402 results on '"Lawrence, Roger"'
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2. Environment
3. Galactokinase 1 is the source of elevated galactose‐1‐phosphate and cerebrosides are modestly reduced in a mouse model of classic galactosemia.
4. Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type.
5. Arylsulfatase K is the Lysosomal 2‑Sulfoglucuronate Sulfatase
6. Expanding the 3‑O‑Sulfate ProteomeEnhanced Binding of Neuropilin‑1 to 3‑O‑Sulfated Heparan Sulfate Modulates Its Activity
7. Expanding the 3-O-Sulfate Proteome--Enhanced Binding of Neuropilin-1 to 3-O-Sulfated Heparan Sulfate Modulates Its Activity.
8. Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo
9. Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B
10. Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling.
11. Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB
12. Motors, Drives, and Electric Energy Management
13. Intra-articular enzyme replacement therapy with rhIDUA is safe, well-tolerated, and reduces articular GAG storage in the canine model of mucopolysaccharidosis type I.
14. Intra-articular enzyme replacement therapy with rhIDUA is safe, well-tolerated, and reduces articular GAG storage in the canine model of mucopolysaccharidosis type I.
15. Heparan sulfate expression in the neural crest is essential for mouse cardiogenesis.
16. 3‐O‐sulfation provides high affinity binding to neuropilin‐1 and modulates endothelial cell sprouting and neuronal growth cone collapse (607.7)
17. Glycan-based biomarkers for mucopolysaccharidoses
18. The Gilberts take the plunge
19. Kiribati: Change and Context in an Atoll World
20. Hepatic Remnant Lipoprotein Clearance by Heparan Sulfate Proteoglycans and Low-Density Lipoprotein Receptors Depend on Dietary Conditions in Mice
21. Central nervous system pathology in preclinical MPS IIIB dogs reveals progressive changes in clinically relevant brain regions
22. A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis
23. N -glycolyl groups of nonhuman chondroitin sulfates survive in ancient fossils
24. Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction
25. Tralesinidase Alfa Enzyme Replacement Therapy Prevents Disease Manifestations in a Canine Model of Mucopolysaccharidosis Type IIIB
26. Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice
27. Borders at the edge of the enlarged European Union: barriers or bridges?
28. Surfen, a Small Molecule Antagonist of Heparan Sulfate
29. The Benefit of Joining WTO
30. Differentiation of 3-O-Sulfated Heparin Disaccharide Isomers: Identification of Structural Aspects of the Heparin CCL2 Binding Motif
31. Representation at National Insurance Tribunals: A Research Note
32. Biochemical evaluation of intracerebroventricular rhNAGLU-IGF2 enzyme replacement therapy in neonatal mice with Sanfilippo B syndrome
33. Heat and Harmonics: Solutions to Concerns in Air-Cooled Medium-Voltage Adjustable-Speed Drives
34. Step-by-Step Training Video and Manual for the Physical Examination
35. Natural history study of glycan accumulation in large animal models of GM2 gangliosidoses
36. Intracerebroventricular enzyme replacement therapy with β-galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice
37. Characterization of disease-specific chondroitin sulfate nonreducing end accumulation in mucopolysaccharidosis IVA
38. Characterization of glycan substrates accumulating in GM1 Gangliosidosis
39. CHO Glycosylation Mutants: Proteoglycans
40. Mapping critical biological motifs and biosynthetic pathways of heparan sulfate
41. Disseminated Flavimonas oryzihabitans Infection in a Diabetic Patient Who Presented with Suspected Multiple Splenic Abscesses
42. Heat & Harmonics - the Most Significant Concerns in Air-Cooled Medium Voltage Adjustable Speed Drives & What to Do about It?
43. Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B
44. BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis
45. BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis
46. A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis
47. Pharmacology of BMN 250 administered via intracerebroventricular infusion once every 2 weeks for twenty-six weeks or longer in a canine model of mucopolysaccharidosis type IIIB
48. Translational dose-response and frequency scaling for BMN 250 administered via the intracerebroventricular route: Predicting a clinically effective dosing regimen from animal models of disease for the treatment of Sanfilippo syndrome type B
49. Standard Updates for Adjustable-Speed ac Drives: The Performance Standard for Drives Rated 375 kW and Larger
50. The Influence of Charting Upon Liability Determinations
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