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6 results on '"Le Gloahec, Tifenn"'

1. Validation and refinement of the clinical staging model in a French cohort of outpatient with schizophrenia (FACE-SZ)

Author

Andrianarisoa, Méja, Aouizerate, Bruno, Berna, Fabrice, Blanc, Olivier, Brunel, Lore, Bulzacka, Ewa, Capdevielle, Delphine, Chéreau-Boudet, Isabelle, Chesnoy-Servanin, Gabrielle, Danion, Jean-Marie, D'Amato, Thierry, Deloge, Arnaud, Delorme, Claire, Denizot, Hélène, Dorey, Jean-Michel, Dubertret, Caroline, Dubreucq, Julien, Faget, Catherine, Fluttaz, Cécile, Fond, Guillaume, Fonteneau, Sandrine, Gabayet, Franck, Giraud-Baro, Elisabeth, Hardy-Baylé, Marie-Christine, Lacelle, Delphine, Lançon, Christophe, Laouamri, Hakim, Leboyer, Marion, Le Gloahec, Tifenn, Le Strat, Yann, Llorca, Pierre-Michel, Mallet, Jasmina, Metairie, Emeline, Misdrahi, David, Passerieux, Christine, Peri, Pauline, Pires, Sylvie, Portalier, Céline, Rey, Romain, Roman, Céline, Sebilleau, Mathilde, Schandrin, Aurélie, Schneider, Priscille, Schurhoff, Franck, Tessier, Arnaud, Tronche, Anne-Marie, Urbach, Mathieu, Vaillant, Florence, Vehier, Aurélie, Vidailhet, Pierre, Vilà, Estelle, Yazbek, Hanan, Zinetti-Bertschy, Anna, Godin, Ophelia, Schürhoff, Frank, Boyer, Laurent, Myrtille, Andre, Andrianarisoa, Meja, Chereau, Isabelle, Lancon, Christophe, Leignier, Sylvain, Roux, Paul, and Costagliola, Dominique

Published
2019
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2. Benzodiazepine long-term administration is associated with impaired attention/working memory in schizophrenia: results from the national multicentre FACE-SZ data set

Author

Fond, Guillaume, Berna, F., Boyer, L., Godin, O., Brunel, L., Andrianarisoa, M., Aouizerate, B., Capdevielle, D., Chereau, I., Danion, J. M., Dubertret, C., Dubreucq, J., Faget, C., Gabayet, F., Le Gloahec, T., Llorca, P. M., Mallet, J., Misdrahi, D., Rey, R., Richieri, R., Passerieux, C., Portalier, C., Roux, P., Vehier, A., Yazbek, H., Schürhoff, F., Bulzacka, E., Andrianarisoa, Méja, Aouizerate, Bruno, Berna, Fabrice, Blanc, Olivier, Brunel, Lore, Bulzacka, Ewa, Capdevielle, Delphine, Chéreau-Boudet, Isabelle, Chesnoy-Servanin, Gabrielle, Danion, Jean-Marie, D’Amato, Thierry, Deloge, Arnaud, Delorme, Claire, Denizot, Hélène, Dorey, Jean-Michel, Dubertret, Caroline, Dubreucq, Julien, Faget, Catherine, Fluttaz, Cécile, Fond, Guillaume, Fonteneau, Sandrine, Gabayet, Franck, Giraud-Baro, Elisabeth, Hardy-Baylé, Marie-Christine, Lacelle, Delphine, Lançon, Christophe, Laouamri, Hakim, Leboyer, Marion, Le Gloahec, Tifenn, Le Strat, Yann, Llorca, Pierre-Michel, Mallet, Jasmina, Metairie, Emeline, Misdrahi, David, Offerlin-Meyer, Isabelle, Passerieux, Christine, Peri, Pauline, Pires, Sylvie, Portalier, Céline, Rey, Romain, Roman, Céline, Sebilleau, Mathilde, Schandrin, Aurélie, Schurhoff, Franck, Tessier, Arnaud, Tronche, Anne-Marie, Urbach, Mathieu, Vaillant, Florence, Vehier, Aurélie, Vidailhet, Pierre, Vilà, Estelle, Yazbek, Hanan, Zinetti-Bertschy, Anna, and The FACE-SZ (FondaMental Academic Centers of Expertise for Schizophrenia) group

Published
2017
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3. Validation and refinement of the clinical staging model in a French cohort of outpatient with schizophrenia (FACE-SZ)

Author

Godin, Ophelia, primary, Fond, Guillaume, additional, Bulzacka, Ewa, additional, Schürhoff, Frank, additional, Boyer, Laurent, additional, Myrtille, Andre, additional, Andrianarisoa, Meja, additional, Aouizerate, Bruno, additional, Berna, Fabrice, additional, Capdevielle, Delphine, additional, Chereau, Isabelle, additional, Dorey, Jean-Michel, additional, Dubertret, Caroline, additional, Dubreucq, Julien, additional, Faget, Catherine, additional, Lancon, Christophe, additional, Leignier, Sylvain, additional, Mallet, Jasmina, additional, Misdrahi, David, additional, Passerieux, Christine, additional, Rey, Romain, additional, Roux, Paul, additional, Vidailhet, Pierre, additional, Costagliola, Dominique, additional, Leboyer, Marion, additional, Llorca, Pierre-Michel, additional, Andrianarisoa, Méja, additional, Blanc, Olivier, additional, Brunel, Lore, additional, Chéreau-Boudet, Isabelle, additional, Chesnoy-Servanin, Gabrielle, additional, Danion, Jean-Marie, additional, D'Amato, Thierry, additional, Deloge, Arnaud, additional, Delorme, Claire, additional, Denizot, Hélène, additional, Fluttaz, Cécile, additional, Fonteneau, Sandrine, additional, Gabayet, Franck, additional, Giraud-Baro, Elisabeth, additional, Hardy-Baylé, Marie-Christine, additional, Lacelle, Delphine, additional, Lançon, Christophe, additional, Laouamri, Hakim, additional, Le Gloahec, Tifenn, additional, Le Strat, Yann, additional, Metairie, Emeline, additional, Peri, Pauline, additional, Pires, Sylvie, additional, Portalier, Céline, additional, Roman, Céline, additional, Sebilleau, Mathilde, additional, Schandrin, Aurélie, additional, Schneider, Priscille, additional, Schurhoff, Franck, additional, Tessier, Arnaud, additional, Tronche, Anne-Marie, additional, Urbach, Mathieu, additional, Vaillant, Florence, additional, Vehier, Aurélie, additional, Vilà, Estelle, additional, Yazbek, Hanan, additional, and Zinetti-Bertschy, Anna, additional

Published
2019
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4. Chronic Peripheral Inflammation is Associated With Cognitive Impairment ă in Schizophrenia: Results From the Multicentric FACE-SZ Dataset

Author

Bulzacka, Ewa, Boyer, Laurent, Schürhoff, Franck, Godin, Ophélia, Berna, Fabrice, Brunel, Lore, Andrianarisoa, Meja, Aouizerate, Bruno, Capdevielle, Delphine, Chereau-Boudet, Isabelle, Chesnoy-Servanin, Gabrielle, Danion, Jean-Marie, Dubertret, Caroline, Dubreucq, Julien, Faget, Catherine, Gabayet, Franck, Le Gloahec, Tifenn, Llorca, Pierre-Michel, Mallet, Jasmina, Misdrahi, David, Rey, Romain, Richieri, Raphaëlle, Passerieux, Christine, Roux, Paul, Yazbek, Hanan, Leboyer, Marion, Fond, Guillaume, Ctr, FACE-SZ FondaMental Acad, Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Fondation FondaMental [Créteil], Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Pôle de Psychiatrie et d’Addictologie, Hôpitaux Universitaires Henri-Mondor, Université Pierre et Marie Curie - Paris 6 (UPMC), INSERM Unit 708-Neuroepidemiology, Paris, France, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg (UNISTRA), Hôpital Charles Perrens, Neuropsychiatrie : recherche épidémiologique et clinique (PSNREC), Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Service Universitaire de Psychiatrie Adulte, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital La Colombière, Centres d'addictologies - Région Centre, CHU Clermont-Ferrand, Physiopathologie clinique et expérimentale de la schizophrénie, Université Louis Pasteur - Strasbourg I-IFR37-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Grenoble Alpes - UFR Médecine (UGA UFRM), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Laboratoire de santé publique évaluation des systèmes de soins et santé perçue, Département Universitaire de Psychiatrie - [Hôpital Sainte Marguerite - APHM] (Hôpitaux Sud), Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud )-Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU), Service de psychiatrie adulte - B, Laboratoire de recherches cliniques et en santé publique sur les handicaps psychique, cognitif et moteur (HANDIReSP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Unité Académique de Psychiatrie, Centre Hospitalier de Versailles André Mignot (CHV), Laboratoire de sciences cognitives et psycholinguistique (LSCP), Département d'Etudes Cognitives - ENS Paris (DEC), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École des hautes études en sciences sociales (EHESS)-Centre National de la Recherche Scientifique (CNRS), Interdisciplinary Institute for Neuroscience (IINS), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), INSERM U955, équipe 15, Service de psychiatrie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Hôpital Albert Chenevier-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Hôpital Albert Chenevier-Réseau de coopération scientifique en santé mentale, Fondation FondaMental [Créteil]-Fondation FondaMental [Créteil]-Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Centre hospitalier Charles Perrens [Bordeaux], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), École normale supérieure - Paris (ENS-PSL), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL)

Subjects
Adult, Male, medicine.medical_specialty, [SHS.PSY]Humanities and Social Sciences/Psychology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Semantic memory, Humans, Cognitive Dysfunction, Psychiatry, Inflammation, biology, Working memory, C-reactive protein, Cognitive flexibility, Neuropsychology, Cognition, Regular Article, Middle Aged, medicine.disease, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, Comorbidity, 030227 psychiatry, 3. Good health, Psychiatry and Mental health, C-Reactive Protein, Schizophrenia, quality, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, Chronic Disease, biology.protein, Female, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Psychology, 030217 neurology & neurosurgery
Abstract

International audience; Objectives: Inflammation, measured by abnormal blood C-reactive protein ă (CRP) level, has been described in schizophrenia (SZ), being ă inconsistently related to impaired cognitive functions. The aim of the ă present study is to investigate cognitive impairment associated with ă abnormal CRP levels in a large multi-centric sample of ă community-dwelling SZ patients, using a comprehensive neuropsychological ă battery. Method: Three hundred sixty-nine community-dwelling stable SZ ă subjects (76.2% men, mean age 32.7 y) were included and tested with a ă comprehensive battery of neuropsychological tests. Abnormal CRP level ă was defined as >3 mg/L. Results: Multiple factor analysis revealed that ă abnormal CRP levels, found in 104 patients (28.2%), were associated ă with impaired General Intellectual Ability and Abstract Reasoning (aOR = ă 0.56, 95% CI 0.35-0.90, P = .014), independently of age, sex, education ă level, psychotic symptomatology, treatments, and addiction ă comorbidities. Abnormal CRP levels were also associated with the decline ă of all components of working memory (respectively effect size [ ES] = ă 0.25, P = .033; ES = 0.27, P = .04; ES = 0.33, P = .006; and ES = 0.38, ă P = .004) and a wide range of other impaired cognitive functions, ă including memory (ES = 0.26, P = .026), learning abilities (ES = 0.28, P ă = .035), semantic memory (ES = 0.26, P = .026), mental flexibility (ES = ă 0.26, P = .044), visual attention (ES = 0.23, P = .004) and speed of ă processing (ES = 0.23, P = .043). Conclusion: Our results suggest that ă abnormal CRP level is associated with cognitive impairment in SZ. ă Evaluating the effectiveness of neuroprotective anti-inflammatory ă strategies is needed in order to prevent cognitive impairment in SZ.

Published
2016
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6. Chronic Peripheral Inflammation is Associated With Cognitive Impairment in Schizophrenia: Results From the Multicentric FACE-SZ Dataset.

Author

Bulzacka, Ewa, Boyer, Laurent, Schürhoff, Franck, Godin, Ophélia, Berna, Fabrice, Brunel, Lore, Andrianarisoa, Méja, Aouizerate, Bruno, Capdevielle, Delphine, Chéreau-Boudet, Isabelle, Chesnoy-Servanin, Gabrielle, Danion, Jean-Marie, Dubertret, Caroline, Dubreucq, Julien, Faget, Catherine, Gabayet, Franck, Le Gloahec, Tifenn, Llorca, Pierre-Michel, Mallet, Jasmina, and Misdrahi, David

Subjects
C-reactive protein, COGNITION disorders, CONFIDENCE intervals, FACTOR analysis, INFLAMMATION, SCHIZOPHRENIA, ODDS ratio
Published
2016
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