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13 results on '"Lazzarin, Roberta"'

1. How histopathological diagnosis interacts with kidney ultrasound parameters and glomerular filtration rate

Author

Andrulli, Simeone, Gigante, Antonietta, Rossini, Michele, D’Angio’, Pierluigi, Vischini, Gisella, Luchetta, Franca, Aucella, Filippo, Valsecchi, Giovanni, Infante, Barbara, Vario, Maria Giovanna, Giannese, Domenico, Granata, Antonio, Moggia, Elisabetta, Gembillo, Guido, Cianci, Rosario, Bonomini, Mario, Manenti, Flavia, Lazzarin, Roberta, Renzo, Brigida Di, Zanchelli, Fulvia, Garozzo, Maurizio, Manes, Massimo, Battaglia, Yuri, Sciri, Raffaela, Fabritiis, Marco De, Quaglia, Marco, Cavoli, Gioacchino Li, Gintoli, Enrica, Conte, Maria Maddalena, Borzumati, Maurizio, Benozzi, Luisa, Pasquariello, Giovanna, Andrulli, Giovanni, Leoni, Marco, Seminara, Giuseppe, Corbani, Valentina, Sabiu, Gianmarco, Maggio, Arcangelo Di, Pollastro, Rosa Maria, and Gesualdo, Loreto

Published
2024
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2. The safety of corticosteroid therapy in IGA nephropathy: analysis of a real-life Italian cohort

Author

Baragetti, Ivano, Del Vecchio, Lucia, Ferrario, Francesca, Alberici, Federico, Amendola, Andrea, Russo, Elisa, Ponti, Serena, Di Palma, Anna Maria, Pani, Antonello, Rollino, Cristiana, Giannese, Domenico, Boscutti, Giuliano, Sorrentino, Annasara, Colturi, Carla, Brunori, Giuliano, Lazzarin, Roberta, Catapano, Fausta, Cozzolino, Mario, Feriozzi, Sandro, and Pozzi, Claudio

Published
2024
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3. The Role of Rituximab in Primary Focal Segmental Glomerular Sclerosis of the Adult

Author

Affatato, Stefania, Caroti, Leonardo, Mancini, Elena, Semeraro, Luca, Siligato, Rossella, Arnaldo Cassia, Matthias, Napodano, Pietro, Calatroni, Marta, Distratis, Cosimo, Campo, Andrea, Tedesco, Martina, Mescia, Federica, Pisani, Isabella, Allinovi, Marco, Casazza, Giovanni, Del Vecchio, Lucia, Santostefano, Marisa, Cirillo, Luigi, Ferrario, Francesca, Esposito, Ciro, Esposito, Pasquale, Santoro, Domenico, Lazzarin, Roberta, Rossi, Giovanni Maria, Fiaccadori, Enrico, Ferrantelli, Angelo, Sinico, Renato Alberto, Cozzolino, Mario, Gallieni, Maurizio, Cirami, Lino, Scolari, Francesco, Vaglio, Augusto, and Alberici, Federico

Published
2022
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4. How histopathological diagnosis interacts with kidney ultrasound parameters to predict glomerular filtration rate

Author

Andrulli, Simeone, primary, Gigante, A, additional, Rossini, Michele, additional, D'Angiò, Pierluigi, additional, Vischini, Gisella, additional, Lucchetta, Franca, additional, Aucella, Filippo, additional, Valsecchi, Giovanni, additional, Infante, Barbara, additional, Vario, Maria Giovanna, additional, Giannese, Domenico, additional, Granata, Antonio, additional, Moggia, Elisabetta, additional, Gembillo, Guido, additional, Cianci, Rosario, additional, Bonomini, Mario, additional, Manenti, Flavia, additional, Lazzarin, Roberta, additional, Renzo, Brigida Di, additional, Zanchelli, Fulvia, additional, Garozzo, Maurizio, additional, Manes, Massimo, additional, Battaglia, Yuri, additional, Sciri, Raffaella, additional, De Fabritiis, Marco, additional, Quaglia, Marco, additional, Cavoli, Gioacchino Li, additional, Gintoli, Enrica, additional, Conte, Maria Maddalena, additional, Borzumati, Maurizio, additional, Benozzi, Luisa, additional, Pasquariello, Giovanna, additional, Andrulli, Giovanni, additional, Leoni, Marco, additional, Seminara, Giuseppe, additional, Corbari, Valentina, additional, Sabiu, Gianmarco, additional, Maggio, Arcangelo Di, additional, Pollastro, Rosa Maria, additional, and Gesualdo, Loreto, additional

Published
2024
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5. The Role of Rituximab in Primary Focal Segmental Glomerular Sclerosis of the Adult

Author

Tedesco, Martina, primary, Mescia, Federica, additional, Pisani, Isabella, additional, Allinovi, Marco, additional, Casazza, Giovanni, additional, Del Vecchio, Lucia, additional, Santostefano, Marisa, additional, Cirillo, Luigi, additional, Ferrario, Francesca, additional, Esposito, Ciro, additional, Esposito, Pasquale, additional, Santoro, Domenico, additional, Lazzarin, Roberta, additional, Rossi, Giovanni Maria, additional, Fiaccadori, Enrico, additional, Ferrantelli, Angelo, additional, Sinico, Renato Alberto, additional, Cozzolino, Mario, additional, Gallieni, Maurizio, additional, Cirami, Lino, additional, Scolari, Francesco, additional, Vaglio, Augusto, additional, Alberici, Federico, additional, Affatato, Stefania, additional, Caroti, Leonardo, additional, Mancini, Elena, additional, Semeraro, Luca, additional, Siligato, Rossella, additional, Arnaldo Cassia, Matthias, additional, Napodano, Pietro, additional, Calatroni, Marta, additional, Distratis, Cosimo, additional, and Campo, Andrea, additional

Published
2022
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6. The Role of Rituximab in Primary Focal Segmental Glomerulosclerosis of the Adult

Author

Tedesco, M, Mescia, F, Pisani, I, Allinovi, M, Casazza, G, Del Vecchio, L, Santostefano, M, Cirillo, L, Ferrario, F, Esposito, C, Esposito, P, Santoro, D, Lazzarin, R, Rossi, G, Fiaccadori, E, Ferrantelli, A, Sinico, R, Cozzolino, M, Gallieni, M, Cirami, L, Scolari, F, Vaglio, A, Alberici, F, Affatato, S, Caroti, L, Mancini, E, Semeraro, L, Siligato, R, Cassia, M, Napodano, P, Calatroni, M, Distratis, C, Campo, A, Tedesco, Martina, Mescia, Federica, Pisani, Isabella, Allinovi, Marco, Casazza, Giovanni, Del Vecchio, Lucia, Santostefano, Marisa, Cirillo, Luigi, Ferrario, Francesca, Esposito, Ciro, Esposito, Pasquale, Santoro, Domenico, Lazzarin, Roberta, Rossi, Giovanni Maria, Fiaccadori, Enrico, Ferrantelli, Angelo, Sinico, Renato Alberto, Cozzolino, Mario, Gallieni, Maurizio, Cirami, Lino, Scolari, Francesco, Vaglio, Augusto, Alberici, Federico, Affatato, Stefania, Caroti, Leonardo, Mancini, Elena, Semeraro, Luca, Siligato, Rossella, Cassia, Matthias Arnaldo, Napodano, Pietro, Calatroni, Marta, Distratis, Cosimo, Campo, Andrea, Tedesco, M, Mescia, F, Pisani, I, Allinovi, M, Casazza, G, Del Vecchio, L, Santostefano, M, Cirillo, L, Ferrario, F, Esposito, C, Esposito, P, Santoro, D, Lazzarin, R, Rossi, G, Fiaccadori, E, Ferrantelli, A, Sinico, R, Cozzolino, M, Gallieni, M, Cirami, L, Scolari, F, Vaglio, A, Alberici, F, Affatato, S, Caroti, L, Mancini, E, Semeraro, L, Siligato, R, Cassia, M, Napodano, P, Calatroni, M, Distratis, C, Campo, A, Tedesco, Martina, Mescia, Federica, Pisani, Isabella, Allinovi, Marco, Casazza, Giovanni, Del Vecchio, Lucia, Santostefano, Marisa, Cirillo, Luigi, Ferrario, Francesca, Esposito, Ciro, Esposito, Pasquale, Santoro, Domenico, Lazzarin, Roberta, Rossi, Giovanni Maria, Fiaccadori, Enrico, Ferrantelli, Angelo, Sinico, Renato Alberto, Cozzolino, Mario, Gallieni, Maurizio, Cirami, Lino, Scolari, Francesco, Vaglio, Augusto, Alberici, Federico, Affatato, Stefania, Caroti, Leonardo, Mancini, Elena, Semeraro, Luca, Siligato, Rossella, Cassia, Matthias Arnaldo, Napodano, Pietro, Calatroni, Marta, Distratis, Cosimo, and Campo, Andrea

Abstract

Introduction: Primary focal segmental glomerular sclerosis (FSGS) is a rare, likely immune-mediated disease. Rituximab (RTX) may play a role in management, although data in adults are scanty. Methods: We collected cases of RTX-treated primary FSGS within the Italian Society of Nephrology Immunopathology Working Group and explored response rate (24-hour proteinuria <3.5 g and <50% compared with baseline, stable estimated glomerular filtration rate). Results: A total of 31 patients were followed for at least 12 months; further follow-up (median 17 months, interquartile range [IQR] 15–33.5) was available for 11. At first RTX administration, median creatinine and 24-hour proteinuria were 1.17 mg/dl (IQR 0.83–1.62) and 5.2 g (IQR 3.3–8.81), respectively. Response rate at 3, 6, and 12 months was 39%, 52%, and 42%, respectively. In the first 12 months, creatinine level remained stable whereas proteinuria and serum albumin level improved, with an increase in the proportion of patients tapering other immunosuppressants. There were 6 patients who were retreated with RTX within 12 months, either for proteinuria increase or refractory disease; only the 2 responders to the first RTX course experienced a further response. At univariate analysis, 6-month response was more frequent in steroid-dependent patients (odds ratio [OR] 7.7 [95% CI 1.16–52.17]) and those with proteinuria <5 g/24 h (OR 8.25 [1.45–46.86]). During long-term follow-up, 4 of 5 responders at 12 months maintained a sustained response, either without further immunosuppression (2 of 4) or with pre-emptive RTX (2 of 4); 1 relapsed and responded to RTX retreatment. Conclusion: RTX may be an option in primary FSGS, especially in steroid-dependent patients, with 24-hour proteinuria <5 g and previously responders to RTX. Optimal long-term management for responders is unclear, with some patients experiencing sustained remission and others requiring RTX retreatment, either preemptive or after rising proteinuria

Published
2022

8. P0372RITUXIMAB IN IDIOPATHIC FOCAL SEGMENTAL GLOMERULOSCLEROSIS OF THE ADULT: A MULTICENTRE RETROSPECTIVE SURVEY OF 31 PATIENTS

Author

Alberici, F, Vaglio, A, Cirami, C, Scolari, F, Gallieni, M, Cozzolino, M, Sinico, R, Ferrantelli, A, Delbarba, E, Lazzarin, R, Santoro, D, Esposito, P, Esposito, C, Ferrario, F, Santostefano, M, Del Vecchio, L, Casazza, G, Allinovi, M, Pisani, I, Tedesco, M, Alberici, Federico, Vaglio, Augusto, Cirami, Calogero, Scolari, Francesco, Gallieni, Maurizio, Cozzolino, Mario Gennaro, Sinico, Renato A, Ferrantelli, Angelo, Delbarba, Elisa, Lazzarin, Roberta, Santoro, Domenico, Esposito, Pasquale, Esposito, Ciro, Ferrario, Francesca, Santostefano, Marisa, Del Vecchio, Lucia, Casazza, Giovanni, Allinovi, Marco, Pisani, Isabella, Tedesco, Martina, Alberici, F, Vaglio, A, Cirami, C, Scolari, F, Gallieni, M, Cozzolino, M, Sinico, R, Ferrantelli, A, Delbarba, E, Lazzarin, R, Santoro, D, Esposito, P, Esposito, C, Ferrario, F, Santostefano, M, Del Vecchio, L, Casazza, G, Allinovi, M, Pisani, I, Tedesco, M, Alberici, Federico, Vaglio, Augusto, Cirami, Calogero, Scolari, Francesco, Gallieni, Maurizio, Cozzolino, Mario Gennaro, Sinico, Renato A, Ferrantelli, Angelo, Delbarba, Elisa, Lazzarin, Roberta, Santoro, Domenico, Esposito, Pasquale, Esposito, Ciro, Ferrario, Francesca, Santostefano, Marisa, Del Vecchio, Lucia, Casazza, Giovanni, Allinovi, Marco, Pisani, Isabella, and Tedesco, Martina

Abstract

Idiopathic Focal Segmental Glomerulosclerosis (FSGS) is a rare glomerulonephritis often complicated by a chronic relapsing course frequently characterized by dependency or resistance to immunosuppressive treatment. Moreover, about half of the patients with active disease would develop end-stage renal disease within 10 years from the diagnosis, highlighting the need of novel therapeutic approaches. Rituximab (RTX), a chimeric monoclonal antibody against CD20, showed promising results in pediatric steroid-dependent/frequently relapsing FSGS and in post-transplantation recurrence. However, evidence about its role in the FSGS of the adult is still lacking with small case series suggesting conflicting results. In this study we assess the efficacy of RTX in the largest cohort of adults with FSGS currently available in literature.

Published
2020

9. P0372RITUXIMAB IN IDIOPATHIC FOCAL SEGMENTAL GLOMERULOSCLEROSIS OF THE ADULT: A MULTICENTRE RETROSPECTIVE SURVEY OF 31 PATIENTS

Author

Tedesco, Martina, primary, Pisani, Isabella, primary, Allinovi, Marco, primary, Casazza, Giovanni, primary, Del Vecchio, Lucia, primary, Santostefano, Marisa, primary, Ferrario, Francesca, primary, Esposito, Ciro, primary, Esposito, Pasquale, primary, Santoro, Domenico, primary, Lazzarin, Roberta, primary, Delbarba, Elisa, primary, Ferrantelli, Angelo, primary, Sinico, Renato A, primary, Cozzolino, Mario Gennaro, primary, Gallieni, Maurizio, primary, Scolari, Francesco, primary, Cirami, Calogero, primary, Vaglio, Augusto, primary, and Alberici, Federico, primary

Published
2020
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10. MP180PORPHYRIA CUTANEA TARDA (PCT), HEMODIALYSIS AND HEPATITIS C: AN OPEN CHALLENGE FOR DIAGNOSIS AND TREATMENT

Author

Favaro, Enrico, primary, Lazzarin, Roberta, additional, Davoli, Carla, additional, Nicolli, Annamaria, additional, Trevisan, Andrea, additional, Mele, Alessandra Antonia, additional, Guizzo, Marta, additional, Ferraro, Alberto, additional, Pierobon, Erika, additional, Cremasco, Daniela, additional, and Abaterusso, Cataldo, additional

Published
2017
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11. Persistent Secondary Hyperparathyroidism and Vertebral Fractures in Kidney Transplantation: Role of Calcium-Sensing Receptor Polymorphisms and Vitamin D Deficiency

Author

Giannini, Sandro, primary, Sella, Stefania, additional, Silva-Netto, Fatima, additional, Cattelan, Catia, additional, Carbonare, Luca Dalle, additional, Lazzarin, Roberta, additional, Marchini, Francesco, additional, Rigotti, Paolo, additional, Marcocci, Claudio, additional, Cetani, Filomena, additional, Pardi, Elena, additional, D'Angelo, Angela, additional, Realdi, Giuseppe, additional, and Bonfante, Luciana, additional

Published
2009
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12. Persistent Secondary Hyperparathyroidism and Vertebral Fractures in Kidney Transplantation: Role of Calcium-Sensing Receptor Polymorphisms and Vitamin D Deficiency.

Author

Giannini, Sandro, Sella, Stefania, Netto, Fatima Silva, Cattelan, Catia, Carbonare, Luca Dalle, Lazzarin, Roberta, Marchini, Francesco, Rigotti, Paolo, Marcocci, Claudio, Cetani, Filomena, Pardi, Elena, D'Angelo, Angela, Realdi, Giuseppe, and Bonfante, Luciana

Abstract

The article discusses the result of a study which investigated the role of vitamin D deficiency and calcium-sensing receptor polymorphisms in persistent vertebral fractures and secondary hyperparathyroidism (SHPT) in kidney transplantation. It was found that low 25-vitamin D is involved in the pathogenesis of SHPT and it is a common feature after kidney transplantation. The study also suggests that high parathyroid hormone level is associated with an increased risk for vertebral fractures.

Published
2010
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13. Double urine circulation: importance of pores.

Author

Antonello A, D'Angelo A, Nalesso F, Capezzi M, Malagoli A, Pastori G, Lazzarin R, Calò L, Bonfante L, and Gambaro G

Subjects
France, History, 17th Century, History, 18th Century, Humans, Urine, Urology history
Abstract

The authors examine a presentation to the Royal Academy of Sciences of Paris by L. Morin, French physician and meteorologist. In this communication the presence of "pores" in the stomach and the bladder, which would allow a quick elimination of the urines on the occasion of an abundant fluid intake.

Published
2003

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