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10 results on '"Lehtimäki, Jarmo"'

3. Attenuation of Positive Valence in Ratings of Affective Sounds by Tinnitus Patients

Author

Szibor, Annett, Lehtimäki, Jarmo, Ylikoski, Jukka, Aarnisalo, Antti A., Mäkitie, Antti, Hyvärinen, Petteri, Szibor, Annett, Lehtimäki, Jarmo, Ylikoski, Jukka, Aarnisalo, Antti A., Mäkitie, Antti, and Hyvärinen, Petteri

Abstract

Affective processing appears to be altered in tinnitus, and the condition is to a large extent characterized by the emotional reaction to the phantom sound. Psychophysiological models of tinnitus and supporting brain imaging studies have suggested a role for the limbic system in the emergence and maintenance of tinnitus. It is not clear whether the tinnitus-related changes in these systems are specific for tinnitus only, or whether they affect emotional processing more generally. In this study, we aimed to quantify possible deviations in affective processing in tinnitus patients by behavioral and physiological measures. Tinnitus patients rated the valence and arousal of sounds from the International Affective Digitized Sounds database. Sounds were chosen based on the normative valence ratings, that is, negative, neutral, or positive. The individual autonomic response was measured simultaneously with pupillometry. We found that the subjective ratings of the sounds by tinnitus patients differed significantly from the normative ratings. The difference was most pronounced for positive sounds, where sounds were rated lower on both valence and arousal scales. Negative and neutral sounds were rated differently only for arousal. Pupil measurements paralleled the behavioral results, showing a dampened response to positive sounds. Taken together, our findings suggest that affective processing is altered in tinnitus patients. The results are in line with earlier studies in depressed patients, which have provided evidence in favor of the so-called positive attenuation hypothesis of depression. Thus, the current results highlight the close link between tinnitus and depression.

Published
2018

8. Hearing disorder from music; a neglected dysfunction.

Author

Szibor, Annett, Hyvärinen, Petteri, Lehtimäki, Jarmo, Pirvola, Ulla, Ylikoski, Matti, Mäkitie, Antti, Aarnisalo, Antti, and Ylikoski, Jukka

Subjects
NOISE-induced deafness, AUDIOMETRY, HEARING disorders, HAIR cells, MUSIC, PSYCHOPHYSIOLOGY, SLEEP disorders, TINNITUS, HYPERACUSIS, VISUAL analog scale, ACUTE diseases, DIAGNOSIS
Abstract

Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
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10. Transcutaneous vagus nerve stimulation in tinnitus: a pilot study.

Author

Lehtimäki, Jarmo, Hyvärinen, Petteri, Ylikoski, Matti, Bergholm, Mikael, Mäkelä, Jyrki P., Aarnisalo, Antti, Pirvola, Ulla, Mäkitie, Antti, and Ylikoski, Jukka

Subjects
*NEURAL stimulation, *TINNITUS treatment, *QUESTIONNAIRES, *VAGUS nerve, *PILOT projects, *DISABILITIES, *DESCRIPTIVE statistics
Abstract

Conclusions: This pilot study shows that transcutaneous vagus nerve stimulation (tVNS), if combined with sound therapy (ST), reduces the seventy of tinnitus and tinnitus-associated distress. Our maguetoencephalography (MEG) results show that auditory cortical activation can be modulated by the application of tVNS. Thus, tVNS might offer a new avenue to treat tinnitus and tinnitus-associated distress. Objectives: Recent studies suggest that tinnitus can be improved by tailored ST or by VNS plus ST. Our aims were to study whether tVNS has therapeutic effects on patients with tinnitus and, additionally, if tVNS has effects on acoustically evoked neuronal activity of the auditory cortex. Methods: The clinical efficacy was studied by a short-term tVNS plus ST trial in 10 patients with tinnitus using disease-specific and general well-being questionnaires, tVNS was delivered to the left tragus. The acute effects of tVNS were evaluated in eight patients in the MEG study in which the Nlm response was analyzed in terms of source level amplitude and latency in the presence or absence of tVNS. Results: The treatment with tVNS plus ST produced improved mood and decreased tinnitus handicap scores, indicating reduced tinnitus seventy. The application of tVNS decreased the amplitude of auditory N1m responses in both hemispheres. [ABSTRACT FROM AUTHOR]

Published
2013
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