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1. Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase.

2. Biochemical Effect of Resistance Mutations against Synergistic Inhibitors of RSV RNA Polymerase.

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3. Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate.

4. Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans

5. Structure-activity relationship analysis of mitochondrial toxicity caused by antiviral ribonucleoside analogs

6. Activation Pathway of a Nucleoside Analog Inhibiting Respiratory Syncytial Virus Polymerase

7. Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2′-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases

8. Discovery of 4′-Chloromethyl-2′-deoxy-3′,5′-di-O-isobutyryl-2′-fluorocytidine (ALS-8176), A First-in-Class RSV Polymerase Inhibitor for Treatment of Human Respiratory Syncytial Virus Infection

9. Inhibition of viral RNA polymerases by nucleoside and nucleotide analogs: therapeutic applications against positive-strand RNA viruses beyond hepatitis C virus

10. LATE BREAKER ABSTRACTS

11. Biochemical Effect of Resistance Mutations against Synergistic Inhibitors of RSV RNA Polymerase

12. Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study

13. Safety, Tolerability and Pharmacokinetics (PK) Following Single and Multiple Ascending Dosing of AL-8176 in Healthy Volunteers (HV)

14. The Anti-Respiratory Syncytial Virus (RSV) Nucleoside Analog, AL-8112, and Its Orally Bioavailable Prodrug, AL-8176, Exhibit a High Barrier to the Emergence of Viral Resistance

15. Population PK/PD Modeling of Human Respiratory Syncytial Virus Infection and the Antiviral Effect of AL-8176

16. Efficiency of Incorporation and Chain Termination Determines the Inhibition Potency of 2′-Modified Nucleotide Analogs against Hepatitis C Virus Polymerase

17. Synthesis and biological activities of a phosphorodithioate analog of 2′, 5′-oligoadenylate

19. The development of a monoclonal antibody specific for a 2(')-C-allyl modification of uridine, and its use in the localization of ribozymes in vivo

20. Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2'-modified nucleosides

21. LB-1Treatment with Oral ALS-008176, a Nucleoside Analog, Rapidly Reduces RSV Viral Load and Clinical Disease Severity in a Healthy Volunteer Challenge Study

22. [Untitled]

23. PS2-39 Development of a hyperglycosylated IFN alfacon1 (CIFN): Towards once a month dosing for antiviral therapy

24. Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5′-monophosphates bearing a biodegradable protecting group

25. Steric Interference Modification of the Hammerhead Ribozyme