Search

Your search keyword '"Lee, Yann-Leei L."' showing total 18 results
Start Over Author "Lee, Yann-Leei L."
18 results on '"Lee, Yann-Leei L."'

4. Admission Medication Reconciliation Discrepancies in Trauma Patients: Consistent Nursing Care May Not Be the Answer

Author

Gautreaux, Corinne E., primary, Robinson, Thomas W., additional, Dunbar, Elisabeth G., additional, Lee, Yann-Leei L., additional, Mbaka, Maryann, additional, Kinnard, Christopher M., additional, Bright, Andrew C., additional, Williams, Ashley Y., additional, Polite, Nathan M., additional, Capasso, Thomas J., additional, Simmons, Jon D., additional, and Butts, C. Caleb, additional

Published
2024
Full Text
View/download PDF

5. Social Determinants of Health Impact Physical Recovery After Blunt Injury

Author

Cockrell, Benjamin E., primary, Haiflich, Andrew N., additional, Lee, Yann-Leei L., additional, Kinnard, Christopher M., additional, Butts, Charles C., additional, Polite, Nathan M., additional, Mbaka, Maryann I., additional, Bright, Andrew C., additional, Simmons, Jon D., additional, and Williams, Ashley Y., additional

Published
2023
Full Text
View/download PDF

8. Defining Pathogen and Susceptibility Patterns for Early Versus Late Ventilator Associated Pneumonia in Trauma Patients to Guide Empiric Treatment Decisions

Author

Alexander, Kaitlin M., Davis, S. Noelle, Butts, C. Caleb, Morgan, John, Croft, Leah K., Lee, Yann-leei L., Kinnard, Christopher M., Polite, Nathan M., Mbaka, Maryann I., Williams, Ashley Y., Barrington, Robert A., Audia, Jonathon P., and Simmons, Jon D.

Abstract

Introduction Studies have demonstrated that trauma patients with early-ventilator associated pneumonia (early-VAP, < 7 days) have decreased risk of methicillin-resistant Staphylococcus aureus(MRSA) and Pseudomonas aeruginosainfections. We hypothesize that routinely using broad-spectrum antibiotics is unnecessary to treat trauma patients with the diagnosis of early-VAP.Methods This retrospective cohort study included adult trauma patients with the diagnosis of VAP. The primary outcome was the presence of MRSA and/or P. aeruginosain patients with early- and late-VAP. Secondary outcomes included the bacterial susceptibility of pathogens to methicillin, ampicillin/sulbactam, ceftriaxone, piperacillin/tazobactam, and cefepime. Intensive care unit (ICU) and hospital length of stay (LOS), ventilator-free days, and in-hospital mortality were also collected.Results 164 patients met inclusion criteria, and 208 organisms (n = 90 early vs n = 118 late) were identified by respiratory culture. The incidence of MRSA and P. aeruginosain early-VAP was 7.7% (7/90) and 5.6% (5/90), respectively. The susceptibility of bacteria causing early-VAP to ampicillin/sulbactam and ceftriaxone was 73.3% (66/90) and 83.3% (75/90), respectively. Ventilator-free days at 30 days was similar between groups (P= .649). Patients with late-VAP spent more time in the ICU (P= .040); however, in-hospital mortality was higher in the early-VAP group (P= .012).Conclusions Ampicillin/sulbactam or ceftriaxone monotherapy did not provide reliable broad-spectrum coverage for early-VAP in our cohort. These findings highlight the importance of each institution performing a similar analysis to ensure adequate initial treatment of VAP.

Published
2023
Full Text
View/download PDF

9. Defining Pathogen and Susceptibility Patterns for Early Versus Late Ventilator Associated Pneumonia in Trauma Patients to Guide Empiric Treatment Decisions

Author

Alexander, Kaitlin M., primary, Davis, S. Noelle, additional, Butts, C. Caleb, additional, Morgan, John, additional, Croft, Leah K., additional, Lee, Yann-leei L., additional, Kinnard, Christopher M., additional, Polite, Nathan M., additional, Mbaka, Maryann I., additional, Williams, Ashley Y., additional, Barrington, Robert A., additional, Audia, Jonathon P., additional, and Simmons, Jon D., additional

Published
2022
Full Text
View/download PDF

11. The Relationship between Serum Sodium, Serum Osmolality, and Intracranial Pressure in Patients with Traumatic Brain Injury Treated with Hyperosmolar Therapy

Author

Farley, Paige, primary, Salisbury, Daniel, additional, Murfee, John R, additional, Buckley, Colin T, additional, Taylor, Catherine N, additional, Doll, Alissa, additional, Polite, Nathan M, additional, Mbaka, Maryann I, additional, Kinnard, Christopher M, additional, Butts, Charles Caleb, additional, Simmons, Jon D, additional, and Lee, Yann‐Leei L, additional

Published
2021
Full Text
View/download PDF

12. Impact of the State-mandated Stay-at-home Order for the COVID-19 Pandemic on an Academic Level I Trauma Center with a Large Rural Catchment Area

Author

Simmons, Kay A., primary, Roberts, Morgan E., additional, Ray, Gannon J., additional, Bright, Andrew C., additional, Kinnard, Christopher M., additional, Lee, Yann-Leei L., additional, Mbaka, Maryann I., additional, Polite, Nate, additional, Simmons, Jon D., additional, and Butts, Charles, additional

Published
2021
Full Text
View/download PDF

15. Shock

Author

Bright, Andrew C, primary, Lee, Yann-Leei L, primary, and Simmons, Jon D, primary

Published
2019
Full Text
View/download PDF

16. The Relationship between Serum Sodium, Serum Osmolality, and Intracranial Pressure in Patients with Traumatic Brain Injury Treated with Hyperosmolar Therapy

Author

Farley, Paige, Salisbury, Daniel, Murfee, John R, Buckley, Colin T, Taylor, Catherine N, Doll, Alissa, Polite, Nathan M, Mbaka, Maryann I, Kinnard, Christopher M, Butts, Charles Caleb, Simmons, Jon D, and Lee, Yann‐Leei L

Abstract

Background Treatment of elevated intracranial pressure (ICP) in traumatic brain injury (TBI) is controversial. Hyperosmolar therapy is used to prevent cerebral edema in these patients. Many intensivists measure direct correlates of these agents—serum sodium and osmolality. We seek to provide context on the utility of using these measures to estimate ICP in TBI patients.Materials and Methods Patients admitted with TBI who required ICP monitoring from 2008 to 2012 were included. Intracranial pressure, serum sodium, and serum osmolality were assessed prior to hyperosmotic therapy then at 6, 12, 18, 24, 48, and 72 hours after admission. A linear regression was performed on sodium, osmolality, and ICP at baseline and serum sodium and osmolality that corresponded with ICP for 6-72-hour time points.Results 136 patients were identified. Patients with initial measures were included in the baseline analysis (n = 29). Patients who underwent a craniectomy were excluded from the 6-72-hour analysis (n = 53). Initial ICP and serum sodium were not significantly correlated (R2 .00367, P= .696). Initial ICP and serum osmolality were not significantly correlated (R2 .00734, P= .665). Intracranial pressure and serum sodium 6-72 hours after presentation were poorly correlated (R2 .104, P< .0001), as were ICP and serum osmolality at 6-72 hours after presentation (R2 .116, P< .0001).Discussion Our results indicate initial ICP is not correlated with serum sodium or osmolality suggesting these are not useful initial clinical markers for ICP estimation. The association between ICP and serum sodium and osmolality after hyperosmolar therapy was poor, thus may not be useful as surrogates for direct ICP measurements.

Published
2022
Full Text
View/download PDF

17. Potential contribution of mitochondrial DNA damage associated molecular patterns in transfusion products to the development of acute respiratory distress syndrome after multiple transfusions

Author

Simmons, Jon D., primary, Lee, Yann-leei L., additional, Pastukh, Viktor M., additional, Capley, Gina, additional, Muscat, Cherry A., additional, Muscat, David C., additional, Marshall, Michael L., additional, Brevard, Sidney B., additional, and Gillespie, Mark N., additional

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results