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Objective: Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare congenital disorder that results in vaginal agenesis. Lee's neovaginoplasty is a novel surgery for reconstructing the vagina. Transneovaginal oocyte retrieval completely changes the scope of fertility for patients with MRKH syndrome who have undergone neovaginal reconstruction. Case report: A 22-year-old female with type 1 MRKH syndrome underwent Lee's neovaginoplasty successfully. Four years later, she sought embryo cryopreservation consultation and underwent controlled ovarian hyperstimulation. Upon examination, her anti-Müllerian hormone level was 1.97 ng/ml and she had only eight antral follicles. The neovaginal length was 8 cm with elasticity and extensibility. Transneovaginal oocyte retrieval was performed under ultrasound guidance, and seven oocytes were retrieved. The follicle-to-oocyte index was 87.5%. Conclusion: Lee's neovaginoplasty is a promising surgery for reconstructing the vagina in MRKH syndrome, and this case shows that transneovaginal oocyte retrieval can be successfully performed after vaginal reconstruction. This technique provides a minimally invasive option for retrieving oocytes in patients of MRKH syndrome.

Soluble phosphorus (P) and P uptake are heavily affected by adverse conditions, such as salinity and acidity. The study aimed to evaluate the effects of P-solubilizing purple nonsulfur bacteria (PSPNSB) Cereibacter sphaeroides on soil characteristics, P uptake, growth, and yield of rice planted in saline soil in Thoi Binh – Ca Mau under greenhouse conditions. The pot experiment was completely randomized in blocks with two factors. Factor A was the rate of phosphorus chemical fertilization at 0, 25, 50, 75, and 100% P according to the recommendation. Factor B was the PSPNSB including a single strain of C. sphaeroides ST16 or C. sphaeroides ST26 and a mixture of them. The soluble P in soil increased by 16.4–18.2% when C. sphaeroides ST16 and ST26 were supplied singly or in the mixture, leading to the increase in total P uptake in rice by 19.2–30.1% in two continuous crops. Moreover, the growth and yield components of rice were also improved, leading to an increase in rice grain yield by 7.20–17.7%. Moreover, supplying the C. sphaeroides strains reduced Na+ in soil and Na content in stem, leaves, and grains, leading to the reduction in proline content in rice. Supplying the C. sphaeroides ST16 and ST26 or their mixture replaced 100% P fertilizer but still ensured the rice grain yield. Further approaches should be made to investigate the possibility of the potent strains replacing chemical P fertilizers under field conditions.

Phosphorus (P) is one of the essential macronutrients for crops. It is present in soil in two forms: soluble and insoluble. However, plants cannot absorb the insoluble forms, including Al-P, Fe-P, and Ca-P; thus, the phosphorus use efficiency is reduced. Therefore, the biological approaches should focus more on sustainable agriculture to overcome this constraint. This article cites publications relating to the biological P solubilizer group of bacteria, which have a highly potential adaptation to many conditions in soils. Among the biological approaches, purple nonsulfur bacteria (PNSB) are a potent group of bacteria according to their adaptability in acidic, saline, and toxic conditions based on their mechanisms in producing exopolymeric substances and siderophores under such adverse environments like acid-sulfate and saline soils. PNSB can solubilize P in soil to have more P availability for soil microbes and plants. This particular group of bacteria has been widely applied in liquid and solid forms from agricultural waste to promote plant growth under submerged conditions. Moreover, this article summarized the P-solubilizing mechanisms of P-solubilizing bacteria and introduced future research perspectives on patterns of PNSB in aspects of nutrient-providing potency, plant growth-promoting capability, and biological control capacity. However, the specific mechanisms of P solubilization by PNSB have not been well documented since the P-solubilizing mechanisms have been investigated on general P-solubilizing bacteria. Thus, specific pathways and metabolites relating to the P-solubilizing PNSB should be investigated, and attention should be addressed to them soon.

BackgroundSocial prescribing (SP) takes a holistic approach to health by linking clients from clinical settings to community programs to address their nonmedical needs. The emerging evidence base for SP demonstrates variability in the design and implementation of different SP initiatives. To effectively address these needs, coproduction among clients, communities, stakeholders, and policy makers is important for tailoring SP initiatives for optimal uptake. ObjectiveThis study aims to explore the role of coproduction in SP initiatives. The research question is as follows: How and for what purpose has coproduction been incorporated across a range of SP initiatives for different clients? MethodsA review of international literature will be conducted following the JBI guidelines for scoping reviews. We will search multiple databases including Scopus, MEDLINE, and the PAIS Index, as well as gray literature, from 2000 to 2023. The primary studies included will describe a nonmedical need for clients, a nonmedical SP program or initiative, coproduction of the SP program, and any follow-up. Review articles and commentaries will be excluded. Titles, abstracts, and full-text articles will be screened, and data will be extracted by at least 2 research team members using Covidence and a pilot-tested extraction template. Clients with lived experience will also participate in the research process. Findings will be descriptively summarized and thematically synthesized to answer the research question. ResultsThe project was funded in 2023, and the results are expected to be submitted for publication in early 2025. ConclusionsDescriptions of what coproduction is meant to accomplish may differ from theoretical aspirations. Continued understanding of how coproduction has been designed and executed across varied international SP models is important for framing engagement in practice for future SP arrangements and their evaluation. We anticipate this review will guide clients, communities, stakeholders, and policy makers in further developing SP practice within health care systems. Trial RegistrationOpen Science Framework Registries B8U4Z; https://osf.io/b8u4z International Registered Report Identifier (IRRID)DERR1-10.2196/57062

IntroductionSocial prescribing is defined as “a means for trusted individuals in clinical and community settings to identify that a person has nonmedical, health-related social needs and to subsequently connect them to nonclinical supports and services within the community by co-producing a social prescription—a nonmedical prescription, to improve health and well-being and to strengthen community connections.” Globally, there is growing interest in social prescribing as a holistic approach to health and well-being, with almost 30 countries involved in the social prescribing movement. In Canada, great strides are being made in social prescribing research, policy and practice, with all of this work being supported by the Canadian Institute for Social Prescribing.

IntroductionLa prescription sociale est « un moyen par lequel des professionnels de confiance en milieu clinique ou communautaire déterminent qu’une personne a des besoins sociaux liés à la santé qui ne sont pas d’ordre médical, et par lequel ils adressent cette personne à des services et à un soutien non cliniques au sein de la communauté, par l’élaboration conjointe d’une « prescription sociale », c’est-à-dire une prescription non médicale pour améliorer la santé et le bien-être de la personne et renforcer ses liens avec la communauté ». À l’échelle mondiale, la prescription sociale suscite un intérêt croissant en tant qu’approche holistique de la santé et du bien-être, et près de 30 pays sont impliqués dans le mouvement pour la prescription sociale. Au Canada, la recherche, les politiques et les pratiques en matière de prescription sociale progressent à grands pas avec le soutien de l’Institut canadien de prescription sociale.