease? In this multicenter retrospective observational study, conducted from January 2011 to December 2021, all consecutive patients admitted with a proven or probable diagnosis of PcP according to the European Organisation for Research and Treatment of Cancer consensus definitions were included to assess the epidemiology and impact of underlying immunosuppressive diseases on overall and 90-day mortality. Overall, 481 patients were included in the study; 180 (37.4%) were defined as proven PcP and 301 (62.6%) were defined as probable PcP. Patients with immune-mediated inflammatory diseases (IMIDs) or solid tumors had a statistically poorer prognosis than other patients with PcP at day 90. In multivariate analysis, among the HIV-negative population, solid tumor underlying disease (OR, 5.47; 95% CI, 2.16-14.1; P <.001), IMIDs (OR, 2.19; 95% CI, 1.05-4.60; P =.037), long-term corticosteroid exposure (OR, 2.07; 95% CI, 1.03-4.31; P =.045), cysts in sputum/BAL smears (OR, 1.92; 95% CI, 1.02-3.62; P =.043), and SOFA score at admission (OR, 1.58; 95% CI, 1.39-1.82; P <.001) were independently associated with 90-day mortality. Prior corticotherapy was the only immunosuppressant associated with 90-day mortality (OR, 1.67; 95% CI, 1.03-2.71; P =.035), especially for a prednisone daily dose ≥ 10 mg (OR, 1.80; 95% CI, 1.14-2.85; P =.010). Among patients who were HIV-negative, long-term corticosteroid prior to PcP diagnosis was independently associated with increased 90-day mortality, specifically in patients with IMIDs. These results highlight both the needs for PcP prophylaxis in patients with IMIDs and to early consider PcP curative treatment in severe pneumonia among patients with IMIDs. [Display omitted] [ABSTRACT FROM AUTHOR]

Published
2024
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16. Outcome and prognostic factors of Pneumocystis jirovecii pneumonia in immunocompromised adults: a prospective observational study

Author

Gaborit, Benjamin Jean, Tessoulin, Benoit, Lavergne, Rose-Anne, Morio, Florent, Sagan, Christine, Canet, Emmanuel, Lecomte, Raphael, Leturnier, Paul, Deschanvres, Colin, Khatchatourian, Lydie, Asseray, Nathalie, Garret, Charlotte, Vourch, Michael, Marest, Delphine, Raffi, François, Boutoille, David, and Reignier, Jean

Published
2019
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17. Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples

Author

MMB, MMB Medische Staf, Nourrisson, Céline, Moniot, Maxime, Lavergne, Rose Anne, Robert, Estelle, Bonnin, Virginie, Hagen, Ferry, Grenouillet, Frédéric, Cafarchia, Claudia, Butler, Geraldine, Cassaing, Sophie, Sabou, Marcela, Le Pape, Patrice, Poirier, Philippe, Morio, Florent, MMB, MMB Medische Staf, Nourrisson, Céline, Moniot, Maxime, Lavergne, Rose Anne, Robert, Estelle, Bonnin, Virginie, Hagen, Ferry, Grenouillet, Frédéric, Cafarchia, Claudia, Butler, Geraldine, Cassaing, Sophie, Sabou, Marcela, Le Pape, Patrice, Poirier, Philippe, and Morio, Florent

Published
2023

19. Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples

Author

Nourrisson, Céline, primary, Moniot, Maxime, additional, Lavergne, Rose-Anne, additional, Robert, Estelle, additional, Bonnin, Virginie, additional, Hagen, Ferry, additional, Grenouillet, Frédéric, additional, Cafarchia, Claudia, additional, Butler, Geraldine, additional, Cassaing, Sophie, additional, Sabou, Marcela, additional, Le Pape, Patrice, additional, Poirier, Philippe, additional, and Morio, Florent, additional

Published
2023
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21. Serological diagnosis of Toxoplasma gondii: analysis of false-positive IgG results and implications

Author

Simon Loïc, Fillaux Judith, Guigon Aurélie, Lavergne Rose-Anne, Villard Odile, Villena Isabelle, Marty Pierre, and Pomares Christelle

Subjects
toxoplasma gondii, igg, false-positive, serology, architect, toxoplasmosis, Infectious and parasitic diseases, RC109-216
Abstract

Background: Primary infection by Toxoplasma gondii in pregnant women can result in serious outcomes for the foetus. A false-positive IgG result during pregnancy can lead to a misdiagnosis of past infection and to stopping preventive measures. We collected 189 sera with positive Architect® Toxo IgG assay (Abbott Laboratories) and negative IgG results with at least two other serological tests, in order to find an explanation for the suspected false-positive IgG results. We used the recomLine Toxoplasma IgG® immunoblot (Mikrogen Diagnostik) to search for specific antigenic reactivities of the sera, and the LDBio Toxo II IgG® immunoblot (LDBio Diagnostics) as a confirmatory test. Results: The bands GRA8 and/or GRA7 were positive for 148 samples (78.3%). GRA8 was the most frequent band, appearing in 133 patterns (70.4%), whereas GRA7 was present for 49 samples (25.9%). Of the 81 samples tested with LDBio®, 23 (28.4%) turned out to be positive. Of the 58 negative LDBio® tests (71.6%) (real false-positive Architect® IgG), 23 samples (39.6%) did not show either a GRA8 or p30 band by recomLine®. Their false positivity with Architect® remains unexplained since Abbott uses these two recombinant antigens for their assay. Conclusions: The Architect® IgG false positivity for T. gondii seems to be due to reactivity against GRA8 for the majority of the sera and GRA7 to a lesser extent. The hypothesis of past contact with parasites genetically close to T. gondii such as Hammondia hammondi or Neospora caninum seems promising and should be assessed further.

Published
2020
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24. Prenatal therapy with pyrimethamine + sulfadiazine vs spiramycin to reduce placental transmission of toxoplasmosis: a multicenter, randomized trial

Author

Laurichesse-Delmas, Hélène, Pons, Denis, Nourrisson, C., Winer, Norbert, Lavergne, Rose-Anne, Berrebi, Alain, Fillaux, Judith, Assouline, Corinne, Mesnard, Louis, Villena, Isabelle, Bory, Jean-Paul, Le Bouar, Gwenaëlle, Robert-Gangneux, Florence, d’Ercole, Claude, L’Ollivier, Coralie, Bretelle, Florence, Guidicelli, Béatrice, Garcia, Patricia, Cordier, Anne-Gaelle, Benachi, Alexandra, Vauloup-Fellous, Christelle, Letamendia, Emmanuelle, Ville, Yves, Bougnoux, Marie-Elisabeth, Perrotin, Franck, Van Langendonck, Nathalie, Potin, Jérôme, Marty, Pierre, Pomarès, Christelle, Trastour, Cynthia, Houfflin-Debarge, Véronique, Deleplancque, Anne Sophie, Kieffer, François, Jouannic, Jean-Marie, Costa, Jean-Marc, Chève, Marie-Thérèse, Col, Jean-Yves, Biquard, Florence, Cimon, Bernard, Sterkers, Y., Lachaud, Laurence, Burlet, Gilles, Maréchaud, Martine, Perraud, Estelle, Grébille, Anne-Gaelle, Valentin, Morgane, Houzé, Sandrine, Omnès, Sophie, Chitrit, Yvon, Boissinot, Christine, Yéra, Hélène, Anselem, Olivia, Tsatsaris, Vassilis, Sénat, Marie-Victoire, Fuchs, Florent, Angoulvant, Adela, Muszynski, Charles, Totet, Anne, Noël, Catherine, Bidat, Laurent, Barjat, Tiphaine, Flori, Pierre, Pelloux, Hervé, Brenier-Pinchart, Marie-Pierre, Thong-Vanh, Catherine, Mandelbrot, Laurent, Floch, Corinne, Carbillon, Lionel, Lachassine, Eric, Ricbourg, Aude, Paris, Luc, Dommergues, Marc, Rousseau, Thierry, Dalle, Frederic, Dardé, Marie Laure, Aubard, Véronique, Olivier, Camille, Verspyk, Eric, Favennec, Loic, Sitta, Rémi, Cordier, Anne-Gaëlle, and Thiébaut, Rodolphe

Published
2018
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25. P468 Aspergillosis in a colony of Humboldt penguins (Spheniscus humboldti) under managed care: a clinical and environmental investigation in a French zoological park

Author

Perraud-Cateau, Estelle, primary, Leclerc, Antoine, additional, Cartier, Noémie, additional, Valsechi, Isabel, additional, Bailly, Eric, additional, Senechal, Ronan Le, additional, Becerra, Margaux, additional, Gallou, Brice Le, additional, Lavergne, Rose-Anne, additional, Chesnay, Adélaïde, additional, Robin, Jean-Patrice, additional, Cray, Carolyn, additional, Goddard, Nicolas, additional, Thorel, Milan, additional, Guillot, Jacques, additional, Mulot, Baptiste, additional, and Desoubeaux, Guillaume, additional

Published
2022
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26. Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples

Author

Nourrisson, Céline, Moniot, Maxime, Lavergne, Rose-Anne, Robert, Estelle, Bonnin, Virginie, Hagen, Ferry, Grenouillet, Frédéric, Cafarchia, Claudia, Butler, Geraldine, Cassaing, Sophie, Sabou, Marcela, Le Pape, Patrice, Poirier, Philippe, Morio, Florent, Nourrisson, Céline, Moniot, Maxime, Lavergne, Rose-Anne, Robert, Estelle, Bonnin, Virginie, Hagen, Ferry, Grenouillet, Frédéric, Cafarchia, Claudia, Butler, Geraldine, Cassaing, Sophie, Sabou, Marcela, Le Pape, Patrice, Poirier, Philippe, and Morio, Florent

Published
2022

27. Collateral consequences of agricultural fungicides on pathogenic yeasts:A One Health perspective to tackle azole resistance

Author

Castelo-Branco, Débora, Lockhart, Shawn R., Chen, Yee Chun, Santos, Daniel Assis, Hagen, Ferry, Hawkins, Nichola Jane, Lavergne, Rose Anne, Meis, Jacques F., Le Pape, Patrice, Rocha, Marcos Fabio Gadelha, Sidrim, José Julio Costa, Arendrup, Maiken, Morio, Florent, Castelo-Branco, Débora, Lockhart, Shawn R., Chen, Yee Chun, Santos, Daniel Assis, Hagen, Ferry, Hawkins, Nichola Jane, Lavergne, Rose Anne, Meis, Jacques F., Le Pape, Patrice, Rocha, Marcos Fabio Gadelha, Sidrim, José Julio Costa, Arendrup, Maiken, and Morio, Florent

Abstract

Candida and Cryptococcus affect millions of people yearly, being responsible for a wide array of clinical presentations, including life-threatening diseases. Interestingly, most human pathogenic yeasts are not restricted to the clinical setting, as they are also ubiquitous in the environment. Recent studies raise concern regarding the potential impact of agricultural use of azoles on resistance to medical antifungals in yeasts, as previously outlined with Aspergillus fumigatus. Thus, we undertook a narrative review of the literature and provide lines of evidence suggesting that an alternative, environmental route of azole resistance, may develop in pathogenic yeasts, in addition to patient route. However, it warrants sound evidence to support that pathogenic yeasts cross border between plants, animals and humans and that environmental reservoirs may contribute to azole resistance in Candida or other yeasts for humans. As these possibilities could concern public health, we propose a road map for future studies under the One Health perspective.

Published
2022

28. Aspergillosis in a colony of Humboldt penguins (Spheniscus humboldti) under managed care: a clinical and environmental investigation in a French zoological park

Author

Cateau, Estelle, primary, Leclerc, Antoine, additional, Cartier, Noémie, additional, Valsecchi, Isabel, additional, Bailly, Éric, additional, Le Senechal, Ronan, additional, Becerra, Margaux, additional, Le Gallou, Brice, additional, Lavergne, Rose-Anne, additional, Chesnay, Adélaïde, additional, Robin, Jean-Patrice, additional, Cray, Carolyn, additional, Goddard, Nicolas, additional, Thorel, Milan, additional, Guillot, Jacques, additional, Mulot, Baptiste, additional, and Desoubeaux, Guillaume, additional

Published
2022
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29. Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France

Author

Coppée, Romain, primary, Bailly, Justine, additional, Sarrasin, Véronique, additional, Vianou, Bertin, additional, Zinsou, Boris Enock, additional, Mazars, Edith, additional, Georges, Hugues, additional, Hamane, Samia, additional, Lavergne, Rose Anne, additional, Dannaoui, Eric, additional, Balikagala, Betty, additional, Fukuda, Naoyuki, additional, Odongo-Aginya, Emmanuel I, additional, Mita, Toshihiro, additional, Houzé, Sandrine, additional, and Clain, Jérôme, additional

Published
2022
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30. Impact of TR34/L98H, TR46/Y121F/T289A and TR53 Alterations in Azole-Resistant Aspergillus fumigatus on Sterol Composition and Modifications after In Vitro Exposure to Itraconazole and Voriconazole

Author

Lavergne, Rose-Anne, primary, Albassier, Marjorie, additional, Hardouin, Jean-Benoît, additional, Alvarez-Moreno, Carlos, additional, Pagniez, Fabrice, additional, Morio, Florent, additional, Le Pape, Patrice, additional, and Ourliac-Garnier, Isabelle, additional

Published
2022
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31. Epidemiological and clinical study of microsporidiosis in French kidney transplant recipients from 2005 to 2019: TRANS‐SPORE registry

Author

Dumond, Clément, Aulagnon, Florence, Etienne, Isabelle, Heng, Anne‐Elisabeth, Bougnoux, Marie‐Elisabeth, Favennec, Loic, Kamar, Nassim, Iriart, Xavier, Pereira, Bruno, Büchler, Mathias, Desoubeaux, Guillaume, Kaminski, Hannah, Lussac‐Sorton, Florian, Gargala, Gilles, Anglicheau, Dany, Poirier, Philippe, Scemla, Anne, Garrouste, Cyril, Labbe, Franck, Damiani, Céline, Le Govic, Yohann, Totet, Anne, De Gentile, Ludovic, Lemoine, Jean‐Philippe, Bellanger, Anne Pauline, Accoceberry, Isabelle, Delhaes, Laurence, Gabriel, Frédéric, Millet, Pascal, Le Gal, Solène, Nevez, Gilles, Bonhomme, Julie, Capitaine, Agathe, Demar, Magalie, Moniot, Maxime, Nourrisson, Céline, Angebault, Cécile, Botterel, Françoise, Foulet, Françoise, Basmaciyan, Louise, Dalle, Frédéric, Valot, Stéphane, Desbois‐Nogard, Nicole, Robert, Gladys, Deleplancque, Anne‐Sophie, Frealle, Emilie, Leroy, Jordan, Ajzenberg, Daniel, Durieux, Marie‐Fleur, Chapey‐Picq, Emmanuelle, Dupont, Damien, Menotti, Jean, Rabodonirina, Meja, Lollivier, Coralie, Bastien, Patrick, Debourgogne, Anne, Machouart, Marie, Lavergne, Rose‐Anne, Morio, Florent, Delaunay, Pascal, Pomares, Christelle, Simon, Loïc, Sasso, Milène, Argy, Nicolas, Houze, Sandrine, Yera, Hélène, Dannaoui, Eric, Sitterle, Emilie, Kapel, Nathalie, Tantaoui, Ilhame, Thellier, Marc, Belkadi, Ghania Belkacem, Moreno‐Sabater, Alicia, Hamane, Samia, Nicolas, Muriel, Perraud, Estelle, Chemla, Cathy, Villena, Isabelle, Autier, Brice, Costa, Damien, Flori, Pierre, Brunet, Julie, BERRY, Antoine, Chesnay, Adélaïde, Artur, Fabienne, Verdurme, Laura, Foulquier, Jean‐Baptiste, Prigent, Gwenole, Chatelain, Rémi, Lesthelle, Sophie, Groupe d'Étude des Interactions Hôte-Pathogène (GEIHP), Université d'Angers (UA), SFR UA 4208 Interactions Cellulaires et Applications Thérapeutiques (ICAT), Laboratoire de Parasitologie et Mycologiede [CHRU Brest], Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), CHU Clermont-Ferrand, CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Rouen, Normandie Université (NU), Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), CHU Bordeaux [Bordeaux], Infection Inflammation et Interaction Hôtes Pathogènes [CHU Clermont-Ferrand] (3IHP ), Direction de la recherche clinique et de l’innovation [CHU Clermont-Ferrand] (DRCI), CHU Clermont-Ferrand-CHU Clermont-Ferrand, Université Clermont Auvergne (UCA), Centre Hospitalier Universitaire de Reims (CHU Reims), Epidémiosurveillance de protozooses à transmission alimentaire et vectorielle (ESCAPE), Université de Reims Champagne-Ardenne (URCA)-Université de Rouen Normandie (UNIROUEN), and Normandie Université (NU)-Normandie Université (NU)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)

Subjects
Male, medicine.medical_specialty, Opportunistic infection, [SDV]Life Sciences [q-bio], 030230 surgery, Microsporidiosis, Gastroenterology, Albendazole, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, parasitic diseases, medicine, Humans, Enterocytozoon bieneusi, Fumagillin, Registries, Kidney transplantation, ComputingMilieux_MISCELLANEOUS, Aged, 0303 health sciences, Transplantation, biology, 030306 microbiology, business.industry, Enterocytozoon, Middle Aged, Spores, Fungal, fumagillin, medicine.disease, biology.organism_classification, Kidney Transplantation, 3. Good health, immunosuppressive regimen, Diarrhea, Infectious Diseases, medicine.symptom, business, medicine.drug
Abstract

Introduction Microsporidiosis is an emerging opportunistic infection in renal transplantation (RT) recipients. We aimed to describe its clinical presentation and treatment. Materials and methods We collected microsporidiosis cases identified in RT recipients between 2005 and 2019 in six French centers from the Crystal, Divat and Astre prospective databases. Results We report 68 RT recipients with intestinal microsporidiosis; the patients were predominantly male (61.8%), with a median age of 58 (46-69) years. Infection occurred at a median time of 3 (0.8-6.8) years posttransplant. Only Enterocytozoon bieneusi was found. Microsporidiosis manifested as diarrhea (98.5% of patients) with weight loss (72.1%) and acute renal injury (57.4%) without inflammatory biological parameters. The therapeutic approaches were no treatment (N = 9), reduction of the immunosuppressive regimen (∆IS) (N = 22), fumagillin alone (N = 9), fumagillin and ∆IS (N = 19), and albendazole or nitazoxanide and ∆IS (N = 9). Overall clinical remission was observed in 60 patients (88.2%). We observed no acute kidney rejection, renal transplant failure or death within 6 months after microsporidiosis. Conclusion E. bieneusi is an underestimated opportunistic pathogen in RT recipients, and infection with E. bieneusi leads to diarrhea with important dehydration and acute renal injury. The treatment is based on the reduction of the immunosuppressive regimen and the administration of fumagillin if available. This article is protected by copyright. All rights reserved.

Published
2021
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32. In vitro antifungal effect of a plant-based product, CIN-102, on antifungal resistant filamentous fungi and their biofilms

Author

D'Agostino, Maurine, Lemmet, Thomas, Dufay, Claire, Luc, Amandine, Frippiat, Jean Pol, Machouart, Marie, Debourgogne, Anne, Tesse, Nicolas, Lavergne, Rose Anne, Le Pape, Patrice, Stress, Immunité, Pathogènes (SIMPA), Université de Lorraine (UL), Interactions Gènes-Risques environnementaux et Effets sur la Santé (INGRES), Service de Parasitologie-Mycologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Septeos, Cibles et médicaments de l'infection, de l'immunité et du cancer (IICiMed), Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN), and Centre hospitalier universitaire de Nantes (CHU Nantes)

Subjects
[SDV]Life Sciences [q-bio], female genital diseases and pregnancy complications
Abstract

International audience; Introduction. The increase of invasive fungal infections (IFIs) and associated treatment failure in populations at risk is driving us to look for new treatments. Hypothesis. The CIN-102 compound, derived from cinnamon essential oil, could be a new antifungal class with an activity, in particular, on strains resistant to current antifungals but also on biofilms, a factor of virulence and resistance of fungi. Aim. The aim of this study is to show the activity of CIN-102 on various strains resistant to current antifungals, on the biofilm and to determine the possibility of resistance induced with this compound. Methodology. We studied the MIC of CIN-102 and of current antifungals (voriconazole and amphotericin B) using CLSI techniques against eight different strains of three genera of filamentous fungi involved in IFIs and having resistance phenotypes to current antifungals. We also determined their effects on biofilm formation, and the induced resistance by voriconazole (VRC) and CIN-102. Results. MIC values determined for CIN-102 were between 62.5 and 250 µg ml −1 . We demonstrated the antifungal effect of CIN-102 on biofilm, and more particularly on its formation, with 100 % inhibition achieved for most of the strains. CIN-102 at a sub-inhibitory concentration in the medium did not induce resistance in our strains, even after 30 generations. Conclusions. In this study we show that CIN-102 is effective against resistant filamentous fungi and against biofilm formation. In addition, our strains did not acquire a resistance phenotype against CIN-102 over time, unlike with VRC. CIN-102 is therefore an interesting candidate for the treatment of IFIs, including in cases of therapeutic failure linked to resistance, although further studies on its efficacy, safety and mechanism of action are needed.

Published
2021
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33. Collateral consequences of agricultural fungicides on pathogenic yeasts: A One Health perspective to tackle azole resistance

Author

Castelo‐Branco, Débora, primary, Lockhart, Shawn R., additional, Chen, Yee‐Chun, additional, Santos, Daniel Assis, additional, Hagen, Ferry, additional, Hawkins, Nichola Jane, additional, Lavergne, Rose‐Anne, additional, Meis, Jacques F., additional, Le Pape, Patrice, additional, Rocha, Marcos Fabio Gadelha, additional, Sidrim, José Julio Costa, additional, Arendrup, Maiken, additional, and Morio, Florent, additional

Published
2021
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35. Collateral consequences of agricultural fungicides on pathogenic yeasts: a One Health perspective to tackle azole resistance

Author

Castelo-Branco, Débora, Lockhart, Shawn R, Chen, Yee-Chun, Santos, Daniel Assis, Hagen, Ferry, Jane Hawkins, Nichola, Lavergne, Rose-Anne, Meis, Jacques, Le Pape, Patrice, Fabio Gadelha Rocha, Marcos, Julio Costa Sidrim, José, Arendrup, Maiken, Morio, Florent, Castelo-Branco, Débora, Lockhart, Shawn R, Chen, Yee-Chun, Santos, Daniel Assis, Hagen, Ferry, Jane Hawkins, Nichola, Lavergne, Rose-Anne, Meis, Jacques, Le Pape, Patrice, Fabio Gadelha Rocha, Marcos, Julio Costa Sidrim, José, Arendrup, Maiken, and Morio, Florent

Abstract

Candida and Cryptococcus affect millions of people yearly, being responsible for a wide array of clinical presentations, including life-threatening diseases. Interestingly, most human-pathogenic yeasts are not restricted to the clinical setting, as they are also ubiquitous in the environment. Recent studies raise concern regarding the potential impact of agricultural use of azoles on resistance to medical antifungals in yeasts, as previously outlined with Aspergillus fumigatus. Thus, we undertook a narrative review of the literature and provide lines of evidence suggesting that an alternative, environmental route of azole resistance, may develop in pathogenic yeasts, in addition to patient route. However, it warrants sound evidence to support that pathogenic yeasts cross border between plants, animals and humans and that environmental reservoirs may contribute to azole resistance in Candida or other yeasts for humans. As these possibilities could concern public health, we propose a road map for future studies under the One Health perspective.

Published
2021

36. Ultrasound features of fetal toxoplasmosis: A contemporary multicenter survey in 88 fetuses

Author

Codaccioni, Camille, primary, Picone, Olivier, additional, Lambert, Véronique, additional, Maurice, Paul, additional, Pomar, Léo, additional, Winer, Norbert, additional, Guibaud, Laurent, additional, Lavergne, Rose‐Anne, additional, Saliou, Anne‐Hélène, additional, Quinio, Dorothée, additional, Benachi, Alexandra, additional, Noel, Catherine, additional, Ville, Yves, additional, Cuillier, Fabrice, additional, Pomares, Christelle, additional, Ferret, Nicole, additional, Filisetti, Denis, additional, Weingertner, Anne‐Sophie, additional, Vequeau‐Goua, Valérie, additional, Cateau, Estelle, additional, Benoist, Guillaume, additional, Wallon, Martine, additional, Dommergues, Marc, additional, Villena, Isabelle, additional, and Mandelbrot, Laurent, additional

Published
2020
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39. Serum (1 → 3)-β-D-glucan could be useful to rule out invasive candidiasis in neonates with an adapted cut-off.

Author

Cliquennois, Pauline, Scherdel, Pauline, Lavergne, Rose‐Anne, Flamant, Cyril, Morio, Florent, Cohen, Jeremie F., Launay, Elise, Gras Le Guen, Christele, and Lavergne, Rose-Anne

Subjects
INVASIVE candidiasis, RECEIVER operating characteristic curves, NEWBORN infants, AGE, CROSS-sectional method, BETA-glucans, LONGITUDINAL method
Abstract

Aim: We assessed the diagnostic accuracy of serum (1 → 3)-β-D-glucan (BDG) for neonatal invasive candidiasis (NIC) using the recommended cut-off usually used in adults for detecting invasive candidiasis and searched for an optimal cut-off for ruling out NIC.Methods: We conducted a prospective cross-sectional study at Nantes University medical centre from January 2017 to July 2018. All consecutive newborn infants of less than 28 days of corrected age, with clinically suspected NIC, who underwent BDG assay, were included. Sensitivity and specificity were calculated by using the recommended cut-off of 80 pg/mL. Receiver operating characteristic curve analysis was used to identify an optimal cut-off value.Results: We included 55 newborn infants with 61 episodes of suspected NIC. Their median gestational and chronological ages were 28.0 weeks (interquartile range [IQR] 26.4-34.1) and 10.0 days (IQR 6.0-22.0), respectively. Of 61 episodes, seven revealed NIC. Sensitivity and specificity were 85.7% (95% confidence interval [CI] 42.1%-99.6%) and 51.9% (37.8%-65.7%) with the recommended cut-off, respectively. An optimal cut-off of 174 pg/mL offered the same sensitivity but higher specificity 77.8% (64.4%-88.0%).Conclusion: The recommended cut-off of 80 pg/mL was probably too low for ruling out NIC. A higher cut-off might have been more appropriate. [ABSTRACT FROM AUTHOR]

Published
2021
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40. Epidemiology and Clinical Impact of Respiratory Coinfections at Diagnosis of Pneumocystis jirovecii Pneumonia.

Author

Lécuyer, Romain, Issa, Nahema, Tessoulin, Benoit, Lavergne, Rose-Anne, Morio, Florent, Gabriel, Frederic, Canet, Emmanuel, Bressollette-Bodin, Céline, Guillouzouic, Aurélie, Boutoille, David, Raffi, François, Lecomte, Raphael, Turnier, Paul Le, Deschanvres, Colin, Camou, Fabrice, Gaborit, Benjamin Jean, Group, PRONOCYSTIS Study, Le Turnier, Paul, and PRONOCYSTIS Study Group

Subjects
PNEUMOCYSTIS pneumonia, MIXED infections, CLINICAL epidemiology, DIAGNOSIS, ODDS ratio, HIV infection epidemiology, HIV infection complications, CYTOMEGALOVIRUS disease diagnosis, CYTOMEGALOVIRUSES, CYTOMEGALOVIRUS diseases, FUNGI, RETROSPECTIVE studies, DISEASE complications
Abstract

Background: The role of respiratory coinfections at diagnosis of Pneumocystis jirovecii pneumonia (PcP) on clinical impact has been underestimated.Methods: A retrospective observational study was conducted January 2011 to April 2019 to evaluate respiratory coinfections at diagnosis of PcP patients in 2 tertiary care hospitals. Coinfection was defined by identification of pathogens from P. jirovecii-positive samples.Results: Of 7882 respiratory samples tested for P. jirovecii during the 8-year study, 328 patients with diagnosis of PcP were included. Mean age was 56.7 (SD 14.9) years, 193 (58.8%) were male, 74 (22.6%) had positive HIV serology, 125 (38.1%) had viral coinfection, 76 (23.2%) bacterial coinfection, and 90-day mortality was 25.3%. In the overall population, 90-day mortality was independently associated with solid tumor underlying disease (odds ratio [OR], 11.8; 95% confidence interval [CI], 1.90-78.0; P = .008), sepsis-related organ failure assessment score (SOFA) at admission (OR, 1.62; 95% CI, 1.34-2.05; P< .001), and cytomegalovirus (CMV) respiratory coinfection (OR, 3.44; 95% CI, 1.24-2.90; P = .02). Among HIV-negative patients, respiratory CMV coinfection was associated with worse prognosis, especially when treated with adjunctive corticosteroid therapy.Conclusions: Respiratory CMV coinfection at PcP diagnosis was independently associated with increased 90-day mortality, specifically in HIV-negative patients. [ABSTRACT FROM AUTHOR]

Published
2022
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41. Collateral consequences of agricultural fungicides on pathogenic yeasts: A One Health perspective to tackle azole resistance.

Author

Castelo‐Branco, Débora, Lockhart, Shawn R., Chen, Yee‐Chun, Santos, Daniel Assis, Hagen, Ferry, Hawkins, Nichola Jane, Lavergne, Rose‐Anne, Meis, Jacques F., Le Pape, Patrice, Rocha, Marcos Fabio Gadelha, Sidrim, José Julio Costa, Arendrup, Maiken, and Morio, Florent

Subjects
AZOLES, FUNGICIDES, YEAST, ASPERGILLUS fumigatus, ROAD maps, ANTIFUNGAL agents
Abstract

Candida and Cryptococcus affect millions of people yearly, being responsible for a wide array of clinical presentations, including life‐threatening diseases. Interestingly, most human pathogenic yeasts are not restricted to the clinical setting, as they are also ubiquitous in the environment. Recent studies raise concern regarding the potential impact of agricultural use of azoles on resistance to medical antifungals in yeasts, as previously outlined with Aspergillus fumigatus. Thus, we undertook a narrative review of the literature and provide lines of evidence suggesting that an alternative, environmental route of azole resistance, may develop in pathogenic yeasts, in addition to patient route. However, it warrants sound evidence to support that pathogenic yeasts cross border between plants, animals and humans and that environmental reservoirs may contribute to azole resistance in Candida or other yeasts for humans. As these possibilities could concern public health, we propose a road map for future studies under the One Health perspective. [ABSTRACT FROM AUTHOR]

Published
2022
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42. The Novodiag® Stool parasites assay, an innovative high-plex technique for fast detection of protozoa, helminths and microsporidia in stool samples: a retrospective and prospective study.

Author

Hartuis, Sophie, Lavergne, Rose-Anne, Nourrisson, Céline, Verweij, Jaco, Desoubeaux, Guillaume, Lussac-Sorton, Florian, Lemoine, Jean-Philippe, Cateau, Estelle, Jeddi, Fakhri, Poirier, Philippe, Le Pape, Patrice, and Morio, Florent

Abstract

Copyright of Parasite (1252607X) is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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43. Assessment of the first commercial multiplex PCR kit (ParaGENIE Crypto-Micro Real-Time PCR) for the detection of Cryptosporidium spp., Enterocytozoon bieneusi, and Encephalitozoon intestinalis from fecal samples

Author

Morio, Florent, primary, Poirier, Philippe, additional, Le Govic, Yohann, additional, Laude, Adrien, additional, Valot, Stéphane, additional, Desoubeaux, Guillaume, additional, Argy, Nicolas, additional, Nourrisson, Céline, additional, Pomares, Christelle, additional, Machouart, Marie, additional, Dalle, Frédéric, additional, Botterel, Françoise, additional, Bourgeois, Nathalie, additional, Cateau, Estelle, additional, Leterrier, Marion, additional, Beser, Jessica, additional, Lavergne, Rose-Anne, additional, and Le Pape, Patrice, additional

Published
2019
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45. Rapid diagnostic tests relying on antigen detection from stool as an efficient point of care testing strategy for giardiasis and cryptosporidiosis? Evaluation of a new immunochromatographic duplex assay

Author

Goudal, Adeline, primary, Laude, Adrien, additional, Valot, Stéphane, additional, Desoubeaux, Guillaume, additional, Argy, Nicolas, additional, Nourrisson, Céline, additional, Pomares, Christelle, additional, Machouart, Marie, additional, Le Govic, Yohann, additional, Dalle, Frédéric, additional, Botterel, Françoise, additional, Bourgeois, Nathalie, additional, Cateau, Estelle, additional, Leterrier, Marion, additional, Lavergne, Rose-Anne, additional, Beser, Jessica, additional, Le Pape, Patrice, additional, and Morio, Florent, additional

Published
2019
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46. Prenatal therapy with pyrimethamine + sulfadiazine vs spiramycin to reduce placental transmission of toxoplasmosis: a multicenter, randomized trial

Author

Mandelbrot, Laurent, primary, Kieffer, François, additional, Sitta, Rémi, additional, Laurichesse-Delmas, Hélène, additional, Winer, Norbert, additional, Mesnard, Louis, additional, Berrebi, Alain, additional, Le Bouar, Gwenaëlle, additional, Bory, Jean-Paul, additional, Cordier, Anne-Gaëlle, additional, Ville, Yves, additional, Perrotin, Franck, additional, Jouannic, Jean-Marie, additional, Biquard, Florence, additional, d’Ercole, Claude, additional, Houfflin-Debarge, Véronique, additional, Villena, Isabelle, additional, Thiébaut, Rodolphe, additional, Pons, Denis, additional, Nourrisson, C., additional, Lavergne, Rose-Anne, additional, Fillaux, Judith, additional, Assouline, Corinne, additional, Robert-Gangneux, Florence, additional, L’Ollivier, Coralie, additional, Bretelle, Florence, additional, Guidicelli, Béatrice, additional, Garcia, Patricia, additional, Cordier, Anne-Gaelle, additional, Benachi, Alexandra, additional, Vauloup-Fellous, Christelle, additional, Letamendia, Emmanuelle, additional, Bougnoux, Marie-Elisabeth, additional, Van Langendonck, Nathalie, additional, Potin, Jérôme, additional, Marty, Pierre, additional, Pomarès, Christelle, additional, Trastour, Cynthia, additional, Deleplancque, Anne Sophie, additional, Costa, Jean-Marc, additional, Chève, Marie-Thérèse, additional, Col, Jean-Yves, additional, Cimon, Bernard, additional, Sterkers, Y., additional, Lachaud, Laurence, additional, Burlet, Gilles, additional, Maréchaud, Martine, additional, Perraud, Estelle, additional, Grébille, Anne-Gaelle, additional, Valentin, Morgane, additional, Houzé, Sandrine, additional, Omnès, Sophie, additional, Chitrit, Yvon, additional, Boissinot, Christine, additional, Yéra, Hélène, additional, Anselem, Olivia, additional, Tsatsaris, Vassilis, additional, Sénat, Marie-Victoire, additional, Fuchs, Florent, additional, Angoulvant, Adela, additional, Muszynski, Charles, additional, Totet, Anne, additional, Noël, Catherine, additional, Bidat, Laurent, additional, Barjat, Tiphaine, additional, Flori, Pierre, additional, Pelloux, Hervé, additional, Brenier-Pinchart, Marie-Pierre, additional, Thong-Vanh, Catherine, additional, Mandelbrot, Laurent, additional, Floch, Corinne, additional, Carbillon, Lionel, additional, Lachassine, Eric, additional, Ricbourg, Aude, additional, Paris, Luc, additional, Dommergues, Marc, additional, Rousseau, Thierry, additional, Dalle, Frederic, additional, Dardé, Marie Laure, additional, Aubard, Véronique, additional, Olivier, Camille, additional, Verspyk, Eric, additional, and Favennec, Loic, additional

Published
2018
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48. Characteristics and Prognosis Factors of Pneumocystis jiroveciiPneumonia According to Underlying Disease

Author

Lécuyer, Romain, Issa, Nahéma, Camou, Fabrice, Lavergne, Rose-anne, Gabriel, Frederic, Morio, Florent, Canet, Emmanuel, Raffi, François, Boutoille, David, Cady, Anne, Gousseff, Marie, Crabol, Yoann, Néel, Antoine, Tessoulin, Benoît, Gaborit, Benjamin, Raffi, Francois, Boutoille, David, Biron, Charlotte, Lefebvre, Maeva, Gaborit, Benjamin Jean, Le Turnier, Paul, Deschanvres, Colin, Lecomte, Raphael, Chauveau, Marie, Lécuyer, Romain, Asquier-Khati, Antoine, Le Pape, Patrice, Morio, Florent, Lavergne, Rose-Anne, Jeddi, Fakhri, Corvec, Stéphane, Bemer, Pascale, Caillon, Jocelyne, Guillouzouic, Aurélie, Leroy, Anne-Gaëlle, Lakhal, Karim, Cinotti, Raphaël, Roquilly, Antoine, Emmanuel Canet, Jean Reignier, Blanc, François Xavier, Bretonniere, Cédric, Morin, Paul, Camou, Fabrice, Issa, Nahéma, Guisset, Olivier, Mourissoux, Gaelle, Accoceberry, Isabelle, Gabriel, Frederic, Accoceberry, Isabelle, Coron, Noémie, Delhaes, Laurence, Imbert, Sébastien, Lefranc, Maxime, Lussac-Sorton, Florian, Rougeron, Amandine, Gousseff, Marie, Crabol, Yoann, Corvaisier, Grégory, Lautredoux, Florent, Lécuyer, Romain, Cady, Anne, Auger, Myriam, and Pouedras, Pascal

Abstract

Pneumocystis jiroveciipneumonia (PcP) remains associated with high rates of mortality, and the impact of immunocompromising underlying disease on the clinical presentation, severity, and mortality of PcP has not been adequately evaluated.

Published
2024
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49. Multiple fungicide-driven alterations in azole-resistant Aspergillus fumigatus, Colombia, 2015

Author

Le Pape, Patrice, Lavergne, Rose-Anne, Morio, Florent, and Alvarez-Moreno, Carlos

Subjects
Usage, Physiological aspects, Research, Demographic aspects, Fungicides -- Usage -- Research, Aspergillus -- Physiological aspects -- Research, Microbial drug resistance -- Demographic aspects -- Research
Abstract

To the Editor: We read with interest the report by van der Linden et al. about the prevalence of azole-resistant Aspergillus fumigatus isolates from 19 countries, including 2 from the [...]

Published
2016

50. PCR‐based detection of Aspergillus fumigatus and absence of azole resistance due to TR34/L98H in a french multicenter cohort of 137 patients with fungal rhinosinusitis

Author

Morio, Florent, primary, Dannaoui, Eric, additional, Chouaki, Taieb, additional, Cateau, Estelle, additional, Malard, Olivier, additional, Bonfils, Pierre, additional, Page, Cyril, additional, Dufour, Xavier, additional, Cottrel, Claire, additional, Erwan, Tamic, additional, Lavergne, Rose‐Anne, additional, and Le Pape, Patrice, additional

Published
2017
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