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2. Atmospheric and Surface Processes, and Feedback Mechanisms Determining Arctic Amplification: A Review of First Results and Prospects of the (AC)3 Project

Author

Wendisch, M., Brückner, M., Crewell, Susanne, Ehrlich, A., Notholt, J., Lüpkes, C., Macke, A., Burrows, J. P., Rinke, A., Quaas, J., Maturilli, M., Schemann, V., Shupe, M. D., Akansu, E. F., Barrientos-Velasco, C., Bärfuss, K., Blechschmidt, A.-M., Block, K., Bougoudis, I., Bozem, H., Böckmann, C., Bracher, A., Bresson, H., Bretschneider, L., Buschmann, M., Chechin, D. G., Chylik, J., Dahlke, S., Deneke, H., Dethloff, K., Donth, T., Dorn, W., Dupuy, R., Ebell, K., Egerer, U., Engelmann, R., Eppers, O., Gerdes, R., Gierens, R., Gorodetskaya, I. V., Gottschalk, M., Griesche, H., Gryanik, V. M., Handorf, D., Harm-Altstädter, B., Hartmann, J., Hartmann, M., Heinold, B., Herber, A., Herrmann, H., Heygster, G., Höschel, I., Hofmann, Z., Hölemann, J., Hünerbein, A., Jafariserajehlou, S., Jäkel, E., Jacobi, C., Janout, M., Jansen, F., Jourdan, O., Jurányi, Z., Kalesse-Los, H., Kanzow, T., Käthner, R., Kliesch, L. L., Klingebiel, M., Knudsen, E. M., Kovács, T., Körtke, W., Krampe, D., Kretzschmar, J., Kreyling, D., Kulla, B., Kunkel, D., Lampert, A., Lauer, M., Lelli, L., von Lerber, A., Linke, O., Löhnert, U., Lonardi, M., Losa, S. N., Losch, M., Maahn, M., Mech, M., Mei, L., Mertes, S., Metzner, E., Mewes, D., Michaelis, J., Mioche, G., Moser, Manuel, Nakoudi, K., Neggers, R., Neuber, R., Nomokonova, T., Oelker, J., Papakonstantinou-Presvelou, I., Pätzold, F., Pefanis, V., Pohl, C., van Pinxteren, M., Radovan, A., Rhein, M., Rex, Markus, Richter, A., Risse, N., Ritter, C., Rostosky, P., Rozanov, V. V., Ruiz Donoso, E., Saavedra-Garfias, P., Salzmann, M., Schacht, J., Schäfer, M., Schneider, J., Schnierstein, N., Seifert, P., Seo, S., Siebert, H., Soppa, M. A., Spreen, G., Stachlewska, I. S., Stapf, J., Stratmann, F., Tegen, I., Viceto, C., Voigt, Christiane, Vountas, M., Walbröl, A., Walter, M., Wehner, B., Wex, H., Willmes, S., Zanatta, M., Zeppenfeld, S., Laboratoire de Météorologie Physique (LaMP), and Institut national des sciences de l'Univers (INSU - CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS)

Subjects
Atmospheric Science, [SDU]Sciences of the Universe [physics], clouds, Arctic amplification
Abstract

Mechanisms behind the phenomenon of Arctic amplification are widely discussed. To contribute to this debate, the (AC)3 project was established in 2016 (www.ac3-tr.de/). It comprises modeling and data analysis efforts as well as observational elements. The project has assembled a wealth of ground-based, airborne, shipborne, and satellite data of physical, chemical, and meteorological properties of the Arctic atmosphere, cryosphere, and upper ocean that are available for the Arctic climate research community. Short-term changes and indications of long-term trends in Arctic climate parameters have been detected using existing and new data. For example, a distinct atmospheric moistening, an increase of regional storm activities, an amplified winter warming in the Svalbard and North Pole regions, and a decrease of sea ice thickness in the Fram Strait and of snow depth on sea ice have been identified. A positive trend of tropospheric bromine monoxide (BrO) column densities during polar spring was verified. Local marine/biogenic sources for cloud condensation nuclei and ice nucleating particles were found. Atmospheric–ocean and radiative transfer models were advanced by applying new parameterizations of surface albedo, cloud droplet activation, convective plumes and related processes over leads, and turbulent transfer coefficients for stable surface layers. Four modes of the surface radiative energy budget were explored and reproduced by simulations. To advance the future synthesis of the results, cross-cutting activities are being developed aiming to answer key questions in four focus areas: lapse rate feedback, surface processes, Arctic mixed-phase clouds, and airmass transport and transformation.

Published
2023
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3. Atmospheric and Surface Processes, and Feedback Mechanisms Determining Arctic Amplification: A Review of First Results and Prospects of the (AC)3 Project

Author

Wendisch, M, Brückner, M, Crewell, S, Ehrlich, A, Notholt, J, Lüpkes, C, Macke, A, Burrows, JP, Rinke, A, Quaas, J, Maturilli, M, Schemann, V, Shupe, MD, Akansu, EF, Barrientos-Velasco, C, Bärfuss, K, Blechschmidt, A-M, Block, K, Bougoudis, I, Bozem, H, Böckmann, C, Bracher, A, Bresson, H, Bretschneider, L, Buschmann, M, Chechin, DG, Chylik, J, Dahlke, S, Deneke, H, Dethloff, K, Donth, T, Dorn, W, Dupuy, R, Ebell, K, Egerer, U, Engelmann, R, Eppers, O, Gerdes, R, Gierens, R, Gorodetskaya, IV, Gottschalk, M, Griesche, H, Gryanik, VM, Handorf, D, Harm-Altstädter, B, Hartmann, J, Hartmann, M, Heinold, B, Herber, A, Herrmann, H, Heygster, G, Höschel, I, Hofmann, Z, Hölemann, J, Hünerbein, A, Jafariserajehlou, S, Jäkel, E, Jacobi, C, Janout, M, Jansen, F, Jourdan, O, Jurányi, Z, Kalesse-Los, H, Kanzow, T, Käthner, R, Kliesch, LL, Klingebiel, M, Knudsen, EM, Kovács, T, Körtke, W, Krampe, D, Kretzschmar, J, Kreyling, D, Kulla, B, Kunkel, D, Lampert, A, Lauer, M, Lelli, L, von Lerber, A, Linke, O, Löhnert, U, Lonardi, M, Losa, SN, Losch, M, Maahn, M, Mech, M, Mei, L, Mertes, S, Metzner, E, Mewes, D, Michaelis, J, Mioche, G, Moser, M, Nakoudi, K, Neggers, R, Neuber, R, Nomokonova, T, Oelker, J, Papakonstantinou-Presvelou, I, Pätzold, F, Pefanis, V, Pohl, C, van Pinxteren, M, Radovan, A, Rhein, M, Rex, M, Richter, A, Risse, N, Ritter, C, Rostosky, P, Rozanov, VV, Donoso, E Ruiz, Saavedra Garfias, P, Salzmann, M, Schacht, J, Schäfer, M, Schneider, J, Schnierstein, N, Seifert, P, Seo, S, Siebert, H, Soppa, MA, Spreen, G, Stachlewska, IS, Stapf, J, Stratmann, F, Tegen, I, Viceto, C, Voigt, C, Vountas, M, Walbröl, A, Walter, M, Wehner, B, Wex, H, Willmes, S, Zanatta, M, Zeppenfeld, S, Wendisch, M, Brückner, M, Crewell, S, Ehrlich, A, Notholt, J, Lüpkes, C, Macke, A, Burrows, JP, Rinke, A, Quaas, J, Maturilli, M, Schemann, V, Shupe, MD, Akansu, EF, Barrientos-Velasco, C, Bärfuss, K, Blechschmidt, A-M, Block, K, Bougoudis, I, Bozem, H, Böckmann, C, Bracher, A, Bresson, H, Bretschneider, L, Buschmann, M, Chechin, DG, Chylik, J, Dahlke, S, Deneke, H, Dethloff, K, Donth, T, Dorn, W, Dupuy, R, Ebell, K, Egerer, U, Engelmann, R, Eppers, O, Gerdes, R, Gierens, R, Gorodetskaya, IV, Gottschalk, M, Griesche, H, Gryanik, VM, Handorf, D, Harm-Altstädter, B, Hartmann, J, Hartmann, M, Heinold, B, Herber, A, Herrmann, H, Heygster, G, Höschel, I, Hofmann, Z, Hölemann, J, Hünerbein, A, Jafariserajehlou, S, Jäkel, E, Jacobi, C, Janout, M, Jansen, F, Jourdan, O, Jurányi, Z, Kalesse-Los, H, Kanzow, T, Käthner, R, Kliesch, LL, Klingebiel, M, Knudsen, EM, Kovács, T, Körtke, W, Krampe, D, Kretzschmar, J, Kreyling, D, Kulla, B, Kunkel, D, Lampert, A, Lauer, M, Lelli, L, von Lerber, A, Linke, O, Löhnert, U, Lonardi, M, Losa, SN, Losch, M, Maahn, M, Mech, M, Mei, L, Mertes, S, Metzner, E, Mewes, D, Michaelis, J, Mioche, G, Moser, M, Nakoudi, K, Neggers, R, Neuber, R, Nomokonova, T, Oelker, J, Papakonstantinou-Presvelou, I, Pätzold, F, Pefanis, V, Pohl, C, van Pinxteren, M, Radovan, A, Rhein, M, Rex, M, Richter, A, Risse, N, Ritter, C, Rostosky, P, Rozanov, VV, Donoso, E Ruiz, Saavedra Garfias, P, Salzmann, M, Schacht, J, Schäfer, M, Schneider, J, Schnierstein, N, Seifert, P, Seo, S, Siebert, H, Soppa, MA, Spreen, G, Stachlewska, IS, Stapf, J, Stratmann, F, Tegen, I, Viceto, C, Voigt, C, Vountas, M, Walbröl, A, Walter, M, Wehner, B, Wex, H, Willmes, S, Zanatta, M, and Zeppenfeld, S

Abstract

Mechanisms behind the phenomenon of Arctic amplification are widely discussed. To contribute to this debate, the (AC)3 project was established in 2016 (www.ac3-tr.de/). It comprises modeling and data analysis efforts as well as observational elements. The project has assembled a wealth of ground-based, airborne, shipborne, and satellite data of physical, chemical, and meteorological properties of the Arctic atmosphere, cryosphere, and upper ocean that are available for the Arctic climate research community. Short-term changes and indications of long-term trends in Arctic climate parameters have been detected using existing and new data. For example, a distinct atmospheric moistening, an increase of regional storm activities, an amplified winter warming in the Svalbard and North Pole regions, and a decrease of sea ice thickness in the Fram Strait and of snow depth on sea ice have been identified. A positive trend of tropospheric bromine monoxide (BrO) column densities during polar spring was verified. Local marine/biogenic sources for cloud condensation nuclei and ice nucleating particles were found. Atmospheric–ocean and radiative transfer models were advanced by applying new parameterizations of surface albedo, cloud droplet activation, convective plumes and related processes over leads, and turbulent transfer coefficients for stable surface layers. Four modes of the surface radiative energy budget were explored and reproduced by simulations. To advance the future synthesis of the results, cross-cutting activities are being developed aiming to answer key questions in four focus areas: lapse rate feedback, surface processes, Arctic mixed-phase clouds, and airmass transport and transformation.

Published
2023

4. Constraints on simulated past Arctic amplification and lapse rate feedback from observations

Author

Linke, O., Quaas, J., Baumer, F., Becker, S., Chylik, J., Dahlke, S., Ehrlich, A., Handorf, D., Jacobi, C., Kalesse-Los, H., Lelli, L., Mehrdad, S., Neggers, R., Riebold, J., Saavedra Garfias, P., Schnierstein, N., Shupe, M., Smith, C., Spreen, G., Verneuil, B., Vinjamuri, K., Vountas, M., Wendisch, M., Linke, O., Quaas, J., Baumer, F., Becker, S., Chylik, J., Dahlke, S., Ehrlich, A., Handorf, D., Jacobi, C., Kalesse-Los, H., Lelli, L., Mehrdad, S., Neggers, R., Riebold, J., Saavedra Garfias, P., Schnierstein, N., Shupe, M., Smith, C., Spreen, G., Verneuil, B., Vinjamuri, K., Vountas, M., and Wendisch, M.

Abstract

The Arctic has warmed more rapidly than the global mean during the past few decades. The lapse rate feedback (LRF) has been identified as being a large contributor to the Arctic amplification (AA) of climate change. This particular feedback arises from the vertically non-uniform warming of the troposphere, which in the Arctic emerges as strong near-surface and muted free-tropospheric warming. Stable stratification and meridional energy transport are two characteristic processes that are evoked as causes for this vertical warming structure. Our aim is to constrain these governing processes by making use of detailed observations in combination with the large climate model ensemble of the sixth Coupled Model Intercomparison Project (CMIP6). We build on the result that CMIP6 models show a large spread in AA and Arctic LRF, which are positively correlated for the historical period of 1951–2014. Thus, we present process-oriented constraints by linking characteristics of the current climate to historical climate simulations. In particular, we compare a large consortium of present-day observations to co-located model data from subsets that show a weak and strong simulated AA and Arctic LRF in the past. Our analyses suggest that the vertical temperature structure of the Arctic boundary layer is more realistically depicted in climate models with weak (w) AA and Arctic LRF (CMIP6/w) in the past. In particular, CMIP6/w models show stronger inversions in the present climate for boreal autumn and winter and over sea ice, which is more consistent with the observations. These results are based on observations from the year-long Multidisciplinary Drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition in the central Arctic, long-term measurements at the Utqiaġvik site in Alaska, USA, and dropsonde temperature profiling from aircraft campaigns in the Fram Strait. In addition, the atmospheric energy transport from lower latitudes that can further mediate the warming s

Published
2023
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5. Geografia e cibo: ricerche, riflessioni e discipline a confronto

Author

Branduini, P. and Lelli, L.

Subjects
territorialisation, food landscape, territorialisation, diversity, local identity, food landscape, local identity, territorializzazione, identità locale, paesaggio del cibo, territorializzazione,diversità, identità locale, paesaggio del cibo, diversità, diversity
Published
2022

9. Reward e correlati psicopatologici nei disturbi alimentari: il ruolo della leptina

Author

Rossi E., Cassioli E., Squecco R., Baccari M. C., Maggi M., Vignozzi L., Comeglio P., Gironi V., Lelli L., Rotella F., Monteleone Alessio Maria, Ricca Valdo, Castellini Giovanni, Rossi, E., Cassioli, E., Squecco, R., Baccari, M. C., Maggi, M., Vignozzi, L., Comeglio, P., Gironi, V., Lelli, L., Rotella, F., Monteleone, Alessio Maria, Ricca, Valdo, and Castellini, Giovanni

Published
2020

10. Development of evidence-based guidelines for follow up of women treated for cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3) in Italian screening programmes

Author

Rossi, P, Iossa, A, Visioli, C, Venturelli, F, Garutti, P, Maina, G, Andersson, K, Anselmi, R, Baldoni, A, Boselli, F, Campari, C, Carozzi, F, Cianferoni, L, Costa, S, Cristiani, P, Del Mistro, A, Fantin, G, Fumia, C, Landoni, F, Lelli, L, Maggino, T, Minucci, D, Mariani, L, Piazzesi, G, Raggi, P, Ribaldone, R, Sandri, M, Spolti, N, Torrini, B, Troncone, M, Tufi, M, Venturoli, S, Rossi, PG, Visioli, CB, Andersson, KL, Carozzi, FM, Fantin, GP, Sandri, MT, Troncone, MG, Rossi, P, Iossa, A, Visioli, C, Venturelli, F, Garutti, P, Maina, G, Andersson, K, Anselmi, R, Baldoni, A, Boselli, F, Campari, C, Carozzi, F, Cianferoni, L, Costa, S, Cristiani, P, Del Mistro, A, Fantin, G, Fumia, C, Landoni, F, Lelli, L, Maggino, T, Minucci, D, Mariani, L, Piazzesi, G, Raggi, P, Ribaldone, R, Sandri, M, Spolti, N, Torrini, B, Troncone, M, Tufi, M, Venturoli, S, Rossi, PG, Visioli, CB, Andersson, KL, Carozzi, FM, Fantin, GP, Sandri, MT, and Troncone, MG

Abstract

Background: The Italian Group for Cervical Cancer Screening (GISCi) promoted the update of recommendations for post Cervical Intraepithelial Neoplasia grade 2 or 3 (CIN2/3) treatment follow up. Methods: A multidisciplinary panel including all the professionals involved in cervical cancer screening and CIN treatment was set up. Systematic reviews have been conducted searching in PubMed. The GRADEpro online tool was used for: defining and prioritizing clinical questions framed in PICOs (Population Intervention Comparator Outcomes); defining and scoring outcomes as critical, important or not important; synthetizing results of the systematic reviews in Evidence to Decision tables and to grade recommendations. Results: A systematic review identified the main prognostic factors, but these have almost no impact in HPV-negative women. Six questions were prioritized for the first phase: 3 about the test (Pap, HPV-DNA or Pap + HPV cotesting or co-testing + colposcopy); 1 about the number of episodes before returning to screening; 2 about the timing of episodes. For the test accuracy direct evidence was available, while for other questions mostly indirect evidence was retrieved in systematic reviews. Conclusions: The panel recommends HPV test or co-testing (conditional either the two), but not Pap test as follow up test (strong). Colposcopy can be added to assess surgical outcomes (conditional either yes or not). Two episodes instead of one, before referring women to regular screening, should be preferred (conditional). The first episode should be 6 months (vs. 12) after treatment (strong), in order to avoid progression of undiagnosed prevalent invasive cancers; the interval between first and second episode may be either 6 or 12 months (conditional).

Published
2021

13. Development of evidence-based guidelines for follow up of women treated for cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3) in Italian screening programmes

Author

Rossi, PG, Iossa, A, Visioli, CB, Venturelli, F, Garutti, P, Maina, G, Andersson, KL, Anselmi, R, Baldoni, A, Boselli, F, Campari, C, Carozzi, FM, Cianferoni, L, Costa, S, Cristiani, P, Del Mistro, A, Fantin, GP, Fumia, C, Landoni, F, Lelli, L, Maggino, T, Minucci, D, Mariani, L, Piazzesi, G, Raggi, P, Ribaldone, R, Sandri, MT, Spolti, N, Torrini, B, Troncone, MG, Tufi, M, Venturoli, S, Rossi, P, Iossa, A, Visioli, C, Venturelli, F, Garutti, P, Maina, G, Andersson, K, Anselmi, R, Baldoni, A, Boselli, F, Campari, C, Carozzi, F, Cianferoni, L, Costa, S, Cristiani, P, Del Mistro, A, Fantin, G, Fumia, C, Landoni, F, Lelli, L, Maggino, T, Minucci, D, Mariani, L, Piazzesi, G, Raggi, P, Ribaldone, R, Sandri, M, Spolti, N, Torrini, B, Troncone, M, Tufi, M, and Venturoli, S

Subjects
Human papillomavirus, Evidence-based medicine, medicine.medical_specialty, Evidence-based practice, Obstetrics, business.industry, Obstetrics and Gynecology, Guidelines, Guideline, Cervical cancer, Cervical intraepithelial neoplasia (CIN) grade 2 or grade 3, Posttreatment follow up, Test of cure, Human papillomaviru, Oncology, Cervical intraepithelial neoplasia grade 2, medicine, business
Abstract

Background: The Italian Group for Cervical Cancer Screening (GISCi) promoted the update of recommendations for post Cervical Intraepithelial Neoplasia grade 2 or 3 (CIN2/3) treatment follow up. Methods: A multidisciplinary panel including all the professionals involved in cervical cancer screening and CIN treatment was set up. Systematic reviews have been conducted searching in PubMed. The GRADEpro online tool was used for: defining and prioritizing clinical questions framed in PICOs (Population Intervention Comparator Outcomes); defining and scoring outcomes as critical, important or not important; synthetizing results of the systematic reviews in Evidence to Decision tables and to grade recommendations. Results: A systematic review identified the main prognostic factors, but these have almost no impact in HPV-negative women. Six questions were prioritized for the first phase: 3 about the test (Pap, HPV-DNA or Pap + HPV cotesting or co-testing + colposcopy); 1 about the number of episodes before returning to screening; 2 about the timing of episodes. For the test accuracy direct evidence was available, while for other questions mostly indirect evidence was retrieved in systematic reviews. Conclusions: The panel recommends HPV test or co-testing (conditional either the two), but not Pap test as follow up test (strong). Colposcopy can be added to assess surgical outcomes (conditional either yes or not). Two episodes instead of one, before referring women to regular screening, should be preferred (conditional). The first episode should be 6 months (vs. 12) after treatment (strong), in order to avoid progression of undiagnosed prevalent invasive cancers; the interval between first and second episode may be either 6 or 12 months (conditional).

Published
2021
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16. Probability of major depression classification based on the SCID, CIDI, and MINI diagnostic interviews: A synthesis of three individual participant data meta-analyses

Author

Wu, Y. Levis, B. Ioannidis, J.P.A. Benedetti, A. Thombs, B.D. Sun, Y. He, C. Krishnan, A. Bhandari, P.M. Neupane, D. Negeri, Z. Imran, M. Rice, D.B. Riehm, K.E. Saadat, N. Azar, M. Levis, A.W. Sanchez, T.A. Chiovitti, M.J. Yan, X.W. Boruff, J. Kloda, L.A. Cuijpers, P. Gilbody, S. McMillan, D. Patten, S.B. Shrier, I. Ziegelstein, R.C. Comeau, L. Mitchell, N.D. Tonelli, M. Vigod, S.N. Henry, M. Ismail, Z. Loiselle, C.G. Akena, D.H. Al-Adawi, S. Alamri, S.H. Alvarado, R. Alvarado-Esquivel, C. Amtmann, D. Arroll, B. Ayalon, L. Bakare, M.O. Baradaran, H.R. Barnes, J. Bavle, A.D. Beck, C.T. Beraldi, A. Bernstein, C.N. Bhana, A. Bindt, C. Bombardier, C.H. Boyce, P.M. Büel-Drabe, N. Buji, R.I. Bunevicius, A. Butnoriene, J. Bunevicius, R. Butterworth, P. Carter, G. Chagas, M.H. Chan, J.C.N. Chan, L.F. Chaudron, L.H. Chen, C.-K. Cholera, R. Clover, K. Conroy, R.M. Conway, A. Conwell, Y. Correa, H. Castro E Couto, T. Cukor, D. Dabscheck, E. Daray, F.M. De Figueiredo, F.P. De Man-Van Ginkel, J.M. Diez-Quevedo, C. Douven, E. Downing, M.G. Eapen, V. Fann, J.R. Feinstein, A. Ferentinos, P.P. Fernandes, M. Field, S. Figueiredo, B. Fischer, F.H. Fisher, J.R.W. Flint, A.J. Fujimori, M. Fung, D.S.S. Gallagher, P. Gandy, M. Garcia-Esteve, L. Garman, E.C. Gelaye, B. Gholizadeh, L. Giardinelli, L. Gibson, L.J. Goodyear-Smith, F. Grassi, L. Green, E.P. Greeno, C.G. Hall, B.J. Hantsoo, L. Haroz, E.E. Harter, M. Hegerl, U. Helle, N. Hides, L. Hobfoll, S.E. Honikman, S. Howard, L.M. Hudson, M. Hyphantis, T. Inagaki, M. Jenewein, J. Jeon, H.J. Jette, N. Keller, M. Khalifa, D.S. Khamseh, M.E. Kiely, K.M. Kim, S.-W. Kjargaard, M. Kohler, S. Kohlhoff, J. Kohrt, B.A. Kozinszky, Z. Kusminskas, L. Kwan, Y. Lamers, F. Lara, M.A. Lelli, L. Leonardou, A.A. Levin-Aspenson, H.F. Lotrakul, M. Loureiro, S.R. Lowe, B. Luitel, N.P. Lund, C. Maes, M. Marrie, R.A. Marsh, L. Martin-Santos, R. Marx, B.P. Massardo, L. Matsuoka, Y. Mehner, A. Meuti, V. Michopoulos, I. Misery, L. Sidik, S.M. Munhoz, T.N. Muramatsu, K. Radoš, S.N. Nakku, J.E.M. Navarrete, L. Garcia, P.N. Navines, R. Nishi, D. O'Donnell, M.L. Luwa E-Andjafono, D.O. Osório, F.L. Öztürk, A. Peceliuniene, J. Pence, B.W. Persoons, P. Picardi, A. Pintor, L. Ponsford, J.L. Pugh, S.L. Quinn, T.J. Rancans, E. Rathod, S.D. Reme, S.E. Reuter, K. Robertson-Blackmore, E. Rochat, T.J. Rooney, A.G. Rowe, H.J. Sánchez-González, R. Santos, I.S. Schram, M.T. Schwarzbold, M.L. Cankorur, V.S. Shaaban, J. Sharpe, L. Shinn, E.H. Sidebottom, A. Simard, S. Simning, A. Singer, S. Siu, B.W.M. Skalkidou, A. Spangenberg, L. Stafford, L. Stein, A. Stewart, R.C. Stone, J. Su, K.-P. Sultan, S. Sundström-Poromaa, I. Sung, S.C. Suzuki, K. Tadinac, M. Tan, P.L.L. Tandon, S.D. Taylor-Rowan, M. Teixeira, A.L. Tendais, I. Thiagayson, P. Tiringer, I. Töreki, A. Torres-Giménez, A. Tran, T.D. Trevillion, K. Tung, K.-Y. Turner, A. Turner, K. Van Der Feltz-Cornelis, C.M. Van Heyningen, T. Van Weert, H.C. Vega-Dienstmaier, J.M. Vöhringer, P.A. Wagner, L.I. Walterfang, M. Wang, J.L. Wang, W. Wang, L.-J. White, J. Wong, D.K. Wynter, K. Yamada, M. Yonkers, K.A. Zeng, Q.Z. Zhang, Y. DEPRESsion Screening Data (DEPRESSD) Collaboration

Abstract

Introduction: Three previous individual participant data meta-analyses (IPDMAs) reported that, compared to the Structured Clinical Interview for the DSM (SCID), alternative reference standards, primarily the Composite International Diagnostic Interview (CIDI) and the Mini International Neuropsychiatric Interview (MINI), tended to misclassify major depression status, when controlling for depression symptom severity. However, there was an important lack of precision in the results. Objective: To compare the odds of the major depression classification based on the SCID, CIDI, and MINI. Methods: We included and standardized data from 3 IPDMA databases. For each IPDMA, separately, we fitted binomial generalized linear mixed models to compare the adjusted odds ratios (aORs) of major depression classification, controlling for symptom severity and characteristics of participants, and the interaction between interview and symptom severity. Next, we synthesized results using a DerSimonian-Laird random-effects meta-analysis. Results: In total, 69,405 participants (7,574 [11%] with major depression) from 212 studies were included. Controlling for symptom severity and participant characteristics, the MINI (74 studies; 25,749 participants) classified major depression more often than the SCID (108 studies; 21,953 participants; aOR 1.46; 95% confidence interval [CI] 1.11-1.92]). Classification odds for the CIDI (30 studies; 21,703 participants) and the SCID did not differ overall (aOR 1.19; 95% CI 0.79-1.75); however, as screening scores increased, the aOR increased less for the CIDI than the SCID (interaction aOR 0.64; 95% CI 0.52-0.80). Conclusions: Compared to the SCID, the MINI classified major depression more often. The odds of the depression classification with the CIDI increased less as symptom levels increased. Interpretation of research that uses diagnostic interviews to classify depression should consider the interview characteristics. © 2020

Published
2020

27. Eating disorders and sexuality: A complex relationship

Author

Ricca Valdo, Castellini Giovanni, Lelli L., Rotella F., Monteleone Alessio Maria, Maggi M, Ricca, Valdo, Castellini, Giovanni, Lelli, L., Rotella, F., Monteleone, Alessio Maria, and Maggi, M

Published
2017

28. Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis

Author

Levis, B, McMillan, D, Sun, Y, He, C, Rice, DB, Krishnan, A, Wu, Y, Azar, M, Sanchez, TA, Chiovitti, MJ, Bhandari, PM, Neupane, D, Saadat, N, Riehm, KE, Imran, M, Boruff, JT, Cuijpers, P, Gilbody, S, Ioannidis, JPA, Kloda, LA, Patten, SB, Shrier, I, Ziegelstein, RC, Comeau, L, Mitchell, ND, Tonelli, M, Vigod, SN, Aceti, F, Alvarado, R, Alvarado-Esquivel, C, Bakare, MO, Barnes, J, Beck, CT, Bindt, C, Boyce, PM, Bunevicius, A, Couto, TCE, Chaudron, LH, Correa, H, de Figueiredo, FP, Eapen, V, Fernandes, M, Figueiredo, B, Fisher, JRW, Garcia-Esteve, L, Giardinelli, L, Helle, N, Howard, LM, Khalifa, DS, Kohlhoff, J, Kusminskas, L, Kozinszky, Z, Lelli, L, Leonardou, AA, Lewis, BA, Maes, M, Meuti, V, Nakić Radoš, S, Navarro García, P, Nishi, D, Okitundu Luwa E-Andjafono, D, Robertson-Blackmore, E, Rochat, TJ, Rowe, HJ, Siu, BWM, Skalkidou, A, Stein, A, Stewart, RC, Su, KP, Sundström-Poromaa, I, Tadinac, M, Tandon, SD, Tendais, I, Thiagayson, P, Töreki, A, Torres-Giménez, A, Tran, TD, Trevillion, K, Turner, K, Vega-Dienstmaier, JM, Wynter, K, Yonkers, KA, Benedetti, A, Thombs, BD, Levis, B, McMillan, D, Sun, Y, He, C, Rice, DB, Krishnan, A, Wu, Y, Azar, M, Sanchez, TA, Chiovitti, MJ, Bhandari, PM, Neupane, D, Saadat, N, Riehm, KE, Imran, M, Boruff, JT, Cuijpers, P, Gilbody, S, Ioannidis, JPA, Kloda, LA, Patten, SB, Shrier, I, Ziegelstein, RC, Comeau, L, Mitchell, ND, Tonelli, M, Vigod, SN, Aceti, F, Alvarado, R, Alvarado-Esquivel, C, Bakare, MO, Barnes, J, Beck, CT, Bindt, C, Boyce, PM, Bunevicius, A, Couto, TCE, Chaudron, LH, Correa, H, de Figueiredo, FP, Eapen, V, Fernandes, M, Figueiredo, B, Fisher, JRW, Garcia-Esteve, L, Giardinelli, L, Helle, N, Howard, LM, Khalifa, DS, Kohlhoff, J, Kusminskas, L, Kozinszky, Z, Lelli, L, Leonardou, AA, Lewis, BA, Maes, M, Meuti, V, Nakić Radoš, S, Navarro García, P, Nishi, D, Okitundu Luwa E-Andjafono, D, Robertson-Blackmore, E, Rochat, TJ, Rowe, HJ, Siu, BWM, Skalkidou, A, Stein, A, Stewart, RC, Su, KP, Sundström-Poromaa, I, Tadinac, M, Tandon, SD, Tendais, I, Thiagayson, P, Töreki, A, Torres-Giménez, A, Tran, TD, Trevillion, K, Turner, K, Vega-Dienstmaier, JM, Wynter, K, Yonkers, KA, Benedetti, A, and Thombs, BD

Abstract

Objectives: A previous individual participant data meta-analysis (IPDMA) identified differences in major depression classification rates between different diagnostic interviews, controlling for depressive symptoms on the basis of the Patient Health Questionnaire-9. We aimed to determine whether similar results would be seen in a different population, using studies that administered the Edinburgh Postnatal Depression Scale (EPDS) in pregnancy or postpartum. Methods: Data accrued for an EPDS diagnostic accuracy IPDMA were analysed. Binomial generalised linear mixed models were fit to compare depression classification odds for the Mini International Neuropsychiatric Interview (MINI), Composite International Diagnostic Interview (CIDI), and Structured Clinical Interview for DSM (SCID), controlling for EPDS scores and participant characteristics. Results: Among fully structured interviews, the MINI (15 studies, 2,532 participants, 342 major depression cases) classified depression more often than the CIDI (3 studies, 2,948 participants, 194 major depression cases; adjusted odds ratio [aOR] = 3.72, 95% confidence interval [CI] [1.21, 11.43]). Compared with the semistructured SCID (28 studies, 7,403 participants, 1,027 major depression cases), odds with the CIDI (interaction aOR = 0.88, 95% CI [0.85, 0.92]) and MINI (interaction aOR = 0.95, 95% CI [0.92, 0.99]) increased less as EPDS scores increased. Conclusion: Different interviews may not classify major depression equivalently.

Published
2019

35. Aberrant salience: trait or state?

Author

Tofani, T., primary, Ciampi, E., additional, Campone, B., additional, Corsi, E., additional, Baschirotto, C., additional, Appignanesi, C., additional, Mallardo, L., additional, Godini, L., additional, Tarchiani, T., additional, Pietrini, F., additional, Lelli, L., additional, Ricca, V., additional, and Ballerini, A., additional

Published
2016
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37. Radiative transfer in the oxygen A-band and its application to cloud remote sensing

Author

Lelli, L., Kokhanovsky, A. A., Rozanov, V. V., Burrows, J. P., and ESA

Subjects
Clouds, Radiative Transfer, Oxygen A-band, Earth Sciences, lcsh:Science (General), lcsh:Q1-390
Abstract

Detection of clouds and retrieval of their properties (top and bottom altitude, optical thickness) with satellite-based spectrometers needs the solution of radiative transfer in the atmosphere. Depending on the application needed for and instrument capabilities, a trade-off choice has to be made between accuracy and speed. This study aims to characterise the range of applicability of analytical asymptotic equations to real scenarios. It has been found that the errors, introduced with approximate parameterisations, are within reasonable ranges both in absolute and relative values.

Published
2011

47. Conservazione della biodiversità in specie forestali minacciate di depauperamento genetico: il caso del pino loricato (Pinus leucodermis Ant.)

Author

Bucci G, Lelli L, and Vendramin GG

Subjects
Pinus leucodemis, Biodivesità forestale, Conservation genetics
Abstract

Al fine di valutare la divergenza genetica tra 2 popolazioni greche e 5 popolazioni italiane di Pinus leucodermis, sono stati utlizzati 23 marcatori mendeliani ottenuti con tecnica RAPD e 16 marcatori allozimici precedentemente messi a punto. Attraverso ricampionamento numerico delle frequenze alleliche (bootstrap) sono stati ottenuti gli intervalli di confidenza dei valori di divergenza osservati. La differenziazione genetica tra le popolazioni italiane è risultata essere circa uguale alla differenziazione osservata tra popolazioni greche ed italiane. La significatività di quest'ultima è quindi stata verificata attraverso randomizzazione dei dati di frequenza (permutation test). Dal momento che la separazione tra i due gruppi di popolazioni italiane e greche è avvenuta con tutta probabilità attorno a 10,000 anni fa, ci si attende una maggiore differenziazione tra piuttosto che entro i due gruppi. L'ipotesi formulata è dunque quella che l'elevata divergenza osservata tra le popolazioni italiane sia dovuta a deriva genetica, nel qual caso ci si attende un elevato disequilibrio tra coppie di loci neutrali non associati. La proporzione di coppie di loci che mostrano correlazione allelica significativa in ciascuna delle 5 popolazioni italiane è risultata essere maggiore di quella attesa per caso (7.95 - 10.88 %). Una stima della dimensione effettiva delle popolazioni italiane è stata effettuata sulla base del disequilibrio calcolato ed è risultata essere particolarmente limitata per 3 delle 5 popolazioni analizzate (Ne = 17.31 ± 1.88, 16.57 ± 1.73, e 31.41 ± 7.26, rispettivamente). Verranno presentate le implicazioni dei risultati ottenuti in questo studio nel campo della conservazione della biodiversità di specie forestali minacciate di estinzione.

Published
1998

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