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151 results on '"Lee, Deokjong"'

12. In patients with late-life depression and cognitive decline, adding tDCS to cognitive training does not significantly affect depressive symptoms but shows potential benefits on cognition as measured by fMRI

Author

Ha, Junghee, primary, Fang, Yu, additional, Cron, Greg O., additional, Heo, Jaeseok, additional, Jung, Eunjin, additional, Lee, Deokjong, additional, Kim, Hyunjeong, additional, Kim, Eosu, additional, Park, Jin Young, additional, and Lee, Jin Hyung, additional

Published
2024
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17. Corrigendum to “Reduced grip strength potentially indicates depression: Investigating multicontinental databases” [J. Affect. Disord., 323 (2023) 426-434]

Author

Oh, Jae Won, primary, Kim, Sun Mi, additional, Lee, Deokjong, additional, Yon, Dong Keon, additional, Lee, Seung Won, additional, Smith, Lee, additional, Kostev, Karel, additional, Koyanagi, Ai, additional, Solmi, Marco, additional, Carvalho, Andre F., additional, Shin, Jae Il, additional, Son, Nak-Hoon, additional, and Lee, San, additional

Published
2023
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39. Structural and functional brain alterations associated with cancer‐associated cognitive decline in gastric cancer patients: A preliminary longitudinal neuroimaging study.

Author

Ahn, Jaeun, Lee, DeokJong, Jung, Young‐Chul, and Kim, Kyung Ran

Subjects
*STOMACH cancer, *FUNCTIONAL magnetic resonance imaging, *CANCER patients, *COGNITION disorders, *VOXEL-based morphometry
Abstract

Objective: Despite the clinical significance of cancer‐associated cognitive decline (CACD), no longitudinal study has evaluated CACD in gastric cancer patients. This preliminary study explored structural and functional neural changes of CACD in gastric cancer patients focusing on the effects of chemotherapy. Methods: 13 gastric cancer patients who received adjuvant chemotherapy (CTx+ group), 9 gastric cancer patients who did not receive adjuvant chemotherapy (CTx‐ group), and 10 healthy controls (HCs) were enrolled in this study. We performed self‐report questionnaires, neurocognitive tests, voxel‐based morphometry (VBM), and resting‐state functional magnetic resonance imaging (rsfMRI) analyses before and 3 months after chemotherapy. Results: Compared to the CTx‐ group, the CTx+ group exhibited statistically significant decrease in attention and executive function over time and dysfunction in delayed recognition performance. The results of the rsfMRI analysis showed a significant group‐by‐time interaction in the left hippocampus–anterior thalamus. However, no significant structural change was observed in the VBM analysis. Conclusion: To the best of our knowledge, this is the first longitudinal neuroimaging study on CACD in gastric cancer patients. Based on the results of our preliminary study, we suggest that the neuropathological processes and clinical presentation of CACD in gastric cancer patients is similar to those of patients associated with age‐related neurodegenerative disorders. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Dorsal striatal functional connectivity changes in Internet gaming disorder: A longitudinal magnetic resonance imaging study.

Author

Lee, Deokjong, Namkoong, Kee, Lee, Junghan, Jung, Young‐Chul, and Jung, Young-Chul

Subjects
*FUNCTIONAL connectivity, *VIDEO games, *DIAGNOSTIC imaging, *GRAY matter (Nerve tissue), *YEAR
Abstract

Internet gaming disorder (IGD) is a behavioral addiction involving excessive online game use despite negative psychosocial consequences. Unrestricted online gaming may lead to changes in striatal activity and the relationship between the striatum and other cortical regions. This study investigated structural and functional abnormalities involving the striatum through longitudinal follow-up magnetic resonance imaging (MRI) assessments. Eighteen young males with IGD (mean age: 23.8 ± 2.0 years) and 18 controls (mean age: 23.9 ± 2.7 years) were evaluated. Subjects were reassessed ≥1 year after the first visit (mean follow-up duration: 22.8 ± 6.7 months), using voxel-based morphometry and seed-based resting-state functional connectivity (FC) analyses in seed regions of the dorsal and ventral striatum. Subjects with IGD had smaller gray matter volume (GMV) in the anterior/middle cingulate cortex compared with controls during initial and follow-up assessments. They exhibited decreased FC between the left dorsal putamen and left medial prefrontal cortex (mPFC) compared with controls. They exhibited increased FC strength between the right dorsal putamen and right middle occipital gyrus (MOG) during follow-up. Subjects with IGD showed a significant correlation between changes in the dorsal putamen-MOG FC and gaming time per day. Young males with IGD showed an altered FC pattern in the dorsal striatum during follow-up. FC of the dorsal striatum in IGD increased in the mPFC and decreased in the MOG. These findings showed that IGD was accompanied by weakening of prefrontal control and strengthening of the sensorimotor network, suggesting that uncontrolled gaming may be related with functional neural changes in the dorsal striatum. [ABSTRACT FROM AUTHOR]

Published
2021
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