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4. Laser-driven jetting of nanoscale non-conducting liquid droplets via hollow optical fiber

Author

Yoo, Jinwon, Choi, Honggu, Suwal, Om Krishna, Lee, Sungrae, Jung, Woohyun, Kim, Sung Hyun, Lee, Sun-mi, Yoo, Kyung-hwa, Ryu, Wonhyoung, and Oh, Kyunghwan

Subjects
Physics - Applied Physics
Abstract

Along a single strand of micro-capillary optical waveguide, we achieved an efficient transfer of the light momentum onto the liquid contained there within, successfully atomizing it into nanoscale droplets. A hollow optical fiber (HOF), with a ring core and central air hole, was used to optically drive jetting of non-conducting transparent liquid of sub-pico liter volume, out of a surface-treated facet orifice, producing droplets ranging from nano to micrometer scale. These droplets were carried over the propagating light field forming a spherical cone, which were then deposited on a silica substrate in a Gaussian spatial distribution. The deposited patterns and sizes of individual droplets were characterized as a function of the laser power, irradiation time, and distance between the HOF and a substrate. This HOF based laser driven atomization technique obviates imperative electrode or aerial pressure requirements in prior methods, opening a new pathway to drastically scale down the form-factor of liquid jetting devices, and has a high potential to in-situ atomization and delivery of bio-medical non-conducting liquids in a microscopic environment, which was not possible in prior arts.

Published
2019

18. Effects of education on low-phosphate diet and phosphate binder intake to control serum phosphate among maintenance hemodialysis patients: A randomized controlled trial.

Author

Lim, Eunsoo, Hyun, Sunah, Lee, Jae Myeong, Kim, Seirhan, Lee, Min-Jeong, Lee, Sun-Mi, Oh, Ye-Sung, Park, Inwhee, Shin, Gyu-Tae, Kim, Heungsoo, Morisky, Donald E, and Jeong, Jong Cheol

Subjects
Compliance, Hemodialysis, Hyperphosphatemia, Phosphates
Abstract

Background:For phosphate control, patient education is essential due to the limited clearance of phosphate by dialysis. However, well-designed randomized controlled trials about dietary and phosphate binder education have been scarce. Methods:We enrolled maintenance hemodialysis patients and randomized them into an education group (n = 48) or a control group (n = 22). We assessed the patients' drug compliance and their knowledge about the phosphate binder using a questionnaire. Results:The primary goal was to increase the number of patients who reached a calcium-phosphorus product of lower than 55. In the education group, 36 (75.0%) patients achieved the primary goal, as compared with 16 (72.7%) in the control group (P = 0.430). The education increased the proportion of patients who properly took the phosphate binder (22.9% vs. 3.5%, P = 0.087), but not to statistical significance. Education did not affect the amount of dietary phosphate intake per body weight (education vs. control: -1.18 ± 3.54 vs. -0.88 ± 2.04 mg/kg, P = 0.851). However, the dietary phosphate-to-protein ratio tended to be lower in the education group (-0.64 ± 2.04 vs. 0.65 ± 3.55, P = 0.193). The education on phosphate restriction affected neither the Patient-Generated Subjective Global Assessment score (0.17 ± 4.58 vs. -0.86 ± 3.86, P = 0.363) nor the level of dietary protein intake (-0.03 ± 0.33 vs. -0.09 ± 0.18, P = 0.569). Conclusion:Education did not affect the calcium-phosphate product. Education on the proper timing of phosphate binder intake and the dietary phosphate-to-protein ratio showed marginal efficacy.

Published
2018

27. Influence of Surgery Preparation Time on Patient Outcomes.

Author

Jang, Hey-Jin and Lee, Sun-Mi

Subjects
*RISK assessment, *RESEARCH funding, *TASK performance, *BODY mass index, *CREATININE, *T-test (Statistics), *MULTIPLE regression analysis, *RESPIRATORY disease nursing, *PREOPERATIVE care, *TREATMENT effectiveness, *RETROSPECTIVE studies, *BLOOD urea nitrogen, *LACTATE dehydrogenase, *GLASGOW Coma Scale, *DESCRIPTIVE statistics, *CHI-squared test, *OPERATIVE surgery, *LONGITUDINAL method, *SURGICAL complications, *NURSING services administration, *CREATINE kinase, *ODDS ratio, *MEDICAL records, *ACQUISITION of data, *CONVALESCENCE, *INTENSIVE care units, *PATIENT satisfaction, *LENGTH of stay in hospitals, *COMPARATIVE studies, *CONFIDENCE intervals, *TIME, *OPERATING rooms, *SURGICAL site, *ANESTHESIA, *MECHANICAL ventilators, *APACHE (Disease classification system)
Abstract

Aims. This study aimed to analyze the effects of the surgery preparation time on patient outcomes. Background. Postoperative complications have a decisive effect on postoperative survival. The anesthesia time is a crucial determinant of such complications. Competent operating room nurses can shorten the surgery preparation time, which is the time from when anesthesia is first administered to the making of the surgical incision. The shortening of this preparation time can shorten the anesthesia time and may reduce postoperative complications. However, discussion of this preparation time is insufficient. Therefore, this study analyzed the effect of the surgery preparation time on patient outcomes. Methods. From electronic health records data, this retrospective cohort study used the data of 1,944 patients who had been immediately admitted to the ICU after their surgery between 2017 and 2020. The patients were divided into two groups: ≥30 minutes preparation time and <30 minutes preparation time groups. We performed chi-squared tests and t-tests to determine differences in preoperation, intraoperation, and postoperation characteristics of the patients and patient outcomes based on the surgery preparation time. Furthermore, we performed a multiple logistic regression by including 12 adjusted variables to determine the influence of the surgery preparation time on patient outcomes. Results. Among the 1,944 patients, 820 were in the ≥30 minutes preparation time group and 1,124 in the <30 minutes preparation time group. The multiple logistic regression analysis showed that the surgery preparation time affects alertness (OR = 1.44; 95% CI: [1.09, 1.90]), ventilator application (OR = 1.32; 95% CI: [1.03, 1.70]), and length of stay in the ICU (OR = 1.69; 95% CI [1.16, 2.47]). Conclusions. The surgery preparation time affects postoperative patient outcomes. The competence of operating room nurses is the most essential aspect of the surgery preparation time. Implications for Nursing Management. It is important to analyze operating room nurses' tasks, standardize the tasks, and educate nurses according to their experience level to reduce the surgery preparation time and improve patient outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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48. Data from Inhibition of 15-Hydroxyprostaglandin Dehydrogenase by Helicobacter pylori in Human Gastric Carcinogenesis

Author

Ryu, Yeon-Mi, primary, Myung, Seung-Jae, primary, Park, Young Soo, primary, Yang, Dong-Hoon, primary, Song, Ho June, primary, Jeong, Jin-Yong, primary, Lee, Sun Mi, primary, Song, Miyeoun, primary, Kim, Do Hoon, primary, Lee, Hyo-Jeong, primary, Park, Soo-Kyung, primary, Fink, Stephen P., primary, Markowitz, Sandy D., primary, Jung, Kee Wook, primary, Kim, Kyung-Jo, primary, Ye, Byong Duk, primary, Byeon, Jeong-Sik, primary, Jung, Hwoon-Yong, primary, Yang, Suk-Kyun, primary, and Kim, Jin-Ho, primary

Published
2023
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49. Supplementary Figure 4 from Inhibition of 15-Hydroxyprostaglandin Dehydrogenase by Helicobacter pylori in Human Gastric Carcinogenesis

Author

Ryu, Yeon-Mi, primary, Myung, Seung-Jae, primary, Park, Young Soo, primary, Yang, Dong-Hoon, primary, Song, Ho June, primary, Jeong, Jin-Yong, primary, Lee, Sun Mi, primary, Song, Miyeoun, primary, Kim, Do Hoon, primary, Lee, Hyo-Jeong, primary, Park, Soo-Kyung, primary, Fink, Stephen P., primary, Markowitz, Sandy D., primary, Jung, Kee Wook, primary, Kim, Kyung-Jo, primary, Ye, Byong Duk, primary, Byeon, Jeong-Sik, primary, Jung, Hwoon-Yong, primary, Yang, Suk-Kyun, primary, and Kim, Jin-Ho, primary

Published
2023
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50. Supplementary Figure 2 from Inhibition of 15-Hydroxyprostaglandin Dehydrogenase by Helicobacter pylori in Human Gastric Carcinogenesis

Author

Ryu, Yeon-Mi, primary, Myung, Seung-Jae, primary, Park, Young Soo, primary, Yang, Dong-Hoon, primary, Song, Ho June, primary, Jeong, Jin-Yong, primary, Lee, Sun Mi, primary, Song, Miyeoun, primary, Kim, Do Hoon, primary, Lee, Hyo-Jeong, primary, Park, Soo-Kyung, primary, Fink, Stephen P., primary, Markowitz, Sandy D., primary, Jung, Kee Wook, primary, Kim, Kyung-Jo, primary, Ye, Byong Duk, primary, Byeon, Jeong-Sik, primary, Jung, Hwoon-Yong, primary, Yang, Suk-Kyun, primary, and Kim, Jin-Ho, primary

Published
2023
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