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585 results on '"Leite, Fabio"'

2. High free sugars, insulin resistance, and low socioeconomic indicators: the hubs in the complex network of non-communicable diseases in adolescents

Author

Alves-Costa, Silas, de Souza, Bruno Feres, Rodrigues, Francisco Aparecido, Ferraro, Alexandre Archanjo, Nascimento, Gustavo G., Leite, Fabio R. M., Ladeira, Lorena Lúcia Costa, Batista, Rosângela Fernandes Lucena, Thomaz, Erika Bárbara Abreu Fonseca, Alves, Claudia Maria Coelho, and Ribeiro, Cecilia Claudia Costa

Published
2024
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3. Federated and distributed learning applications for electronic health records and structured medical data: A scoping review

Author

Li, Siqi, Liu, Pinyan, Nascimento, Gustavo G., Wang, Xinru, Leite, Fabio Renato Manzolli, Chakraborty, Bibhas, Hong, Chuan, Ning, Yilin, Xie, Feng, Teo, Zhen Ling, Ting, Daniel Shu Wei, Haddadi, Hamed, Ong, Marcus Eng Hock, Peres, Marco Aurélio, and Liu, Nan

Subjects
Computer Science - Machine Learning, Computer Science - Artificial Intelligence
Abstract

Federated learning (FL) has gained popularity in clinical research in recent years to facilitate privacy-preserving collaboration. Structured data, one of the most prevalent forms of clinical data, has experienced significant growth in volume concurrently, notably with the widespread adoption of electronic health records in clinical practice. This review examines FL applications on structured medical data, identifies contemporary limitations and discusses potential innovations. We searched five databases, SCOPUS, MEDLINE, Web of Science, Embase, and CINAHL, to identify articles that applied FL to structured medical data and reported results following the PRISMA guidelines. Each selected publication was evaluated from three primary perspectives, including data quality, modeling strategies, and FL frameworks. Out of the 1160 papers screened, 34 met the inclusion criteria, with each article consisting of one or more studies that used FL to handle structured clinical/medical data. Of these, 24 utilized data acquired from electronic health records, with clinical predictions and association studies being the most common clinical research tasks that FL was applied to. Only one article exclusively explored the vertical FL setting, while the remaining 33 explored the horizontal FL setting, with only 14 discussing comparisons between single-site (local) and FL (global) analysis. The existing FL applications on structured medical data lack sufficient evaluations of clinically meaningful benefits, particularly when compared to single-site analyses. Therefore, it is crucial for future FL applications to prioritize clinical motivations and develop designs and methodologies that can effectively support and aid clinical practice and research.

Published
2023

10. Robust diversity in cognitive science

Author

Vandekerckhove, Joachim, White, Corey, Trueblood, Jennifer, Rouder, Jeffrey, Matzke, Dora, Leite, Fabio P, Etz, Alexander, Donkin, Chris, Devezer, Berna, Criss, Amy H, and Lee, Michael David

Abstract

The target article on robust modeling (Lee et al.) generated a lot of commentary. In this reply, we discuss some of the common themes in the commentaries; some are simple points of agreement while others are extensions of a practical or abstract nature. We also address a small number of disagreements or confusions.

Published
2019

21. DETECTION OF Toxocara canis DNA IN TISSUES OF EXPERIMENTALLY INFECTED MICE

Author

Moura, Micaele Quintana de, primary, Macedo, Marcia Raquel Pegoraro de, additional, Terto, Wesley Douglas da Silva, additional, Avila, Luciana Farias da Costa, additional, Leite, Fabio Pereira Leivas, additional, Scaini, Carlos Jaime, additional, Pinto, Natália Berne, additional, Capella, Gabriela de Almeida, additional, Strothmann, Adriane Leites, additional, Villela, Marcos Marreiro, additional, and Berne, Maria Elisabeth Aires, additional

Published
2022
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32. Dynamic Risk Assessment Enabling Automated Interventions for Medical Cyber-Physical Systems

Author

Leite, Fábio L., Jr., Schneider, Daniel, Adler, Rasmus, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Romanovsky, Alexander, editor, Troubitsyna, Elena, editor, and Bitsch, Friedemann, editor

Published
2019
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36. Incidence, mortality and survival rates of lip, oral cavity and salivary glands cancers in Singapore: A half‐century time trend analysis (1968–2017).

Author

Peres, Marco A., Li, Huihua, Nascimento, Gustavo G., and Leite, Fabio R. M.

Subjects
MORTALITY, MOUTH tumors, STATISTICAL significance, SEX distribution, SALIVARY gland tumors, AGE distribution, DESCRIPTIVE statistics, LIP tumors, KAPLAN-Meier estimator, SURVIVAL analysis (Biometry), CONFIDENCE intervals, DATA analysis software, OVERALL survival, TIME, REGRESSION analysis, DISEASE incidence
Abstract

Objectives: To examine trends in incidence and mortality and evaluate overall survival (OS) of oral cancer in Singapore between 1968 and 2017. Methods: All diagnosed oral cancers by anatomical sites and population size were extracted from the Singapore Cancer Registry and the Department of Statistics Singapore. The trend of age‐standardized incidence rate (ASIR) and mortality rate (ASMR) (per 100 000 person‐years) of the lip, oral cavity and salivary gland cancers were evaluated by Prais‐Winsten regressions for each ethnicity and gender. Kaplan–Meier curves were performed to evaluate the OS by anatomical sites in each age group by ethnicity and sex. Results: Overall, 49, 3494 and 1066 people were diagnosed, and 28, 2310 and 476 died from lip, oral cavity and salivary gland cancers, respectively. The oral cavity cancer ASIR and ASMR reduced from 3.07 (1968–1972) to 2.01(2008–2012) and from 2.06 (1978–1982) to 1.21 (2013–2017) per 100 000 person‐years, respectively, with both highest in Indians throughout the whole period. Male:Female ratio ranged from 3.43 (1973–1977) to 1.75 (2013–2017) and from 3.41 (1978–1982) to 2.40 (2013–2017) for ASIR and ASMR, respectively. However, both salivary gland cancer ASIR and ASMR increased from 0.50 (1968–1972) to 0.80 (2008–2012) and from 0.18 (1968–1982) to 0.42 (1988–1992) per 100 000 person‐years, respectively, with both higher in males since 1993. Oral cavity cancer ASIR decreased for males aged ≥60, and Indian females ≥25, but increased among Chinese females aged ≥60. Oral cavity cancer ASMR decreased among Chinese aged 25–59, and among Malay males and Indian females. Salivary gland cancer ASIR increased among Chinese males aged ≥60 and Malay males aged 25–59; while ASMR increased among Chinese males aged ≥60. The median OS for oral cavity, lip and salivary gland cancers were 3.0, 9.3 and 18.1 years, respectively, with females surviving longer than males. Conclusions: Singapore has experienced a decline in the incidence and mortality of lip, oral cancer, an increase in in the incidence and mortality of salivary gland cancer, with an increase in the median overall survival rate. Monitoring the magnitude of oral cancer burden and the demographic, and temporal variations is necessary for tailoring health planning and setting priorities for future clinical care and research. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Oral and systemic health in Singapore: Revisiting the past to define the future.

Author

Nascimento, Gustavo G., Balan, Preethi, Alves‐Costa, Silas, Bitencourt, Fernando Valentim, Kalhan, Ashish C., and Leite, Fabio R. M.

Subjects
MEDICAL information storage & retrieval systems, PNEUMONIA, HEALTH status indicators, CROHN'S disease, GINGIVITIS, PERIODONTAL disease, HUMAN microbiota, SYSTEMATIC reviews, MEDLINE, TOOTH eruption, MASTICATION, CHILD development, ONLINE information services, DENTAL caries, ORAL health, DIABETES, COGNITION
Abstract

Objectives: This study aimed to identify studies exploring oral and systemic conditions using Singapore data. Methods: Studies were searched using the databases PubMed, Embase and Web of Science, with no publication date or language restrictions. Studies analysing Singaporean data were included in this review. Results: Six domains were identified: pregnancy and gingivitis; tooth eruption, dental caries and early‐life factors; Crohn's disease and oral microbiome; diabetes and periodontal diseases; number of teeth, chewing ability and cognitive status; and oral health and pneumonia. Using data from Singapore, oral‐systemic studies have prompted reflections on the aetiopathogenesis of oral disorders, such as common causes connecting oral and systemic chronic conditions. Moreover, it is speculated whether oral conditions could be used as a marker to predict future systemic diseases or whether early‐life factors could affect the development of oral and systemic immune responses. Conclusions: While Singapore provides opportunities to explore challenges connected to healthy ageing, it also explores health development in many stages of life. Singapore has been prioritizing investigations on a healthier life, and new initiatives are paving the way for oral health research across the lifespan. [ABSTRACT FROM AUTHOR]

Published
2024
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38. Raman Spectroscopy on Free-Base Meso-tetra(4-pyridyl) Porphyrin under Conditions of Low Temperature and High Hydrostatic Pressure.

Author

dos Reis, Jhon Rewllyson Torres, Leite, Fabio Furtado, Sharma, Keshav, Ribeiro, Guilherme Almeida Silva, Silva, Welesson Henrique Natanael, Batista, Alzir Azevedo, Paschoal, Alexandre Rocha, Paraguassu, Waldeci, Mazzoni, Mario, Barbosa Neto, Newton Martins, and Araujo, Paulo Trindade

Subjects
*HYDROSTATIC pressure, *RAMAN spectroscopy, *LOW temperatures, *PORPHYRINS, *HIGH temperatures, *METALLOPORPHYRINS
Abstract

We present a Raman spectroscopy study of the vibrational properties of free-base meso-tetra(4-pyridyl) porphyrin polycrystals under various temperature and hydrostatic pressure conditions. The combination of experimental results and Density Functional Theory (DFT) calculations allows us to assign most of the observed Raman bands. The modifications in the Raman spectra when excited with 488   n m and 532   n m laser lights indicate that a resonance effect in the Q y band is taking place. The pressure-dependent results show that the resonance conditions change with increasing pressure, probably due to the shift of the electronic transitions. The temperature-dependent results show that the relative intensities of the Raman modes change at low temperatures, while no frequency shifts are observed. The experimental and theoretical analysis presented here suggest that these molecules are well represented by the C 2 v point symmetry group. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Dynamic Risk Management for Cooperative Autonomous Medical Cyber-Physical Systems

Author

Leite, Fábio L., Jr., Schneider, Daniel, Adler, Rasmus, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Gallina, Barbara, editor, Skavhaug, Amund, editor, Schoitsch, Erwin, editor, and Bitsch, Friedemann, editor

Published
2018
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44. Safety Assurance for Autonomous and Collaborative Medical Cyber-Physical Systems

Author

Leite, Fabio L., Jr., Adler, Rasmus, Feth, Patrik, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Tonetta, Stefano, editor, Schoitsch, Erwin, editor, and Bitsch, Friedemann, editor

Published
2017
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46. Federated and distributed learning applications for electronic health records and structured medical data: a scoping review

Author

Li, Siqi, primary, Liu, Pinyan, additional, Nascimento, Gustavo G, additional, Wang, Xinru, additional, Leite, Fabio Renato Manzolli, additional, Chakraborty, Bibhas, additional, Hong, Chuan, additional, Ning, Yilin, additional, Xie, Feng, additional, Teo, Zhen Ling, additional, Ting, Daniel Shu Wei, additional, Haddadi, Hamed, additional, Ong, Marcus Eng Hock, additional, Peres, Marco Aurélio, additional, and Liu, Nan, additional

Published
2023
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